The Experts below are selected from a list of 216 Experts worldwide ranked by ideXlab platform
Giancarlo Colombo - One of the best experts on this subject based on the ideXlab platform.
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Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
Phytotherapy Research, 2012Co-Authors: Alessandro Zaru, Antonella Riva, Paola Maccioni, Mauro A.m. Carai, E Bombardelli, Paolo Morazzoni, Gian Luigi Gessa, Giancarlo ColomboAbstract:Treatment with a rational combination of standardized extracts of Phaseolus vulgaris and Cynara scolymus reduced food intake and glycemia in rats. The present study was designed to assess the effect of this extract combination and of each single extract in an experimental model of food craving, made up of rats displaying exaggerated seeking and taking behaviors for a chocolate-flavoured beverage. After training to lever-respond for the chocolate-flavoured beverage, rats were treated with vehicle, Phaseolus vulgaris extract alone (200mg/kg), Cynara scolymus extract alone (400mg/kg), or combination of Phaseolus vulgaris (200mg/kg) and Cynara scolymus (400mg/kg) extracts. The Phaseolus vulgaris extract and the extract combination exerted similar and substantial decrements in the number of lever-responses and amount of self-administered chocolate-flavoured beverage; conversely, the Cynara scolymus extract was totally ineffective. These results suggest that (i) the capacity of the extract combination to reduce the self-administration of the chocolate-flavoured beverage entirely relied on the Phaseolus vulgaris extract, (ii) Phaseolus vulgaris extract may interfere with the mechanisms regulating food-related addictive-like behaviors, and (iii) combinations of Phaseolus vulgaris and Cynara scolymus extracts may possess a broad spectrum of activities, from treatment of metabolic syndrome to overweight, obesity, and possibly food-related addictive disorders. Copyright © 2012 John Wiley & Sons, Ltd.
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Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
Phytotherapy research : PTR, 2012Co-Authors: Alessandro Zaru, Antonella Riva, Paola Maccioni, Mauro A.m. Carai, E Bombardelli, Paolo Morazzoni, Gian Luigi Gessa, Giancarlo ColomboAbstract:Treatment with a rational combination of standardized extracts of Phaseolus vulgaris and Cynara scolymus reduced food intake and glycemia in rats. The present study was designed to assess the effect of this extract combination and of each single extract in an experimental model of food craving, made up of rats displaying exaggerated seeking and taking behaviors for a chocolate-flavoured beverage. After training to lever-respond for the chocolate-flavoured beverage, rats were treated with vehicle, Phaseolus vulgaris extract alone (200 mg/kg), Cynara scolymus extract alone (400 mg/kg), or combination of Phaseolus vulgaris (200 mg/kg) and Cynara scolymus (400 mg/kg) extracts. The Phaseolus vulgaris extract and the extract combination exerted similar and substantial decrements in the number of lever-responses and amount of self-administered chocolate-flavoured beverage; conversely, the Cynara scolymus extract was totally ineffective. These results suggest that (i) the capacity of the extract combination to reduce the self-administration of the chocolate-flavoured beverage entirely relied on the Phaseolus vulgaris extract, (ii) Phaseolus vulgaris extract may interfere with the mechanisms regulating food-related addictive-like behaviors, and (iii) combinations of Phaseolus vulgaris and Cynara scolymus extracts may possess a broad spectrum of activities, from treatment of metabolic syndrome to overweight, obesity, and possibly food-related addictive disorders.
Shikha Devpura - One of the best experts on this subject based on the ideXlab platform.
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Physiological and Biochemical Effects of Simulated Acid Rain on Phaseolus vulgaris Var. HUR-15
Environmentalist, 2004Co-Authors: T. I. Khan, Shikha DevpuraAbstract:Pot experiments were performed to determine the effects of simulated acid rain on Phaseolus vulgaris var. HUR-15. Seeds of Phaseolus vulgaris var. HUR-15 were exposed to simulated acid rain at pH values of 5.1, 4.1, 3.1, 2.1 and 1.1 and a control level of pH 6.8. Plants were harvested at three stages, i.e. pre, peak and post-flowering stages. Seedlings succumbed at pH 1.1. Necrosis developed on the leaves of plants treated with water of pH 2.1, resulting in adverse effect on chlorophyll content. They died after peak-flowering. Root and shoot length and dry weight were reduced with the lowering in pH. Carbohydrate, nitrogen and protein contents decreased with the decrease in pH level, adversely affecting their nutrient value.
Federico Sánchez - One of the best experts on this subject based on the ideXlab platform.
