The Experts below are selected from a list of 300 Experts worldwide ranked by ideXlab platform

Lanqun Mao - One of the best experts on this subject based on the ideXlab platform.

  • Strong interaction between imidazolium-based Polycationic Polymer and ferricyanide: toward redox potential regulation for selective in vivo electrochemical measurements.
    Analytical chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)(6)(3-)) and ferrocyanide (Fe(CN)(6)(4-)) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)(6)(3-/4-), imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)(6)(3-/4-) due to its stronger interaction with Fe(CN)(6)(3-) than with Fe(CN)(6)(4-). The different adsorption ability of Fe(CN)(6)(3-) and Fe(CN)(6)(4-) onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Using glucose oxidase (GOD) as the model biorecognition units, we demonstrate the validity of the ferricyanide-based second-generation biosensors for selective in vivo neurochemical measurements. We find that the biosensors developed with the strategy demonstrated in this study can be used well as the selective detector for continuous online detection of striatum glucose of guinea pigs, by integration with in vivo microdialysis. This study essentially paves a new avenue to developing electrochemical biosensors effectively for in vivo neurochemical measurements, which is envisaged to be of great importance in understanding the molecular basis of physiological and pathological events.

  • strong interaction between imidazolium based Polycationic Polymer and ferricyanide toward redox potential regulation for selective in vivo electrochemical measurements
    Analytical Chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)63-) and ferrocyanide (Fe(CN)64-) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)63-/4-, imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)63-/4- due to its stronger interaction with Fe(CN)63- than with Fe(CN)64-. The different adsorption ability of Fe(CN)63- and Fe(CN)64- onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Usin...

Xuming Zhuang - One of the best experts on this subject based on the ideXlab platform.

  • Strong interaction between imidazolium-based Polycationic Polymer and ferricyanide: toward redox potential regulation for selective in vivo electrochemical measurements.
    Analytical chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)(6)(3-)) and ferrocyanide (Fe(CN)(6)(4-)) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)(6)(3-/4-), imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)(6)(3-/4-) due to its stronger interaction with Fe(CN)(6)(3-) than with Fe(CN)(6)(4-). The different adsorption ability of Fe(CN)(6)(3-) and Fe(CN)(6)(4-) onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Using glucose oxidase (GOD) as the model biorecognition units, we demonstrate the validity of the ferricyanide-based second-generation biosensors for selective in vivo neurochemical measurements. We find that the biosensors developed with the strategy demonstrated in this study can be used well as the selective detector for continuous online detection of striatum glucose of guinea pigs, by integration with in vivo microdialysis. This study essentially paves a new avenue to developing electrochemical biosensors effectively for in vivo neurochemical measurements, which is envisaged to be of great importance in understanding the molecular basis of physiological and pathological events.

  • strong interaction between imidazolium based Polycationic Polymer and ferricyanide toward redox potential regulation for selective in vivo electrochemical measurements
    Analytical Chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)63-) and ferrocyanide (Fe(CN)64-) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)63-/4-, imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)63-/4- due to its stronger interaction with Fe(CN)63- than with Fe(CN)64-. The different adsorption ability of Fe(CN)63- and Fe(CN)64- onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Usin...

Haoyuan Chen - One of the best experts on this subject based on the ideXlab platform.

  • Single-Crystal Polycationic Polymers Obtained by Single-Crystal-to-Single-Crystal PhotoPolymerization.
    Journal of the American Chemical Society, 2020
    Co-Authors: Qing-hui Guo, Manping Jia, Zhichang Liu, Yunyan Qiu, Hongliang Chen, Dengke Shen, Xuan Zhang, Matthew R. Ryder, Haoyuan Chen
    Abstract:

    The efficient preparation of single-crystalline ionic Polymers and fundamental understanding of their structure–property relationships at the molecular level remains a challenge in chemistry and materials science. Here, we describe the single-crystal structure of a highly ordered Polycationic Polymer (polyelectrolyte) and its proton conductivity. The polyelectrolyte single crystals can be prepared on a gram-scale in quantitative yield, by taking advantage of an ultraviolet/sunlight-induced topochemical Polymerization, from a tricationic monomer—a self-complementary building block possessing a preorganized conformation. A single-crystal-to-single-crystal photoPolymerization was revealed unambiguously by in situ single-crystal X-ray diffraction analysis, which was also employed to follow the progression of molecular structure from the monomer, to a partially Polymerized intermediate, and, finally, to the Polymer itself. Collinear Polymer chains are held together tightly by multiple Coulombic interactions in...

