The Experts below are selected from a list of 1668 Experts worldwide ranked by ideXlab platform

Chengyuan Wang - One of the best experts on this subject based on the ideXlab platform.

  • Atomistic Modeling of F‑Actin Mechanical Responses and Determination of Mechanical Properties
    2018
    Co-Authors: Jin Zhang, Chengyuan Wang, Perumal Nithiarasu
    Abstract:

    A molecular structural mechanics (MSM) model was developed for F-actins in cells, where the force constants describing the monomer interaction were achieved using molecular dynamics simulations. The MSM was then employed to predict the mechanical properties of F-actin. The obtained Young’s modulus (1.92 GPa), torsional rigidity (2.36 × 10–26 Nm2), and flexural rigidity (10.84 × 10–26 Nm2) were found to be in good agreement with existing experimental data. Subsequently, the tension-induced bending was studied for F-actins as a result of their helical structure. Mechanical instability was also investigated for the actin filaments in filopodial protrusion by considering the reinforcing effect of the actin-binding proteins. The Predicted Buckling Load agreed well with the experimentally obtained stall force, showing a pivotal role of the actin-binding protein in regulating the stiffness of F-actin bundles during the formation of filopodia protrusion. Herein, it is expected that the MSM model can be extended to the mechanics of more complex filamentous systems such as stress fibers and actin meshwork

  • Atomistic Modeling of F-Actin Mechanical Responses and Determination of Mechanical Properties
    2018
    Co-Authors: Chengyuan Wang
    Abstract:

    A molecular structural mechanics (MSM) model was developed for F-actins in cells, where the force constants describing the monomer interaction were achieved using molecular dynamics simulations. The MSM was then employed to predict the mechanical properties of F-actin. The obtained Young’s modulus (1.92 GPa), torsional rigidity (2.36 × 10–26 Nm2), and flexural rigidity (10.84 × 10–26 Nm2) were found to be in good agreement with existing experimental data. Subsequently, the tension-induced bending was studied for F-actins as a result of their helical structure. Mechanical instability was also investigated for the actin filaments in filopodial protrusion by considering the reinforcing effect of the actin-binding proteins. The Predicted Buckling Load agreed well with the experimentally obtained stall force, showing a pivotal role of the actin-binding protein in regulating the stiffness of F-actin bundles during the formation of filopodia protrusion. Herein, it is expected that the MSM model can be extended to the mechanics of more complex filamentous systems such as stress fibers and actin meshwork

Perumal Nithiarasu - One of the best experts on this subject based on the ideXlab platform.

  • Atomistic Modeling of F‑Actin Mechanical Responses and Determination of Mechanical Properties
    2018
    Co-Authors: Jin Zhang, Chengyuan Wang, Perumal Nithiarasu
    Abstract:

    A molecular structural mechanics (MSM) model was developed for F-actins in cells, where the force constants describing the monomer interaction were achieved using molecular dynamics simulations. The MSM was then employed to predict the mechanical properties of F-actin. The obtained Young’s modulus (1.92 GPa), torsional rigidity (2.36 × 10–26 Nm2), and flexural rigidity (10.84 × 10–26 Nm2) were found to be in good agreement with existing experimental data. Subsequently, the tension-induced bending was studied for F-actins as a result of their helical structure. Mechanical instability was also investigated for the actin filaments in filopodial protrusion by considering the reinforcing effect of the actin-binding proteins. The Predicted Buckling Load agreed well with the experimentally obtained stall force, showing a pivotal role of the actin-binding protein in regulating the stiffness of F-actin bundles during the formation of filopodia protrusion. Herein, it is expected that the MSM model can be extended to the mechanics of more complex filamentous systems such as stress fibers and actin meshwork

Jin Zhang - One of the best experts on this subject based on the ideXlab platform.

  • Atomistic Modeling of F‑Actin Mechanical Responses and Determination of Mechanical Properties
    2018
    Co-Authors: Jin Zhang, Chengyuan Wang, Perumal Nithiarasu
    Abstract:

    A molecular structural mechanics (MSM) model was developed for F-actins in cells, where the force constants describing the monomer interaction were achieved using molecular dynamics simulations. The MSM was then employed to predict the mechanical properties of F-actin. The obtained Young’s modulus (1.92 GPa), torsional rigidity (2.36 × 10–26 Nm2), and flexural rigidity (10.84 × 10–26 Nm2) were found to be in good agreement with existing experimental data. Subsequently, the tension-induced bending was studied for F-actins as a result of their helical structure. Mechanical instability was also investigated for the actin filaments in filopodial protrusion by considering the reinforcing effect of the actin-binding proteins. The Predicted Buckling Load agreed well with the experimentally obtained stall force, showing a pivotal role of the actin-binding protein in regulating the stiffness of F-actin bundles during the formation of filopodia protrusion. Herein, it is expected that the MSM model can be extended to the mechanics of more complex filamentous systems such as stress fibers and actin meshwork

Hyungjoon Bang - One of the best experts on this subject based on the ideXlab platform.

  • a study on the prediction of lateral Buckling Load for wind turbine tower structures
    2012
    Co-Authors: Kangsu Lee, Hyungjoon Bang
    Abstract:

    A method to evaluate the structural safety of lateral Buckling Load is presented, using FEM analysis for a wind turbine tower with a thin circular wall. Europe, the U.S., and Japan already have long histories of research into wind power due to its high efficiency. The tower structure that supports a wind turbine is one important research area. There are three types of tower that vary by structural composition: a cylindrical tower with a circular cross-section, a jacket tower with a truss structure, and a hybrid tower. This paper investigates an accident involving a 600kW wind turbine that occurred in JeJu, Korea in October of 2010. The results from a numerical analysis are compared with the actual collapse mode observed at the accident. Some Buckling modes and wind speeds at which non-linear Buckling response occurs are Predicted via the arclength method for a land-based cylindrical stationary tower. The evaluation method is used accident (experiment), analytical, linear and nonlinear finite element method (beam and shell) to analyze the result of Predicted Buckling Load of tower. The result of nonlinear FEM shell model was found to exhibit similar behavior to the accident situation during Buckling. It is concluded that this paper provides Buckling analysis process and method used for the slender shell structures: the Predicted Buckling Load and analysis methodology. In this paper, The results from the numerical estimation show good agreement with those of the analytical calculation, indicating that the arc-length method effectively improved the convergence. We found out Buckling limit Load of the accident wind turbine tower and wind speed at Buckling point. The result of nonlinear FEM shell model was found to exhibit similar behavior to the actual accident (experiment) situation during Buckling. The presented Buckling evaluation method will be useful for both static design and dynamic performance evaluation of land-based wind turbines, as well as sea-based wind turbines.

Hayden O. Griffin - One of the best experts on this subject based on the ideXlab platform.

  • Finite Element Predictions of Active Buckling Control of Stiffened Panels
    2016
    Co-Authors: Danniella Muheim, Hayden O. Griffin
    Abstract:

    ABSTRACT: Materials systems and structures that can respond "intelligently " to their environment are currently being proposed and investigated. A series of finite element analyses was performed to investigate the potential for active Buckling control of two different stiffened panels by embedded shape memory alloy (SMA) rods. Changes in the Predicted Buckling Load increased with the magni-tude of the actuation level for a given structural concept. Increasing the number of actuators for a given concept yielded greater Predicted increases in Buckling Load. Considerable control authority was generated with a small number of actuators, with greater authority demonstrated for those struc-tural concepts where the activated SMA rods could develop greater forces and moments on the struc-ture. Relatively simple and inexpensive analyses were performed with standard finite elements to de-termine such information, indicating the viability of these types of models for design purposes