The Experts below are selected from a list of 129 Experts worldwide ranked by ideXlab platform
Roger Berg - One of the best experts on this subject based on the ideXlab platform.
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connected commercial vehicles retrofit safety device kit project safety applications and development plan
2014Co-Authors: Bryan Wells, Roger BergAbstract:Connected vehicle wireless data communications can enable safety applications that may reduce injuries and fatalities. Cooperative vehicle-to-vehicle (V2V) safety applications will be effective only if a high fraction of vehicles are equipped. Deployment of V2V technology will be enhanced if it is available not only for manufacturing in new vehicles but also for retrofit to existing vehicles. The objective of the Connected Commercial Vehicles—Retrofit Safety Device (CCV-RSD) Kit Project was to develop complete hardware and software that can be used in various brands and models of heavy trucks. The RSD kits provide the functionality needed for cooperative V2V and vehicle-to-infrastructure (V2I) safety applications to support the Model Deployment and other USDOT connected vehicle projects. This project included testing and documentation needed for installation, operation, enhancement, and maintenance of the units. These retrofit kits were built so they could be installed in existing class 6, 7, or 8 trucks. The RSD kits achieved a V2V and V2I functionality similar to that of the Connected Commercial Vehicles—Integrated Truck (CCV-IT) vehicles, where onboard equipment was integrated with newly manufactured truck tractors. This document describes application requirements for CCV-RSD safety applications, including Forward Collision Warning (FCW), Intersection Movement Assist (IMA), Blind Spot Warning (BSW), Emergency Electronic Brake Lights (EEBL), and Curve Speed Warning (CSW). Safety applications based on these requirements were subsequently implemented in the CCV-RSD program as an adaptation of a Preexisting System developed for Light Vehicles and the CCV-IT program.
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Connected commercial vehicles — retrofit safety device kit project : safety applications and development plan.
2014Co-Authors: Bryan Wells, Roger BergAbstract:Connected vehicle wireless data communications can enable safety applications that may reduce injuries and fatalities. Cooperative vehicle-to-vehicle (V2V) safety applications will be effective only if a high fraction of vehicles are equipped. Deployment of V2V technology will be enhanced if it is available not only for manufacturing in new vehicles but also for retrofit to existing vehicles. The objective of the Connected Commercial Vehicles—Retrofit Safety Device (CCV-RSD) Kit Project was to develop complete hardware and software that can be used in various brands and models of heavy trucks. The RSD kits provide the functionality needed for cooperative V2V and vehicle-to-infrastructure (V2I) safety applications to support the Model Deployment and other USDOT connected vehicle projects. This project included testing and documentation needed for installation, operation, enhancement, and maintenance of the units. These retrofit kits were built so they could be installed in existing class 6, 7, or 8 trucks. The RSD kits achieved a V2V and V2I functionality similar to that of the Connected Commercial Vehicles—Integrated Truck (CCV-IT) vehicles, where onboard equipment was integrated with newly manufactured truck tractors. This document describes application requirements for CCV-RSD safety applications, including Forward Collision Warning (FCW), Intersection Movement Assist (IMA), Blind Spot Warning (BSW), Emergency Electronic Brake Lights (EEBL), and Curve Speed Warning (CSW). Safety applications based on these requirements were subsequently implemented in the CCV-RSD program as an adaptation of a Preexisting System developed for Light Vehicles and the CCV-IT program.
Marçal Pastor-anglada - One of the best experts on this subject based on the ideXlab platform.
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Cytoskeletal‐dependent activation of System A for neutral amino acid transport in osmotically stressed mammalian cells: A role for System A in the intracellular accumulation of osmolytes
Journal of cellular physiology, 1997Co-Authors: M. Gomez-angelats, Marta López-fontanals, Antonio Felipe, F J Casado, Marçal Pastor-angladaAbstract:System A activity for neutral amino acid transport is increased after hypertonic shock in NBL-1 (an epithelial cell line) and CHO-K1 cells (a nonepithelial cell line) by a mechanism which is consistent with the synthesis of a regulatory protein that activates Preexisting System A carrier proteins (Ruiz-Montasell et al., 1994, Proc. Natl. Acad. Sci. USA, 91,9569-9573). In this study, we have further investigated this biological response by determining the role of cytoskeletal structures in System A regulation by hypertonic stress. Using inhibitors of the microfilament and microtubule networks, we show that the increase in System A activity after hypertonic treatment requires the integrity of both cytoskeletal structures in NBL-1 cells, although the increase in System A activity triggered by amino acid starvation is completely insensitive to any of these drugs. In contrast, the enhancement of System A activity in osmotically stressed CHO-K1 cells is not sensitive to inhibitors of the microtubule network. In both cell types, the results suggest that the inhibitors block the increase of System A activity. System A transport decreases when CHO-K1 cells return to isotonic conditions by a mechanism that is insensitive to inhibitors of protein and mRNA synthesis. The increase in System A transport activity is also followed by the accumulation of neutral amino acids (fourfold for alanine), which is totally blocked by the same agents (cycloheximide and actinomycin D) that prevent the increase in System A activity after hypertonic treatment, thus indicating that System A is crucial for maintaining a high concentration of organic osmolytes inside the cell.
Bryan Wells - One of the best experts on this subject based on the ideXlab platform.
