The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform

Alvaro Alonso - One of the best experts on this subject based on the ideXlab platform.

  • Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community
    Journal of the American Heart Association, 2017
    Co-Authors: Kaylin T. Nguyen, Eric Vittinghoff, Thomas A. Dewland, Jonathan W. Dukes, Elsayed Z. Soliman, Phyllis K. Stein, John S. Gottdiener, Alvaro Alonso, Lin Y. Chen, Bruce M. Psaty
    Abstract:

    Background Atrial fibrillation and heart failure are 2 of the most common diseases, yet ready means to identify individuals at risk are lacking. The 12‐lead ECG is one of the most accessible tests in medicine. Our objective was to determine whether a Premature Atrial Contraction observed on a standard 12‐lead ECG would predict Atrial fibrillation and mortality and whether a Premature ventricular Contraction would predict heart failure and mortality. Methods and Results We utilized the CHS (Cardiovascular Health) Study, which followed 5577 participants for a median of 12 years, as the primary cohort. The ARIC (Atherosclerosis Risk in Communities Study), the replication cohort, captured data from 15 792 participants over a median of 22 years. In the CHS, multivariable analyses revealed that a baseline 12‐lead ECG Premature Atrial Contraction predicted a 60% increased risk of Atrial fibrillation (hazard ratio, 1.6; 95% CI, 1.3–2.0; P P =0.021). In the negative control analyses, neither predicted incident myocardial infarction. A Premature Atrial Contraction was associated with a 30% increased risk of death (hazard ratio, 1.3; 95% CI, 1.1–1.5; P =0.008) and a Premature ventricular Contraction was associated with a 20% increased risk of death (hazard ratio, 1.2; 95% CI, 1.0–1.3; P =0.044). Similarly statistically significant results for each analysis were also observed in ARIC. Conclusions Based on a single standard ECG, a Premature Atrial Contraction predicted incident Atrial fibrillation and death and a Premature ventricular Contraction predicted incident heart failure and death, suggesting that this commonly used test may predict future disease.

  • Abstract 11724: Premature Atrial Contraction Frequency is not Associated With Cerebral Infarcts: The Atherosclerosis Risk in Communities (ARIC) Study
    Circulation, 2015
    Co-Authors: Lin Y. Chen, Elsayed Z. Soliman, Sunil K. Agarwal, Faye L. Norby, Rebecca F. Gottesman, Laura R. Loehr, Thomas H. Mosley, Aaron R. Folsom, Josef Coresh, Alvaro Alonso
    Abstract:

    Background: Premature Atrial Contractions (PACs) have been shown to predict incident Atrial fibrillation (AF). However, the association between PAC frequency and risk of ischemic stroke is less wel...

Bruce M. Psaty - One of the best experts on this subject based on the ideXlab platform.

  • Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community
    Journal of the American Heart Association, 2017
    Co-Authors: Kaylin T. Nguyen, Eric Vittinghoff, Thomas A. Dewland, Jonathan W. Dukes, Elsayed Z. Soliman, Phyllis K. Stein, John S. Gottdiener, Alvaro Alonso, Lin Y. Chen, Bruce M. Psaty
    Abstract:

    Background Atrial fibrillation and heart failure are 2 of the most common diseases, yet ready means to identify individuals at risk are lacking. The 12‐lead ECG is one of the most accessible tests in medicine. Our objective was to determine whether a Premature Atrial Contraction observed on a standard 12‐lead ECG would predict Atrial fibrillation and mortality and whether a Premature ventricular Contraction would predict heart failure and mortality. Methods and Results We utilized the CHS (Cardiovascular Health) Study, which followed 5577 participants for a median of 12 years, as the primary cohort. The ARIC (Atherosclerosis Risk in Communities Study), the replication cohort, captured data from 15 792 participants over a median of 22 years. In the CHS, multivariable analyses revealed that a baseline 12‐lead ECG Premature Atrial Contraction predicted a 60% increased risk of Atrial fibrillation (hazard ratio, 1.6; 95% CI, 1.3–2.0; P P =0.021). In the negative control analyses, neither predicted incident myocardial infarction. A Premature Atrial Contraction was associated with a 30% increased risk of death (hazard ratio, 1.3; 95% CI, 1.1–1.5; P =0.008) and a Premature ventricular Contraction was associated with a 20% increased risk of death (hazard ratio, 1.2; 95% CI, 1.0–1.3; P =0.044). Similarly statistically significant results for each analysis were also observed in ARIC. Conclusions Based on a single standard ECG, a Premature Atrial Contraction predicted incident Atrial fibrillation and death and a Premature ventricular Contraction predicted incident heart failure and death, suggesting that this commonly used test may predict future disease.