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Identification and characterization of microRNAs in Phaseolus vulgaris by high-throughput sequencing
BMC genomics, 2012Co-Authors: Pablo Pelaez, Minerva S Trejo, Luis P. Íñiguez, Georgina Estrada-navarrete, Alejandra A. Covarrubias, José L. Reyes, Federico SánchezAbstract:MicroRNAs (miRNAs) are endogenously encoded small RNAs that post-transcriptionally regulate gene expression. MiRNAs play essential roles in almost all plant biological processes. Currently, few miRNAs have been identified in the model food legume Phaseolus vulgaris (common bean). Recent advances in next generation sequencing technologies have allowed the identification of conserved and novel miRNAs in many plant species. Here, we used Illumina's sequencing by synthesis (SBS) technology to identify and characterize the miRNA population of Phaseolus vulgaris. Small RNA libraries were generated from roots, flowers, leaves, and seedlings of P. vulgaris. Based on similarity to previously reported plant miRNAs,114 miRNAs belonging to 33 conserved miRNA families were identified. Stem-loop precursors and target gene sequences for several conserved common bean miRNAs were determined from publicly available databases. Less conserved miRNA families and species-specific common bean miRNA isoforms were also characterized. Moreover, novel miRNAs based on the small RNAs were found and their potential precursors were predicted. In addition, new target candidates for novel and conserved miRNAs were proposed. Finally, we studied organ-specific miRNA family expression levels through miRNA read frequencies. This work represents the first massive-scale RNA sequencing study performed in Phaseolus vulgaris to identify and characterize its miRNA population. It significantly increases the number of miRNAs, precursors, and targets identified in this agronomically important species. The miRNA expression analysis provides a foundation for understanding common bean miRNA organ-specific expression patterns. The present study offers an expanded picture of P. vulgaris miRNAs in relation to those of other legumes.
Alessandro Zaru - One of the best experts on this subject based on the ideXlab platform.
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Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
Phytotherapy Research, 2012Co-Authors: Alessandro Zaru, Antonella Riva, Paola Maccioni, Mauro A.m. Carai, E Bombardelli, Paolo Morazzoni, Gian Luigi Gessa, Giancarlo ColomboAbstract:Treatment with a rational combination of standardized extracts of Phaseolus vulgaris and Cynara scolymus reduced food intake and glycemia in rats. The present study was designed to assess the effect of this extract combination and of each single extract in an experimental model of food craving, made up of rats displaying exaggerated seeking and taking behaviors for a chocolate-flavoured beverage. After training to lever-respond for the chocolate-flavoured beverage, rats were treated with vehicle, Phaseolus vulgaris extract alone (200mg/kg), Cynara scolymus extract alone (400mg/kg), or combination of Phaseolus vulgaris (200mg/kg) and Cynara scolymus (400mg/kg) extracts. The Phaseolus vulgaris extract and the extract combination exerted similar and substantial decrements in the number of lever-responses and amount of self-administered chocolate-flavoured beverage; conversely, the Cynara scolymus extract was totally ineffective. These results suggest that (i) the capacity of the extract combination to reduce the self-administration of the chocolate-flavoured beverage entirely relied on the Phaseolus vulgaris extract, (ii) Phaseolus vulgaris extract may interfere with the mechanisms regulating food-related addictive-like behaviors, and (iii) combinations of Phaseolus vulgaris and Cynara scolymus extracts may possess a broad spectrum of activities, from treatment of metabolic syndrome to overweight, obesity, and possibly food-related addictive disorders. Copyright © 2012 John Wiley & Sons, Ltd.
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Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
Phytotherapy research : PTR, 2012Co-Authors: Alessandro Zaru, Antonella Riva, Paola Maccioni, Mauro A.m. Carai, E Bombardelli, Paolo Morazzoni, Gian Luigi Gessa, Giancarlo ColomboAbstract:Treatment with a rational combination of standardized extracts of Phaseolus vulgaris and Cynara scolymus reduced food intake and glycemia in rats. The present study was designed to assess the effect of this extract combination and of each single extract in an experimental model of food craving, made up of rats displaying exaggerated seeking and taking behaviors for a chocolate-flavoured beverage. After training to lever-respond for the chocolate-flavoured beverage, rats were treated with vehicle, Phaseolus vulgaris extract alone (200 mg/kg), Cynara scolymus extract alone (400 mg/kg), or combination of Phaseolus vulgaris (200 mg/kg) and Cynara scolymus (400 mg/kg) extracts. The Phaseolus vulgaris extract and the extract combination exerted similar and substantial decrements in the number of lever-responses and amount of self-administered chocolate-flavoured beverage; conversely, the Cynara scolymus extract was totally ineffective. These results suggest that (i) the capacity of the extract combination to reduce the self-administration of the chocolate-flavoured beverage entirely relied on the Phaseolus vulgaris extract, (ii) Phaseolus vulgaris extract may interfere with the mechanisms regulating food-related addictive-like behaviors, and (iii) combinations of Phaseolus vulgaris and Cynara scolymus extracts may possess a broad spectrum of activities, from treatment of metabolic syndrome to overweight, obesity, and possibly food-related addictive disorders.
T. I. Khan - One of the best experts on this subject based on the ideXlab platform.
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Physiological and Biochemical Effects of Simulated Acid Rain on Phaseolus vulgaris Var. HUR-15
Environmentalist, 2004Co-Authors: T. I. Khan, Shikha DevpuraAbstract:Pot experiments were performed to determine the effects of simulated acid rain on Phaseolus vulgaris var. HUR-15. Seeds of Phaseolus vulgaris var. HUR-15 were exposed to simulated acid rain at pH values of 5.1, 4.1, 3.1, 2.1 and 1.1 and a control level of pH 6.8. Plants were harvested at three stages, i.e. pre, peak and post-flowering stages. Seedlings succumbed at pH 1.1. Necrosis developed on the leaves of plants treated with water of pH 2.1, resulting in adverse effect on chlorophyll content. They died after peak-flowering. Root and shoot length and dry weight were reduced with the lowering in pH. Carbohydrate, nitrogen and protein contents decreased with the decrease in pH level, adversely affecting their nutrient value.