The Experts below are selected from a list of 1548 Experts worldwide ranked by ideXlab platform
Lino Goncalves - One of the best experts on this subject based on the ideXlab platform.
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Pattern Matching Filter and multielectrode mapping catheter – A new approach for complex Premature Ventricular Contraction ablation
'Elsevier BV', 2021Co-Authors: Pedro A. Sousa, Natalia Antonio, Sergio Barra, Luis Elvas, Lino GoncalvesAbstract:Purpose: Our goal was to assess usefulness of Pattern Matching Filter (PMF) software combined with the PentaRay catheter for complex Premature Ventricular Contraction (PVC) ablation. Methods: A prospective observational study of consecutive patients referred for complex PVC ablation at our tertiary center from January to September 2018. Patients underwent ablation using a pre-specified mapping strategy with the PMF and the PentaRay catheter (PVCs with ≥97% correlation with the template morphology were collected). Procedural endpoints and acute and 12-months success rates were assessed and compared to a retrospective cohort of patients who also underwent a complex PVC ablation with standard activation mapping performed with a Thermocool SmartTouch catheter. Results: During the nine-month enrollment period, seven patients fulfilled our inclusion criteria, while there were four patients in the control group. Patients treated with the PMF and PentaRay had a fivefold number of points acquired (507±213 vs. 90±62) and a halved procedure time (67±42 vs.130±54 min), required a shorter radiofrequency ablation time (294±112 vs.706±613 sec) and had a higher overall success rate (100% vs.75%) when compared to the standard approach. No major complications occurred in either group. Conclusions: In this first study assessing the combined use of the PentaRay catheter and the PMF for complex PVCs ablation, we demonstrate how this approach can improve the level of detail, accuracy and reliability of the activation map, while reducing the number of radiofrequency applications and procedural time. Further studies are warranted to confirm whether this approach can lead to improved outcomes. Resumo: Objetivo: Avaliar a utilidade da abordagem conjunta do software Pattern Matching Filter (PMF) com o cateter PentaRay na ablação de extrassístole Ventricular (ESV) complexa. Métodos: Estudo observacional prospetivo de doentes consecutivos referenciados para ablação de ESV complexa (re-dos ou ESV esquerda) de janeiro a setembro de 2018. Os pacientes foram submetidos a uma estratégia de mapeamento predefinida com o PMF e o cateter PentaRay (ESV com ≥97% de correlação com a morfologia definida). Os objetivos primários, bem como o sucesso agudo e a 12 meses, foram avaliados e comparados com uma coorte retrospetiva de pacientes também sujeitos a ablação de ESV complexa mas com um mapa de ativação convencional realizado com o cateter de ablação Thermocool SmartTouch. Resultados: Durante os nove meses foram incluídos sete pacientes que preencheram os critérios e quatro foram no grupo controlo. Os pacientes tratados com o PMF e o cateter PentaRay tiveram cinco vezes mais pontos adquiridos (507±213 versus 90±62) e metade do tempo de procedimento (67±42 versus 130±54 min), apresentaram menor tempo de ablação (294±112 versus 706±613 sec) e uma maior taxa de sucesso (100% versus 75%) quando comparados com a abordagem convencional. Não se verificaram complicações em ambos os grupos. Conclusões: Neste primeiro estudo a avaliar a abordagem conjunta do cateter PentaRay com o PMF para a ablação de ESV complexa, demonstramos que esta abordagem melhora o detalhe, a precisão e a fiabilidade do mapa de ativação, ao mesmo tempo que reduz o tempo de radiofrequência e do procedimento. Estudos adicionais serão necessários para confirmar se esta abordagem melhora o sucesso
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pattern matching filter and multielectrode mapping catheter a new approach for complex Premature Ventricular Contraction ablation
Revista Portuguesa De Pneumologia, 2020Co-Authors: Pedro Sousa, Natalia Antonio, Sergio Barra, Luis Elvas, Lino GoncalvesAbstract:Abstract Purpose Our goal was to assess usefulness of Pattern Matching Filter (PMF) software combined with the PentaRay catheter for complex Premature Ventricular Contraction (PVC) ablation. Methods A prospective observational study of consecutive patients referred for complex PVC ablation at our tertiary center from January to September 2018. Patients underwent ablation using a pre-specified mapping strategy with the PMF and the PentaRay catheter (PVCs with ≥97% correlation with the template morphology were collected). Procedural endpoints and acute and 12-months success rates were assessed and compared to a retrospective cohort of patients who also underwent a complex PVC ablation with standard activation mapping performed with a Thermocool SmartTouch catheter. Results During the nine-month enrollment period, seven patients fulfilled our inclusion criteria, while there were four patients in the control group. Patients treated with the PMF and PentaRay had a fivefold number of points acquired (507±213 vs. 90±62) and a halved procedure time (67±42 vs.130±54 min), required a shorter radiofrequency ablation time (294±112 vs.706±613 sec) and had a higher overall success rate (100% vs.75%) when compared to the standard approach. No major complications occurred in either group. Conclusions In this first study assessing the combined use of the PentaRay catheter and the PMF for complex PVCs ablation, we demonstrate how this approach can improve the level of detail, accuracy and reliability of the activation map, while reducing the number of radiofrequency applications and procedural time. Further studies are warranted to confirm whether this approach can lead to improved outcomes.
