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Mary Ann Croft - One of the best experts on this subject based on the ideXlab platform.
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Surgical intervention and accommodative responses, II: Forward ciliary body accommodative movement is facilitated by zonular attachments to the Lens Capsule. Invest Ophthalmol Vis Sci
2015Co-Authors: Rainer Wasilewski, Jared P Mcdonald, Paul L Kaufman, Gregg Heatley, Mary Ann CroftAbstract:PURPOSE. To determine the role of the Lens and the Lens Capsule in the three-dimensional architecture of the ciliary muscle at rest and during accommodation, in live rhesus monkeys and in histologic sections, by removing the entire Lens, or only the Lens nucleus and cortex, while leaving the Posterior Capsule in place. METHODS. In 15 rhesus monkey eyes, aged 6 to 27 years, accommodation was induced by central stimulation of the Edinger-Westphal nucleus before and after intra- or extracap-sular Lens extraction (ICLE, ECLE). Forward ciliary body move-ment and ciliary body width were measured by ultrasound biomicroscopy (UBM, 50 MHz). The monkeys were then killed, the eyes were examined morphologically in 1-m sections, and the shape of the ciliary muscle was compared with that ob-tained from UBM images. RESULTS. The shape of the ciliary muscle in eyes undergoing ECLE (n 5) did not differ from that in control eyes. In contrast, after ICLE (n 10), accommodative forward ciliary body movement (P 0.01) and thickness were decreased (P 0.001), length was increased (P 0.058), and the inner apex was located more Posteriorly than in control eyes (P 0.005). Histologic and in vivo data were similar and showed that the ciliary muscle maintained its triangular shape only if the Lens Capsule (with or without the Lens substance) was present. CONCLUSIONS. The Posterior Lens Capsule and anterior zonular attachments facilitate forward accommodative ciliary body movement. Lens substance extraction procedures that leave the Posterior Capsule intact, similar to those used clinically, do not affect the Capsule/zonular/muscular system move-ments, an important finding for accommodating intraocula
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surgical intervention and accommodative responses ii forward ciliary body accommodative movement is facilitated by zonular attachments to the Lens Capsule
Investigative Ophthalmology & Visual Science, 2008Co-Authors: Rainer Wasilewski, Jared P Mcdonald, Gregg A Heatley, Elke Lutjendrecoll, Paul L Kaufman, Mary Ann CroftAbstract:PURPOSE: To determine the role of the Lens and the Lens Capsule in the three-dimensional architecture of the ciliary muscle at rest and during accommodation, in live rhesus monkeys and in histologic sections, by removing the entire Lens, or only the Lens nucleus and cortex, while leaving the Posterior Capsule in place. METHODS: In 15 rhesus monkey eyes, aged 6 to 27 years, accommodation was induced by central stimulation of the Edinger-Westphal nucleus before and after intra- or extracapsular Lens extraction (ICLE, ECLE). Forward ciliary body movement and ciliary body width were measured by ultrasound biomicroscopy (UBM, 50 MHz). The monkeys were then killed, the eyes were examined morphologically in 1-microm sections, and the shape of the ciliary muscle was compared with that obtained from UBM images. RESULTS: The shape of the ciliary muscle in eyes undergoing ECLE (n = 5) did not differ from that in control eyes. In contrast, after ICLE (n = 10), accommodative forward ciliary body movement (P < 0.01) and thickness were decreased (P < 0.001), length was increased (P = 0.058), and the inner apex was located more Posteriorly than in control eyes (P < 0.005). Histologic and in vivo data were similar and showed that the ciliary muscle maintained its triangular shape only if the Lens Capsule (with or without the Lens substance) was present. CONCLUSIONS: The Posterior Lens Capsule and anterior zonular attachments facilitate forward accommodative ciliary body movement. Lens substance extraction procedures that leave the Posterior Capsule intact, similar to those used clinically, do not affect the Capsule/zonular/muscular system movements, an important finding for accommodating intraocular Lens development.
