The Experts below are selected from a list of 270 Experts worldwide ranked by ideXlab platform
Yasumasa Hamada - One of the best experts on this subject based on the ideXlab platform.
-
formal meta specific intramolecular friedel crafts allylic alkylation of Phenols through a spirocyclization dienone Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
-
Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols through a spirocyclization–dienone–Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
Mariko Yoshida - One of the best experts on this subject based on the ideXlab platform.
-
formal meta specific intramolecular friedel crafts allylic alkylation of Phenols through a spirocyclization dienone Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
-
Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols through a spirocyclization–dienone–Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
Tetsuhiro Nemoto - One of the best experts on this subject based on the ideXlab platform.
-
formal meta specific intramolecular friedel crafts allylic alkylation of Phenols through a spirocyclization dienone Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
-
Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols through a spirocyclization–dienone–Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
Tomoyuki Nozaki - One of the best experts on this subject based on the ideXlab platform.
-
formal meta specific intramolecular friedel crafts allylic alkylation of Phenols through a spirocyclization dienone Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
-
Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols through a spirocyclization–dienone–Phenol rearrangement cascade
Tetrahedron, 2013Co-Authors: Mariko Yoshida, Tomoyuki Nozaki, Tetsuhiro Nemoto, Yasumasa HamadaAbstract:Abstract Formal meta-specific intramolecular Friedel–Crafts allylic alkylation of Phenols was achieved based on spirocyclization–dienone–Phenol rearrangement cascades. Systematic screening of acid catalysts revealed that Sc(OTf)3 was a highly effective catalyst for dienone–Phenol rearrangement of spiro[4.5]cyclohexadienones. Using 5 mol % of Sc(OTf)3 as the promoter, various spirocyclic substrates were transformed into the corresponding Phenol derivatives in good to excellent yield. Furthermore, the one-pot sequential spirocyclization–dienone–Phenol rearrangement proceeded using a palladium and scandium multi-catalytic system or a triphenylmethyl cation single-catalyst system, providing the corresponding meta-allylated Phenol derivatives in excellent yield.
Anne S Meyer - One of the best experts on this subject based on the ideXlab platform.
-
upgrading of grape skins significance of plant cell wall structural components and extraction techniques for Phenol release
Trends in Food Science and Technology, 2006Co-Authors: Manuel Pinelo, Anis Arnous, Anne S MeyerAbstract:In grape skins, Phenols may be classified as (1) cell-wall Phenols, which are bound to polysaccharides by hydrophobic interactions and hydrogen bonds, and (2) non-cell-wall Phenols, encompassing Phenols confined in the vacuoles of plant cells and Phenols associated with the cell nucleus. The Phenolic composition of wines determines the colour quality, the sensory, and the potential health promoting properties of wines, and the extraction of Phenols from the grapes into the must and wine is to a large extent governed by how the Phenols are bound and entangled in the grape skins. Degradation of cell-wall polysaccharides is a fundamental step to improve the release of Phenols from grape skin whether this is in winemaking or in upgrading of wine pomace. Cellulases, hemicellulases, pectinases, and other enzymes able to catalyze the hydrolysis of bonds in plant cell-wall polysaccharides can be employed to decompose the cell-wall structure. In addition, novel extraction principles and optimization of extraction conditions such as temperature, solvent-to-solid ratio, use of supercritical fluids and new extraction cell designs have shown promise for optimizing the release of Phenols from grape skins for valorization of wine pomace. An in-depth knowledge of how Phenols are bound in grape skins will allow us to employ the most suitable techniques to release Phenols in order to optimize the Phenol-related properties of wine and maximize the Phenol recovery from grape byproducts.
