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Bertrand Guillonneau - One of the best experts on this subject based on the ideXlab platform.
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standard versus limited pelvic lymph node dissection for prostate cancer in patients with a Predicted Probability of nodal metastasis greater than 1
The Journal of Urology, 2007Co-Authors: Karim Touijer, Farhang Rabbani, Javier Romero Otero, Fernando P Secin, James A Eastham, Peter T Scardino, Bertrand GuillonneauAbstract:Purpose: We determined the yield of standard vs limited pelvic lymphadenectomy in patients with a Predicted risk of lymph node metastasis greater than 1% according to the Partin tables Predicted Probability of pathological stage. We also determined the feasibility of laparoscopic standard pelvic lymph node dissection.Materials and Methods: Of 1,269 patients with clinically localized prostate cancer undergoing radical prostatectomy, 648 had a Partin’s table Predicted Probability of lymph node invasion greater than 1%. Of the 648 patients 177 underwent limited pelvic lymph node dissection performed laparoscopically (group 1), and 471 underwent standard pelvic lymph node dissection performed open (367) or laparoscopically (104) (group 2). Templates of limited pelvic lymph node dissection included the external iliac lymph nodes whereas standard pelvic lymph node dissection included the external iliac, obturator and hypogastric lymph nodes. Multivariate logistic regression analyses were performed to compare th...
Christopher J. Kane - One of the best experts on this subject based on the ideXlab platform.
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Standard versus limited pelvic lymph node dissection for prostate cancer in patients with a Predicted Probability of nodal metastasis greater than 1
Urologic Oncology: Seminars and Original Investigations, 2008Co-Authors: Christopher J. KaneAbstract:Purpose We determined the yield of standard vs limited pelvic lymphadenectomy in patients with a Predicted risk of lymph node metastasis greater than 1% according to the Partin tables Predicted Probability of pathological stage. We also determined the feasibility of laparoscopic standard pelvic lymph node dissection. Materials and Methods Of 1,269 patients with clinically localized prostate cancer undergoing radical prostatectomy, 648 had a Partin table Predicted Probability of lymph node invasion greater than 1%. Of the 648 patients, 177 underwent limited pelvic lymph node dissection performed laparoscopically (Group 1), and 471 underwent standard pelvic lymph node dissection performed open (367) or laparoscopically (104) (Group 2). Templates of limited pelvic lymph node dissection included the external iliac lymph nodes whereas standard pelvic lymph node dissection included the external iliac, obturator and hypogastric lymph nodes. Multivariate logistic regression analyses were performed to compare the node positivity rate between Groups 1 and 2. Results On multivariate logistic regression analysis controlling for prostate specific antigen, biopsy Gleason sum, clinical stage and surgical approach, the odds of node positivity were 7.15-fold higher (95% CI 2.49–20.5, P P P Conclusions Standard lymph node dissection yields positive nodes more frequently and retrieves a higher total nodal count than the often performed pelvic lymph node dissection limited to the external iliac nodes. Standard pelvic lymph node dissection is feasible through a transperitoneal laparoscopic approach.
Karim Touijer - One of the best experts on this subject based on the ideXlab platform.
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standard versus limited pelvic lymph node dissection for prostate cancer in patients with a Predicted Probability of nodal metastasis greater than 1
The Journal of Urology, 2007Co-Authors: Karim Touijer, Farhang Rabbani, Javier Romero Otero, Fernando P Secin, James A Eastham, Peter T Scardino, Bertrand GuillonneauAbstract:Purpose: We determined the yield of standard vs limited pelvic lymphadenectomy in patients with a Predicted risk of lymph node metastasis greater than 1% according to the Partin tables Predicted Probability of pathological stage. We also determined the feasibility of laparoscopic standard pelvic lymph node dissection.Materials and Methods: Of 1,269 patients with clinically localized prostate cancer undergoing radical prostatectomy, 648 had a Partin’s table Predicted Probability of lymph node invasion greater than 1%. Of the 648 patients 177 underwent limited pelvic lymph node dissection performed laparoscopically (group 1), and 471 underwent standard pelvic lymph node dissection performed open (367) or laparoscopically (104) (group 2). Templates of limited pelvic lymph node dissection included the external iliac lymph nodes whereas standard pelvic lymph node dissection included the external iliac, obturator and hypogastric lymph nodes. Multivariate logistic regression analyses were performed to compare th...
Fernando P Secin - One of the best experts on this subject based on the ideXlab platform.
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standard versus limited pelvic lymph node dissection for prostate cancer in patients with a Predicted Probability of nodal metastasis greater than 1
The Journal of Urology, 2007Co-Authors: Karim Touijer, Farhang Rabbani, Javier Romero Otero, Fernando P Secin, James A Eastham, Peter T Scardino, Bertrand GuillonneauAbstract:Purpose: We determined the yield of standard vs limited pelvic lymphadenectomy in patients with a Predicted risk of lymph node metastasis greater than 1% according to the Partin tables Predicted Probability of pathological stage. We also determined the feasibility of laparoscopic standard pelvic lymph node dissection.Materials and Methods: Of 1,269 patients with clinically localized prostate cancer undergoing radical prostatectomy, 648 had a Partin’s table Predicted Probability of lymph node invasion greater than 1%. Of the 648 patients 177 underwent limited pelvic lymph node dissection performed laparoscopically (group 1), and 471 underwent standard pelvic lymph node dissection performed open (367) or laparoscopically (104) (group 2). Templates of limited pelvic lymph node dissection included the external iliac lymph nodes whereas standard pelvic lymph node dissection included the external iliac, obturator and hypogastric lymph nodes. Multivariate logistic regression analyses were performed to compare th...
Peter T Scardino - One of the best experts on this subject based on the ideXlab platform.
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standard versus limited pelvic lymph node dissection for prostate cancer in patients with a Predicted Probability of nodal metastasis greater than 1
The Journal of Urology, 2007Co-Authors: Karim Touijer, Farhang Rabbani, Javier Romero Otero, Fernando P Secin, James A Eastham, Peter T Scardino, Bertrand GuillonneauAbstract:Purpose: We determined the yield of standard vs limited pelvic lymphadenectomy in patients with a Predicted risk of lymph node metastasis greater than 1% according to the Partin tables Predicted Probability of pathological stage. We also determined the feasibility of laparoscopic standard pelvic lymph node dissection.Materials and Methods: Of 1,269 patients with clinically localized prostate cancer undergoing radical prostatectomy, 648 had a Partin’s table Predicted Probability of lymph node invasion greater than 1%. Of the 648 patients 177 underwent limited pelvic lymph node dissection performed laparoscopically (group 1), and 471 underwent standard pelvic lymph node dissection performed open (367) or laparoscopically (104) (group 2). Templates of limited pelvic lymph node dissection included the external iliac lymph nodes whereas standard pelvic lymph node dissection included the external iliac, obturator and hypogastric lymph nodes. Multivariate logistic regression analyses were performed to compare th...