Lin Y. Chen - One of the best experts on this subject based on the ideXlab platform.

  • Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community
    Journal of the American Heart Association, 2017
    Co-Authors: Kaylin T. Nguyen, Eric Vittinghoff, Thomas A. Dewland, Jonathan W. Dukes, Elsayed Z. Soliman, Phyllis K. Stein, John S. Gottdiener, Alvaro Alonso, Lin Y. Chen, Bruce M. Psaty
    Abstract:

    Background Atrial fibrillation and heart failure are 2 of the most common diseases, yet ready means to identify individuals at risk are lacking. The 12‐lead ECG is one of the most accessible tests in medicine. Our objective was to determine whether a Premature Atrial Contraction observed on a standard 12‐lead ECG would predict Atrial fibrillation and mortality and whether a Premature ventricular Contraction would predict heart failure and mortality. Methods and Results We utilized the CHS (Cardiovascular Health) Study, which followed 5577 participants for a median of 12 years, as the primary cohort. The ARIC (Atherosclerosis Risk in Communities Study), the replication cohort, captured data from 15 792 participants over a median of 22 years. In the CHS, multivariable analyses revealed that a baseline 12‐lead ECG Premature Atrial Contraction predicted a 60% increased risk of Atrial fibrillation (hazard ratio, 1.6; 95% CI, 1.3–2.0; P P =0.021). In the negative control analyses, neither predicted incident myocardial infarction. A Premature Atrial Contraction was associated with a 30% increased risk of death (hazard ratio, 1.3; 95% CI, 1.1–1.5; P =0.008) and a Premature ventricular Contraction was associated with a 20% increased risk of death (hazard ratio, 1.2; 95% CI, 1.0–1.3; P =0.044). Similarly statistically significant results for each analysis were also observed in ARIC. Conclusions Based on a single standard ECG, a Premature Atrial Contraction predicted incident Atrial fibrillation and death and a Premature ventricular Contraction predicted incident heart failure and death, suggesting that this commonly used test may predict future disease.

  • Abstract 11724: Premature Atrial Contraction Frequency is not Associated With Cerebral Infarcts: The Atherosclerosis Risk in Communities (ARIC) Study
    Circulation, 2015
    Co-Authors: Lin Y. Chen, Elsayed Z. Soliman, Sunil K. Agarwal, Faye L. Norby, Rebecca F. Gottesman, Laura R. Loehr, Thomas H. Mosley, Aaron R. Folsom, Josef Coresh, Alvaro Alonso
    Abstract:

    Background: Premature Atrial Contractions (PACs) have been shown to predict incident Atrial fibrillation (AF). However, the association between PAC frequency and risk of ischemic stroke is less wel...

Elsayed Z. Soliman - One of the best experts on this subject based on the ideXlab platform.

  • Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community
    Journal of the American Heart Association, 2017
    Co-Authors: Kaylin T. Nguyen, Eric Vittinghoff, Thomas A. Dewland, Jonathan W. Dukes, Elsayed Z. Soliman, Phyllis K. Stein, John S. Gottdiener, Alvaro Alonso, Lin Y. Chen, Bruce M. Psaty
    Abstract:

    Background Atrial fibrillation and heart failure are 2 of the most common diseases, yet ready means to identify individuals at risk are lacking. The 12‐lead ECG is one of the most accessible tests in medicine. Our objective was to determine whether a Premature Atrial Contraction observed on a standard 12‐lead ECG would predict Atrial fibrillation and mortality and whether a Premature ventricular Contraction would predict heart failure and mortality. Methods and Results We utilized the CHS (Cardiovascular Health) Study, which followed 5577 participants for a median of 12 years, as the primary cohort. The ARIC (Atherosclerosis Risk in Communities Study), the replication cohort, captured data from 15 792 participants over a median of 22 years. In the CHS, multivariable analyses revealed that a baseline 12‐lead ECG Premature Atrial Contraction predicted a 60% increased risk of Atrial fibrillation (hazard ratio, 1.6; 95% CI, 1.3–2.0; P P =0.021). In the negative control analyses, neither predicted incident myocardial infarction. A Premature Atrial Contraction was associated with a 30% increased risk of death (hazard ratio, 1.3; 95% CI, 1.1–1.5; P =0.008) and a Premature ventricular Contraction was associated with a 20% increased risk of death (hazard ratio, 1.2; 95% CI, 1.0–1.3; P =0.044). Similarly statistically significant results for each analysis were also observed in ARIC. Conclusions Based on a single standard ECG, a Premature Atrial Contraction predicted incident Atrial fibrillation and death and a Premature ventricular Contraction predicted incident heart failure and death, suggesting that this commonly used test may predict future disease.

