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Adeyiza O. Momoh - One of the best experts on this subject based on the ideXlab platform.
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breast cancer knowledge and decisions made for contralateral Prophylactic Mastectomy a survey of surgeons and women in the general population
Plastic and Reconstructive Surgery, 2019Co-Authors: Rachel C Hooper, Anthony Duncan, Kevin C. Chung, Lisa A Newman, Jessica Bensenhaver, Kelly M Kidwell, Adeyiza O. MomohAbstract:BACKGROUND: Decisions made to undergo contralateral Prophylactic Mastectomy, in women at low risk for bilateral disease, are often attributed to a lack of knowledge. This study examines the role knowledge plays in determining surgical treatment for unilateral breast cancer made by laywomen and surgeons for themselves or loved ones. METHODS: The study cohort had three groups: (1) laywomen in the general population, (2) breast surgeons, and (3) plastic surgeons. Laywomen were recruited using Amazon Mechanical Turk Crowd Sourcing. Breast and plastic surgeons from nine states were sent electronic surveys. Demographic and contralateral Prophylactic Mastectomy-specific data on decisions and knowledge were collected and analyzed. RESULTS: Surveys from 1333 laywomen, 198 plastic surgeons, and 142 breast surgeons were analyzed. A significantly greater proportion of laywomen in the general population favored contralateral Prophylactic Mastectomy (67 percent) relative to plastic (50 percent) and breast surgeons (26 percent) (p < 0.0001). Breast surgeons who chose contralateral Prophylactic Mastectomy were younger (p = 0.044) and female (0.012). On assessment of knowledge, 78 percent of laywomen had a low level of breast cancer knowledge. Laywomen with higher levels of breast cancer knowledge had lower odds of choosing contralateral Prophylactic Mastectomy (OR, 0.37; 95 percent CI, 0.28 to 0.49). CONCLUSIONS: Fewer women are likely to make decisions in favor of contralateral Prophylactic Mastectomy with better breast cancer-specific education. A knowledge gap likely explains the lower rates with which surgeons choose contralateral Prophylactic Mastectomy for themselves or loved ones; however, some surgeons who were predominantly young and female favor contralateral Prophylactic Mastectomy. Improving patient education on surgical options for breast cancer treatment is critical, with well-informed decisions as the goal.
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The Cost of Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer
Plastic and Reconstructive Surgery, 2018Co-Authors: Jessica I. Billig, Anthony Duncan, Lin Zhong, Oluseyi Aliu, Erika D. Sears, Kevin C. Chung, Adeyiza O. MomohAbstract:BACKGROUND: Contralateral Prophylactic Mastectomy may be unnecessary from an oncologic perspective; therefore, the debate persists about the value of contralateral Prophylactic Mastectomy in women with early-stage unilateral breast cancer. Given finite health care resources, this study aims to evaluate the cost of contralateral Prophylactic Mastectomy and breast reconstruction. METHODS: Women with unilateral breast cancer undergoing either unilateral Mastectomy or unilateral Mastectomy with contralateral Prophylactic Mastectomy and immediate breast reconstruction were selected from the Truven MarketScan databases between 2009 and 2013. Demographic and treatment data were recorded, and over an 18-month follow-up period, the treatment cost was tallied. A log-transformed linear model was used to compare cost between the groups. RESULTS: A total of 2343 women were identified who met our inclusion criteria, with 1295 undergoing unilateral Mastectomy and 1048 undergoing contralateral Prophylactic Mastectomy. Complication rates within 18 months were similar for women undergoing unilateral Mastectomy and contralateral Prophylactic Mastectomy (39 percent versus 42 percent; p = 0.17). Management with unilateral Mastectomy with reconstruction required an adjusted cumulative mean cost of $33,557. Contralateral Prophylactic Mastectomy with reconstruction was an additional $11,872 in expenditure (p < 0.001). The cost of initial procedures (mean difference, $6467) and secondary procedures (mean difference, $2455) were the greatest contributors to cost. CONCLUSIONS: In women with unilateral breast cancer, contralateral Prophylactic Mastectomy with reconstruction is more costly. The increased monetary cost of contralateral Prophylactic Mastectomy may be offset by improved quality of life. However, this financial reality is an important consideration when ongoing efforts toward reimbursement reform may not pay for contralateral Prophylactic Mastectomy if outcomes data are not presented to justify this procedure.
