The Experts below are selected from a list of 5661 Experts worldwide ranked by ideXlab platform
Joseph S. Sanfilippo - One of the best experts on this subject based on the ideXlab platform.
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Primary Amenorrhea with transverse vaginal septum and scant hematocolpos: A case report
Open Journal of Pediatrics, 2012Co-Authors: Lori Homa, Semara Thomas, Joseph S. SanfilippoAbstract:Background: A genital outflow tract obstruction is an uncommon cause of Primary Amenorrhea. If ovulation occurs, menstrual bleeding is prevented. Patients typically present with abdominal/pelvic pain due to hematocolpos. Absence of significant hematocolpos could indicate a secondary source of Primary Amenorrhea and be challenging to the clinical diagnosis. Case: 17 year-old patient with Primary Amenorrhea, appropriate Tanner staging secondary sex characteristics, and transverse vaginal septum presents with virtual absence of hematocolpos. After vaginal septum resection, the patient began menstruating, although only evidenced by two cycles of vaginal spotting. Conclusion: Significant hematocolpos is an expected sequella of distal outlet obstruction when collated with secondary sexual characteristics. Absence of such along with suboptimal return of menstruation reflects pathophysiology which may be attributed to a coexistent disorder of the hypothalamus or higher central nervous system function.
C M Peterson - One of the best experts on this subject based on the ideXlab platform.
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Multiple endocrine neoplasia presenting as Primary Amenorrhea: a case report.
Obstetrics and gynecology, 1995Co-Authors: K Lythgoe, R Dotson, C M PetersonAbstract:Primary Amenorrhea is rarely secondary to hyperprolactinemia. This case highlights the importance of obtaining a complete family history to identify patients who may have hyperprolactinemia secondary to multiple endocrine neoplasia type 1 syndrome. A 16-year-old female presented with Primary Amenorrhea and was noted to have hyperprolactinemia. Her family history revealed an extensive family tree consistent with multiple endocrine neoplasia type 1 syndrome. She was diagnosed subsequently with the syndrome, having both pituitary and parathyroid adenomas. A detailed family history of patients with hyperprolactinemia secondary to a pituitary adenoma may prompt a serum calcium measurement, which may identify patients at risk for development of multiple endocrine neoplasia type 1 syndrome.
Lythgoe K - One of the best experts on this subject based on the ideXlab platform.
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Multiple endocrine neoplasia presenting as Primary Amenorrhea: A case report
Obstetrics & Gynecology, 1995Co-Authors: Lythgoe KAbstract:Background Primary Amenorrhea is rarely secondary to hyperprolactinemia. This case highlights the importance of obtaining a complete family history to identify patients who may have hyperprolactinemia secondary to multiple endocrine neoplasia type 1 syndrome. Case A 16-year-old female presented with Primary Amenorrhea and was noted to have hyperprolactinemia. Her family history revealed an extensive family tree consistent with multiple endocrine neoplasia type 1 syndrome. She was diagnosed subsequently with the syndrome, having both pituitary and parathyroid adenomas. Conclusion A detailed family history of patients with hyperprolactinemia secondary to a pituitary adenoma may prompt a serum calcium measurement, which may identify patients at risk for development of multiple endocrine neoplasia type 1 syndrome.
Laurent Garel - One of the best experts on this subject based on the ideXlab platform.
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Female Pelvis: Precocious Puberty—Primary Amenorrhea
Imaging Endocrine Diseases in Children, 2012Co-Authors: Laurent GarelAbstract:Puberty is induced by the activation of the hypothalamic gonadotropin-releasing hormone pulse generator. Puberty is defined by the age of menarche, pubertal onset by the development of breast buds. Menarche usually occurs 2–5 years after budding. Pelvic ultrasound is both simple and effective in pediatrics to assess the pubertal status and to contribute to the etiological workup of prepubertal bleeding and Primary Amenorrhea. Apart from isolated premature thelarche and isolated premature pubarche where pelvic ultrasound displays normal prepubertal features, pubertal precocities encompass the central precocious puberties (gonadotropin-dependent) and the peripheral precocious puberties (gonadotropin-independent) which are distinctive both on imaging and biology. Conversely pubertal delay and Primary Amenorrhea may be linked to numerous causes: uterine and ovarian sonographic characteristics allow for the rapid recognition of Turner syndrome, mullerian duct anomalies, abnormal sex differentiation, or ovarian tumors. Magnetic Resonance Imaging (MRI) is clearly indicated in Mullerian duct aplasia, in central precocious puberty and in the workup of hypothalamo–pituitary-related Primary Amenorrhea.
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female pelvis precocious puberty Primary Amenorrhea
2012Co-Authors: Laurent GarelAbstract:Puberty is induced by the activation of the hypothalamic gonadotropin-releasing hormone pulse generator. Puberty is defined by the age of menarche, pubertal onset by the development of breast buds. Menarche usually occurs 2–5 years after budding. Pelvic ultrasound is both simple and effective in pediatrics to assess the pubertal status and to contribute to the etiological workup of prepubertal bleeding and Primary Amenorrhea. Apart from isolated premature thelarche and isolated premature pubarche where pelvic ultrasound displays normal prepubertal features, pubertal precocities encompass the central precocious puberties (gonadotropin-dependent) and the peripheral precocious puberties (gonadotropin-independent) which are distinctive both on imaging and biology. Conversely pubertal delay and Primary Amenorrhea may be linked to numerous causes: uterine and ovarian sonographic characteristics allow for the rapid recognition of Turner syndrome, mullerian duct anomalies, abnormal sex differentiation, or ovarian tumors. Magnetic Resonance Imaging (MRI) is clearly indicated in Mullerian duct aplasia, in central precocious puberty and in the workup of hypothalamo–pituitary-related Primary Amenorrhea.
Lori Homa - One of the best experts on this subject based on the ideXlab platform.
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Primary Amenorrhea with transverse vaginal septum and scant hematocolpos: A case report
Open Journal of Pediatrics, 2012Co-Authors: Lori Homa, Semara Thomas, Joseph S. SanfilippoAbstract:Background: A genital outflow tract obstruction is an uncommon cause of Primary Amenorrhea. If ovulation occurs, menstrual bleeding is prevented. Patients typically present with abdominal/pelvic pain due to hematocolpos. Absence of significant hematocolpos could indicate a secondary source of Primary Amenorrhea and be challenging to the clinical diagnosis. Case: 17 year-old patient with Primary Amenorrhea, appropriate Tanner staging secondary sex characteristics, and transverse vaginal septum presents with virtual absence of hematocolpos. After vaginal septum resection, the patient began menstruating, although only evidenced by two cycles of vaginal spotting. Conclusion: Significant hematocolpos is an expected sequella of distal outlet obstruction when collated with secondary sexual characteristics. Absence of such along with suboptimal return of menstruation reflects pathophysiology which may be attributed to a coexistent disorder of the hypothalamus or higher central nervous system function.