The Experts below are selected from a list of 267 Experts worldwide ranked by ideXlab platform

Allan D. Spigelman - One of the best experts on this subject based on the ideXlab platform.

  • preventive measures in Peutz Jeghers Syndrome
    Familial Cancer, 2001
    Co-Authors: Daniel R Mcgrath, Allan D. Spigelman
    Abstract:

    Peutz-Jeghers Syndrome is a rare genetic disorder characterized by mucocutaneous melanin deposition, intestinal polyposis and an increased risk of cancer, both intestinal and extra-intestinal. We describe the current status of diagnosis and the methods by which the consequences of this condition can be minimized. A surveillance program for those diagnosed is also included.

  • polyposis the Peutz Jeghers Syndrome
    British Journal of Surgery, 1995
    Co-Authors: Allan D. Spigelman, P. Arese, R K S Phillips
    Abstract:

    The classical pigmentation of Peutz-Jeghers Syndrome distinguishes it immediately from the other polyposis Syndromes. Less widely appreciated than this most obvious manifestation are the pitfalls in management presented by the risk of cancer and by the performance of multiple laparotomies that also characterize this condition. An outline of these risks and an approach that minimizes them is presented.

  • Polyposis: The Peutz‐Jeghers Syndrome
    The British journal of surgery, 1995
    Co-Authors: Allan D. Spigelman, P. Arese, Robin K. S. Phillips
    Abstract:

    The classical pigmentation of Peutz-Jeghers Syndrome distinguishes it immediately from the other polyposis Syndromes. Less widely appreciated than this most obvious manifestation are the pitfalls in management presented by the risk of cancer and by the performance of multiple laparotomies that also characterize this condition. An outline of these risks and an approach that minimizes them is presented.

Yi-kyeong Chun - One of the best experts on this subject based on the ideXlab platform.

  • A rare case of gastric-type mucinous adenocarcinoma in a woman with Peutz-Jeghers Syndrome
    Obstetrics & gynecology science, 2019
    Co-Authors: Yeorae Kim, Eun Yi Kim, Tae Jin Kim, Kyung Taek Lim, Ki Heon Lee, Yi-kyeong Chun
    Abstract:

    Adenocarcinoma of the cervix is less common than squamous cell carcinoma. Minimal deviation adenocarcinoma (adenoma malignum) is considered an extremely well-differentiated variant of GAS. An association exists between GAS and Peutz-Jeghers Syndrome, which is a rare autosomal dominant disorder characterized by mucocutaneous pigmentation and multiple hamartomatous polyps in the gastrointestinal tracts. The incidence of GAS in patients with Peutz-Jeghers Syndrome is estimated to be 11-17%. We present a rare case of adenoma malignum, diagnosed using colposcopic biopsy in a woman with Peutz-Jeghers Syndrome, which was histopathologically confirmed to be GAS after surgery.

Thomas J. Mcgarrity - One of the best experts on this subject based on the ideXlab platform.

  • findings from the Peutz Jeghers Syndrome registry of uruguay
    PLOS ONE, 2013
    Co-Authors: Asadur Tchekmedyian, Christopher I Amos, Sherri J Bale, Dakai Zhu, Stefan T Arold, Joaquin Berrueta, Natalie Nabon, Thomas J. Mcgarrity
    Abstract:

    Background Peutz-Jeghers Syndrome (PJS) is characterized by intestinal polyposis, mucocutaneous pigmentation and an increased cancer risk, usually caused by mutations of the STK11 gene. This study collected epidemiological, clinical and genetic data from all Uruguayan PJS patients.

  • Peutz-Jeghers Syndrome
    The American journal of gastroenterology, 2000
    Co-Authors: Thomas J. Mcgarrity, Howard E. Kulin, Richard J. Zaino
    Abstract:

    Peutz-Jeghers Syndrome (PJS) is an unusual polyposis Syndrome that has enjoyed a rich and somewhat confusing history. Mucocutaneous pigmentation and diffuse gastrointestinal hamartomas are the hallmark features of this autosomal dominant inherited condition. Peutz-Jeghers Syndrome is now also recognized as a cancer predisposition Syndrome. In this review, we highlight the historical aspects of PJS polyposis with special emphasis on its extraintestinal manifestations, particularly genital tract tumors. A PJS management scheme for clinicians is included.

Xiu-jie Wang - One of the best experts on this subject based on the ideXlab platform.

  • Clinical Presentations and Surgical Approach of Acute Intussusception Caused by Peutz–Jeghers Syndrome in Adults
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2011
    Co-Authors: Hong Wang, Ting Luo, Wen-qu Liu, Yan Huang, Xiu-jie Wang
    Abstract:

    Introduction Peutz–Jeghers Syndrome is a rare autosomal dominantly inherited disease characterized by mucocutaneous pigmentations and gastrointestinal polyps. The polyps are located predominantly in the small intestine and usually cause intussusceptions. Adult intussusception caused by Peutz–Jeghers Syndrome occurs very rarely. The purpose of this study was to analyze the clinical characteristics, preoperative diagnosis, and surgical management of Peutz–Jeghers Syndrome associated with acute intussusception in adult patients.

  • clinical presentations and surgical approach of acute intussusception caused by Peutz Jeghers Syndrome in adults
    Journal of Gastrointestinal Surgery, 2011
    Co-Authors: Hong Wang, Ting Luo, Wen-qu Liu, Yan Huang, Xiu-jie Wang
    Abstract:

    Introduction Peutz–Jeghers Syndrome is a rare autosomal dominantly inherited disease characterized by mucocutaneous pigmentations and gastrointestinal polyps. The polyps are located predominantly in the small intestine and usually cause intussusceptions. Adult intussusception caused by Peutz–Jeghers Syndrome occurs very rarely. The purpose of this study was to analyze the clinical characteristics, preoperative diagnosis, and surgical management of Peutz–Jeghers Syndrome associated with acute intussusception in adult patients.

Yeorae Kim - One of the best experts on this subject based on the ideXlab platform.

  • A rare case of gastric-type mucinous adenocarcinoma in a woman with Peutz-Jeghers Syndrome
    Obstetrics & gynecology science, 2019
    Co-Authors: Yeorae Kim, Eun Yi Kim, Tae Jin Kim, Kyung Taek Lim, Ki Heon Lee, Yi-kyeong Chun
    Abstract:

    Adenocarcinoma of the cervix is less common than squamous cell carcinoma. Minimal deviation adenocarcinoma (adenoma malignum) is considered an extremely well-differentiated variant of GAS. An association exists between GAS and Peutz-Jeghers Syndrome, which is a rare autosomal dominant disorder characterized by mucocutaneous pigmentation and multiple hamartomatous polyps in the gastrointestinal tracts. The incidence of GAS in patients with Peutz-Jeghers Syndrome is estimated to be 11-17%. We present a rare case of adenoma malignum, diagnosed using colposcopic biopsy in a woman with Peutz-Jeghers Syndrome, which was histopathologically confirmed to be GAS after surgery.