The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
Yoshihisa Urita - One of the best experts on this subject based on the ideXlab platform.
-
usefulness of gastric cancer screening using the serum pepsinogen test method
The American Journal of Gastroenterology, 2003Co-Authors: Kazumasa Miki, Masuo Morita, Masahiko Sasajima, Reiko Hoshina, Eiko Kanda, Yoshihisa UritaAbstract:Abstract Objective The measurement of serum pepsinogen has recently gained attention as a candidate for a new screening test for gastric cancer. This method is particularly attractive given its lower cost and simplicity to administer relative to Photofluorography. To compare the accuracy between the two screening methods, and to elucidate the usefulness of the serum pepsinogen test method, we performed this study. Methods Mass screening for gastric cancer was performed using both the x-ray and pepsinogen test methods simultaneously on 286 company employees. The number of tests conducted was 5567 in total. The mean age was 48 yr in both men and women. Informed consent was taken individually. Fasting blood samples were collected, and measurement of the serum pepsinogen concentration was carried out by immunoradiometric assay. Results The percentage of those screened, who needed further examination was 11.7% for the x-ray method and 23.6% for the pepsinogen test method. The percentage of those who required further investigation, as the second step of screening, using endoscopy, was 55.4% for the x-ray method and 51.9% for the pepsinogen test method, respectively. Ten gastric cancers were detected in total. The incidence was 0.05% in the x-ray method and 0.18% in the pepsinogen test method. The rate of early gastric cancer to advanced gastric cancer was 9 to 1, that is, 90% were in the early stages. The positive predictive value was 0.8% in the x-ray method and 1.4% in the pepsinogen test method. Conclusions The pepsinogen test method can be used as a screening test for high-risk subjects with atrophic gastritis, rather than as a tool for cancer itself. Systemic endoscopic surveillance of this group is also useful.
E A Mumcuoglu - One of the best experts on this subject based on the ideXlab platform.
-
does 100 mm Photofluorography always have a dose advantage over conventional film screen radiography in barium meals
British Journal of Radiology, 1997Co-Authors: A S K Dzikjurasz, E A MumcuogluAbstract:It is generally held that 100 mm Photofluorography has a significant dose saving advantage over conventional radiography. The dose area product (DAP) data for the two formats were available for study in consecutive patients undergoing barium meal examination. There was no significant difference in DAP readings between the two formats. Conventional radiographs expose a 40% greater area than the 100 mm format, probably accounting for the lower mean DAP value of Photofluorography. The mean DAP for whole examinations was 26.1 Gy cm2 for Photofluorography, and 30.5 Gy cm2 for conventional radiography. These are both above the third quartile of national reference dose levels. There is little apparent difference in the doses incurred by patients between the two formats in respect of the working practice of the department. Barium meals will therefore continue to be recorded on both formats.
Walter J Russell - One of the best experts on this subject based on the ideXlab platform.
-
organ doses to atomic bomb survivors during Photofluorography fluoroscopy and computed tomography
British Journal of Radiology, 1991Co-Authors: Kazuo Kato, Shigetoshi Antoku, Shozo Sawada, Takuro Wada, Walter J RussellAbstract:Abstract Doses to the salivary glands, thyroid gland, breast, lung, stomach and colon during mass radiological gastric screening, mass radiographic chest screening, upper gastrointestinal series and computed tomography were determined by exposing a female human phantom to simulated radiological X-ray examinations as performed in community hospitals. The doses were measured using thermoluminescent dosemeters, and the results will be used to document organ doses received by participants in the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation Adult Health Study.
Kazumasa Miki - One of the best experts on this subject based on the ideXlab platform.
-
usefulness of gastric cancer screening using the serum pepsinogen test method
The American Journal of Gastroenterology, 2003Co-Authors: Kazumasa Miki, Masuo Morita, Masahiko Sasajima, Reiko Hoshina, Eiko Kanda, Yoshihisa UritaAbstract:Abstract Objective The measurement of serum pepsinogen has recently gained attention as a candidate for a new screening test for gastric cancer. This method is particularly attractive given its lower cost and simplicity to administer relative to Photofluorography. To compare the accuracy between the two screening methods, and to elucidate the usefulness of the serum pepsinogen test method, we performed this study. Methods Mass screening for gastric cancer was performed using both the x-ray and pepsinogen test methods simultaneously on 286 company employees. The number of tests conducted was 5567 in total. The mean age was 48 yr in both men and women. Informed consent was taken individually. Fasting blood samples were collected, and measurement of the serum pepsinogen concentration was carried out by immunoradiometric assay. Results The percentage of those screened, who needed further examination was 11.7% for the x-ray method and 23.6% for the pepsinogen test method. The percentage of those who required further investigation, as the second step of screening, using endoscopy, was 55.4% for the x-ray method and 51.9% for the pepsinogen test method, respectively. Ten gastric cancers were detected in total. The incidence was 0.05% in the x-ray method and 0.18% in the pepsinogen test method. The rate of early gastric cancer to advanced gastric cancer was 9 to 1, that is, 90% were in the early stages. The positive predictive value was 0.8% in the x-ray method and 1.4% in the pepsinogen test method. Conclusions The pepsinogen test method can be used as a screening test for high-risk subjects with atrophic gastritis, rather than as a tool for cancer itself. Systemic endoscopic surveillance of this group is also useful.
A S K Dzikjurasz - One of the best experts on this subject based on the ideXlab platform.
-
does 100 mm Photofluorography always have a dose advantage over conventional film screen radiography in barium meals
British Journal of Radiology, 1997Co-Authors: A S K Dzikjurasz, E A MumcuogluAbstract:It is generally held that 100 mm Photofluorography has a significant dose saving advantage over conventional radiography. The dose area product (DAP) data for the two formats were available for study in consecutive patients undergoing barium meal examination. There was no significant difference in DAP readings between the two formats. Conventional radiographs expose a 40% greater area than the 100 mm format, probably accounting for the lower mean DAP value of Photofluorography. The mean DAP for whole examinations was 26.1 Gy cm2 for Photofluorography, and 30.5 Gy cm2 for conventional radiography. These are both above the third quartile of national reference dose levels. There is little apparent difference in the doses incurred by patients between the two formats in respect of the working practice of the department. Barium meals will therefore continue to be recorded on both formats.