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multielectrode mapping and pattern matching recognition for left Premature Ventricular Contraction ablation
JACC: Clinical Electrophysiology, 2019Co-Authors: Pedro Sousa, Natalia Antonio, Sergio Barra, Luis Elvas, Lino GoncalvesAbstract:Catheter ablation is an established treatment for Premature Ventricular Contraction (PVC). Nevertheless, when the PVC arises from the left Ventricular outflow tract, success rates are invariably lower [(1,2)][1]. We present a new approach for left PVC ablation using a new module entitled “Pattern
Marmar Vaseghi - One of the best experts on this subject based on the ideXlab platform.
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Premature Ventricular Contractions activate vagal afferents and alter autonomic tone implications for Premature Ventricular Contraction induced cardiomyopathy
American Journal of Physiology-heart and Circulatory Physiology, 2019Co-Authors: Siamak Salavatian, Andrew J Armour, Naoko Yamaguchi, Jonathan D Hoang, Saloni Patel, Jeffrey L Ardell, Marmar VaseghiAbstract:Premature Ventricular Contractions (PVCs) are common in many patients and, at an increased burden, are known to cause heart failure. This study determined that PVCs powerfully modulate cardiac vaga...
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Premature Ventricular Contraction coupling interval variability destabilizes cardiac neuronal and electrophysiological control insights from simultaneous cardioneural mapping
Circulation-arrhythmia and Electrophysiology, 2017Co-Authors: David Hamon, Pradeep S Rajendran, Ray W Chui, Olujimi A Ajijola, Tadanobu Irie, Ramin Talebi, Siamak Salavatian, Marmar Vaseghi, Jason S Bradfield, Andrew J ArmourAbstract:Background— Variability in Premature Ventricular Contraction (PVC) coupling interval (CI) increases the risk of cardiomyopathy and sudden death. The autonomic nervous system regulates cardiac electrical and mechanical indices, and its dysregulation plays an important role in cardiac disease pathogenesis. The impact of PVCs on the intrinsic cardiac nervous system, a neural network on the heart, remains unknown. The objective was to determine the effect of PVCs and CI on intrinsic cardiac nervous system function in generating cardiac neuronal and electric instability using a novel cardioneural mapping approach. Methods and Results— In a porcine model (n=8), neuronal activity was recorded from a Ventricular ganglion using a microelectrode array, and cardiac electrophysiological mapping was performed. Neurons were functionally classified based on their response to afferent and efferent cardiovascular stimuli, with neurons that responded to both defined as convergent (local reflex processors). Dynamic changes in neuronal activity were then evaluated in response to right Ventricular outflow tract PVCs with fixed short, fixed long, and variable CI. PVC delivery elicited a greater neuronal response than all other stimuli ( P <0.001). Compared with fixed short and long CI, PVCs with variable CI had a greater impact on neuronal response ( P <0.05 versus short CI), particularly on convergent neurons ( P <0.05), as well as neurons receiving sympathetic ( P <0.05) and parasympathetic input ( P <0.05). The greatest cardiac electric instability was also observed after variable (short) CI PVCs. Conclusions— Variable CI PVCs affect critical populations of intrinsic cardiac nervous system neurons and alter cardiac repolarization. These changes may be critical for arrhythmogenesis and remodeling, leading to cardiomyopathy.
Joon S. Lim - One of the best experts on this subject based on the ideXlab platform.
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Finding features for real-time Premature Ventricular Contraction detection using a fuzzy neural network system
IEEE Transactions on Neural Networks, 2009Co-Authors: Joon S. LimAbstract:Fuzzy neural networks (FNNs) have been successfully applied to generate predictive rules for medical or diagnostic data. This brief presents an approach to detect Premature Ventricular Contractions (PVCs) using the neural network with weighted fuzzy membership functions (NEWFMs). The NEWFM classifies normal and PVC beats by the trained bounded sum of weighted fuzzy membership functions (BSWFMs) using wavelet transformed coefficients from the MIT-BIH PVC database. The eight generalized coefficients, locally related to the time signal, are extracted by the nonoverlap area distribution measurement method. The eight generalized coefficients are used for the three PVC data sets with reliable accuracy rates of 99.80%, 99.21%, and 98.78%, respectively, which means that the selected features are less dependent on the data sets. It is shown that the locations of the eight features are not only around the QRS complex that represents Ventricular depolarization in the electrocardiogram (ECG) containing a Q wave, an R wave, and an S wave, but also the QR segment from the Q wave to the R wave has more discriminate information than the RS segment from the R wave to the S wave. The BSWFMs of the eight features trained by NEWFM are shown visually, which makes the features explicitly interpretable. Since each BSWFM combines multiple weighted fuzzy membership functions into one using the bounded sum, the eight small-sized BSWFMs can realize real-time PVC detection in a mobile environment.
