The Experts below are selected from a list of 129 Experts worldwide ranked by ideXlab platform
Bo Tang - One of the best experts on this subject based on the ideXlab platform.
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Determination of Procaine hydrochloride by fluorimetry
Guang pu xue yu guang pu fen xi = Guang pu, 2002Co-Authors: Yue Sun, Huai You Wang, Bo TangAbstract:Use of fluorescence spectrophotometry for the determination of Procaine hydrochloride in injection solution of Procaine hydrochloride in suggested based on fluorescence property of 4-aminobenzoate which is a hydrolysis product of the Procaine hydrochloride in pH 12, with exciatation wavelength and emission wavelength at 268 and 340 nm, respectively. Under this condition, a linear relationship is obtained between Procaine hydrochloride and the relative fluorescence intensity. The linear regression equation of the calibration graph is c = 0.022I-0.081, with a linear regression correlative coefficient of 0.9996 and relative standard deviation (RSD) of 3.4%. Influences of pH, foreign ions, kanamycin, gentamycin, benylpencillin, streptomycin and standing for time on the determination of Procaine hydrochloride have been examined. The reasons that the relative fluorescence intensity of Procaine hydrochloride increases with a rise in pH and with standing for time are discussed. The detection limit of this method is 49 ng.mL-1. The results obtained by the method agreed with those by the official method. The method is simple, and available to be used in the determination of Procaine hydrochloride in injection solution.
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use of p dimethylaminobenzalhyde as a colored reagent for determination of Procaine hydrochloride by spectrophotometry
Talanta, 2000Co-Authors: Lian Dong Liu, Yue Sun, Huai You Wang, Yuan Liu, Bo TangAbstract:Spectrophotometric determination of Procaine hydrochloride is described. The Procaine hydrochloride reacts with p-dimethylaminobenzalhyde in glacial acetic acid to form an Schiff base which is a yellow compound, and its maximum absorption wavelength is at 455nm, epsilon(455)=3.46x10(4). The absorbance for Procaine hydrochloride from 0.2 to 15 mug ml(-1) obeys Beer's law. The linear regression equation of the calibration graph is C=5.866A-0.02, with a linear regression correlative coefficient is 0.9994 and relative standard deviation (RSD) of 1.7%; the detection limit is 0.1 mug ml(-1); recovery is from 92.0 to 110.0%. Effects of reaction medium, temperature, gentamycin, beneylpenicillin, kanamycin, streptomycin, foreign ions, and stand for time on the determination of Procaine hydrochloride have been examined. The results obtained by this method agreed with those by the official method (dead-stop titration). This method is rapid and simple, and can be used for the determination of Procaine hydrochloride in injection solution of Procaine hydrochloride.
Thomas J Bigger - One of the best experts on this subject based on the ideXlab platform.
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intermittent intravenous Procaine amide to treat ventricular arrhythmias
Annals of Internal Medicine, 2020Co-Authors: Elsagrace V Giardina, Robert H Heissenbuttel, Thomas J BiggerAbstract:Abstract Twenty patients with ventricular arrhythmias were treated with Procaine amide to determine an antiarrhythmic plasma drug concentration range and to observe Procaine amide's effect on blood...
Elsagrace V Giardina - One of the best experts on this subject based on the ideXlab platform.
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intermittent intravenous Procaine amide to treat ventricular arrhythmias
Annals of Internal Medicine, 2020Co-Authors: Elsagrace V Giardina, Robert H Heissenbuttel, Thomas J BiggerAbstract:Abstract Twenty patients with ventricular arrhythmias were treated with Procaine amide to determine an antiarrhythmic plasma drug concentration range and to observe Procaine amide's effect on blood...
Yue Sun - One of the best experts on this subject based on the ideXlab platform.
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Determination of Procaine hydrochloride by fluorimetry
Guang pu xue yu guang pu fen xi = Guang pu, 2002Co-Authors: Yue Sun, Huai You Wang, Bo TangAbstract:Use of fluorescence spectrophotometry for the determination of Procaine hydrochloride in injection solution of Procaine hydrochloride in suggested based on fluorescence property of 4-aminobenzoate which is a hydrolysis product of the Procaine hydrochloride in pH 12, with exciatation wavelength and emission wavelength at 268 and 340 nm, respectively. Under this condition, a linear relationship is obtained between Procaine hydrochloride and the relative fluorescence intensity. The linear regression equation of the calibration graph is c = 0.022I-0.081, with a linear regression correlative coefficient of 0.9996 and relative standard deviation (RSD) of 3.4%. Influences of pH, foreign ions, kanamycin, gentamycin, benylpencillin, streptomycin and standing for time on the determination of Procaine hydrochloride have been examined. The reasons that the relative fluorescence intensity of Procaine hydrochloride increases with a rise in pH and with standing for time are discussed. The detection limit of this method is 49 ng.mL-1. The results obtained by the method agreed with those by the official method. The method is simple, and available to be used in the determination of Procaine hydrochloride in injection solution.
