The Experts below are selected from a list of 7710 Experts worldwide ranked by ideXlab platform
Jeffrey W. Bode - One of the best experts on this subject based on the ideXlab platform.
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Kinetic resolution of nitrogen heterocycles with a reusable Polymer-Supported Reagent.
Angewandte Chemie International Edition, 2012Co-Authors: Imants Kreituss, Yuta Murakami, Michael Binanzer, Jeffrey W. BodeAbstract:Shake it up baby! Simply shaking a Polymer-Supported Reagent and the racemic amine at room temperature kinetically resolves a broad range of N-heterocycles with good selectivity. The Polymer-Supported Reagents are robust, easy to regenerate, and can be reused dozens of times. Cleavable acyl groups can be used to give access to both amine enantiomers in a single resolution.
Charles Mioskowski - One of the best experts on this subject based on the ideXlab platform.
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Unprecedented, fully recyclable, solid-supported Reagent for the kinetic resolution of racemic amines through enantioselective N-acetylation
Chemical Communications, 2005Co-Authors: Stellios Arseniyadis, Pithani V. Subhash, Alain Valleix, Alain Wagner, Charles MioskowskiAbstract:The high-yielding synthesis and application of the first polymer supported Reagent for the kinetic resolution (KR) of amines through enantioselective acetylation is described; this new supported chiral Reagent allows the KR of primary amines with excellent selectivities at room temperature; moreover, this supported approach is highly efficient as the Merrifield-supported chiral scaffold can be quantitatively recovered and recycled.
Imants Kreituss - One of the best experts on this subject based on the ideXlab platform.
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Kinetic resolution of nitrogen heterocycles with a reusable Polymer-Supported Reagent.
Angewandte Chemie International Edition, 2012Co-Authors: Imants Kreituss, Yuta Murakami, Michael Binanzer, Jeffrey W. BodeAbstract:Shake it up baby! Simply shaking a Polymer-Supported Reagent and the racemic amine at room temperature kinetically resolves a broad range of N-heterocycles with good selectivity. The Polymer-Supported Reagents are robust, easy to regenerate, and can be reused dozens of times. Cleavable acyl groups can be used to give access to both amine enantiomers in a single resolution.
Stellios Arseniyadis - One of the best experts on this subject based on the ideXlab platform.
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Unprecedented, fully recyclable, solid-supported Reagent for the kinetic resolution of racemic amines through enantioselective N-acetylation
Chemical Communications, 2005Co-Authors: Stellios Arseniyadis, Pithani V. Subhash, Alain Valleix, Alain Wagner, Charles MioskowskiAbstract:The high-yielding synthesis and application of the first polymer supported Reagent for the kinetic resolution (KR) of amines through enantioselective acetylation is described; this new supported chiral Reagent allows the KR of primary amines with excellent selectivities at room temperature; moreover, this supported approach is highly efficient as the Merrifield-supported chiral scaffold can be quantitatively recovered and recycled.
Maurizio Taddei - One of the best experts on this subject based on the ideXlab platform.
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A New Polymer-Supported Reagent for the Synthesis of β-Lactams in Solution
The Journal of organic chemistry, 2004Co-Authors: Donato Donati, Costanza Morelli, Andrea Porcheddu, Maurizio TaddeiAbstract:A modified Mukaiyama Reagent was prepared on a PS-DVB resin. This Reagent was used for the preparation of β-lactams, using the Staudinger reaction. The products were obtained by generating the ketene from a carboxylic acid under sonication with the resin followed by reaction with the imine. Excess of the imine was removed by reduction followed by acid scavenging.