The Experts below are selected from a list of 4509 Experts worldwide ranked by ideXlab platform
Liliana C Tome - One of the best experts on this subject based on the ideXlab platform.
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polymeric ionic liquid based membranes influence of polycation variation on gas transport and co2 selectivity properties
Journal of Membrane Science, 2015Co-Authors: Liliana C Tome, Andreia S L Gouveia, Carmen S R Freire, David Mecerreyes, Isabel M MarruchoAbstract:Abstract This work evaluates the CO2, CH4 and N2 permeation properties of five novel composite membranes based on polymeric ionic liquids (PILs) having different cation pendant units, namely imidazolium, pyridinium, pyrrolidinium, ammonium and cholinium, combined with the same counter-anion ([NTf2]−). The results show that the CO2 permeability in the composite membranes is related to their respective CO2 diffusivities, which are dependent on the PIL polycation nature. The composite membranes of the PILs containing different Polycations and 10 wt% of free ionic liquid (IL) with similar structures to each PIL monomeric unit have CO2 permeabilities between 3.66 and 20.4 Barrer, while they exhibit permselectivities ranging from 28.3 to 43.0 for CO2/CH4 and from 25.8 to 34.7 for CO2/N2. The best CO2 permselectivities were obtained when tetra-alkyl ammonium-based PILs (pyrrolidinium, ammonium and cholinium) are used rather than imidazolium or pyridinium. Also, the results of this work indicate that the polycation backbones of PILs can also play a significant role in the design of PIL–IL membranes with the finest gas permeation properties and improved CO2 separation performances.
Moreno-villoslada Ignacio - One of the best experts on this subject based on the ideXlab platform.
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Controlling the aggregation of 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin by the use of Polycations derived from polyketones bearing charged aromatic groups
2013Co-Authors: Toncelli Claudio, Pino-pinto, Juan Pablo, Sano Naoki, Picchioni Francesco, Broekhuis, Antonius A., Nishide Hiroyuki, Moreno-villoslada IgnacioAbstract:The interaction between 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin and different Polycations is studied by UV–vis spectroscopy. Two Polycations containing charged aromatic residues (imidazolium and pyridinium) have been easily synthesized by Paal–Knorr reaction of alternating aliphatic polyketones with histamine and 4-picolylamine. It was found that these polymers stabilize the tetra-anionic form of the porphyrin at acidic conditions, and avoid the formation of H- and J-type self-aggregates. Other Polycations such as poly(allylamine) and poly(decylviologen) enhance porphyrin self-aggregation. As the latter polymer has also aromatic charged groups, the influence of the polymer structure as a whole in the behavior of the porphyrin/polycation system is highlighted. In this context, similar but not equal results have been found comparing the influence of the polyketone derivative containing pyridinium groups and the polycation poly(4-vinylpyridine) on the porphyrin self-aggregation and acid–base behavior.
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Controlling the aggregation of 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin by the use of Polycations derived from polyketones bearing charged aromatic groups
'Elsevier BV', 2013Co-Authors: Toncelli Claudio, Sano Naoki, Picchioni Francesco, Broekhuis, Antonius A., Nishide Hiroyuki, Pablo Pino-pinto Juan, Moreno-villoslada IgnacioAbstract:The interaction between 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin and different Polycations is studied by UV-vis spectroscopy. Two Polycations containing charged aromatic residues (imidazolium and pyridinium) have been easily synthesized by Paal-Knorr reaction of alternating aliphatic polyketones with histamine and 4-picolylamine. It was found that these polymers stabilize the tetra-anionic form of the porphyrin at acidic conditions, and avoid the formation of H- and J-type self-aggregates. Other Polycations such as poly(allylamine) and poly(decylviologen) enhance porphyrin self-aggregation. As the latter polymer has also aromatic charged groups, the influence of the polymer structure as a whole in the behavior of the porphyrin/polycation system is highlighted. In this context, similar but not equal results have been found comparing the influence of the polyketone derivative containing pyridinium groups and the polycation poly(4-vinylpyridine) on the porphyrin self-aggregation and acid base behavior. (C) 2013 Elsevier Ltd. All rights reserved
Guangzhao Mao - One of the best experts on this subject based on the ideXlab platform.