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An Evaluation of the Choice for Contralateral Prophylactic Mastectomy and Patient Concerns About Recurrence in a Reconstructed Cohort.
Annals of Plastic Surgery, 2017Co-Authors: Ian C. Sando, Jessica I. Billig, Lin Zhong, Kevin C. Chung, Shoshana W. Ambani, Casey T. Kraft, Kelley M. Kidwell, Adeyiza O. MomohAbstract:BACKGROUND: Rising contralateral Prophylactic Mastectomy rates are a subject of national concern. This study assessed (1) factors critical to patients when deciding on contralateral Prophylactic Mastectomy and (2) patients' quality of life related to concerns about recurrence after unilateral or bilateral breast reconstruction. METHODS: Patients with stage 0 to III breast cancer who underwent unilateral Mastectomy or contralateral Prophylactic Mastectomy and breast reconstruction at a single institution between 2000 and 2012 were identified. Demographic and clinical data were extracted by chart review. Women's fears about breast cancer recurrence were assessed using the Concerns About Recurrence Scale, and motivational factors for contralateral Prophylactic Mastectomy were identified using the Decisions for Contralateral Prophylactic Mastectomy Survey. RESULTS: Survey responses were received from 157 patients (59%) who underwent unilateral reconstruction and 109 (41%) who underwent bilateral reconstruction. The top 3 reasons for choosing contralateral Prophylactic Mastectomy were (1) decreasing the risk of contralateral breast disease (97%), (2) peace of mind (96%), and (3) improved survival (93%). Women who chose contralateral Prophylactic Mastectomy reported significantly greater overall fear and worry compared with the unilateral group, specifically, greater fears of dying and worries about adequately fulfilling roles of daily life (P < 0.05). CONCLUSIONS: Despite no proven survival benefit, women chose contralateral Prophylactic Mastectomy primarily to optimize oncologic outcomes. Among breast reconstruction patients, women who underwent contralateral Prophylactic Mastectomy had greater anxiety and overall fear of breast cancer recurrence compared with those who chose unilateral Mastectomy. These findings are important to consider when counseling women contemplating contralateral Prophylactic Mastectomy.
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an analysis of the decisions made for contralateral Prophylactic Mastectomy and breast reconstruction
Plastic and Reconstructive Surgery, 2016Co-Authors: Patrick J Buchanan, Kevin C. Chung, Mariam Abdulghani, Jennifer F Waljee, Jeffrey H Kozlow, Michael S Sabel, Lisa A Newman, Adeyiza O. MomohAbstract:Background: Little is known about the role breast reconstruction plays in decisions made for contralateral Prophylactic Mastectomy. This study explores factors critical to patient medical decision-making for contralateral Prophylactic Mastectomy and reconstruction among women with early stage, unilateral breast cancer. Methods: A mixed methods approach was used to gain an understanding of patients’ choices and experiences. Patients with stage 0 to III unilateral breast cancer who underwent reconstruction were recruited, and semistructured interviews were conducted. Patient-reported outcomes were evaluated using the Concerns About Recurrence Scale and the BREAST-Q. Results: Thirty patients were enrolled; 13 (43 percent) underwent unilateral Mastectomy and 17 (57 percent) underwent contralateral Prophylactic Mastectomy. Three broad categories emerged from patient interviews: medical decision-making, quality of life after Mastectomy, and breast reconstruction expectations. Patients who chose contralateral Prophylactic Mastectomy made the decision for Mastectomy based primarily on worry about recurrence. Quality of life after Mastectomy was characterized by relief of worry, especially in patients who chose contralateral Prophylactic Mastectomy [n = 14 (82.4 percent)]. Patients’ desires for symmetry, although not the primary reason for contralateral Prophylactic Mastectomy, played a role in supporting decisions made. Levels of worry after treatment were similar in both groups (72.7 percent). Patients with contralateral Prophylactic Mastectomy had higher mean scores for satisfaction with breast (82.4 versus 70.6) and satisfaction with outcome (89.9 versus 75.2). Conclusions: The choice for contralateral Prophylactic Mastectomy is greatly influenced by fear of recurrence, with desires for symmetry playing a secondary role in decisions made.