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connected commercial vehicles retrofit safety device kit project safety applications and development plan
2014Co-Authors: Bryan Wells, Roger BergAbstract:Connected vehicle wireless data communications can enable safety applications that may reduce injuries and fatalities. Cooperative vehicle-to-vehicle (V2V) safety applications will be effective only if a high fraction of vehicles are equipped. Deployment of V2V technology will be enhanced if it is available not only for manufacturing in new vehicles but also for retrofit to existing vehicles. The objective of the Connected Commercial Vehicles—Retrofit Safety Device (CCV-RSD) Kit Project was to develop complete hardware and software that can be used in various brands and models of heavy trucks. The RSD kits provide the functionality needed for cooperative V2V and vehicle-to-infrastructure (V2I) safety applications to support the Model Deployment and other USDOT connected vehicle projects. This project included testing and documentation needed for installation, operation, enhancement, and maintenance of the units. These retrofit kits were built so they could be installed in existing class 6, 7, or 8 trucks. The RSD kits achieved a V2V and V2I functionality similar to that of the Connected Commercial Vehicles—Integrated Truck (CCV-IT) vehicles, where onboard equipment was integrated with newly manufactured truck tractors. This document describes application requirements for CCV-RSD safety applications, including Forward Collision Warning (FCW), Intersection Movement Assist (IMA), Blind Spot Warning (BSW), Emergency Electronic Brake Lights (EEBL), and Curve Speed Warning (CSW). Safety applications based on these requirements were subsequently implemented in the CCV-RSD program as an adaptation of a Preexisting System developed for Light Vehicles and the CCV-IT program.
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Connected commercial vehicles — retrofit safety device kit project : safety applications and development plan.
2014Co-Authors: Bryan Wells, Roger BergAbstract:Connected vehicle wireless data communications can enable safety applications that may reduce injuries and fatalities. Cooperative vehicle-to-vehicle (V2V) safety applications will be effective only if a high fraction of vehicles are equipped. Deployment of V2V technology will be enhanced if it is available not only for manufacturing in new vehicles but also for retrofit to existing vehicles. The objective of the Connected Commercial Vehicles—Retrofit Safety Device (CCV-RSD) Kit Project was to develop complete hardware and software that can be used in various brands and models of heavy trucks. The RSD kits provide the functionality needed for cooperative V2V and vehicle-to-infrastructure (V2I) safety applications to support the Model Deployment and other USDOT connected vehicle projects. This project included testing and documentation needed for installation, operation, enhancement, and maintenance of the units. These retrofit kits were built so they could be installed in existing class 6, 7, or 8 trucks. The RSD kits achieved a V2V and V2I functionality similar to that of the Connected Commercial Vehicles—Integrated Truck (CCV-IT) vehicles, where onboard equipment was integrated with newly manufactured truck tractors. This document describes application requirements for CCV-RSD safety applications, including Forward Collision Warning (FCW), Intersection Movement Assist (IMA), Blind Spot Warning (BSW), Emergency Electronic Brake Lights (EEBL), and Curve Speed Warning (CSW). Safety applications based on these requirements were subsequently implemented in the CCV-RSD program as an adaptation of a Preexisting System developed for Light Vehicles and the CCV-IT program.
A Aprile - One of the best experts on this subject based on the ideXlab platform.
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INTEGRATING LOW-FLOOR TECHNOLOGY INTO A Preexisting INFRASTRUCTURE: PARTIAL LOW-FLOOR LIGHT RAIL VEHICLE IN A MIXED ENVIRONMENT: LESSONS LEARNED FROM THE MANUFACTURE OF BOSTON'S PARTIAL LOW-FLOOR LIGHT RAIL VEHICLE
2000Co-Authors: M Marianeschi, A Bandinelli, A AprileAbstract:The Massachusetts Bay Transportation Authority (MBTA) has started the revenue service of its No. 8 partial low-floor light rail vehicles (LRV) manufactured by Breda Costruzioni Ferroviarie S.p.A. of Italy. The MBTA encompasses one of the most difficult operating environments in North America. Breda had to adopt and implement unique design solutions. An update of the Boston project is provided, as is an exploration of the key challenges inherent in designing a partial low-floor LRV for a Preexisting System with high-floor vehicles. Breda's approach in addressing static and dynamic compatibility issues between partial low-floor and high-floor vehicles is presented. Proactively controlling technical risk is among the lessons that may be learned from Breda's experience.
M. Gomez-angelats - One of the best experts on this subject based on the ideXlab platform.
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Cytoskeletal‐dependent activation of System A for neutral amino acid transport in osmotically stressed mammalian cells: A role for System A in the intracellular accumulation of osmolytes
Journal of cellular physiology, 1997Co-Authors: M. Gomez-angelats, Marta López-fontanals, Antonio Felipe, F J Casado, Marçal Pastor-angladaAbstract:System A activity for neutral amino acid transport is increased after hypertonic shock in NBL-1 (an epithelial cell line) and CHO-K1 cells (a nonepithelial cell line) by a mechanism which is consistent with the synthesis of a regulatory protein that activates Preexisting System A carrier proteins (Ruiz-Montasell et al., 1994, Proc. Natl. Acad. Sci. USA, 91,9569-9573). In this study, we have further investigated this biological response by determining the role of cytoskeletal structures in System A regulation by hypertonic stress. Using inhibitors of the microfilament and microtubule networks, we show that the increase in System A activity after hypertonic treatment requires the integrity of both cytoskeletal structures in NBL-1 cells, although the increase in System A activity triggered by amino acid starvation is completely insensitive to any of these drugs. In contrast, the enhancement of System A activity in osmotically stressed CHO-K1 cells is not sensitive to inhibitors of the microtubule network. In both cell types, the results suggest that the inhibitors block the increase of System A activity. System A transport decreases when CHO-K1 cells return to isotonic conditions by a mechanism that is insensitive to inhibitors of protein and mRNA synthesis. The increase in System A transport activity is also followed by the accumulation of neutral amino acids (fourfold for alanine), which is totally blocked by the same agents (cycloheximide and actinomycin D) that prevent the increase in System A activity after hypertonic treatment, thus indicating that System A is crucial for maintaining a high concentration of organic osmolytes inside the cell.