The Experts below are selected from a list of 19116 Experts worldwide ranked by ideXlab platform
Hisahiro Yoshida - One of the best experts on this subject based on the ideXlab platform.
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Peyers Patch Organogenesis as a Programmed Inflammation: a Hypothetical Model
Cytokine & Growth Factor Reviews, 1998Co-Authors: Shin-ichi Nishikawa, Hideyuki Oh-hashi, Kenya Honda, Satomi Nishikawa, Hisahiro YoshidaAbstract:Abstract Gene-knock-out studies implicate roles of lymphotoxin (LT) α β and LTβR in the initial phase of Peyers Patch (PP) organogenesis. We recently identified the requirement of IL-7Rα/γc/Jak3 signal in LTα β production of IL-7Rα+ cells. These observations lead us to a hypothetical model for PP organogenesis with three cellular components. The first is the producer of the ligand for IL-7Rα, which then stimulate the IL-7Rα+ cells to produce LTα β, activating the LTβR+ cells to form an organizing center for PP organogenesis. This model is similar to that of inflammation, suggesting that PP organogenesis is a programmed version of inflammation.
Shin-ichi Nishikawa - One of the best experts on this subject based on the ideXlab platform.
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Peyers Patch Organogenesis as a Programmed Inflammation: a Hypothetical Model
Cytokine & Growth Factor Reviews, 1998Co-Authors: Shin-ichi Nishikawa, Hideyuki Oh-hashi, Kenya Honda, Satomi Nishikawa, Hisahiro YoshidaAbstract:Abstract Gene-knock-out studies implicate roles of lymphotoxin (LT) α β and LTβR in the initial phase of Peyers Patch (PP) organogenesis. We recently identified the requirement of IL-7Rα/γc/Jak3 signal in LTα β production of IL-7Rα+ cells. These observations lead us to a hypothetical model for PP organogenesis with three cellular components. The first is the producer of the ligand for IL-7Rα, which then stimulate the IL-7Rα+ cells to produce LTα β, activating the LTβR+ cells to form an organizing center for PP organogenesis. This model is similar to that of inflammation, suggesting that PP organogenesis is a programmed version of inflammation.
Hideyuki Oh-hashi - One of the best experts on this subject based on the ideXlab platform.
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Peyers Patch Organogenesis as a Programmed Inflammation: a Hypothetical Model
Cytokine & Growth Factor Reviews, 1998Co-Authors: Shin-ichi Nishikawa, Hideyuki Oh-hashi, Kenya Honda, Satomi Nishikawa, Hisahiro YoshidaAbstract:Abstract Gene-knock-out studies implicate roles of lymphotoxin (LT) α β and LTβR in the initial phase of Peyers Patch (PP) organogenesis. We recently identified the requirement of IL-7Rα/γc/Jak3 signal in LTα β production of IL-7Rα+ cells. These observations lead us to a hypothetical model for PP organogenesis with three cellular components. The first is the producer of the ligand for IL-7Rα, which then stimulate the IL-7Rα+ cells to produce LTα β, activating the LTβR+ cells to form an organizing center for PP organogenesis. This model is similar to that of inflammation, suggesting that PP organogenesis is a programmed version of inflammation.
Kenya Honda - One of the best experts on this subject based on the ideXlab platform.
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Peyers Patch Organogenesis as a Programmed Inflammation: a Hypothetical Model
Cytokine & Growth Factor Reviews, 1998Co-Authors: Shin-ichi Nishikawa, Hideyuki Oh-hashi, Kenya Honda, Satomi Nishikawa, Hisahiro YoshidaAbstract:Abstract Gene-knock-out studies implicate roles of lymphotoxin (LT) α β and LTβR in the initial phase of Peyers Patch (PP) organogenesis. We recently identified the requirement of IL-7Rα/γc/Jak3 signal in LTα β production of IL-7Rα+ cells. These observations lead us to a hypothetical model for PP organogenesis with three cellular components. The first is the producer of the ligand for IL-7Rα, which then stimulate the IL-7Rα+ cells to produce LTα β, activating the LTβR+ cells to form an organizing center for PP organogenesis. This model is similar to that of inflammation, suggesting that PP organogenesis is a programmed version of inflammation.
Satomi Nishikawa - One of the best experts on this subject based on the ideXlab platform.
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Peyers Patch Organogenesis as a Programmed Inflammation: a Hypothetical Model
Cytokine & Growth Factor Reviews, 1998Co-Authors: Shin-ichi Nishikawa, Hideyuki Oh-hashi, Kenya Honda, Satomi Nishikawa, Hisahiro YoshidaAbstract:Abstract Gene-knock-out studies implicate roles of lymphotoxin (LT) α β and LTβR in the initial phase of Peyers Patch (PP) organogenesis. We recently identified the requirement of IL-7Rα/γc/Jak3 signal in LTα β production of IL-7Rα+ cells. These observations lead us to a hypothetical model for PP organogenesis with three cellular components. The first is the producer of the ligand for IL-7Rα, which then stimulate the IL-7Rα+ cells to produce LTα β, activating the LTβR+ cells to form an organizing center for PP organogenesis. This model is similar to that of inflammation, suggesting that PP organogenesis is a programmed version of inflammation.