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defining the relationship between patient decisions to undergo breast reconstruction and contralateral Prophylactic Mastectomy
Plastic and Reconstructive Surgery, 2015Co-Authors: Shailesh Agarwal, Kevin C. Chung, Jeffrey H Kozlow, Michael S Sabel, Casey T. Kraft, Kelley M. Kidwell, Adeyiza O. MomohAbstract:Background:Recent studies suggest that the decisions to undergo breast reconstruction and contralateral Prophylactic Mastectomy are closely related. In this article, the relationship between method of reconstruction and decision to undergo contralateral Prophylactic Mastectomy is described. Recent t
Ann M Geiger - One of the best experts on this subject based on the ideXlab platform.
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what women wish they knew before Prophylactic Mastectomy
Cancer Nursing, 2007Co-Authors: Sharon J Rolnick, Mary B Barton, Emily L Harris, Joann G Elmore, Lisa J Herrinton, Sarah M Greene, Larissa Nekhlyudov, Ann M Geiger, Andrea Altschuler, Suzanne W FletcherAbstract:Breast cancerInformational needsProphylactic MastectomyAlthough Prophylactic Mastectomy significantly reduces the incidence andrecurrence of breast cancer, little is known about women’s information needs beforethe procedure. We surveyed 967 women, from 6 healthcare systems, with bilateralor contralateral Prophylactic Mastectomy performed between 1979 and 1999.There were 2 open-ended questions: ‘‘What one thing do you wish you had knownbefore your Prophylactic Mastectomy’’ and ‘‘Is there anything else you would like toshare with us?’’ Three researchers categorized responses, and informational needswere ascertained. Seventy-one percent (684 women) responded, of which 81%answered one or both open-ended questions. There were 386 comments (made by293 women) that related to information needs; 79% of women had bilateralProphylactic Mastectomy and 58% had contralateral Prophylactic Mastectomy.Most concerns (69%) were related to reconstruction: the longevity; look and feel ofimplants, pain, numbness, scarring, and reconstruction options. Many womenwished they had seen photographs to better prepare them for the final result. Ourfindings suggest that information needs of many women undergoing ProphylacticMastectomy, particularly those selecting bilateral Prophylactic Mastectomy, have notbeen sufficiently addressed. Clinicians and health educators should be aware ofpatient needs and must counsel women accordingly.Prophylactic Mastectomy
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quality of life after bilateral Prophylactic Mastectomy
Annals of Surgical Oncology, 2007Co-Authors: Carmen N West, Emily L Harris, Sharon J Rolnick, Lisa J Herrinton, Sarah M Greene, Larissa Nekhlyudov, Ann M Geiger, Joann G ElmoreAbstract:Background Bilateral Prophylactic Mastectomy in women with increased breast cancer risk dramatically reduces breast cancer occurrence but little is known about psychosocial outcomes.