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use of p dimethylaminobenzalhyde as a colored reagent for determination of Procaine hydrochloride by spectrophotometry
Talanta, 2000Co-Authors: Lian Dong Liu, Yue Sun, Huai You Wang, Yuan Liu, Bo TangAbstract:Spectrophotometric determination of Procaine hydrochloride is described. The Procaine hydrochloride reacts with p-dimethylaminobenzalhyde in glacial acetic acid to form an Schiff base which is a yellow compound, and its maximum absorption wavelength is at 455nm, epsilon(455)=3.46x10(4). The absorbance for Procaine hydrochloride from 0.2 to 15 mug ml(-1) obeys Beer's law. The linear regression equation of the calibration graph is C=5.866A-0.02, with a linear regression correlative coefficient is 0.9994 and relative standard deviation (RSD) of 1.7%; the detection limit is 0.1 mug ml(-1); recovery is from 92.0 to 110.0%. Effects of reaction medium, temperature, gentamycin, beneylpenicillin, kanamycin, streptomycin, foreign ions, and stand for time on the determination of Procaine hydrochloride have been examined. The results obtained by this method agreed with those by the official method (dead-stop titration). This method is rapid and simple, and can be used for the determination of Procaine hydrochloride in injection solution of Procaine hydrochloride.
Huai You Wang - One of the best experts on this subject based on the ideXlab platform.
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Determination of Procaine hydrochloride by fluorimetry
Guang pu xue yu guang pu fen xi = Guang pu, 2002Co-Authors: Yue Sun, Huai You Wang, Bo TangAbstract:Use of fluorescence spectrophotometry for the determination of Procaine hydrochloride in injection solution of Procaine hydrochloride in suggested based on fluorescence property of 4-aminobenzoate which is a hydrolysis product of the Procaine hydrochloride in pH 12, with exciatation wavelength and emission wavelength at 268 and 340 nm, respectively. Under this condition, a linear relationship is obtained between Procaine hydrochloride and the relative fluorescence intensity. The linear regression equation of the calibration graph is c = 0.022I-0.081, with a linear regression correlative coefficient of 0.9996 and relative standard deviation (RSD) of 3.4%. Influences of pH, foreign ions, kanamycin, gentamycin, benylpencillin, streptomycin and standing for time on the determination of Procaine hydrochloride have been examined. The reasons that the relative fluorescence intensity of Procaine hydrochloride increases with a rise in pH and with standing for time are discussed. The detection limit of this method is 49 ng.mL-1. The results obtained by the method agreed with those by the official method. The method is simple, and available to be used in the determination of Procaine hydrochloride in injection solution.
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use of p dimethylaminobenzalhyde as a colored reagent for determination of Procaine hydrochloride by spectrophotometry
Talanta, 2000Co-Authors: Lian Dong Liu, Yue Sun, Huai You Wang, Yuan Liu, Bo TangAbstract:Spectrophotometric determination of Procaine hydrochloride is described. The Procaine hydrochloride reacts with p-dimethylaminobenzalhyde in glacial acetic acid to form an Schiff base which is a yellow compound, and its maximum absorption wavelength is at 455nm, epsilon(455)=3.46x10(4). The absorbance for Procaine hydrochloride from 0.2 to 15 mug ml(-1) obeys Beer's law. The linear regression equation of the calibration graph is C=5.866A-0.02, with a linear regression correlative coefficient is 0.9994 and relative standard deviation (RSD) of 1.7%; the detection limit is 0.1 mug ml(-1); recovery is from 92.0 to 110.0%. Effects of reaction medium, temperature, gentamycin, beneylpenicillin, kanamycin, streptomycin, foreign ions, and stand for time on the determination of Procaine hydrochloride have been examined. The results obtained by this method agreed with those by the official method (dead-stop titration). This method is rapid and simple, and can be used for the determination of Procaine hydrochloride in injection solution of Procaine hydrochloride.