The Experts below are selected from a list of 255 Experts worldwide ranked by ideXlab platform

Erkki Isometsä - One of the best experts on this subject based on the ideXlab platform.

  • Only half of bipolar I and II patients report Prodromal Symptoms.
    Journal of Affective Disorders, 2008
    Co-Authors: Outi Mantere, Kirsi Suominen, Hanna Valtonen, Petri Arvilommi, Erkki Isometsä
    Abstract:

    Abstract Background Learning to detect Prodromal Symptoms is a key element of psychosocial treatment of bipolar disorder (BD). However, previous studies have described only prodromes of manic and depressive phases of BD I patients, while information on prodromes in BD II, or other phases is lacking. Methods The Jorvi Bipolar Study included 191 in- and outpatients with DSM-IV BD (90 BD I, 101 BD II) in any acute phase of illness at baseline. The prevalence, type and duration of preceding prodromes were investigated using open-ended questions. The effects of type I or II disorder, index phase, socio-demographic factors, comorbidity, illness history and other correlates on report and duration of prodromes were investigated. Results Prodromes were reported by 45.0% of BD I and 50.0% of BD II patients. The first Prodromal Symptom was usually mood congruent, but sometimes non-specific for mood or a Symptom of anxiety; the median duration was 30.5 days. No differences between BD I and II, or between patients who did and those who did not report prodromes were found. Only Axis I comorbidity associated with longer prodromes, but not independently after adjusting for age, gender and type of phase. Limitations The study was cross-sectional. Reporting prodromes depends on patients' insight which was likely affected by a sub-acute phase at time of interview. Conclusions Only half of ordinary, secondary care bipolar patients are able to report prodromes. The chronic and fluctuating course of illness, and sometimes short time interval to full episode may limit the potentials of prodrome-based interventions.

  • Only half of bipolar I and II patients report Prodromal Symptoms.
    Journal of affective disorders, 2008
    Co-Authors: Outi Mantere, Kirsi Suominen, Petri Arvilommi, Hanna M Valtonen, Erkki Isometsä
    Abstract:

    Learning to detect Prodromal Symptoms is a key element of psychosocial treatment of bipolar disorder (BD). However, previous studies have described only prodromes of manic and depressive phases of BD I patients, while information on prodromes in BD II, or other phases is lacking. The Jorvi Bipolar Study included 191 in- and outpatients with DSM-IV BD (90 BD I, 101 BD II) in any acute phase of illness at baseline. The prevalence, type and duration of preceding prodromes were investigated using open-ended questions. The effects of type I or II disorder, index phase, socio-demographic factors, comorbidity, illness history and other correlates on report and duration of prodromes were investigated. Prodromes were reported by 45.0% of BD I and 50.0% of BD II patients. The first Prodromal Symptom was usually mood congruent, but sometimes non-specific for mood or a Symptom of anxiety; the median duration was 30.5 days. No differences between BD I and II, or between patients who did and those who did not report prodromes were found. Only Axis I comorbidity associated with longer prodromes, but not independently after adjusting for age, gender and type of phase. The study was cross-sectional. Reporting prodromes depends on patients' insight which was likely affected by a sub-acute phase at time of interview. Only half of ordinary, secondary care bipolar patients are able to report prodromes. The chronic and fluctuating course of illness, and sometimes short time interval to full episode may limit the potentials of prodrome-based interventions.

Marco Schlosser - One of the best experts on this subject based on the ideXlab platform.