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complications following bilateral Prophylactic Mastectomy
Journal of The National Cancer Institute Monographs, 2005Co-Authors: Mary B Barton, Carmen N West, Emily L Harris, Sharon J Rolnick, Joann G Elmore, Lisa J Herrinton, Sarah M Greene, Larissa Nekhlyudov, Suzanne W Fletcher, Ann M GeigerAbstract:Background: Bilateral Prophylactic Mastectomy signifi cantly decreases breast cancer risk, but complications of the procedure have only been described in single-site studies. We describe the frequency and type of complications in women who underwent bilateral Prophylactic Mastectomy in a multisite community-based cohort. Methods: Women aged 18 – 80 years undergoing bilateral Prophylactic Mastectomy without a personal history of breast cancer at one of six health plans were eligible. We identifi ed women from automated data sources, then reviewed hospital data, ambulatory notes, and other chart elements to confi rm eligibility and obtain all charted information about complications and surgeries performed after Prophylactic Mastectomy, including reconstructive procedures. Reconstructions were characterized by type (implant vs. tissue graft). Complications were noted for a 1-year period after any surgical procedure. Results: We identifi ed 269 women with Prophylactic Mastectomy who were followed for a mean of 7.4 years. Their mean age was 44.9 years. Nearly 80% undertook reconstruction, most with prosthetic implants. One or more complications occurred in 64%. The most common complications were pain (35% of women), infection (17%), and seroma (17%). Women with no reconstruction had fewer complications (mean of .93) than women who had implant (2.0) or tissue graft (2.4) reconstruction procedures (differences from no reconstruction: 1.07 [95% confi dence interval = 0.36 to 1.77] and 1.50 [95% con fi dence interval = 0.44 to 2.56] respectively). Delay of reconstruction after Mastectomy was associated with a borderline-signifi cant higher risk of complications (80.6%) compared to simultaneous reconstruction (64.0%, P = .055). Conclusion: We found that almost two-thirds of women undergoing bilateral Prophylactic Mastectomy had at least one complication following surgery. Further work should be done to minimize and to understand the effect of complications of bilateral Prophylactic Mastectomy. [J Natl Cancer Inst Monogr 2005;35:61 – 6]
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a population based study of bilateral Prophylactic Mastectomy efficacy in women at elevated risk for breast cancer in community practices
JAMA Internal Medicine, 2005Co-Authors: Ann M Geiger, Mary B Barton, Emily L Harris, Sharon J Rolnick, Joann G Elmore, Lisa J Herrinton, Onchee Yu, William E Barlow, Suzanne W FletcherAbstract:Results:Breast cancer developed in 1 woman (0.4%) after bilateral Prophylactic Mastectomy vs 26800 women (4.0%) without Prophylactic Mastectomy. Stratifying by birth year, the hazard ratio for breast cancer occurrence after bilateral Prophylactic Mastectomy was 0.005 (95% confidence interval, 0.001-0.044). No woman with bilateral Prophylactic Mastectomy died of breast cancer vs a calculated 0.2% of women without Prophylactic Mastectomy.
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Are women satisfied after Prophylactic Mastectomy
Journal of Clinical Oncology, 2004Co-Authors: Ann M Geiger, Carmen N West, G. Wolde-tsadikAbstract:6048 Background: Bilateral Prophylactic Mastectomy in women with increased breast cancer risk and contralateral Prophylactic Mastectomy in women with unilateral breast cancer dramatically reduce th...
Suzanne W Fletcher - One of the best experts on this subject based on the ideXlab platform.
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positive negative and disparate women s differing long term psychosocial experiences of bilateral or contralateral Prophylactic Mastectomy
Breast Journal, 2008Co-Authors: Andrea Altschuler, Carmen N West, Emily L Harris, Sharon J Rolnick, Joann G Elmore, Lisa J Herrinton, Sarah M Greene, Larissa Nekhlyudov, Suzanne W Fletcher, Karen M EmmonsAbstract:Abstract: Because of recent studies showing strong prevention benefit and acceptable psychosocial outcomes, more women may be considering Prophylactic Mastectomy. A growing literature shows some positive psychosocial outcomes for women with bilateral Prophylactic Mastectomy, but less is known about women with contralateral Prophylactic Mastectomy. Several surveys have shown that a large majority of women with Prophylactic Mastectomy report satisfaction with their decisions to have the procedure when asked in a quantitative, closed-ended format. We sought to explore the nuances of women’s satisfaction with the procedure using a qualitative, open-ended format. We included open-ended questions as part of a mailed survey on psychosocial outcomes of Prophylactic Mastectomy. The research team coded and analyzed these responses using qualitative methods. We used simple descriptive statistics to compare the demographics of the entire survey sample to those women who answered the open-ended questions; the responses to the open- and closed-ended satisfaction questions, and the responses of women with bilateral and contralateral Prophylactic Mastectomy. Seventy-one percent of women with Prophylactic Mastectomy responded to the survey and 48% provided open-ended responses about psychosocial outcomes. Women’s open-ended responses regarding psychosocial outcomes could be coded into one of three general categories—positive, negative, and disparate. In the subgroup of women with both open-and closed-ended responses, over 70% of women providing negative and disparate comments to the open-ended question simultaneously indicated satisfaction on a closed-ended question. Negative and disparate open-ended responses were twice as common among women with bilateral Prophylactic Mastectomy (52%) than women with contralateral Prophylactic Mastectomy (26%). These findings suggest that even among women who report general satisfaction with their decision to have Prophylactic Mastectomy via closed-ended survey questions, lingering negative psychosocial outcomes can remain, particularly among women with bilateral Prophylactic Mastectomy. This dichotomy could be an important factor to discuss in counseling women considering the procedure.
