The Experts below are selected from a list of 3789 Experts worldwide ranked by ideXlab platform
Frederick X. Gibbons - One of the best experts on this subject based on the ideXlab platform.
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effects of Photoaging information and uv photo on sun protection intentions and behaviours a cross regional comparison
Psychology & Health, 2013Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Frederick X. GibbonsAbstract:There is limited empirical evidence regarding differences in sun protection practices in different regions of the USA. This study examined whether there are regional differences in the efficacy of exposure to UV photographs and Photoaging information (e.g. wrinkles and age spots) for increasing sun protection behaviours. Students attending a public university in either the Midwestern (Iowa) or Southwestern (Southern California) US reported baseline sun exposure and protection practices and were then randomly assigned to either receive information about Photoaging, have a UV photo taken, both receive Photoaging information and have a UV photo taken, or to receive neither intervention. Sun protection intentions were assessed immediately after the interventions, and both self-reported sun protection behaviours and an objective assessment (via spectrophotometry) of skin colour change were measured at the end of summer and one year following the interventions. The results showed a pervasive pattern of more ris...
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Effects of upward and downward social comparison information on the efficacy of an appearance-based sun protection intervention: a randomized, controlled experiment
Journal of behavioral medicine, 2010Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Frederick X. GibbonsAbstract:This experiment examined the impact of adding upward and/or downward social comparison information on the efficacy of an appearance-based sun protection intervention (UV photos and Photoaging information). Southern California college students (N = 126) were randomly assigned to one of four conditions: control, intervention, intervention plus upward social comparison, intervention plus downward social comparison. The results demonstrated that all those who received the basic UV photo/Photoaging intervention reported greater perceived susceptibility to Photoaging (d = .74), less favorable tanning cognitions (d = .44), and greater intentions to sun protect (d = 1.32) relative to controls. Of more interest, while the basic intervention increased sun protective behavior during the subsequent 5 weeks relative to controls (d = .44), the addition of downward comparison information completely negated this benefit. Upward comparison information produced sun protection levels that were only slightly (and nonsignificantly) greater than in the basic intervention condition and, as such, does not appear to be a cost-effective addition. Possible mechanisms that may have reduced the benefits of upward comparison information and contributed to the undermining effects of downward comparison information are discussed.
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social norms information enhances the efficacy of an appearance based sun protection intervention
Social Science & Medicine, 2008Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Heather A Butler, Frederick X. GibbonsAbstract:This experiment examined whether the efficacy of an appearance-based sun protection intervention could be enhanced by the addition of social norms information. Southern California college students (N=125, predominantly female) were randomly assigned to either an appearance-based sun protection intervention that consisted of a photograph depicting underlying sun damage to their skin (UV photo) and information about Photoaging or to a control condition. Those assigned to the intervention were further randomized to receive information about what one should do to prevent Photoaging (injunctive norms information), information about the number of their peers who currently use regular sun protection (descriptive norms information), both injunctive and descriptive norms information, or neither type of norms information. The results demonstrated that those who received the UV photo/Photoaging information intervention expressed greater sun protection intentions and subsequently reported greater sun protection behaviors than did controls. Further, the addition of both injunctive and descriptive norms information increased self-reported sun protection behaviors during the subsequent month.
Heike I. M. Mahler - One of the best experts on this subject based on the ideXlab platform.
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effects of Photoaging information and uv photo on sun protection intentions and behaviours a cross regional comparison
Psychology & Health, 2013Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Frederick X. GibbonsAbstract:There is limited empirical evidence regarding differences in sun protection practices in different regions of the USA. This study examined whether there are regional differences in the efficacy of exposure to UV photographs and Photoaging information (e.g. wrinkles and age spots) for increasing sun protection behaviours. Students attending a public university in either the Midwestern (Iowa) or Southwestern (Southern California) US reported baseline sun exposure and protection practices and were then randomly assigned to either receive information about Photoaging, have a UV photo taken, both receive Photoaging information and have a UV photo taken, or to receive neither intervention. Sun protection intentions were assessed immediately after the interventions, and both self-reported sun protection behaviours and an objective assessment (via spectrophotometry) of skin colour change were measured at the end of summer and one year following the interventions. The results showed a pervasive pattern of more ris...