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layer by layer dna films incorporating highly transfecting bioreducible poly amido amine and polyethylenimine for sequential gene delivery
International Journal of Nanomedicine, 2018Co-Authors: Lingxiao Xie, Xiong Ding, Rachel Budry, Guangzhao MaoAbstract:Background The layer-by-layer (LbL) assembly method offers a molecular level control of the amount and spatial distribution of bioactive molecules. However, successful clinical translation of LbL film technology will most certainly require a better understanding and control of not only the film assembly process, but also film disassembly kinetics in physiologic conditions. Purpose This work focuses on the understanding and control of degradation properties of LbL films for localized gene delivery. Methods Bioreducible poly(amido amine)s (PAAs) containing cystaminebisacrylamide (CBA), methylenebisacrylamide, and 5-amino-1-pentanol (APOL) were synthesized by Michael addition polymerization for the construction of bioreducible LbL films capable of sequential gene delivery. Results The synthesized PAAs were screened for desirable buffering capacity, cell transfection, and cytotoxicity characteristics together with 25 kDa branched polyethylenimine (PEI) and cross-linked 800 Da PEI. By screening the various Polycations we were able to identify a copolymer of CBA and APOL for the subsequent construction of the LbL films. By incorporating a highly transfecting polycation and a nondiffusing polycation we were able to improve the overall transfection of HEK293 and MC3T3 cells from the bioreducible LbL films. We also demonstrated the dual-stage release and transfection of two different DNAs from the LbL films. Conclusion The results indicate that LbL films consisting of bioreducible PAAs and non-diffusing polyelectrolytes have excellent degradation properties for the development of LbL coating technology for localized gene delivery applications.
Isabel M Marrucho - One of the best experts on this subject based on the ideXlab platform.
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polymeric ionic liquid based membranes influence of polycation variation on gas transport and co2 selectivity properties
Journal of Membrane Science, 2015Co-Authors: Liliana C Tome, Andreia S L Gouveia, Carmen S R Freire, David Mecerreyes, Isabel M MarruchoAbstract:Abstract This work evaluates the CO2, CH4 and N2 permeation properties of five novel composite membranes based on polymeric ionic liquids (PILs) having different cation pendant units, namely imidazolium, pyridinium, pyrrolidinium, ammonium and cholinium, combined with the same counter-anion ([NTf2]−). The results show that the CO2 permeability in the composite membranes is related to their respective CO2 diffusivities, which are dependent on the PIL polycation nature. The composite membranes of the PILs containing different Polycations and 10 wt% of free ionic liquid (IL) with similar structures to each PIL monomeric unit have CO2 permeabilities between 3.66 and 20.4 Barrer, while they exhibit permselectivities ranging from 28.3 to 43.0 for CO2/CH4 and from 25.8 to 34.7 for CO2/N2. The best CO2 permselectivities were obtained when tetra-alkyl ammonium-based PILs (pyrrolidinium, ammonium and cholinium) are used rather than imidazolium or pyridinium. Also, the results of this work indicate that the polycation backbones of PILs can also play a significant role in the design of PIL–IL membranes with the finest gas permeation properties and improved CO2 separation performances.
David Mecerreyes - One of the best experts on this subject based on the ideXlab platform.
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polymeric ionic liquid based membranes influence of polycation variation on gas transport and co2 selectivity properties
Journal of Membrane Science, 2015Co-Authors: Liliana C Tome, Andreia S L Gouveia, Carmen S R Freire, David Mecerreyes, Isabel M MarruchoAbstract:Abstract This work evaluates the CO2, CH4 and N2 permeation properties of five novel composite membranes based on polymeric ionic liquids (PILs) having different cation pendant units, namely imidazolium, pyridinium, pyrrolidinium, ammonium and cholinium, combined with the same counter-anion ([NTf2]−). The results show that the CO2 permeability in the composite membranes is related to their respective CO2 diffusivities, which are dependent on the PIL polycation nature. The composite membranes of the PILs containing different Polycations and 10 wt% of free ionic liquid (IL) with similar structures to each PIL monomeric unit have CO2 permeabilities between 3.66 and 20.4 Barrer, while they exhibit permselectivities ranging from 28.3 to 43.0 for CO2/CH4 and from 25.8 to 34.7 for CO2/N2. The best CO2 permselectivities were obtained when tetra-alkyl ammonium-based PILs (pyrrolidinium, ammonium and cholinium) are used rather than imidazolium or pyridinium. Also, the results of this work indicate that the polycation backbones of PILs can also play a significant role in the design of PIL–IL membranes with the finest gas permeation properties and improved CO2 separation performances.