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what women wish they knew before Prophylactic Mastectomy
Cancer Nursing, 2007Co-Authors: Sharon J Rolnick, Mary B Barton, Emily L Harris, Joann G Elmore, Lisa J Herrinton, Sarah M Greene, Larissa Nekhlyudov, Ann M Geiger, Andrea Altschuler, Suzanne W FletcherAbstract:Breast cancerInformational needsProphylactic MastectomyAlthough Prophylactic Mastectomy significantly reduces the incidence andrecurrence of breast cancer, little is known about women’s information needs beforethe procedure. We surveyed 967 women, from 6 healthcare systems, with bilateralor contralateral Prophylactic Mastectomy performed between 1979 and 1999.There were 2 open-ended questions: ‘‘What one thing do you wish you had knownbefore your Prophylactic Mastectomy’’ and ‘‘Is there anything else you would like toshare with us?’’ Three researchers categorized responses, and informational needswere ascertained. Seventy-one percent (684 women) responded, of which 81%answered one or both open-ended questions. There were 386 comments (made by293 women) that related to information needs; 79% of women had bilateralProphylactic Mastectomy and 58% had contralateral Prophylactic Mastectomy.Most concerns (69%) were related to reconstruction: the longevity; look and feel ofimplants, pain, numbness, scarring, and reconstruction options. Many womenwished they had seen photographs to better prepare them for the final result. Ourfindings suggest that information needs of many women undergoing ProphylacticMastectomy, particularly those selecting bilateral Prophylactic Mastectomy, have notbeen sufficiently addressed. Clinicians and health educators should be aware ofpatient needs and must counsel women accordingly.Prophylactic Mastectomy
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complications following bilateral Prophylactic Mastectomy
Journal of The National Cancer Institute Monographs, 2005Co-Authors: Mary B Barton, Carmen N West, Emily L Harris, Sharon J Rolnick, Joann G Elmore, Lisa J Herrinton, Sarah M Greene, Larissa Nekhlyudov, Suzanne W Fletcher, Ann M GeigerAbstract:Background: Bilateral Prophylactic Mastectomy signifi cantly decreases breast cancer risk, but complications of the procedure have only been described in single-site studies. We describe the frequency and type of complications in women who underwent bilateral Prophylactic Mastectomy in a multisite community-based cohort. Methods: Women aged 18 – 80 years undergoing bilateral Prophylactic Mastectomy without a personal history of breast cancer at one of six health plans were eligible. We identifi ed women from automated data sources, then reviewed hospital data, ambulatory notes, and other chart elements to confi rm eligibility and obtain all charted information about complications and surgeries performed after Prophylactic Mastectomy, including reconstructive procedures. Reconstructions were characterized by type (implant vs. tissue graft). Complications were noted for a 1-year period after any surgical procedure. Results: We identifi ed 269 women with Prophylactic Mastectomy who were followed for a mean of 7.4 years. Their mean age was 44.9 years. Nearly 80% undertook reconstruction, most with prosthetic implants. One or more complications occurred in 64%. The most common complications were pain (35% of women), infection (17%), and seroma (17%). Women with no reconstruction had fewer complications (mean of .93) than women who had implant (2.0) or tissue graft (2.4) reconstruction procedures (differences from no reconstruction: 1.07 [95% confi dence interval = 0.36 to 1.77] and 1.50 [95% con fi dence interval = 0.44 to 2.56] respectively). Delay of reconstruction after Mastectomy was associated with a borderline-signifi cant higher risk of complications (80.6%) compared to simultaneous reconstruction (64.0%, P = .055). Conclusion: We found that almost two-thirds of women undergoing bilateral Prophylactic Mastectomy had at least one complication following surgery. Further work should be done to minimize and to understand the effect of complications of bilateral Prophylactic Mastectomy. [J Natl Cancer Inst Monogr 2005;35:61 – 6]
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a population based study of bilateral Prophylactic Mastectomy efficacy in women at elevated risk for breast cancer in community practices
JAMA Internal Medicine, 2005Co-Authors: Ann M Geiger, Mary B Barton, Emily L Harris, Sharon J Rolnick, Joann G Elmore, Lisa J Herrinton, Onchee Yu, William E Barlow, Suzanne W FletcherAbstract:Results:Breast cancer developed in 1 woman (0.4%) after bilateral Prophylactic Mastectomy vs 26800 women (4.0%) without Prophylactic Mastectomy. Stratifying by birth year, the hazard ratio for breast cancer occurrence after bilateral Prophylactic Mastectomy was 0.005 (95% confidence interval, 0.001-0.044). No woman with bilateral Prophylactic Mastectomy died of breast cancer vs a calculated 0.2% of women without Prophylactic Mastectomy.
