The Experts below are selected from a list of 15705 Experts worldwide ranked by ideXlab platform

Nabil Chakfé - One of the best experts on this subject based on the ideXlab platform.

  • fiber heart valve prosthesis early in vitro fatigue results
    Journal of Biomedical Materials Research Part B, 2016
    Co-Authors: Antoine Vaesken, Foued Khoffi, Frederic Heim, Florence Dieval, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement has become today a largely considered alternative technique to surgical valve replacement in patients with high risk for open chest surgery. Biological valve tissue used in the transcatheter devices has shown success over 5 years now, but the procedure remains expensive. Moreover, different studies point out potential degradations that the tissue can undergo when folded to lower diameter and released in calcified environment with irregular geometry, which may jeopardize the durability of the device. The use of synthetic Materials, like textile in particular, to replace biological valve leaflets would help reducing the procedure costs, and limit the degradations when the valve is crimped. Textile Polyester Material has been extensively used in the vascular surgery and is characterized by outstanding folding and strength properties combined with proven biocompatibility. However, the friction effects that occur between filaments and between yarns within a fabric under flexure loading could be critical for the resistance of the Material on the long term. The purpose of this study was to assess the early fatigue performances of textile valve prototypes under accelerated cyclic loading up to 200 Mio cycles. Durability tests show that the fibrous Material undergoes rearrangements between fibrous elements within the textile construction and the mechanical properties are modified on the long term. But testing is not complete with 200 Mio cycles. The Material should be tested up to a higher number of cycles in future work to test the effective long-term durability. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 986-992, 2016.

  • transcatheter fiber heart valve effect of crimping on Material performances
    Journal of Biomedical Materials Research Part B, 2015
    Co-Authors: Foued Khoffi, Nabil Chakfé, Frederic Heim, Jason T. Lee
    Abstract:

    Transcatheter aortic valve implantation (TAVI) has become a popular alternative technique to surgical valve replacement. However, the biological valve tissue used in these devices appears to be fragile Material in the long term particularly due being folded for low diameter catheter insertion purposes and when released in a calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could therefore be considered as a replacement for biological valve leaflets in the TAVI procedure. The folding process associated with crimping, however, may degrade the filaments involved in the fibrous assembly and limit the durability of the device. The purpose of the present work is to study the effect of different crimping conditions on the mechanical performances of textile valve prototypes made from various fabric constructions. Results show that crimping generates some creases in the fabrics, which surface topography varies with fabric construction and crimping configuration. The mechanical properties of the crimped Materials are globally slightly reduced. To determine how critical the modifications due to crimping are for prosthesis durability, more detailed long term in vitro and in vivo trials with crimped textile prototypes are needed in addition to this preliminary work. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 103B: 1488–1497, 2015.

  • fiber heart valve prosthesis influence of the fabric construction parameters on the valve fatigue performances
    Journal of The Mechanical Behavior of Biomedical Materials, 2014
    Co-Authors: Antoine Vaesken, Frederic Heim, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement (TAVR) has become today a largely considered alternative technique to surgical valve replacement in patients who are not operable or patients with high risk for open chest surgery. However, the biological valve tissue used in the devices implanted clinically appears to be fragile Material when folded for low diameter catheter insertion purpose and released in calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could thereof be considered to replace biological valve leaflets in the TAVR procedure. The textile construction parameters must however be tuned to obtain a Material compatible with the valve requested durability. In that context, one issue to be addressed is the friction effect that occurs between filaments and between yarns within a fabric under flexure loading. This phenomenon could be critical for the resistance of the Material on the long term. The purpose of the present work is to assess the fatigue performances of textile valve prototypes made from different fabric constructions (monofilament, multifilament, calendered mutifilament) under accelerated cyclic loading. The goal is to identify, which construction is the best suited to long term fatigue stress. Results show that calendered multifilament and monofilament fabric constructions undergo strong ruptures already from 40 Mio cycles, while non calendered multifilament appears more durable. The rupture patterns observed point out that durability is directly related to the flexure stiffness level of the fibrous elements in the construction.

Frederic Heim - One of the best experts on this subject based on the ideXlab platform.

  • fiber heart valve prosthesis early in vitro fatigue results
    Journal of Biomedical Materials Research Part B, 2016
    Co-Authors: Antoine Vaesken, Foued Khoffi, Frederic Heim, Florence Dieval, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement has become today a largely considered alternative technique to surgical valve replacement in patients with high risk for open chest surgery. Biological valve tissue used in the transcatheter devices has shown success over 5 years now, but the procedure remains expensive. Moreover, different studies point out potential degradations that the tissue can undergo when folded to lower diameter and released in calcified environment with irregular geometry, which may jeopardize the durability of the device. The use of synthetic Materials, like textile in particular, to replace biological valve leaflets would help reducing the procedure costs, and limit the degradations when the valve is crimped. Textile Polyester Material has been extensively used in the vascular surgery and is characterized by outstanding folding and strength properties combined with proven biocompatibility. However, the friction effects that occur between filaments and between yarns within a fabric under flexure loading could be critical for the resistance of the Material on the long term. The purpose of this study was to assess the early fatigue performances of textile valve prototypes under accelerated cyclic loading up to 200 Mio cycles. Durability tests show that the fibrous Material undergoes rearrangements between fibrous elements within the textile construction and the mechanical properties are modified on the long term. But testing is not complete with 200 Mio cycles. The Material should be tested up to a higher number of cycles in future work to test the effective long-term durability. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 986-992, 2016.