Paul L Kaufman - One of the best experts on this subject based on the ideXlab platform.
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Surgical intervention and accommodative responses, II: Forward ciliary body accommodative movement is facilitated by zonular attachments to the Lens Capsule. Invest Ophthalmol Vis Sci
2015Co-Authors: Rainer Wasilewski, Jared P Mcdonald, Paul L Kaufman, Gregg Heatley, Mary Ann CroftAbstract:PURPOSE. To determine the role of the Lens and the Lens Capsule in the three-dimensional architecture of the ciliary muscle at rest and during accommodation, in live rhesus monkeys and in histologic sections, by removing the entire Lens, or only the Lens nucleus and cortex, while leaving the Posterior Capsule in place. METHODS. In 15 rhesus monkey eyes, aged 6 to 27 years, accommodation was induced by central stimulation of the Edinger-Westphal nucleus before and after intra- or extracap-sular Lens extraction (ICLE, ECLE). Forward ciliary body move-ment and ciliary body width were measured by ultrasound biomicroscopy (UBM, 50 MHz). The monkeys were then killed, the eyes were examined morphologically in 1-m sections, and the shape of the ciliary muscle was compared with that ob-tained from UBM images. RESULTS. The shape of the ciliary muscle in eyes undergoing ECLE (n 5) did not differ from that in control eyes. In contrast, after ICLE (n 10), accommodative forward ciliary body movement (P 0.01) and thickness were decreased (P 0.001), length was increased (P 0.058), and the inner apex was located more Posteriorly than in control eyes (P 0.005). Histologic and in vivo data were similar and showed that the ciliary muscle maintained its triangular shape only if the Lens Capsule (with or without the Lens substance) was present. CONCLUSIONS. The Posterior Lens Capsule and anterior zonular attachments facilitate forward accommodative ciliary body movement. Lens substance extraction procedures that leave the Posterior Capsule intact, similar to those used clinically, do not affect the Capsule/zonular/muscular system move-ments, an important finding for accommodating intraocula
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surgical intervention and accommodative responses ii forward ciliary body accommodative movement is facilitated by zonular attachments to the Lens Capsule
Investigative Ophthalmology & Visual Science, 2008Co-Authors: Rainer Wasilewski, Jared P Mcdonald, Gregg A Heatley, Elke Lutjendrecoll, Paul L Kaufman, Mary Ann CroftAbstract:PURPOSE: To determine the role of the Lens and the Lens Capsule in the three-dimensional architecture of the ciliary muscle at rest and during accommodation, in live rhesus monkeys and in histologic sections, by removing the entire Lens, or only the Lens nucleus and cortex, while leaving the Posterior Capsule in place. METHODS: In 15 rhesus monkey eyes, aged 6 to 27 years, accommodation was induced by central stimulation of the Edinger-Westphal nucleus before and after intra- or extracapsular Lens extraction (ICLE, ECLE). Forward ciliary body movement and ciliary body width were measured by ultrasound biomicroscopy (UBM, 50 MHz). The monkeys were then killed, the eyes were examined morphologically in 1-microm sections, and the shape of the ciliary muscle was compared with that obtained from UBM images. RESULTS: The shape of the ciliary muscle in eyes undergoing ECLE (n = 5) did not differ from that in control eyes. In contrast, after ICLE (n = 10), accommodative forward ciliary body movement (P < 0.01) and thickness were decreased (P < 0.001), length was increased (P = 0.058), and the inner apex was located more Posteriorly than in control eyes (P < 0.005). Histologic and in vivo data were similar and showed that the ciliary muscle maintained its triangular shape only if the Lens Capsule (with or without the Lens substance) was present. CONCLUSIONS: The Posterior Lens Capsule and anterior zonular attachments facilitate forward accommodative ciliary body movement. Lens substance extraction procedures that leave the Posterior Capsule intact, similar to those used clinically, do not affect the Capsule/zonular/muscular system movements, an important finding for accommodating intraocular Lens development.
