The Experts below are selected from a list of 30 Experts worldwide ranked by ideXlab platform
Gülistan Köksal - One of the best experts on this subject based on the ideXlab platform.
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Thyroid Metastasis from small cell lung carcinoma: a case report and review of the literature
Journal of medical case reports, 2015Co-Authors: Ahmet Selçuk Can, Gülistan KöksalAbstract:Introduction Small cell lung carcinoma frequently metastasizes to lymph nodes, liver, adrenal glands, bone, brain and Pleura. Metastasis of small cell lung cancer to the thyroid gland is extremely rare.
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Thyroid Metastasis from small cell lung carcinoma: a case report and review of the literature
Journal of Medical Case Reports, 2015Co-Authors: Ahmet Selçuk Can, Gülistan KöksalAbstract:Introduction Small cell lung carcinoma frequently metastasizes to lymph nodes, liver, adrenal glands, bone, brain and Pleura. Metastasis of small cell lung cancer to the thyroid gland is extremely rare. Case presentation A 55-year-old Turkish man presented with a mediastinal mass intermingled with mediastinal lymphadenopathy, measuring 11cm in total, and encasing superior vena cava and deviating his trachea, esophagus and vascular structures. He had superior vena cava syndrome. His thyroid appeared normal on computed tomography of his chest. A bronchoscopic biopsy showed small cell lung carcinoma. Chemotherapy with cisplatin and etoposide and external radiotherapy was given. Six months after the presentation, multiple brain metastases were detected on magnetic resonance imaging. Chemotherapy was changed to topotecan and cranial irradiation was performed. At the same time, a right thyroid nodule was detected on computed tomography of his chest and showed growth in size in the following 4 months. A palpable right thyroid nodule came to our attention at that time, the 10th month of presentation. Free thyroxine, free triiodothyronine, thyroid-stimulating hormone, antithyroglobulin and antithyroid peroxidase antibodies were within normal limits. Thyroid ultrasonography showed a right thyroid lobe 26.2×16.8×15.7mm hypoechoic solid nodule with irregular borders. Ultrasonography-guided thyroid fine-needle aspiration biopsy showed Metastasis from small cell lung carcinoma. His cranial metastases worsened. He developed right cervical lymph node, hepatic, pancreatic and meningeal metastases and died 15 months after the initial presentation and 9 months after the detection of thyroid Metastasis by computed tomography of his chest. Our case and two previously reported cases were male, 55-years old or older and had history of more than 40 pack-years of cigarette smoking. All had metastatic disease elsewhere, when the thyroid Metastasis was diagnosed by fine-needle aspiration biopsy. All had poor survival, between 9 and 18 months, after thyroid Metastasis was diagnosed. Conclusions We conclude that in a patient with a known history of malignant disease, the finding of a new thyroid mass should be promptly evaluated with a thyroid fine-needle aspiration biopsy to search for metastatic disease. The clinical features of our and two previously reported cases were summarized.
Ahmet Selçuk Can - One of the best experts on this subject based on the ideXlab platform.
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Thyroid Metastasis from small cell lung carcinoma: a case report and review of the literature
Journal of medical case reports, 2015Co-Authors: Ahmet Selçuk Can, Gülistan KöksalAbstract:Introduction Small cell lung carcinoma frequently metastasizes to lymph nodes, liver, adrenal glands, bone, brain and Pleura. Metastasis of small cell lung cancer to the thyroid gland is extremely rare.
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Thyroid Metastasis from small cell lung carcinoma: a case report and review of the literature
Journal of Medical Case Reports, 2015Co-Authors: Ahmet Selçuk Can, Gülistan KöksalAbstract:Introduction Small cell lung carcinoma frequently metastasizes to lymph nodes, liver, adrenal glands, bone, brain and Pleura. Metastasis of small cell lung cancer to the thyroid gland is extremely rare. Case presentation A 55-year-old Turkish man presented with a mediastinal mass intermingled with mediastinal lymphadenopathy, measuring 11cm in total, and encasing superior vena cava and deviating his trachea, esophagus and vascular structures. He had superior vena cava syndrome. His thyroid appeared normal on computed tomography of his chest. A bronchoscopic biopsy showed small cell lung carcinoma. Chemotherapy with cisplatin and etoposide and external radiotherapy was given. Six months after the presentation, multiple brain metastases were detected on magnetic resonance imaging. Chemotherapy was changed to topotecan and cranial irradiation was performed. At the same time, a right thyroid nodule was detected on computed tomography of his chest and showed growth in size in the following 4 months. A palpable right thyroid nodule came to our attention at that time, the 10th month of presentation. Free thyroxine, free triiodothyronine, thyroid-stimulating hormone, antithyroglobulin and antithyroid peroxidase antibodies were within normal limits. Thyroid ultrasonography showed a right thyroid lobe 26.2×16.8×15.7mm hypoechoic solid nodule with irregular borders. Ultrasonography-guided thyroid fine-needle aspiration biopsy showed Metastasis from small cell lung carcinoma. His cranial metastases worsened. He developed right cervical lymph node, hepatic, pancreatic and meningeal metastases and died 15 months after the initial presentation and 9 months after the detection of thyroid Metastasis by computed tomography of his chest. Our case and two previously reported cases were male, 55-years old or older and had history of more than 40 pack-years of cigarette smoking. All had metastatic disease elsewhere, when the thyroid Metastasis was diagnosed by fine-needle aspiration biopsy. All had poor survival, between 9 and 18 months, after thyroid Metastasis was diagnosed. Conclusions We conclude that in a patient with a known history of malignant disease, the finding of a new thyroid mass should be promptly evaluated with a thyroid fine-needle aspiration biopsy to search for metastatic disease. The clinical features of our and two previously reported cases were summarized.