  • transcatheter fiber heart valve effect of crimping on Material performances
    Journal of Biomedical Materials Research Part B, 2015
    Co-Authors: Foued Khoffi, Nabil Chakfé, Frederic Heim, Jason T. Lee
    Abstract:

    Transcatheter aortic valve implantation (TAVI) has become a popular alternative technique to surgical valve replacement. However, the biological valve tissue used in these devices appears to be fragile Material in the long term particularly due being folded for low diameter catheter insertion purposes and when released in a calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could therefore be considered as a replacement for biological valve leaflets in the TAVI procedure. The folding process associated with crimping, however, may degrade the filaments involved in the fibrous assembly and limit the durability of the device. The purpose of the present work is to study the effect of different crimping conditions on the mechanical performances of textile valve prototypes made from various fabric constructions. Results show that crimping generates some creases in the fabrics, which surface topography varies with fabric construction and crimping configuration. The mechanical properties of the crimped Materials are globally slightly reduced. To determine how critical the modifications due to crimping are for prosthesis durability, more detailed long term in vitro and in vivo trials with crimped textile prototypes are needed in addition to this preliminary work. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 103B: 1488–1497, 2015.

  • fiber heart valve prosthesis influence of the fabric construction parameters on the valve fatigue performances
    Journal of The Mechanical Behavior of Biomedical Materials, 2014
    Co-Authors: Antoine Vaesken, Frederic Heim, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement (TAVR) has become today a largely considered alternative technique to surgical valve replacement in patients who are not operable or patients with high risk for open chest surgery. However, the biological valve tissue used in the devices implanted clinically appears to be fragile Material when folded for low diameter catheter insertion purpose and released in calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could thereof be considered to replace biological valve leaflets in the TAVR procedure. The textile construction parameters must however be tuned to obtain a Material compatible with the valve requested durability. In that context, one issue to be addressed is the friction effect that occurs between filaments and between yarns within a fabric under flexure loading. This phenomenon could be critical for the resistance of the Material on the long term. The purpose of the present work is to assess the fatigue performances of textile valve prototypes made from different fabric constructions (monofilament, multifilament, calendered mutifilament) under accelerated cyclic loading. The goal is to identify, which construction is the best suited to long term fatigue stress. Results show that calendered multifilament and monofilament fabric constructions undergo strong ruptures already from 40 Mio cycles, while non calendered multifilament appears more durable. The rupture patterns observed point out that durability is directly related to the flexure stiffness level of the fibrous elements in the construction.

Antoine Vaesken - One of the best experts on this subject based on the ideXlab platform.

  • fiber heart valve prosthesis early in vitro fatigue results
    Journal of Biomedical Materials Research Part B, 2016
    Co-Authors: Antoine Vaesken, Foued Khoffi, Frederic Heim, Florence Dieval, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement has become today a largely considered alternative technique to surgical valve replacement in patients with high risk for open chest surgery. Biological valve tissue used in the transcatheter devices has shown success over 5 years now, but the procedure remains expensive. Moreover, different studies point out potential degradations that the tissue can undergo when folded to lower diameter and released in calcified environment with irregular geometry, which may jeopardize the durability of the device. The use of synthetic Materials, like textile in particular, to replace biological valve leaflets would help reducing the procedure costs, and limit the degradations when the valve is crimped. Textile Polyester Material has been extensively used in the vascular surgery and is characterized by outstanding folding and strength properties combined with proven biocompatibility. However, the friction effects that occur between filaments and between yarns within a fabric under flexure loading could be critical for the resistance of the Material on the long term. The purpose of this study was to assess the early fatigue performances of textile valve prototypes under accelerated cyclic loading up to 200 Mio cycles. Durability tests show that the fibrous Material undergoes rearrangements between fibrous elements within the textile construction and the mechanical properties are modified on the long term. But testing is not complete with 200 Mio cycles. The Material should be tested up to a higher number of cycles in future work to test the effective long-term durability. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 986-992, 2016.