Pedro Sousa - One of the best experts on this subject based on the ideXlab platform.
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pattern matching filter and multielectrode mapping catheter a new approach for complex Premature Ventricular Contraction ablation
Revista Portuguesa De Pneumologia, 2020Co-Authors: Pedro Sousa, Natalia Antonio, Sergio Barra, Luis Elvas, Lino GoncalvesAbstract:Abstract Purpose Our goal was to assess usefulness of Pattern Matching Filter (PMF) software combined with the PentaRay catheter for complex Premature Ventricular Contraction (PVC) ablation. Methods A prospective observational study of consecutive patients referred for complex PVC ablation at our tertiary center from January to September 2018. Patients underwent ablation using a pre-specified mapping strategy with the PMF and the PentaRay catheter (PVCs with ≥97% correlation with the template morphology were collected). Procedural endpoints and acute and 12-months success rates were assessed and compared to a retrospective cohort of patients who also underwent a complex PVC ablation with standard activation mapping performed with a Thermocool SmartTouch catheter. Results During the nine-month enrollment period, seven patients fulfilled our inclusion criteria, while there were four patients in the control group. Patients treated with the PMF and PentaRay had a fivefold number of points acquired (507±213 vs. 90±62) and a halved procedure time (67±42 vs.130±54 min), required a shorter radiofrequency ablation time (294±112 vs.706±613 sec) and had a higher overall success rate (100% vs.75%) when compared to the standard approach. No major complications occurred in either group. Conclusions In this first study assessing the combined use of the PentaRay catheter and the PMF for complex PVCs ablation, we demonstrate how this approach can improve the level of detail, accuracy and reliability of the activation map, while reducing the number of radiofrequency applications and procedural time. Further studies are warranted to confirm whether this approach can lead to improved outcomes.
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multielectrode mapping and pattern matching recognition for left Premature Ventricular Contraction ablation
JACC: Clinical Electrophysiology, 2019Co-Authors: Pedro Sousa, Natalia Antonio, Sergio Barra, Luis Elvas, Lino GoncalvesAbstract:Catheter ablation is an established treatment for Premature Ventricular Contraction (PVC). Nevertheless, when the PVC arises from the left Ventricular outflow tract, success rates are invariably lower [(1,2)][1]. We present a new approach for left PVC ablation using a new module entitled “Pattern
Andrew J Armour - One of the best experts on this subject based on the ideXlab platform.
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Premature Ventricular Contractions activate vagal afferents and alter autonomic tone implications for Premature Ventricular Contraction induced cardiomyopathy
American Journal of Physiology-heart and Circulatory Physiology, 2019Co-Authors: Siamak Salavatian, Andrew J Armour, Naoko Yamaguchi, Jonathan D Hoang, Saloni Patel, Jeffrey L Ardell, Marmar VaseghiAbstract:Premature Ventricular Contractions (PVCs) are common in many patients and, at an increased burden, are known to cause heart failure. This study determined that PVCs powerfully modulate cardiac vaga...
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Premature Ventricular Contraction coupling interval variability destabilizes cardiac neuronal and electrophysiological control insights from simultaneous cardioneural mapping
Circulation-arrhythmia and Electrophysiology, 2017Co-Authors: David Hamon, Pradeep S Rajendran, Ray W Chui, Olujimi A Ajijola, Tadanobu Irie, Ramin Talebi, Siamak Salavatian, Marmar Vaseghi, Jason S Bradfield, Andrew J ArmourAbstract:Background— Variability in Premature Ventricular Contraction (PVC) coupling interval (CI) increases the risk of cardiomyopathy and sudden death. The autonomic nervous system regulates cardiac electrical and mechanical indices, and its dysregulation plays an important role in cardiac disease pathogenesis. The impact of PVCs on the intrinsic cardiac nervous system, a neural network on the heart, remains unknown. The objective was to determine the effect of PVCs and CI on intrinsic cardiac nervous system function in generating cardiac neuronal and electric instability using a novel cardioneural mapping approach. Methods and Results— In a porcine model (n=8), neuronal activity was recorded from a Ventricular ganglion using a microelectrode array, and cardiac electrophysiological mapping was performed. Neurons were functionally classified based on their response to afferent and efferent cardiovascular stimuli, with neurons that responded to both defined as convergent (local reflex processors). Dynamic changes in neuronal activity were then evaluated in response to right Ventricular outflow tract PVCs with fixed short, fixed long, and variable CI. PVC delivery elicited a greater neuronal response than all other stimuli ( P <0.001). Compared with fixed short and long CI, PVCs with variable CI had a greater impact on neuronal response ( P <0.05 versus short CI), particularly on convergent neurons ( P <0.05), as well as neurons receiving sympathetic ( P <0.05) and parasympathetic input ( P <0.05). The greatest cardiac electric instability was also observed after variable (short) CI PVCs. Conclusions— Variable CI PVCs affect critical populations of intrinsic cardiac nervous system neurons and alter cardiac repolarization. These changes may be critical for arrhythmogenesis and remodeling, leading to cardiomyopathy.