Bao Yong-xing - One of the best experts on this subject based on the ideXlab platform.
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Clinical application of CT-guided biopsy in thoracic tumor
Journal of Xinjiang Medical University, 2004Co-Authors: Bao Yong-xingAbstract:Objective: To probe the value of clinical application of CT-guided biopsy in thoracic tumor. Methods: Thirty-two patients with thoracic tumor were reviewad between Match, 2001-April, 2003. There were 8 cases with peripheral mass of lung, 20 with central and mediastinal mass, and 4 with Pleura Metastasis. Among them, 16 patients had undergone bronchoscopy but without pathological result. After CT positioning, 16-18G BARD puncturable gun were used to penetrate anterior or posterior chest wall and kept clear of important organs. Histology and cytology detection were done after 1-3 times puncture. Results: Twenty-eight cases were diagnosed definitely with positive rate 81.82%(28/32). 1 case with peumothorax ; two with a little bit bleeding; no other serious complications. Conclusion: CT-guided biopsy deserved to further study, especially in patients without positive result of bronchoscopy.
Jean Lemaitre - One of the best experts on this subject based on the ideXlab platform.
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Acute appendicitis as an unusual cause of invasive ductal breast carcinoma Metastasis.
Journal of surgical case reports, 2020Co-Authors: Vincent De Pauw, Julie Navez, Stéphane Holbrechts, Jean LemaitreAbstract:Acute appendicitis is one of the most common causes of abdominal pain at the emergency room. In rare cases, it can be caused by malignancy, even metastatic lesions from extra-abdominal neoplasia. Herein, we report a case of a 64-year-old female with a history of invasive ductal carcinoma of the breast treated by chemotherapy, surgery, radiotherapy and hormonotherapy, relapsing several years later as a bone and a Pleura Metastasis successfully cured by locoregional therapy and hormonal treatment. She presented with acute abdominal pain without signs of peritonitis. Abdominal computed tomodensitometry showed sign of appendicitis. Therefore, laparoscopic exploration and appendicectomy was performed. During surgery, multiple peritoneal nodules were found and harvested. Pathology showed metastatic nodules of invasive ductal breast carcinoma, including in the appendicular wall, concluding to peritoneal carcinomatosis. The postoperative course was uneventful, but the patient died 1 year later after refusing anticancer treatment.
Wei Shu-fang - One of the best experts on this subject based on the ideXlab platform.
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Differential value of flexirigid thorascopy in Pleural effusions
Journal of Clinical Pulmonary Medicine, 2009Co-Authors: Wei Shu-fangAbstract:Objective To evaluate the use of flexirigid thorascopy for benign and malignant Pleural effusion.Methods 92 patients with difficult Pleural effusion were diagnosed through flexirigid thorascopy Pleural biopsy under local anesthesia.Results 87 patients were diagnosed by pathological analysis,and the positive rate was 94.5% (87/92). The diagnosis of 87 cases were malignant Pleura effusions in 46.7% (43/92),Pleura Metastasis lung cancer in 39 cases,adenocarcinoma in 28 cases,Pleura mesothelioma in 1 case,another Metastasis carcinoma in 3 cases and 47.8% (44.92) of benign Pleural effusion,tuberculosis pleurisy in 37 cases,chronic inflammation in 6 cases and hepatic hydrothorax in 1 case,only 5.4% (5/92) cases had no problem to be found. Thorascopy of Metastasis carcinoma showed differential diagnosis from tuberculosis pleurisy. No serious complication occurred in all cases.Conclusion Medical thorascopy is safe,simple,and has high positive rate and has very important value in the diagnosis of differential Pleural effusion.