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Effects of upward and downward social comparison information on the efficacy of an appearance-based sun protection intervention: a randomized, controlled experiment
Journal of behavioral medicine, 2010Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Frederick X. GibbonsAbstract:This experiment examined the impact of adding upward and/or downward social comparison information on the efficacy of an appearance-based sun protection intervention (UV photos and Photoaging information). Southern California college students (N = 126) were randomly assigned to one of four conditions: control, intervention, intervention plus upward social comparison, intervention plus downward social comparison. The results demonstrated that all those who received the basic UV photo/Photoaging intervention reported greater perceived susceptibility to Photoaging (d = .74), less favorable tanning cognitions (d = .44), and greater intentions to sun protect (d = 1.32) relative to controls. Of more interest, while the basic intervention increased sun protective behavior during the subsequent 5 weeks relative to controls (d = .44), the addition of downward comparison information completely negated this benefit. Upward comparison information produced sun protection levels that were only slightly (and nonsignificantly) greater than in the basic intervention condition and, as such, does not appear to be a cost-effective addition. Possible mechanisms that may have reduced the benefits of upward comparison information and contributed to the undermining effects of downward comparison information are discussed.
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social norms information enhances the efficacy of an appearance based sun protection intervention
Social Science & Medicine, 2008Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Heather A Butler, Frederick X. GibbonsAbstract:This experiment examined whether the efficacy of an appearance-based sun protection intervention could be enhanced by the addition of social norms information. Southern California college students (N=125, predominantly female) were randomly assigned to either an appearance-based sun protection intervention that consisted of a photograph depicting underlying sun damage to their skin (UV photo) and information about Photoaging or to a control condition. Those assigned to the intervention were further randomized to receive information about what one should do to prevent Photoaging (injunctive norms information), information about the number of their peers who currently use regular sun protection (descriptive norms information), both injunctive and descriptive norms information, or neither type of norms information. The results demonstrated that those who received the UV photo/Photoaging information intervention expressed greater sun protection intentions and subsequently reported greater sun protection behaviors than did controls. Further, the addition of both injunctive and descriptive norms information increased self-reported sun protection behaviors during the subsequent month.
Hongduo Chen - One of the best experts on this subject based on the ideXlab platform.
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kanglaite attenuates uvb induced down regulation of aquaporin 3 in cultured human skin keratinocytes
International Journal of Molecular Medicine, 2012Co-Authors: Shijun Shan, John Z.s. Chen, Ting Xiao, Shiling Geng, Yuxiao Hong, Ying Guo, Huachen Wei, Wei Liu, Hongduo ChenAbstract:Ultraviolet (UV) radiation plays an important role in the pathogenesis of skin Photoaging. Depending on the wavelength of UV, the epidermis is affected primarily by UVB. One major characteristic of Photoaging is the dehydration of the skin. Membrane-inserted water channels (aquaporins) are involved in this process. In this study we demonstrated that UVB radiation induced aquaporin-3 (AQP3) down-regulation in cultured human skin keratinocytes. Kanglaite is a mixture consisting of extractions of Coix Seed, which is an effective anti-neoplastic agent and can inhibit the activities of protein kinase C and NF-κB. We demonstrated that Kanglaite inhibited UVB-induced AQP3 down-regulation of cultured human skin keratinocytes. Our findings provide a potential new agent for anti-Photoaging. The related molecular mechanisms remain to be further elucidated.
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a split face study of intense pulsed light on Photoaging skin in chinese population
Lasers in Surgery and Medicine, 2010Co-Authors: Yuanhong Li, Guanghui Dong, Yan Wu, John Z.s. Chen, Yuanyuan Xu, Jing Chen, Hongduo ChenAbstract:Background and Objectives: Intense pulsed light (IPL) is regarded as the gold standard of nonablative photorejuvenation. Yet there is still a need to observe its efficacy and safety on dark skin using a split-face module. Study Design/Materials and Methods: Twenty-four Chinese women with Photoaging were enrolled in this study. Patients were randomized to receive four IPL treatments at 3- to 4-week intervals on one side of face, with the other side spared as control. Changes of Photoaging were evaluated using a global evaluation, an overall self-assessment, a Mexameter and a Corneometer. Skin biopsies were taken after four sessions of treatment on one side of face. The melanocyte density and the contents of melanin, collagen fibers, and elastic fibers were stained and used to evaluate the improvement on dyschromia and other signs of Photoaging. Results: The global scores of Photoaging on treated side decreased significantly from 3.02 to 1.22, while it remained unchanged on the untreated side. Twenty-one of 24 patients (87.5%) rated their improvement as excellent or good. The difference on the values of melanin index and erythema index on treated side were significantly larger than those on untreated side after the 1st session, the 4th session and at 3-month follow-up (P<0.05). The melanin contents were significantly decreased and the collagen fibers were obviously increased only on treated side (P<0.05). Adverse effects of treated side were limited to mild pain and transient erythema. Conclusion: Using this split-face module, IPL treatment is proved both clinically and histologically to be effective in treating Photoaging skin in Chinese population. Adverse effects were minimal and acceptable. Lasers Surg. Med. 42:185–191, 2010. 2010 Wiley-Liss, Inc.
