The Experts below are selected from a list of 2982 Experts worldwide ranked by ideXlab platform
Ahmed M. Hussein - One of the best experts on this subject based on the ideXlab platform.
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Flow injection potentiometric sensor for determination of Phenylpropanolamine hydrochloride
Arabian Journal of Chemistry, 2009Co-Authors: Yousry M. Issa, M. M. Khalil, Sayed I. M. Zayed, Ahmed M. HusseinAbstract:Abstract A new polymeric membrane electrode has been constructed for the determination of Phenylpropanolamine hydrochloride. The electrode was prepared by solubilizing the Phenylpropanolamine-phosphomolybdate ion associate into a polyvinyl chloride matrix plasticized by dibutylphthalate as a solvent mediator. The electrode showed near-Nernstian response over the concentration range of 1 × 10 −5 –1 × 10 −2 M with low detection limit of 6.3 × 10 −6 M. The electrode displays a good selectivity for Phenylpropanolamine with respect to a number of common inorganic and organic species. The electrode was successfully applied to the potentiometric determination of Phenylpropanolamine ion in its pure state and its pharmaceutical preparation in batch and flow injection conditions.
R A S White - One of the best experts on this subject based on the ideXlab platform.
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treatment of urethral sphincter mechanism incompetence in 11 bitches with a sustained release formulation of Phenylpropanolamine hydrochloride
Veterinary Record, 2002Co-Authors: Nicholas J Bacon, O Oni, R A S WhiteAbstract:Between 1995 and 1999, urethral sphincter mechanism incompetence was diagnosed in 11 bitches. They had been treated with Phenylpropanolamine hydrochloride at the recommended dose rate, but had shown no response or had become refractory to treatment. They were treated with Phenylpropanolamine hydrochloride in a sustained-release formulation combined with diphenylpyraline hydrochloride. The urinary incontinence resolved fully in six of the bitches, two of which remained continent after the treatment was withdrawn; two showed a marked improvement on daily treatment, but the other three bitches failed to respond and underwent colposuspension.
Yousry M. Issa - One of the best experts on this subject based on the ideXlab platform.
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Flow injection potentiometric sensor for determination of Phenylpropanolamine hydrochloride
Arabian Journal of Chemistry, 2009Co-Authors: Yousry M. Issa, M. M. Khalil, Sayed I. M. Zayed, Ahmed M. HusseinAbstract:Abstract A new polymeric membrane electrode has been constructed for the determination of Phenylpropanolamine hydrochloride. The electrode was prepared by solubilizing the Phenylpropanolamine-phosphomolybdate ion associate into a polyvinyl chloride matrix plasticized by dibutylphthalate as a solvent mediator. The electrode showed near-Nernstian response over the concentration range of 1 × 10 −5 –1 × 10 −2 M with low detection limit of 6.3 × 10 −6 M. The electrode displays a good selectivity for Phenylpropanolamine with respect to a number of common inorganic and organic species. The electrode was successfully applied to the potentiometric determination of Phenylpropanolamine ion in its pure state and its pharmaceutical preparation in batch and flow injection conditions.
Ali A Mutair - One of the best experts on this subject based on the ideXlab platform.
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construction and performance characterization of ion selective electrodes for potentiometric determination of Phenylpropanolamine hydrochloride applying batch and flow injection analysis techniques
Analytica Chimica Acta, 2004Co-Authors: Sayed S Badawy, Ahmed F A Youssef, Ali A MutairAbstract:Abstract New Phenylpropanolamine hydrochloride (PPA.Cl)-selective electrodes of the conventional polymer membrane type, based on incorporation of Phenylpropanolamine–tetraphenylborate (PPA–TPB) ion-pair or Phenylpropanolamine–phosphotungstate (PPA–PT) ion-associate in a poly(vinyl chloride) (PVC) membrane plasticized with dioctylphethalate (DOP) or dibutylphethalate (DBP), have been constructed. The electrodes were fully characterized in terms of the membrane composition, temperature, and pH. The electrodes were applied to the potentiometric determination of PPA.Cl in pure solutions and in pharmaceutical preparations under batch and flow injection conditions. The sensors showed fast, stable, and Nernstian slope over the concentration ranges 1.0×10 −5 to 8.91×10 −3 M and 10 −5 to 10 −2 M in the case of PPA–TPB applying batch and flow injection analysis (FIA), respectively, and 5.01×10 −6 to 1.25×10 −3 M and 10 −5 to 10 −2 M in the case of PPA–PT for batch and FIA systems, respectively. The electrodes exhibited good selectivity for PPA.Cl with respect to a large number of inorganic cations, sugars, amino acids, and components other than Phenylpropanolamine of the mixed drugs. The effect of temperature on the electrodes was also studied.
Robert S. Hoffman - One of the best experts on this subject based on the ideXlab platform.
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Methemoglobinemia: an occupational hazard of Phenylpropanolamine production.
Clinical Toxicology, 2008Co-Authors: Robert S. HoffmanAbstract:Two workers from the same factory presented to the same emergency department within six weeks of one another with moderate (Case 1) and severe (Case 2) methemoglobinemia. Subsequent investigation revealed that the factory produces Phenylpropanolamine and that both patients, shortly before becoming ill, were inadvertently exposed to methyl nitrite, a critical reagent in this production. Although other nitrites induce methemoglobinemia, exposure to methyl nitrite during Phenylpropanolamine production appears to be a new cause of occupational methemoglobinemia.
