The Experts below are selected from a list of 645 Experts worldwide ranked by ideXlab platform
Tamotsu Matsuda - One of the best experts on this subject based on the ideXlab platform.
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pulmonary Plasma Cell Granuloma improves with corticosteroid therapy
Chest, 1994Co-Authors: Takurna Bando, Masaki Fujimura, Yatsugi Noda, Jinichiro Hirose, Goroku Ohta, Tamotsu MatsudaAbstract:Two cases of pulmonary Plasma Cell Granuloma that progressed after respiratory infectious disease are described. The men, 48 and 32 years old, were admitted to the hospital with blood-streaked sputum and mass or nodular shadow on chest radiograph. Close examination revealed that these tumors were Plasma Cell Granulomas, which are known as postinflammatory pseudotumors. Biopsy specimens, obtained by way of transbronchial biopsy, demonstrated proliferation of mature Plasma Cells and infiltration of lymphocytes supported by granulation tissue, and there was no evidence of malignancy or tuberculosis. Although surgery is common in the treatment of pulmonary Plasma Cell Granuloma, some cases relapse or invade the mediastinum. Therefore, we decided to treat these patients with prednisolone, 30 mg/d, an anti-inflammatory and immunosuppressive agent. Two or 4 weeks later, these tumors disappeared completely and they have never recurred. As middle-dosage corticosteroid therapy is not cytotoxic, it is useful for the treatment of pulmonary Plasma Cell Granuloma, especially in multifocal, unresectable, and/or relapsing cases.
Takurna Bando - One of the best experts on this subject based on the ideXlab platform.
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pulmonary Plasma Cell Granuloma improves with corticosteroid therapy
Chest, 1994Co-Authors: Takurna Bando, Masaki Fujimura, Yatsugi Noda, Jinichiro Hirose, Goroku Ohta, Tamotsu MatsudaAbstract:Two cases of pulmonary Plasma Cell Granuloma that progressed after respiratory infectious disease are described. The men, 48 and 32 years old, were admitted to the hospital with blood-streaked sputum and mass or nodular shadow on chest radiograph. Close examination revealed that these tumors were Plasma Cell Granulomas, which are known as postinflammatory pseudotumors. Biopsy specimens, obtained by way of transbronchial biopsy, demonstrated proliferation of mature Plasma Cells and infiltration of lymphocytes supported by granulation tissue, and there was no evidence of malignancy or tuberculosis. Although surgery is common in the treatment of pulmonary Plasma Cell Granuloma, some cases relapse or invade the mediastinum. Therefore, we decided to treat these patients with prednisolone, 30 mg/d, an anti-inflammatory and immunosuppressive agent. Two or 4 weeks later, these tumors disappeared completely and they have never recurred. As middle-dosage corticosteroid therapy is not cytotoxic, it is useful for the treatment of pulmonary Plasma Cell Granuloma, especially in multifocal, unresectable, and/or relapsing cases.
Chingnan Lin - One of the best experts on this subject based on the ideXlab platform.
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multicentric Plasma Cell Granuloma of spinal cord meninges
Clinical Orthopaedics and Related Research, 1995Co-Authors: Pochin Hsieh, Chingnan LinAbstract:A 37-year-old man had multicentric meningeal Plasma Cell Granuloma of the spinal cord. The presenting symptoms were back pain and progressive numbness and weakness of both legs for 6 months. Through physical examination, hypoesthesia below the inguinal region and decreased muscle power of both legs with bilateral ankle clonus was seen. Computed tomographic myelogram and magnetic resonance imaging showed 2 extramedullary intradural masses at the T5 and T12-L1 levels. The latter produced all the neurologic deficits. The patient underwent 2 consecutive operations : laminectomy with removal of the tumor at the T12-L1 level, and thoracotomy with partial corpectomy and removal of the tumor at T5 level. Findings from both operations showed that the tumors arose from the dura and grew inward compressing the spinal cord. Microscopically, these 2 tumors showed identical pictures of Plasma Cell Granuloma and were characterized by numerous Granulomas formed by mature Plasma Cells with Russell bodies and histiocytes set in a fibrotic background. The patient was discharged with complete recovery of sensory and motor functions of both legs.
Turhan Okten - One of the best experts on this subject based on the ideXlab platform.
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Plasma Cell Granuloma of the thyroid
Apmis, 2008Co-Authors: Kemal Deniz, Tahir E Patiroglu, Turhan OktenAbstract:We report two cases of thyroidal Plasma Cell Granuloma. Both patients underwent surgical resection after presenting with painless neck swelling. Histopathologic examination of the specimens revealed Plasmacytes infiltrating the thyroid parenchyma and immunohistochemical studies showed the polyclonal nature of the Plasma Cells. Plasma Cell Granuloma is a benign lesion and its appearance in the thyroid gland is extremely rare. Eleven prior cases with thyroid localization have been reported to date in the English literature. Nine of the Plasma Cell Granuloma cases occurred in women, four in men (including the present cases). The clinicopathologic features and diagnostic difficulties of this rare entity are described, and its relation to inflammatory pseudotumor of other sites is discussed with a review of the literature.
Chan Ii Park - One of the best experts on this subject based on the ideXlab platform.
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Plasma Cell Granuloma of the temporal bone a case report
Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 1994Co-Authors: Boo Hyun Nam, Ki Sang Rha, Jang Yuorl Yoo, Chan Ii ParkAbstract:Background. Plasma Cell Granuloma is a rare benign lesion which is found most frequently in the lungs, and a few cases have been described in the head and neck. In the middle ear and mastoid, a case of Plasma Cell Granuloma was reported by Benton et al. Methods and Results. A 24-year-old woman was seen with a 7-month history of otalgia and decreased hearing. A computed tomographic (CT) scan showed a soft tissue mass occupying most of the mastoid bone. The mass and the contiguous dura were enhanced homogeneously on magnetic resonance imaging (MRI) scan. Microscopic examination showed Plasma Cell aggregates mixed with other inflammatory Cells and Russell's bodies in a fibrous stroma. Immunoperoxidase studies revealed intracytoplasmic kappa and lambda light chains, and the lesion was confirmed as nonneoplastic and of polyclonal origin (ie, Plasma Cell Granuloma). The patient was treated with conservative surgical excision (a canal-down mastoidectomy) and postoperative radiotherapy (5,040 cGy in 28 fractions) and remains free of disease 1 year after treatment. Conclusions. A case of Plasma Cell Granuloma is reported, and we believe this is the second case report of Plasma Cell Granuloma affecting the temporal bone. © 1994 John Wiley & Sons, Inc.