Wei Jiang - One of the best experts on this subject based on the ideXlab platform.

  • Strong interaction between imidazolium-based Polycationic Polymer and ferricyanide: toward redox potential regulation for selective in vivo electrochemical measurements.
    Analytical chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)(6)(3-)) and ferrocyanide (Fe(CN)(6)(4-)) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)(6)(3-/4-), imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)(6)(3-/4-) due to its stronger interaction with Fe(CN)(6)(3-) than with Fe(CN)(6)(4-). The different adsorption ability of Fe(CN)(6)(3-) and Fe(CN)(6)(4-) onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Using glucose oxidase (GOD) as the model biorecognition units, we demonstrate the validity of the ferricyanide-based second-generation biosensors for selective in vivo neurochemical measurements. We find that the biosensors developed with the strategy demonstrated in this study can be used well as the selective detector for continuous online detection of striatum glucose of guinea pigs, by integration with in vivo microdialysis. This study essentially paves a new avenue to developing electrochemical biosensors effectively for in vivo neurochemical measurements, which is envisaged to be of great importance in understanding the molecular basis of physiological and pathological events.

  • strong interaction between imidazolium based Polycationic Polymer and ferricyanide toward redox potential regulation for selective in vivo electrochemical measurements
    Analytical Chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)63-) and ferrocyanide (Fe(CN)64-) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)63-/4-, imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)63-/4- due to its stronger interaction with Fe(CN)63- than with Fe(CN)64-. The different adsorption ability of Fe(CN)63- and Fe(CN)64- onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Usin...

Lifen Yang - One of the best experts on this subject based on the ideXlab platform.

  • Strong interaction between imidazolium-based Polycationic Polymer and ferricyanide: toward redox potential regulation for selective in vivo electrochemical measurements.
    Analytical chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)(6)(3-)) and ferrocyanide (Fe(CN)(6)(4-)) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)(6)(3-/4-), imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)(6)(3-/4-) due to its stronger interaction with Fe(CN)(6)(3-) than with Fe(CN)(6)(4-). The different adsorption ability of Fe(CN)(6)(3-) and Fe(CN)(6)(4-) onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Using glucose oxidase (GOD) as the model biorecognition units, we demonstrate the validity of the ferricyanide-based second-generation biosensors for selective in vivo neurochemical measurements. We find that the biosensors developed with the strategy demonstrated in this study can be used well as the selective detector for continuous online detection of striatum glucose of guinea pigs, by integration with in vivo microdialysis. This study essentially paves a new avenue to developing electrochemical biosensors effectively for in vivo neurochemical measurements, which is envisaged to be of great importance in understanding the molecular basis of physiological and pathological events.

  • strong interaction between imidazolium based Polycationic Polymer and ferricyanide toward redox potential regulation for selective in vivo electrochemical measurements
    Analytical Chemistry, 2012
    Co-Authors: Xuming Zhuang, Dalei Wang, Yuqing Lin, Lifen Yang, Wei Jiang, Lanqun Mao
    Abstract:

    This study effectively demonstrates a strategy to enable the ferricyanide-based second-generation biosensors for selective in vivo measurements of neurochemicals, with glucose as an example. The strategy is based on regulation of redox potential of ferricyanide mediator by carefully controlling the different adsorption ability of ferricyanide (Fe(CN)63-) and ferrocyanide (Fe(CN)64-) onto electrode surface. To realize the negative shift of the redox potential of Fe(CN)63-/4-, imidazolium-based Polymer (Pim) is synthesized and used as a matrix for surface adsorption of Fe(CN)63-/4- due to its stronger interaction with Fe(CN)63- than with Fe(CN)64-. The different adsorption ability of Fe(CN)63- and Fe(CN)64- onto electrodes modified with a composite of Pim and multiwalled carbon nanotubes (MWNTs) eventually enables the stable surface adsorption of both species to generate integrated biosensors and, more importantly, leads to a negative shift of the redox potential of the surface-confined redox mediator. Usin...