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application of a new intense pulsed light device in the treatment of Photoaging skin in asian patients
Dermatologic Surgery, 2008Co-Authors: Yuanhong Li, Guanghui Dong, Yan Wu, John Z.s. Chen, Hongduo ChenAbstract:BACKGROUND Intense pulsed light (IPL) technology has long been used in the treatment of Photoaging skin. OBJECTIVE To evaluate the efficacy and safety of a new IPL device in the treatment of Photoaging skin in Asian patients. METHODS One hundred fifty-two Chinese women with Photoaging skin were enrolled in this open-labeled study. Subjects received four IPL treatments at 3- to 4-week intervals. Changes of Photoaging were evaluated using a global evaluation, an overall self-assessment, a Mexameter, and a Corneometer. RESULTS One hundred thirty-nine of 152 patients (91.44%) experienced a score decrease of 3 or 2 grades, according to the dermatologist. One hundred thirty-six of 152 patients (89.47%) rated their overall improvement as excellent or good. The mean skin melanin index (MI) and erythema index values deceased with each session. MI on forehead and EI on cheilion decreased most significantly. Adverse effects were limited to mild pain and transient erythema. CONCLUSION IPL treatment is a safe and effective method for Photoaging skin in Asian patients. Adverse effects were minimal and acceptable.
Tommaso Iannitti - One of the best experts on this subject based on the ideXlab platform.
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a dietary supplement improves facial Photoaging and skin sebum hydration and tonicity modulating serum fibronectin neutrophil elastase 2 hyaluronic acid and carbonylated proteins
Journal of Photochemistry and Photobiology B-biology, 2015Co-Authors: Alessandro Di Cerbo, Beniamino Palmieri, Carmen Laurino, Tommaso IannittiAbstract:Abstract Background and aims Excessive exposure to the sun can cause severe Photoaging as early as the second decade of life resulting in a loss of physiological elastic fiber functions. We designed a first study to assess differences in facial skin pH, sebum, elasticity, hydration and tonicity and serum levels of fibronectin, elastin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins between patients affected by facial Photoaging and healthy controls. In a second study we tested the hypothesis that a dietary supplement would improve facial Photoaging, also promoting changes in the above mentioned skin and serum parameters. Methods In the first study we enrolled 30 women [age: 47.5 ± 1.6 years (mean ± standard error of the mean)] affected by moderate facial Photoaging (4 cm ≤ Visual Analogue Scale (VAS) n = 22) and severe (VAS ≥ 7 cm; n = 8) facial Photoaging, who were randomized to receive a pharmaceutical formulation (VISCODERM® Pearls; IBSA FARMACEUTICI ITALIA Srl, Lodi, Italy) containing Pycnogenol®, collagen, coenzyme Q10, low-molecular-weight hyaluronic acid, chondroitin sulfate and glucosamine sulfate ( n = 15) or placebo ( n = 15). Dietary supplement and placebo were administered 2 times a day for 4 weeks. Facial Photoaging was assessed by VAS in the first cohort of patients affected by facial Photoaging and healthy controls and, at baseline and 2 weeks after the end of treatment, in the second cohort of patients who underwent treatment with VISCODERM® Pearls and placebo. Skin Tester was used to analyze differences in facial skin parameters between patients affected by facial Photoaging and healthy controls. Skin Tester was also used to assess the effect of VISCODERM® Pearls on facial skin parameters and compared with placebo 2 weeks after the end of treatment. Serum levels of fibronectin, elastin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins were measured by enzyme-linked immunosorbent assay in the first cohort of patients affected by facial Photoaging and healthy controls and, at baseline and 2 weeks after the end of treatment, in the second cohort of patients who underwent treatment with VISCODERM® Pearls and placebo. Results VAS Photoaging score was higher in patients affected by Photoaging, if compared with healthy controls ( p p p p p p p p p p p p p p p Conclusions We found significantly increased serum levels of neutrophil elastase 2, elastin and carbonylated proteins and decreased levels of hyaluronic acid and fibronectin in patients affected by facial Photoaging, if compared with healthy controls. These findings coupled with a significant decrease in skin hydration, tonicity and elasticity and increased skin pH and sebum. Treatment with the dietary supplement VISCODERM® Pearls significantly improved VAS Photoaging score and skin hydration, sebum and tonicity 2 weeks after the end of a 4-week treatment period in patients affected by moderate to severe facial Photoaging. These findings coupled with a significant increase in serum fibronectin and hyaluronic acid and a decrease in serum carbonylated proteins and neutrophil elastase 2 in the active treatment group, if compared with placebo. Our findings suggest that VISCODERM® Pearls is effective for treatment of facial Photoaging but further studies in larger cohorts of patients are required.
