The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform
Meirong Wang - One of the best experts on this subject based on the ideXlab platform.
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diffusion tensor imaging study of brain precentral Gyrus and Postcentral Gyrus during normal brain aging process
Brain and behavior, 2020Co-Authors: Ling Zhou, Na Tian, Zuojun Geng, Liying Dong, Meirong WangAbstract:OBJECTIVE To study the changes of white matter tracts in precentral Gyrus and Postcentral Gyrus during normal brain aging process by analyzing fractional anisotropy (FA) values obtained from diffusion tensor imaging (DTI) technology. METHODS Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were conducted on 120 healthy right-handed subjects. The subjects were separated into four age groups, namely Young Male/Female ( 45 years old). Each subject undertakes routine MRI and DTI scans. Left/right precentral and left/right Postcentral Gyrus are automatically detected on the image. The area for region of interest (ROI) is set to be 18 ± 2 mm2 . RESULTS For each age group, the FA values of white matter in precentral Gyrus and Postcentral Gyrus are statistically different (p < .05) in both left and right sides of the brain across different age groups and genders. Additionally, the FA values are statistically different (p < .05) between two young and senior age groups across different genders, brain regions, and hemispheres. CONCLUSION The FA values of precentral Gyrus and Postcentral Gyrus are statistically different across genders, age groups, and hemispheres. Additionally, the FA values of both precentral Gyrus and Postcentral Gyrus decrease over time, which is a strong indication of aging.
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Diffusion tensor imaging study of brain precentral Gyrus and Postcentral Gyrus during normal brain aging process.
Brain and behavior, 2020Co-Authors: Ling Zhou, Na Tian, Zuojun Geng, Liying Dong, Meirong WangAbstract:OBJECTIVE To study the changes of white matter tracts in precentral Gyrus and Postcentral Gyrus during normal brain aging process by analyzing fractional anisotropy (FA) values obtained from diffusion tensor imaging (DTI) technology. METHODS Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were conducted on 120 healthy right-handed subjects. The subjects were separated into four age groups, namely Young Male/Female ( 45 years old). Each subject undertakes routine MRI and DTI scans. Left/right precentral and left/right Postcentral Gyrus are automatically detected on the image. The area for region of interest (ROI) is set to be 18 ± 2 mm2 . RESULTS For each age group, the FA values of white matter in precentral Gyrus and Postcentral Gyrus are statistically different (p
Burkhard Pleger - One of the best experts on this subject based on the ideXlab platform.
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The perception of touch and the ventral somatosensory pathway
Brain, 2014Co-Authors: Sven Preusser, Sabrina D. Thiel, Carolin Rook, Elisabeth Roggenhofer, Anna Kosatschek, Bogdan Draganski, Felix Blankenburg, Jon Driver, Arno Villringer, Burkhard PlegerAbstract:In humans, touching the skin is known to activate, among others, the contralateral primary somatosensory cortex on the Postcentral Gyrus together with the bilateral parietal operculum (i.e. the anatomical site of the secondary somatosensory cortex). But which brain regions beyond the Postcentral Gyrus specifically contribute to the perception of touch remains speculative. In this study we collected structural magnetic resonance imaging scans and neurological examination reports of patients with brain injuries or stroke in the left or right hemisphere, but not in the Postcentral Gyrus as the entry site of cortical somatosensory processing. Using voxel-based lesion-symptom mapping, we compared patients with impaired touch perception (i.e. hypoaesthesia) to patients without such touch impairments. Patients with hypoaesthesia as compared to control patients differed in one single brain cluster comprising the contralateral parietal operculum together with the anterior and posterior insular cortex, the putamen, as well as subcortical white matter connections reaching ventrally towards prefrontal structures. This finding confirms previous speculations on the ‘ventral pathway of somatosensory perception’ and causally links these brain structures to the perception of touch.
Jong S. Kim - One of the best experts on this subject based on the ideXlab platform.
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Patterns of sensory abnormality in cortical stroke: evidence for a dichotomized sensory system.
Neurology, 2007Co-Authors: Jong S. KimAbstract:Objective: To characterize sensory symptoms in patients with stroke occurring in the cerebral cortex. Methods: We studied clinical and imaging findings of 24 patients who had prominent sensory symptoms without definitive motor dysfunction. Results: According to the sensory manifestations, patients were divided into dominant impairment of primitive sensation (DIPS) group, dominant impairment of cortical sensation (DICS) group, and paresthesia-only group. DIPS was related to lesions involving the parietal operculum and the insular cortex, whereas DICS was related to the lesions affecting the Postcentral Gyrus. Patients with paresthesia only had smaller lesions located in the Postcentral Gyrus. DIPS group patients were more often women ( p = 0.013), more often had dysarthria (n = 0.043), and more often developed central poststroke pain or paresthesia (n = 0.005) than the DICS group patients. Restricted sensory changes are common, predominantly involving the perioral or finger areas. Conclusions: Sensory patterns in these patients are generally consistent with the dichotomized (SI and SII) sensory system in the cerebral cortex. Involvement of insular and opercular areas is related to primitive sensory impairment and development of central poststroke pain, whereas Postcentral Gyrus involvement is related to cortical sensory loss without poststroke pain. The pattern of restricted sensory changes is generally consistent with the Penfield sensory topography.