  • repetitive negative thinking is associated with subjective cognitive decline in older adults a cross sectional study
    BMC Psychiatry, 2020
    Co-Authors: Marco Schlosser, Harriet Demnitzking, Tim Whitfield, Miranka Wirth, Natalie L Marchant
    Abstract:

    In the absence of a cure or effective treatment for dementia, attention has shifted towards identifying risk factors for prevention. Subjective Cognitive Decline (SCD) describes self-perceived worsening of cognition despite unimpaired performance on neuropsychological tests. SCD has been associated with an increased dementia risk and steeper memory decline. Repetitive negative thinking (RNT) is a transdiagnostic process that manifests across several mental health disorders associated with increased vulnerability to dementia. RNT has thus been proposed as a candidate marker of risk for dementia and, relatedly, could contribute to the manifestation of SCD. We aimed to investigate the relationship between SCD and RNT alongside other proposed psychological risk/protective factors for dementia and cognitive decline. In a cross-sectional online survey, 491 older adults (mean = 64.9 years, SD = 4.2; 63.1% female) completed measures of RNT, personality traits, purpose in life, worry, rumination, and meditation practice. SCD was assessed continuously via self-perceived cognitive function (Neuro-QoL) and categorically via endorsement (yes/no) of memory complaints. Regression models, using a stepwise backwards elimination, were built to assess associations between SCD, demographics, and all risk/protective factors. A total of 24.2% of participants reported memory complaints. In the final prediction models, RNT was the only psychological variable associated with lower self-perceived cognitive function and with a higher likelihood of memory complaints. This study empirically corroborates the theoretical relationship between SCD and RNT. Longitudinal studies are needed to establish whether RNT is a Prodromal Symptom or an independent risk factor, and whether RNT can be a promising construct for future research on SCD and dementia risk.

  • repetitive negative thinking is associated with subjective cognitive decline in older adults a cross sectional study
    BMC Psychiatry, 2020
    Co-Authors: Marco Schlosser, Harriet Demnitzking, Tim Whitfield, Miranka Wirth, Natalie L Marchant
    Abstract:

    Background In the absence of a cure or effective treatment for dementia, attention has shifted towards identifying risk factors for prevention. Subjective Cognitive Decline (SCD) describes self-perceived worsening of cognition despite unimpaired performance on neuropsychological tests. SCD has been associated with an increased dementia risk and steeper memory decline. Repetitive negative thinking (RNT) is a transdiagnostic process that manifests across several mental health disorders associated with increased vulnerability to dementia. RNT has thus been proposed as a candidate marker of risk for dementia and, relatedly, could contribute to the manifestation of SCD. We aimed to investigate the relationship between SCD and RNT alongside other proposed psychological risk/protective factors for dementia and cognitive decline. Methods In a cross-sectional online survey, 491 older adults (mean = 64.9 years, SD = 4.2; 63.1% female) completed measures of RNT, personality traits, purpose in life, worry, rumination, and meditation practice. SCD was assessed continuously via self-perceived cognitive function (Neuro-QoL) and categorically via endorsement (yes/no) of memory complaints. Regression models, using a stepwise backwards elimination, were built to assess associations between SCD, demographics, and all risk/protective factors. Results A total of 24.2% of participants reported memory complaints. In the final prediction models, RNT was the only psychological variable associated with lower self-perceived cognitive function and with a higher likelihood of memory complaints. Conclusions This study empirically corroborates the theoretical relationship between SCD and RNT. Longitudinal studies are needed to establish whether RNT is a Prodromal Symptom or an independent risk factor, and whether RNT can be a promising construct for future research on SCD and dementia risk.

Natalie L Marchant - One of the best experts on this subject based on the ideXlab platform.

  • repetitive negative thinking is associated with subjective cognitive decline in older adults a cross sectional study
    BMC Psychiatry, 2020
    Co-Authors: Marco Schlosser, Harriet Demnitzking, Tim Whitfield, Miranka Wirth, Natalie L Marchant
    Abstract:

