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V I Simagina - One of the best experts on this subject based on the ideXlab platform.

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  • reaction of 3 pHenyl 3 aminoquinoline 2 4 diones with isothiocyanates facile access to novel spiro linked 2 thioxoimidazolidine oxindoles and imidazoline 2 thiones
    Tetrahedron, 2010
    Co-Authors: Antonin Klasek, Antonin Lycka, Ivan Miksik, Ales Růžicka
    Abstract:

    Abstract 3-pHenyl-3-amino-1H,3H-quinoline-2,4-diones (1) react with alkyl or aryl isothiocyanates to give novel 9b-hydroxy-3a-pHenyl-1,2,3,3a-tetrahydro-2-thioxo-5H-imidazo[4,5-c]quinolin-4(9bH)-ones in high yields. These compounds rearrange in boiling acetic acid or concentrated hydrochloric acid to give novel 5-pHenyl-2-thioxospiro[4H-imidazol-4,3′-[3H]indol]-2′(1′H,3H)-ones, 5-hydroxy-5-pHenyl-2-thioxospiro[imidazolidine-4,3′-[3H]indol]-2′-ones and (2-methylaminopHenyl)-5-pHenyl-1H-imidazole-2(3H)-thiones. All compounds were characterized by their 1H, 13C, IR and MS data, and in some cases also by 15N NMR data. The structures and compositions of four compounds were confirmed by single crystal X-ray diffraction.

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O V Netskina - One of the best experts on this subject based on the ideXlab platform.