  • fiber heart valve prosthesis influence of the fabric construction parameters on the valve fatigue performances
    Journal of The Mechanical Behavior of Biomedical Materials, 2014
    Co-Authors: Antoine Vaesken, Frederic Heim, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement (TAVR) has become today a largely considered alternative technique to surgical valve replacement in patients who are not operable or patients with high risk for open chest surgery. However, the biological valve tissue used in the devices implanted clinically appears to be fragile Material when folded for low diameter catheter insertion purpose and released in calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could thereof be considered to replace biological valve leaflets in the TAVR procedure. The textile construction parameters must however be tuned to obtain a Material compatible with the valve requested durability. In that context, one issue to be addressed is the friction effect that occurs between filaments and between yarns within a fabric under flexure loading. This phenomenon could be critical for the resistance of the Material on the long term. The purpose of the present work is to assess the fatigue performances of textile valve prototypes made from different fabric constructions (monofilament, multifilament, calendered mutifilament) under accelerated cyclic loading. The goal is to identify, which construction is the best suited to long term fatigue stress. Results show that calendered multifilament and monofilament fabric constructions undergo strong ruptures already from 40 Mio cycles, while non calendered multifilament appears more durable. The rupture patterns observed point out that durability is directly related to the flexure stiffness level of the fibrous elements in the construction.

Foued Khoffi - One of the best experts on this subject based on the ideXlab platform.

  • fiber heart valve prosthesis early in vitro fatigue results
    Journal of Biomedical Materials Research Part B, 2016
    Co-Authors: Antoine Vaesken, Foued Khoffi, Frederic Heim, Florence Dieval, Nabil Chakfé
    Abstract:

    Transcatheter aortic valve replacement has become today a largely considered alternative technique to surgical valve replacement in patients with high risk for open chest surgery. Biological valve tissue used in the transcatheter devices has shown success over 5 years now, but the procedure remains expensive. Moreover, different studies point out potential degradations that the tissue can undergo when folded to lower diameter and released in calcified environment with irregular geometry, which may jeopardize the durability of the device. The use of synthetic Materials, like textile in particular, to replace biological valve leaflets would help reducing the procedure costs, and limit the degradations when the valve is crimped. Textile Polyester Material has been extensively used in the vascular surgery and is characterized by outstanding folding and strength properties combined with proven biocompatibility. However, the friction effects that occur between filaments and between yarns within a fabric under flexure loading could be critical for the resistance of the Material on the long term. The purpose of this study was to assess the early fatigue performances of textile valve prototypes under accelerated cyclic loading up to 200 Mio cycles. Durability tests show that the fibrous Material undergoes rearrangements between fibrous elements within the textile construction and the mechanical properties are modified on the long term. But testing is not complete with 200 Mio cycles. The Material should be tested up to a higher number of cycles in future work to test the effective long-term durability. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 986-992, 2016.

  • transcatheter fiber heart valve effect of crimping on Material performances
    Journal of Biomedical Materials Research Part B, 2015
    Co-Authors: Foued Khoffi, Nabil Chakfé, Frederic Heim, Jason T. Lee
    Abstract:

    Transcatheter aortic valve implantation (TAVI) has become a popular alternative technique to surgical valve replacement. However, the biological valve tissue used in these devices appears to be fragile Material in the long term particularly due being folded for low diameter catheter insertion purposes and when released in a calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could therefore be considered as a replacement for biological valve leaflets in the TAVI procedure. The folding process associated with crimping, however, may degrade the filaments involved in the fibrous assembly and limit the durability of the device. The purpose of the present work is to study the effect of different crimping conditions on the mechanical performances of textile valve prototypes made from various fabric constructions. Results show that crimping generates some creases in the fabrics, which surface topography varies with fabric construction and crimping configuration. The mechanical properties of the crimped Materials are globally slightly reduced. To determine how critical the modifications due to crimping are for prosthesis durability, more detailed long term in vitro and in vivo trials with crimped textile prototypes are needed in addition to this preliminary work. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 103B: 1488–1497, 2015.

Jason T. Lee - One of the best experts on this subject based on the ideXlab platform.

  • transcatheter fiber heart valve effect of crimping on Material performances
    Journal of Biomedical Materials Research Part B, 2015
    Co-Authors: Foued Khoffi, Nabil Chakfé, Frederic Heim, Jason T. Lee
    Abstract:

    Transcatheter aortic valve implantation (TAVI) has become a popular alternative technique to surgical valve replacement. However, the biological valve tissue used in these devices appears to be fragile Material in the long term particularly due being folded for low diameter catheter insertion purposes and when released in a calcified environment with irregular geometry. Textile Polyester Material is characterized by outstanding folding and strength properties combined with proven biocompatibility. It could therefore be considered as a replacement for biological valve leaflets in the TAVI procedure. The folding process associated with crimping, however, may degrade the filaments involved in the fibrous assembly and limit the durability of the device. The purpose of the present work is to study the effect of different crimping conditions on the mechanical performances of textile valve prototypes made from various fabric constructions. Results show that crimping generates some creases in the fabrics, which surface topography varies with fabric construction and crimping configuration. The mechanical properties of the crimped Materials are globally slightly reduced. To determine how critical the modifications due to crimping are for prosthesis durability, more detailed long term in vitro and in vivo trials with crimped textile prototypes are needed in addition to this preliminary work. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 103B: 1488–1497, 2015.