Process Development

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The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform

John M Woodley - One of the best experts on this subject based on the ideXlab platform.

  • a perspective on pse in pharmaceutical Process Development and innovation
    Computers & Chemical Engineering, 2012
    Co-Authors: Krist V Gernaey, Albert E Cerverapadrell, John M Woodley
    Abstract:

    Abstract The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in Process Development. This paper discusses the central role of Process Systems Engineering (PSE) methods and tools in pharmaceutical Process Development and innovation, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method Development needed? The paper covers key subjects for Development of economically and environmentally sustainable pharmaceutical Processes, including Process Analytical Technology in its broadest sense, continuous pharmaceutical manufacturing and green Processes, and is illustrated with a series of short examples taken from the literature and ongoing research projects.

  • A perspective on PSE in pharmaceutical Process Development and innovation
    Computers and Chemical Engineering, 2012
    Co-Authors: Krist V Gernaey, Albert E. Cervera-padrell, John M Woodley
    Abstract:

    The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in Process Development. This paper discusses the central role of Process Systems Engineering (PSE) methods and tools in pharmaceutical Process Development and innovation, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method Development needed? The paper covers key subjects for Development of economically and environmentally sustainable pharmaceutical Processes, including Process Analytical Technology in its broadest sense, continuous pharmaceutical manufacturing and green Processes, and is illustrated with a series of short examples taken from the literature and ongoing research projects. © 2012 Elsevier Ltd.

  • PSE in Pharmaceutical Process Development
    Computer-aided chemical engineering, 2011
    Co-Authors: Krist V Gernaey, Albert Emili Cervera Padrell, John M Woodley
    Abstract:

    Abstract The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in Process Development. This paper will discuss the use of Process Systems Engineering (PSE) methods in pharmaceutical Process Development, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method Development needed? The paper is illustrated with a series of short examples taken from the literature and ongoing research projects.

Krist V Gernaey - One of the best experts on this subject based on the ideXlab platform.

  • a perspective on pse in pharmaceutical Process Development and innovation
    Computers & Chemical Engineering, 2012
    Co-Authors: Krist V Gernaey, Albert E Cerverapadrell, John M Woodley
    Abstract:

    Abstract The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in Process Development. This paper discusses the central role of Process Systems Engineering (PSE) methods and tools in pharmaceutical Process Development and innovation, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method Development needed? The paper covers key subjects for Development of economically and environmentally sustainable pharmaceutical Processes, including Process Analytical Technology in its broadest sense, continuous pharmaceutical manufacturing and green Processes, and is illustrated with a series of short examples taken from the literature and ongoing research projects.

  • A perspective on PSE in pharmaceutical Process Development and innovation
    Computers and Chemical Engineering, 2012
    Co-Authors: Krist V Gernaey, Albert E. Cervera-padrell, John M Woodley
    Abstract:

    The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in Process Development. This paper discusses the central role of Process Systems Engineering (PSE) methods and tools in pharmaceutical Process Development and innovation, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method Development needed? The paper covers key subjects for Development of economically and environmentally sustainable pharmaceutical Processes, including Process Analytical Technology in its broadest sense, continuous pharmaceutical manufacturing and green Processes, and is illustrated with a series of short examples taken from the literature and ongoing research projects. © 2012 Elsevier Ltd.

  • PSE in Pharmaceutical Process Development
    Computer-aided chemical engineering, 2011
    Co-Authors: Krist V Gernaey, Albert Emili Cervera Padrell, John M Woodley
    Abstract:

    Abstract The pharmaceutical industry is under growing pressure to increase efficiency, both in production and in Process Development. This paper will discuss the use of Process Systems Engineering (PSE) methods in pharmaceutical Process Development, and searches for answers to questions such as: Which PSE methods can be applied readily? Where is more method Development needed? The paper is illustrated with a series of short examples taken from the literature and ongoing research projects.

Ashley Hesslein - One of the best experts on this subject based on the ideXlab platform.

  • Lessons learned in building high throughput Process Development capabilities
    Engineering in Life Sciences, 2016
    Co-Authors: Jennifer Pollard, Paul Mcdonald, Ashley Hesslein
    Abstract:

    Companies have adapted high throughput techniques for Process Development to different levels. Some companies are beginning to incorporate high throughput Process Development (HTPD) techniques at a level which is approachable for the beginner user (example: plate-based resin screening for purification) and others have sophisticated robotic platforms which are in routine use for new pipeline products for upstream, downstream, analytics, and just now starting in the protein formulation area. This mini review serves to summarize how companies have set up and are using HTPD capabilities, including the need for user-groups to improve the likelihood of success. The focus will be a practical summary of the utility and limitations of these approaches.This article is protected by copyright. All rights reserved.

Jennifer Pollard - One of the best experts on this subject based on the ideXlab platform.

  • Lessons learned in building high throughput Process Development capabilities
    Engineering in Life Sciences, 2016
    Co-Authors: Jennifer Pollard, Paul Mcdonald, Ashley Hesslein
    Abstract:

    Companies have adapted high throughput techniques for Process Development to different levels. Some companies are beginning to incorporate high throughput Process Development (HTPD) techniques at a level which is approachable for the beginner user (example: plate-based resin screening for purification) and others have sophisticated robotic platforms which are in routine use for new pipeline products for upstream, downstream, analytics, and just now starting in the protein formulation area. This mini review serves to summarize how companies have set up and are using HTPD capabilities, including the need for user-groups to improve the likelihood of success. The focus will be a practical summary of the utility and limitations of these approaches.This article is protected by copyright. All rights reserved.

Paul Mcdonald - One of the best experts on this subject based on the ideXlab platform.

  • Lessons learned in building high throughput Process Development capabilities
    Engineering in Life Sciences, 2016
    Co-Authors: Jennifer Pollard, Paul Mcdonald, Ashley Hesslein
    Abstract:

    Companies have adapted high throughput techniques for Process Development to different levels. Some companies are beginning to incorporate high throughput Process Development (HTPD) techniques at a level which is approachable for the beginner user (example: plate-based resin screening for purification) and others have sophisticated robotic platforms which are in routine use for new pipeline products for upstream, downstream, analytics, and just now starting in the protein formulation area. This mini review serves to summarize how companies have set up and are using HTPD capabilities, including the need for user-groups to improve the likelihood of success. The focus will be a practical summary of the utility and limitations of these approaches.This article is protected by copyright. All rights reserved.