    In the absence of a cure or effective treatment for dementia, attention has shifted towards identifying risk factors for prevention. Subjective Cognitive Decline (SCD) describes self-perceived worsening of cognition despite unimpaired performance on neuropsychological tests. SCD has been associated with an increased dementia risk and steeper memory decline. Repetitive negative thinking (RNT) is a transdiagnostic process that manifests across several mental health disorders associated with increased vulnerability to dementia. RNT has thus been proposed as a candidate marker of risk for dementia and, relatedly, could contribute to the manifestation of SCD. We aimed to investigate the relationship between SCD and RNT alongside other proposed psychological risk/protective factors for dementia and cognitive decline. In a cross-sectional online survey, 491 older adults (mean = 64.9 years, SD = 4.2; 63.1% female) completed measures of RNT, personality traits, purpose in life, worry, rumination, and meditation practice. SCD was assessed continuously via self-perceived cognitive function (Neuro-QoL) and categorically via endorsement (yes/no) of memory complaints. Regression models, using a stepwise backwards elimination, were built to assess associations between SCD, demographics, and all risk/protective factors. A total of 24.2% of participants reported memory complaints. In the final prediction models, RNT was the only psychological variable associated with lower self-perceived cognitive function and with a higher likelihood of memory complaints. This study empirically corroborates the theoretical relationship between SCD and RNT. Longitudinal studies are needed to establish whether RNT is a Prodromal Symptom or an independent risk factor, and whether RNT can be a promising construct for future research on SCD and dementia risk.

  • repetitive negative thinking is associated with subjective cognitive decline in older adults a cross sectional study
    BMC Psychiatry, 2020
    Co-Authors: Marco Schlosser, Harriet Demnitzking, Tim Whitfield, Miranka Wirth, Natalie L Marchant
    Abstract:

    Background In the absence of a cure or effective treatment for dementia, attention has shifted towards identifying risk factors for prevention. Subjective Cognitive Decline (SCD) describes self-perceived worsening of cognition despite unimpaired performance on neuropsychological tests. SCD has been associated with an increased dementia risk and steeper memory decline. Repetitive negative thinking (RNT) is a transdiagnostic process that manifests across several mental health disorders associated with increased vulnerability to dementia. RNT has thus been proposed as a candidate marker of risk for dementia and, relatedly, could contribute to the manifestation of SCD. We aimed to investigate the relationship between SCD and RNT alongside other proposed psychological risk/protective factors for dementia and cognitive decline. Methods In a cross-sectional online survey, 491 older adults (mean = 64.9 years, SD = 4.2; 63.1% female) completed measures of RNT, personality traits, purpose in life, worry, rumination, and meditation practice. SCD was assessed continuously via self-perceived cognitive function (Neuro-QoL) and categorically via endorsement (yes/no) of memory complaints. Regression models, using a stepwise backwards elimination, were built to assess associations between SCD, demographics, and all risk/protective factors. Results A total of 24.2% of participants reported memory complaints. In the final prediction models, RNT was the only psychological variable associated with lower self-perceived cognitive function and with a higher likelihood of memory complaints. Conclusions This study empirically corroborates the theoretical relationship between SCD and RNT. Longitudinal studies are needed to establish whether RNT is a Prodromal Symptom or an independent risk factor, and whether RNT can be a promising construct for future research on SCD and dementia risk.

Outi Mantere - One of the best experts on this subject based on the ideXlab platform.

  • Only half of bipolar I and II patients report Prodromal Symptoms.
    Journal of Affective Disorders, 2008
    Co-Authors: Outi Mantere, Kirsi Suominen, Hanna Valtonen, Petri Arvilommi, Erkki Isometsä
    Abstract:

    Abstract Background Learning to detect Prodromal Symptoms is a key element of psychosocial treatment of bipolar disorder (BD). However, previous studies have described only prodromes of manic and depressive phases of BD I patients, while information on prodromes in BD II, or other phases is lacking. Methods The Jorvi Bipolar Study included 191 in- and outpatients with DSM-IV BD (90 BD I, 101 BD II) in any acute phase of illness at baseline. The prevalence, type and duration of preceding prodromes were investigated using open-ended questions. The effects of type I or II disorder, index phase, socio-demographic factors, comorbidity, illness history and other correlates on report and duration of prodromes were investigated. Results Prodromes were reported by 45.0% of BD I and 50.0% of BD II patients. The first Prodromal Symptom was usually mood congruent, but sometimes non-specific for mood or a Symptom of anxiety; the median duration was 30.5 days. No differences between BD I and II, or between patients who did and those who did not report prodromes were found. Only Axis I comorbidity associated with longer prodromes, but not independently after adjusting for age, gender and type of phase. Limitations The study was cross-sectional. Reporting prodromes depends on patients' insight which was likely affected by a sub-acute phase at time of interview. Conclusions Only half of ordinary, secondary care bipolar patients are able to report prodromes. The chronic and fluctuating course of illness, and sometimes short time interval to full episode may limit the potentials of prodrome-based interventions.

