The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform
Shannon S Stahl - One of the best experts on this subject based on the ideXlab platform.
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electrochemical aminoxyl mediated oxidation of Primary Alcohols in lignin to carboxylic acids polymer modification and depolymerization
Journal of the American Chemical Society, 2019Co-Authors: Mohammad Rafiee, Manar Alherech, Steven D Karlen, Shannon S StahlAbstract:An electrochemical process has been developed for chemoselective oxidation of Primary Alcohols in lignin to the corresponding carboxylic acids. The electrochemical oxidation reactions proceed under...
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copper i tempo catalyzed aerobic oxidation of Primary Alcohols to aldehydes with ambient air
Nature Protocols, 2012Co-Authors: Jessica M Hoover, Janelle E Steves, Shannon S StahlAbstract:Copper(I)/TEMPO-catalyzed aerobic oxidation of Primary Alcohols to aldehydes with ambient air
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highly practical copper i tempo catalyst system for chemoselective aerobic oxidation of Primary Alcohols
ChemInform, 2012Co-Authors: Jessica M Hoover, Shannon S StahlAbstract:The aerobic catalytic system is developed that exhibits high selectivity for Primary Alcohols and mediates efficient oxidation of aliphatic substrates.
Huiying Zeng - One of the best experts on this subject based on the ideXlab platform.
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Dearomatization-Rearomatization Strategy for ortho-Selective Alkylation of Phenols with Primary Alcohols.
Angewandte Chemie (International ed. in English), 2020Co-Authors: Huiying ZengAbstract:Phenols are common precursors and core structures of a variety of industrial chemicals, ranging from pharmaceuticals to polymers. However, the synthesis of site-specifically substituted phenols is challenging, and thus the development of new methods for this purpose would be highly desirable. Herein, we report a protocol for palladium-catalyzed ortho -selective alkylation reactions of phenols with Primary Alcohols via a dearomatization-rearomatization strategy, with water as the sole by-product. Various substituted phenols and Primary Alcohols were compatible with the standard reaction conditions. The detailed mechanism of this transformation was also investigated.
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palladium catalyzed aerobic synthesis of ortho substituted phenols from cyclohexanones and Primary Alcohols
Chemical Communications, 2020Co-Authors: Huiying ZengAbstract:Due to the importance of phenols as structural cores and precursors of chemical products, synthesis of site-specific substituted phenols is highly desirable and a significant challenge. An aerobic palladium-catalyzed site-specific synthesis of ortho-substituted phenols from cyclohexanones and Primary Alcohols via an oxidation/aldol/dehydration/aromatization process has been developed. Various substituted cyclohexanones and Primary Alcohols are successfully transformed into ortho-substituted phenols. In addition, this catalytic reaction uses air as the terminal oxidant and generates water as the sole by-product. Furthermore, the method can also be extended to polyhydroxyl substituted substrates with high chemoselectivity between Primary and secondary Alcohols. This method provides a greener tool for synthesizing Primary alkyl ortho-substituted phenols.
Chan Sik Cho - One of the best experts on this subject based on the ideXlab platform.
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A palladium-catalyzed route for α-alkylation of ketones by Primary Alcohols
Journal of Molecular Catalysis A: Chemical, 2005Co-Authors: Chan Sik ChoAbstract:Abstract Ketones react with Primary Alcohols in dioxane at 100 °C in the presence of a catalytic amount of Pd/C and KOH along with 1-decene as a sacrificial hydrogen acceptor to give the corresponding coupled ketones in moderate to good yields. The catalytic pathway seems to be proceeded via a sequence involving initial oxidation of Primary Alcohols to aldehydes, cross aldol condensation, and regioselective reduction.
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Ruthenium-catalyzed regioselective α-alkylation of ketones with Primary Alcohols
Tetrahedron Letters, 2002Co-Authors: Chan Sik Cho, Tae-jeong Kim, Bok Tae Kim, Sang Chul ShimAbstract:Ketones are regioselectively alkylated with an array of Primary Alcohols in dioxane at 80°C in the presence of a catalytic amount of a ruthenium catalyst together with KOH and a hydrogen acceptor.
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Ruthenium-catalyzed regioselective -alkylation of ketones with Primary Alcohols
2002Co-Authors: Chan Sik Cho, Tae-jeong Kim, Bok Tae Kim, Sang Chul ShimAbstract:Ketones are regioselectively alkylated with an array of Primary Alcohols in dioxane at 80°C in the presence of a catalytic amount of a ruthenium catalyst together with KOH and a hydrogen acceptor. © 2002 Elsevier Science Ltd. All rights reserved. -Alkylation of ketones has been known as a fundamental tool for a carbon carbon -bond formation in synthetic organic chemistry. The alkylation is generally achieved by the coupling between nucleophilic enolates (enolate equivalents) and electrophilic alkylating agents and regioselectivity is determined by initial enolate formation. In connection with this report, during the course of our ongoing studies on ruthenium catalysis, we recently found an unusual type of rutheniumcatalyzed transfer hydrogenation of ketones by Primary Alcohols. The reaction gives mainly an unconventional transfer hydrogenated secondary alcohol accompanied by C–C coupling with concomitant formation of an alkylated ketone (Scheme 1). The preferential formaScheme 1. Table 1. Ruthenium-catalyzed -alkylation of 1 with 2 under several conditions Time (h) Hydrogen acceptor Yield (%) Temp. (°C) Entry
Jessica M Hoover - One of the best experts on this subject based on the ideXlab platform.
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copper i tempo catalyzed aerobic oxidation of Primary Alcohols to aldehydes with ambient air
Nature Protocols, 2012Co-Authors: Jessica M Hoover, Janelle E Steves, Shannon S StahlAbstract:Copper(I)/TEMPO-catalyzed aerobic oxidation of Primary Alcohols to aldehydes with ambient air
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highly practical copper i tempo catalyst system for chemoselective aerobic oxidation of Primary Alcohols
ChemInform, 2012Co-Authors: Jessica M Hoover, Shannon S StahlAbstract:The aerobic catalytic system is developed that exhibits high selectivity for Primary Alcohols and mediates efficient oxidation of aliphatic substrates.
Aiwen Lei - One of the best experts on this subject based on the ideXlab platform.
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transition metal free aerobic oxidation of Primary Alcohols to carboxylic acids
New Journal of Chemistry, 2013Co-Authors: Jing Wang, Chao Liu, Aiwen Lei, Jiwen YuanAbstract:A transition-metal-free aerobic oxidation of Primary Alcohols to acids was achieved in the presence of a base. This transformation provides an effective protocol towards the synthesis of aryl, alkyl, heterocyclic and vinyl carboxylic acids.
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oxidant controlled pd catalysed selective oxidation of Primary Alcohols
Chemical Communications, 2013Co-Authors: Chao Liu, Shan Tang, Aiwen LeiAbstract:The oxidant controlled palladium catalysed selective oxidation of Primary Alcohols to aldehydes or esters was investigated. The electronic properties of the benzylic Alcohols and the structure of the oxidant are both important factors in controlling the selectivity between aldehydes and esters. A covalent benzyl ligand derived from BnCl provides η3 coordination to the Pd centre. This covalent ligand is the key to the selective oxidative esterification of Primary Alcohols.