James A. Kulik - One of the best experts on this subject based on the ideXlab platform.
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effects of Photoaging information and uv photo on sun protection intentions and behaviours a cross regional comparison
Psychology & Health, 2013Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Frederick X. GibbonsAbstract:There is limited empirical evidence regarding differences in sun protection practices in different regions of the USA. This study examined whether there are regional differences in the efficacy of exposure to UV photographs and Photoaging information (e.g. wrinkles and age spots) for increasing sun protection behaviours. Students attending a public university in either the Midwestern (Iowa) or Southwestern (Southern California) US reported baseline sun exposure and protection practices and were then randomly assigned to either receive information about Photoaging, have a UV photo taken, both receive Photoaging information and have a UV photo taken, or to receive neither intervention. Sun protection intentions were assessed immediately after the interventions, and both self-reported sun protection behaviours and an objective assessment (via spectrophotometry) of skin colour change were measured at the end of summer and one year following the interventions. The results showed a pervasive pattern of more ris...
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Effects of upward and downward social comparison information on the efficacy of an appearance-based sun protection intervention: a randomized, controlled experiment
Journal of behavioral medicine, 2010Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Frederick X. GibbonsAbstract:This experiment examined the impact of adding upward and/or downward social comparison information on the efficacy of an appearance-based sun protection intervention (UV photos and Photoaging information). Southern California college students (N = 126) were randomly assigned to one of four conditions: control, intervention, intervention plus upward social comparison, intervention plus downward social comparison. The results demonstrated that all those who received the basic UV photo/Photoaging intervention reported greater perceived susceptibility to Photoaging (d = .74), less favorable tanning cognitions (d = .44), and greater intentions to sun protect (d = 1.32) relative to controls. Of more interest, while the basic intervention increased sun protective behavior during the subsequent 5 weeks relative to controls (d = .44), the addition of downward comparison information completely negated this benefit. Upward comparison information produced sun protection levels that were only slightly (and nonsignificantly) greater than in the basic intervention condition and, as such, does not appear to be a cost-effective addition. Possible mechanisms that may have reduced the benefits of upward comparison information and contributed to the undermining effects of downward comparison information are discussed.
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social norms information enhances the efficacy of an appearance based sun protection intervention
Social Science & Medicine, 2008Co-Authors: Heike I. M. Mahler, Meg Gerrard, James A. Kulik, Heather A Butler, Frederick X. GibbonsAbstract:This experiment examined whether the efficacy of an appearance-based sun protection intervention could be enhanced by the addition of social norms information. Southern California college students (N=125, predominantly female) were randomly assigned to either an appearance-based sun protection intervention that consisted of a photograph depicting underlying sun damage to their skin (UV photo) and information about Photoaging or to a control condition. Those assigned to the intervention were further randomized to receive information about what one should do to prevent Photoaging (injunctive norms information), information about the number of their peers who currently use regular sun protection (descriptive norms information), both injunctive and descriptive norms information, or neither type of norms information. The results demonstrated that those who received the UV photo/Photoaging information intervention expressed greater sun protection intentions and subsequently reported greater sun protection behaviors than did controls. Further, the addition of both injunctive and descriptive norms information increased self-reported sun protection behaviors during the subsequent month.
