The Experts below are selected from a list of 582 Experts worldwide ranked by ideXlab platform
Nadia Rentia - One of the best experts on this subject based on the ideXlab platform.
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
Paraskevi Xekouki - One of the best experts on this subject based on the ideXlab platform.
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
Eva Szarek - One of the best experts on this subject based on the ideXlab platform.
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
Petra Bullova - One of the best experts on this subject based on the ideXlab platform.
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
Spyridon A Mastroyannis - One of the best experts on this subject based on the ideXlab platform.
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
-
pituitary adenoma with paraganglioma pheochromocytoma 3pas and succinate dehydrogenase defects in humans and mice
The Journal of Clinical Endocrinology and Metabolism, 2015Co-Authors: Paraskevi Xekouki, Eva Szarek, Petra Bullova, Spyridon A Mastroyannis, Margarita Raygada, Alessio Giubellino, Panagiotis Mastorakos, Martha Quezado, Christopher A Wassif, Nadia RentiaAbstract:Context: Germline mutations in genes coding succinate dehydrogenase (SDH) subunits A, B, C, and D have been identified in familial paragangliomas (PGLs)/pheochromocytomas (PHEOs) and other tumors. We described a GH-Secreting pituitary adenoma (PA) caused by SDHD mutation in a patient with familial PGLs. Additional patients with PAs and SDHx defects have since been reported. Design: We studied 168 patients with unselected sporadic PA and with the association of PAs, PGLs, and/or pheochromocytomas, a condition we named the 3P association (3PAs) for SDHx germline mutations. We also studied the pituitary gland and hormonal profile of Sdhb+/− mice and their wild-type littermates at different ages. Results: No SDHx mutations were detected among sporadic PA, whereas three of four familial cases were positive for a mutation (75%). Most of the SDHx-deficient PAs were either Prolactinomas or somatotropinomas. Pituitaries of Sdhb+/− mice older than 12 months had an increased number mainly of Prolactin-Secreting Cell...