Walton Nosé - One of the best experts on this subject based on the ideXlab platform.
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rubeosis capsulare um caso incomum de rubeosis iridis em paciente com implante de lente intra ocular relato de caso
Arquivos Brasileiros De Oftalmologia, 2002Co-Authors: Alexandre Antonio Marques Rosa, Eduardo Cunha De Souza, Breno Barth, Walton NoséAbstract:The authors report a rare case of a diabetic patient with rubeosis iridis who had cataract extraction with intraocular Lens implantation, in whom neovascularization developed within the Posterior Lens Capsule.
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Rubeosis capsulare: um caso incomum de rubeosis iridis em paciente com implante de lente intra-ocular - Relato de caso Rubeosis capsulare: An unusual case of rubeosis iridis in a patient with Posterior intra-ocular Lens implantation - Case report
Conselho Brasileiro de Oftalmologia, 2002Co-Authors: Alexandre Marques A. Rosa, Eduardo Cunha De Souza, Breno Barth, Walton NoséAbstract:Os autores relatam o caso raro de paciente diabético com rubeosis iridis submetido à cirurgia de catarata com implante de lente intra-ocular, em que houve o crescimento de neovasos na cápsula Posterior do cristalino.The authors report a rare case of a diabetic patient with rubeosis iridis who had cataract extraction with intraocular Lens implantation, in whom neovascularization developed within the Posterior Lens Capsule
Onur Çatak - One of the best experts on this subject based on the ideXlab platform.
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Annular and central heavy pigment deposition on the Posterior Lens Capsule in the pigment dispersion syndrome: pigment deposition on the Posterior Lens Capsule in the pigment dispersion syndrome.
International ophthalmology, 2007Co-Authors: Burak Turgut, Peykan Türkçüoğlu, Nurettin Deniz, Onur ÇatakAbstract:Purpose To report annular and central heavy pigment deposition on the Posterior Lens Capsule in a case of pigment dispersion syndrome. Methods Case report. Results A 36-year-old female with bilateral pigment dispersion syndrome presented with progressive decrease in visual acuity in the right eye over the past 1–2 years. Clinical examination revealed the typical findings of pigment dispersion syndrome including bilateral Krunkenberg spindles, iris transillumination defects, and dense trabecular meshwork pigmentation. Remarkably, annular and central dense pigmentation of the Posterior Lens Capsule was noted in the right eye. Conclusion Annular pigment deposition on the Posterior Lens Capsule may be a rare finding associated with pigment dispersion syndrome. Such a finding suggests that there may be aqueous flow into the retrolental space in some patients with this condition. The way of central pigmentation is the entrance of aqueous to Berger’s space. In our case, it is probable that spontaneous detachment of the anterior hyaloid membrane aided this entrance.
K. Singh - One of the best experts on this subject based on the ideXlab platform.
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Dense pigmentation of the Posterior Lens Capsule associated with the pigment dispersion syndrome
J Glaucoma, 2003Co-Authors: D.y. Lin, M Volpicelli, K. SinghAbstract:PURPOSE: To report an unusual case of pigment dispersion syndrome associated with unilateral dense pigmentation of the Posterior Lens Capsule. METHODS: Case report. RESULTS: A 59-year-old male with bilateral pigment dispersion syndrome presented with progressive decrease in visual acuity in the left eye over the past 10 to 20 years. Clinical examination revealed the typical findings of pigment dispersion syndrome including the presence of bilateral Krunkenberg spindles, iris transillumination defects, and heavy trabecular meshwork pigmentation. Of note, there was remarkably dense pigmentation of the Posterior Lens Capsule in the eye with decreased visual acuity. CONCLUSION: Pigmentation of the Posterior Lens Capsule may be a rare finding associated with pigment dispersion syndrome. Such a finding suggests that there may be aqueous flow into the retrolental space in some patients with this condition. The optimal treatment of this unusual condition remains undetermined.