  • Only half of bipolar I and II patients report Prodromal Symptoms.
    Journal of affective disorders, 2008
    Co-Authors: Outi Mantere, Kirsi Suominen, Petri Arvilommi, Hanna M Valtonen, Erkki Isometsä
    Abstract:

    Learning to detect Prodromal Symptoms is a key element of psychosocial treatment of bipolar disorder (BD). However, previous studies have described only prodromes of manic and depressive phases of BD I patients, while information on prodromes in BD II, or other phases is lacking. The Jorvi Bipolar Study included 191 in- and outpatients with DSM-IV BD (90 BD I, 101 BD II) in any acute phase of illness at baseline. The prevalence, type and duration of preceding prodromes were investigated using open-ended questions. The effects of type I or II disorder, index phase, socio-demographic factors, comorbidity, illness history and other correlates on report and duration of prodromes were investigated. Prodromes were reported by 45.0% of BD I and 50.0% of BD II patients. The first Prodromal Symptom was usually mood congruent, but sometimes non-specific for mood or a Symptom of anxiety; the median duration was 30.5 days. No differences between BD I and II, or between patients who did and those who did not report prodromes were found. Only Axis I comorbidity associated with longer prodromes, but not independently after adjusting for age, gender and type of phase. The study was cross-sectional. Reporting prodromes depends on patients' insight which was likely affected by a sub-acute phase at time of interview. Only half of ordinary, secondary care bipolar patients are able to report prodromes. The chronic and fluctuating course of illness, and sometimes short time interval to full episode may limit the potentials of prodrome-based interventions.

Mohammad Ali Sadr-ameli - One of the best experts on this subject based on the ideXlab platform.

  • Can Prodromal Symptoms predict recurrence of vasovagal syncope
    Cardiology journal, 2008
    Co-Authors: Amir Farjam Fazelifar, Hosein Ali Basiri, Ali Tolooie, Majid Haghjoo, Hamid Barakpour, Zahra Emkanjoo, Hooman Bakhshandeh Abkenar, Mahboubeh Zeighami, Foroozan Asgari, Mohammad Ali Sadr-ameli
    Abstract:

    Background: Vasovagal syncope (VVS) is a common Symptom with empirical therapy and high recurrence rate. Our goal was to determine whether the pattern of presyncopal Prodromal Symptoms can predict the recurrence probability of vasovagal syncope. Methods: Seventy-nine consecutive patients (male/female: 53/26) with history of VVS and positive tilt table test (TTT) were enrolled in the study and completed the follow-up time for one year. They all had normal electrocardiograms and cardiac echocardiography without underlying disease. All of them were evaluated meticulously for Prodromal Symptoms (diaphoresis, nausea, palpitation and blurred vision) and frequency of syncopal spells in their past medical history. They received metoprolol at maximum tolerated dose and were taught tilt training as an empirical therapy after TTT. Results: Fifty-four patients (68.4%) reported at least one of the four main Prodromal Symptoms. Median syncopal ± presyncopal spells were 4 episodes. Forty-two patients (53.2%) experienced recurrence of syncope or presyncope during the follow-up period. In recurrent Symptomatic patients, diaphoresis had been more significantly reported in their past medical history (p = 0.018) and they had more syncopal spells before TTT (p = 0.001). Age, gender and type of TTT response did not have any effect on the recurrence of VVS. Conclusions: Patients with a history of diaphoresis as a Prodromal Symptom and more pretilt syncopal attacks experience more syncopal or presyncopal spells during follow-up.