  • Abstract 11724: Premature Atrial Contraction Frequency is not Associated With Cerebral Infarcts: The Atherosclerosis Risk in Communities (ARIC) Study
    Circulation, 2015
    Co-Authors: Lin Y. Chen, Elsayed Z. Soliman, Sunil K. Agarwal, Faye L. Norby, Rebecca F. Gottesman, Laura R. Loehr, Thomas H. Mosley, Aaron R. Folsom, Josef Coresh, Alvaro Alonso
    Abstract:

    Background: Premature Atrial Contractions (PACs) have been shown to predict incident Atrial fibrillation (AF). However, the association between PAC frequency and risk of ischemic stroke is less wel...

Yasushi Koyama - One of the best experts on this subject based on the ideXlab platform.

  • burden and long firing of Premature Atrial Contraction early after catheter ablation predict late recurrence of Atrial fibrillation
    Circulation, 2020
    Co-Authors: Hiroyuki Inoue, Nobuaki Tanaka, Koji Tanaka, Yuichi Ninomiya, Yuko Hirao, Takafumi Oka, Masato Okada, Ryo Kitagaki, Kohtaro Takayasu, Yasushi Koyama
    Abstract:

    BACKGROUND Associations between characteristics of Premature Atrial Contraction (PAC) 6 months after catheter ablation (CA) and later recurrence are not known. We investigated the effects of PAC characteristics on long-term outcomes of initially successful Atrial fibrillation (AF) ablation.Methods and Results:In all, 378 patients (mean age 61 years, 21% female, 67% paroxysmal AF) who underwent initial radiofrequency CA for AF without recurrence up to 24-h Holter monitoring 6 months after the procedure were reviewed retrospectively. The calculated number of PAC/24 h and the length of the longest PAC run during Holter recording were analyzed. After 4.3±1.2 years (mean±SD) follow-up, 123 (32.5%) patients experienced late recurrence. Patients with recurrence had significantly more PAC/24 h (median [interquartile range] 110 [33-228] vs. 42 [16-210]; P<0.01) and a longer longest PAC run (5 [2-8] vs. 3 [1-5]; P<0.01) than those without. Receiver operating characteristic curve analysis indicated 58 PAC/24 h and a longest PAC run of 5 were optimal cut-off values for predicting recurrence. After adjusting for previously reported predictors of late recurrence, frequent PAC (≥58/24 h) and longest PAC run ≥5 were found to be independent predictors of late recurrence (hazard ratios [95% confidence intervals] 1.93 [1.24-3.02; P<0.01] and 1.81 [1.20-2.76; P<0.01], respectively). CONCLUSIONS Six months after successful AF ablation, both frequent PAC and long PAC run are independent predictors of late recurrence.

  • Burden and Long Firing of Premature Atrial Contraction Early After Catheter Ablation Predict Late Recurrence of Atrial Fibrillation
    Circulation journal : official journal of the Japanese Circulation Society, 2020
    Co-Authors: Hiroyuki Inoue, Nobuaki Tanaka, Koji Tanaka, Yuichi Ninomiya, Yuko Hirao, Takafumi Oka, Masato Okada, Ryo Kitagaki, Kohtaro Takayasu, Yasushi Koyama
    Abstract:

    BACKGROUND Associations between characteristics of Premature Atrial Contraction (PAC) 6 months after catheter ablation (CA) and later recurrence are not known. We investigated the effects of PAC characteristics on long-term outcomes of initially successful Atrial fibrillation (AF) ablation.Methods and Results:In all, 378 patients (mean age 61 years, 21% female, 67% paroxysmal AF) who underwent initial radiofrequency CA for AF without recurrence up to 24-h Holter monitoring 6 months after the procedure were reviewed retrospectively. The calculated number of PAC/24 h and the length of the longest PAC run during Holter recording were analyzed. After 4.3±1.2 years (mean±SD) follow-up, 123 (32.5%) patients experienced late recurrence. Patients with recurrence had significantly more PAC/24 h (median [interquartile range] 110 [33-228] vs. 42 [16-210]; P