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Ryoji Tsuboi - One of the best experts on this subject based on the ideXlab platform.
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immediate type hypersensitivity and late Phase Reaction occurred consecutively in a patient receiving ethambutol and levofloxacin
Allergy Asthma & Clinical Immunology, 2018Co-Authors: Yukihiko Kato, Miho Nakasu, Yu Sato, Ryoji TsuboiAbstract:We experienced a rare case of immediate type hypersensitivity and late Phase Reaction to anti-tubercular therapy consisting of ethambutol and levofloxacin, which occurred in close succession, giving the appearance of a single, continuous Reaction to one drug. The patient was a man in his 70’s who began therapy consisting of isoniazide, rifampicin, and ethambutol for pulmonary tuberculosis. Since the patient had a drug eruption within several hours after the start of his treatment, his Reaction to ethambutol was assessed first among the three suspected drugs using an oral challenge test. Levofloxacin, which was not among the suspected drugs, was administered with ethambutol in order to avoid drug resistance resulting from the administration of a single drug. The patient experienced pruritus within 1 h. We observed a well-defined, edematous erythema with induration, which persisted for several days after the patient received the two drugs. Next, skin tests were performed with ethambutol and levofloxacin. The skin Reaction to ethambutol and levofloxacin consisted of two different types of allergic Reaction, a immediate type Reaction and Phase Reaction. This is the first report of a late Phase Reaction and immediate type hypersensitivity occurring in quick succession in the same patient. Subsequent skin tests were able to prove the presence of these two different types of allergic Reactions.
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Immediate type hypersensitivity and late Phase Reaction occurred consecutively in a patient receiving ethambutol and levofloxacin
BMC, 2018Co-Authors: Yukihiko Kato, Miho Nakasu, Yu Sato, Ryoji TsuboiAbstract:Abstract Background We experienced a rare case of immediate type hypersensitivity and late Phase Reaction to anti-tubercular therapy consisting of ethambutol and levofloxacin, which occurred in close succession, giving the appearance of a single, continuous Reaction to one drug. Case presentation The patient was a man in his 70’s who began therapy consisting of isoniazide, rifampicin, and ethambutol for pulmonary tuberculosis. Since the patient had a drug eruption within several hours after the start of his treatment, his Reaction to ethambutol was assessed first among the three suspected drugs using an oral challenge test. Levofloxacin, which was not among the suspected drugs, was administered with ethambutol in order to avoid drug resistance resulting from the administration of a single drug. The patient experienced pruritus within 1 h. We observed a well-defined, edematous erythema with induration, which persisted for several days after the patient received the two drugs. Next, skin tests were performed with ethambutol and levofloxacin. The skin Reaction to ethambutol and levofloxacin consisted of two different types of allergic Reaction, a immediate type Reaction and Phase Reaction. Conclusion This is the first report of a late Phase Reaction and immediate type hypersensitivity occurring in quick succession in the same patient. Subsequent skin tests were able to prove the presence of these two different types of allergic Reactions
Paul Marshall - One of the best experts on this subject based on the ideXlab platform.
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An investigation of the gas-Phase Reaction of atomic bromine with disilane: implications for the Si2H5H bond strength
Chemical Physics Letters, 1993Co-Authors: Abdellatif Goumri, W. J. Yuan, Luying Ding, Paul MarshallAbstract:Article on an investigation of the gas-Phase Reaction of atomic bromine with disilane and implications for the Si2H5-H bond strength
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An investigation of the gas-Phase Reaction of atomic bromine with disilane: implications for the Si2H5H bond strength
Chemical Physics Letters, 1993Co-Authors: Abdellatif Goumri, W. J. Yuan, Luying Ding, Paul MarshallAbstract:Article on an investigation of the gas-Phase Reaction of atomic bromine with disilane and implications for the Si2H5-H bond strength.
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Investigation of the gas-Phase Reaction of trimethylsilyl radicals with hydrogen bromide: measurement of the trimethylsilyl-hydrogen bond strength
Journal of the American Chemical Society, 1993Co-Authors: Abdellatif Goumri, W. J. Yuan, Paul MarshallAbstract:Article on an investigation of the gas-Phase Reaction of trimethylsilyl radicals with HBr and measurement of the (CH₃)₃ Si-H bond strength.
Yukihiko Kato - One of the best experts on this subject based on the ideXlab platform.