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Patterns of sensory abnormality in cortical stroke : Evidence for a dichotomized sensory system. Commentary
Neurology, 2007Co-Authors: Krish Sathian, Jong S. KimAbstract:Objective: To characterize sensory symptoms in patients with stroke occurring in the cerebral cortex. Methods: We studied clinical and imaging findings of 24 patients who had prominent sensory symptoms without definitive motor dysfunction. Results: According to the sensory manifestations, patients were divided into dominant impairment of primitive sensation (DIPS) group, dominant impairment of cortical sensation (DICS) group, and paresthesia-only group. DIPS was related to lesions involving the parietal operculum and the insular cortex, whereas DICS was related to the lesions affecting the Postcentral Gyrus. Patients with paresthesia only had smaller lesions located in the Postcentral Gyrus. DIPS group patients were more often women (p = 0.013), more often had dysarthria (n = 0.043), and more often developed central poststroke pain or paresthesia (n = 0.005) than the DICS group patients. Restricted sensory changes are common, predominantly involving the perioral or finger areas. Conclusions: Sensory patterns in these patients are generally consistent with the dichotomized (SI and SII) sensory system in the cerebral cortex. Involvement of insular and opercular areas is related to primitive sensory impairment and development of central poststroke pain, whereas Postcentral Gyrus involvement is related to cortical sensory loss without poststroke pain. The pattern of restricted sensory changes is generally consistent with the Penfield sensory topography.
Ling Zhou - One of the best experts on this subject based on the ideXlab platform.
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diffusion tensor imaging study of brain precentral Gyrus and Postcentral Gyrus during normal brain aging process
Brain and behavior, 2020Co-Authors: Ling Zhou, Na Tian, Zuojun Geng, Liying Dong, Meirong WangAbstract:OBJECTIVE To study the changes of white matter tracts in precentral Gyrus and Postcentral Gyrus during normal brain aging process by analyzing fractional anisotropy (FA) values obtained from diffusion tensor imaging (DTI) technology. METHODS Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were conducted on 120 healthy right-handed subjects. The subjects were separated into four age groups, namely Young Male/Female ( 45 years old). Each subject undertakes routine MRI and DTI scans. Left/right precentral and left/right Postcentral Gyrus are automatically detected on the image. The area for region of interest (ROI) is set to be 18 ± 2 mm2 . RESULTS For each age group, the FA values of white matter in precentral Gyrus and Postcentral Gyrus are statistically different (p < .05) in both left and right sides of the brain across different age groups and genders. Additionally, the FA values are statistically different (p < .05) between two young and senior age groups across different genders, brain regions, and hemispheres. CONCLUSION The FA values of precentral Gyrus and Postcentral Gyrus are statistically different across genders, age groups, and hemispheres. Additionally, the FA values of both precentral Gyrus and Postcentral Gyrus decrease over time, which is a strong indication of aging.
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Diffusion tensor imaging study of brain precentral Gyrus and Postcentral Gyrus during normal brain aging process.
Brain and behavior, 2020Co-Authors: Ling Zhou, Na Tian, Zuojun Geng, Liying Dong, Meirong WangAbstract:OBJECTIVE To study the changes of white matter tracts in precentral Gyrus and Postcentral Gyrus during normal brain aging process by analyzing fractional anisotropy (FA) values obtained from diffusion tensor imaging (DTI) technology. METHODS Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were conducted on 120 healthy right-handed subjects. The subjects were separated into four age groups, namely Young Male/Female ( 45 years old). Each subject undertakes routine MRI and DTI scans. Left/right precentral and left/right Postcentral Gyrus are automatically detected on the image. The area for region of interest (ROI) is set to be 18 ± 2 mm2 . RESULTS For each age group, the FA values of white matter in precentral Gyrus and Postcentral Gyrus are statistically different (p
Ben-yan Luo - One of the best experts on this subject based on the ideXlab platform.
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271 – Gray matter reduction associated with cognitive dysfunction in first-episode, treatment-naive young adults with major depressive disorder: a voxel-based morphometry study
European Psychiatry, 2013Co-Authors: Manli Huang, Ben-yan LuoAbstract:Introduction The association between gray matter and cognitive dysfunction in young major depression remains unclear. Objectives To investigate the brain gray matter and the correlation with cognitive function in first-episode, treatment-naive patients with major depressive disorder (MDD). Aims To explore brain structural pathological mechanisms of cognitive impairment in MDD. Methods 46 MDD aged 18-45 year and 46 controls were assessed by Wisconsin Card Sorting Test (WCST) and Trail making test (TMT). Then, 30 patients and 30 controls were obtained by MRI scan. Results The total number of errors, number of preservative errors, random errors of WSCT in MDD were significantly more than that in controls, and the completion time in the TMT-A and TMT-B was longer than that in controls. MDD showed significant less gray matter volumns than controls in frontal lobe (right precentral Gyrus, bilateral superior frontal Gyrus and right middle frontal Gyrus), parietal lobe (left Postcentral Gyrus, left paracentral lobule, and bilateral precuneus), temporal lobe (right superior temporal Gyrus), and occipital lobe (left superior occipital Gyrus). There was a significant negative correlation between left Postcentral Gyrus and left superior occipital Gyrus gray matter density and the TMT-B completion time (r=-0.462, P=0.017; r=-0.448, P=0.022). Conclusions The first-episode MDD patient exhibiteded cognitive impairment and showed significant lower gray matter density than controls in frontal lobe, parietal lobe, temporal lobe, occipital lobe. Decreased gray matter density in left Postcentral Gyrus and left superior occipital Gyrus may be involved in the executive dysfunction.