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immediate type hypersensitivity and late Phase Reaction occurred consecutively in a patient receiving ethambutol and levofloxacin
Allergy Asthma & Clinical Immunology, 2018Co-Authors: Yukihiko Kato, Miho Nakasu, Yu Sato, Ryoji TsuboiAbstract:We experienced a rare case of immediate type hypersensitivity and late Phase Reaction to anti-tubercular therapy consisting of ethambutol and levofloxacin, which occurred in close succession, giving the appearance of a single, continuous Reaction to one drug. The patient was a man in his 70’s who began therapy consisting of isoniazide, rifampicin, and ethambutol for pulmonary tuberculosis. Since the patient had a drug eruption within several hours after the start of his treatment, his Reaction to ethambutol was assessed first among the three suspected drugs using an oral challenge test. Levofloxacin, which was not among the suspected drugs, was administered with ethambutol in order to avoid drug resistance resulting from the administration of a single drug. The patient experienced pruritus within 1 h. We observed a well-defined, edematous erythema with induration, which persisted for several days after the patient received the two drugs. Next, skin tests were performed with ethambutol and levofloxacin. The skin Reaction to ethambutol and levofloxacin consisted of two different types of allergic Reaction, a immediate type Reaction and Phase Reaction. This is the first report of a late Phase Reaction and immediate type hypersensitivity occurring in quick succession in the same patient. Subsequent skin tests were able to prove the presence of these two different types of allergic Reactions.
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Immediate type hypersensitivity and late Phase Reaction occurred consecutively in a patient receiving ethambutol and levofloxacin
BMC, 2018Co-Authors: Yukihiko Kato, Miho Nakasu, Yu Sato, Ryoji TsuboiAbstract:Abstract Background We experienced a rare case of immediate type hypersensitivity and late Phase Reaction to anti-tubercular therapy consisting of ethambutol and levofloxacin, which occurred in close succession, giving the appearance of a single, continuous Reaction to one drug. Case presentation The patient was a man in his 70’s who began therapy consisting of isoniazide, rifampicin, and ethambutol for pulmonary tuberculosis. Since the patient had a drug eruption within several hours after the start of his treatment, his Reaction to ethambutol was assessed first among the three suspected drugs using an oral challenge test. Levofloxacin, which was not among the suspected drugs, was administered with ethambutol in order to avoid drug resistance resulting from the administration of a single drug. The patient experienced pruritus within 1 h. We observed a well-defined, edematous erythema with induration, which persisted for several days after the patient received the two drugs. Next, skin tests were performed with ethambutol and levofloxacin. The skin Reaction to ethambutol and levofloxacin consisted of two different types of allergic Reaction, a immediate type Reaction and Phase Reaction. Conclusion This is the first report of a late Phase Reaction and immediate type hypersensitivity occurring in quick succession in the same patient. Subsequent skin tests were able to prove the presence of these two different types of allergic Reactions
Kaoru Fujimoto - One of the best experts on this subject based on the ideXlab platform.
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Supercritical-Phase Fischer-Tropsch synthesis Reaction. 2. The effective diffusion of reactant and products in the supercritical-Phase Reaction
Industrial & Engineering Chemistry Research, 1991Co-Authors: Kohshiroh Yokota, Kaoru FujimotoAbstract:A Fischer-Tropsch synthesis Reaction was conducted in a supercritical fluid medium with use of a fixed bed reactor. n-Hexane was used as the supercritical fluid. Although the rate of the Reaction and the diffusion of reactants were slightly lower than those in the gas-Phase Reaction, the removal of Reaction heat and waxy products from the catalyst surface was much more effective than in the gas-Phase Reaction. The olefin content in the hydrocarbon product was much higher in the supercritical-Phase Reaction than in the liquid-Phase Reaction or in the gas-Phase Reaction. It was attributed to the short residence time of the product in the catalyst bed for the supercritical-Phase Reaction, which was caused by the well-balanced desorption and diffusion of the products
Abdellatif Goumri - One of the best experts on this subject based on the ideXlab platform.
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An investigation of the gas-Phase Reaction of atomic bromine with disilane: implications for the Si2H5H bond strength
Chemical Physics Letters, 1993Co-Authors: Abdellatif Goumri, W. J. Yuan, Luying Ding, Paul MarshallAbstract:Article on an investigation of the gas-Phase Reaction of atomic bromine with disilane and implications for the Si2H5-H bond strength
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An investigation of the gas-Phase Reaction of atomic bromine with disilane: implications for the Si2H5H bond strength
Chemical Physics Letters, 1993Co-Authors: Abdellatif Goumri, W. J. Yuan, Luying Ding, Paul MarshallAbstract:Article on an investigation of the gas-Phase Reaction of atomic bromine with disilane and implications for the Si2H5-H bond strength.
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Investigation of the gas-Phase Reaction of trimethylsilyl radicals with hydrogen bromide: measurement of the trimethylsilyl-hydrogen bond strength
Journal of the American Chemical Society, 1993Co-Authors: Abdellatif Goumri, W. J. Yuan, Paul MarshallAbstract:Article on an investigation of the gas-Phase Reaction of trimethylsilyl radicals with HBr and measurement of the (CH₃)₃ Si-H bond strength.