Steven A. Narod - One of the best experts on this subject based on the ideXlab platform.
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Predictors of quality of life in women with a bilateral Prophylactic Mastectomy.
Breast Journal, 2020Co-Authors: Kelly A. Metcalfe, Mary Jane Esplen, Vivek Goel, Steven A. NarodAbstract:: The purpose of this study was to assess the quality of life in women who had previously undergone a bilateral Prophylactic Mastectomy and to determine what factors predict quality of life in this population. Women in Ontario who had undergone Prophylactic Mastectomy between 1991 and 2000 were asked to complete several questionnaires that assessed current psychosocial functioning, including the Quality of Life Index (QLI). The mean score for the QLI was 23.34 (range 9.53–30.00). QLI scores were negatively correlated with cancer-related distress, body image difficulties, and psychological distress. Conversely, QLI scores were positively correlated with social support. Significant predictors of quality of life included psychological distress and one subscale of body image (vulnerability). Vulnerability and psychological distress are important predictors of quality of life in women who have previously undergone bilateral Prophylactic Mastectomy.
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bilateral Prophylactic Mastectomy reduces breast cancer risk in brca1 and brca2 mutation carriers the prose study group
Journal of Clinical Oncology, 2004Co-Authors: Timothy R Rebbeck, Judy Garber, Steven A. Narod, Henry T Lynch, Tara M Friebel, Susan L Neuhausen, Laura Van T Veer, Gareth D Evans, Claudine Isaacs, Ellen T MatloffAbstract:Purpose Data on the efficacy of bilateral Prophylactic Mastectomy for breast cancer risk reduction in women with BRCA1 and BRCA2 (BRCA1/2) mutations are limited, despite the clinical use of this risk-management strategy. Thus, we estimated the degree of breast cancer risk reduction after surgery in women who carry these mutations. Patients and Methods Four hundred eighty-three women with disease-associated germline BRCA1/2 mutations were studied for the occurrence of breast cancer. Cases were mutation carriers who underwent bilateral Prophylactic Mastectomy and who were followed prospectively from the time of their center ascertainment and their surgery, with analyses performed for both follow-up periods. Controls were BRCA1/2 mutation carriers with no history of bilateral Prophylactic Mastectomy matched to cases on gene, center, and year of birth. Both cases and controls were excluded for previous or concurrent diagnosis of breast cancer. Analyses were adjusted for duration of endogenous ovarian hormone ...
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Psychosocial functioning in women who have undergone bilateral Prophylactic Mastectomy.
Psycho-oncology, 2004Co-Authors: Kelly A. Metcalfe, Mary Jane Esplen, Vivek Goel, Steven A. NarodAbstract:The purpose of this study was to determine the current psychosocial functioning of women who had previously had a bilateral Prophylactic Mastectomy. Women in the province of Ontario who had undergone Prophylactic Mastectomy between 1991 and 2000 were asked to complete questionnaires that assessed psychological distress, sexual activity, overall satisfaction with decision to have a Prophylactic Mastectomy, and body image. Ninety-seven percent of the women were satisfied with their decision to have a Prophylactic Mastectomy, but young women (
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psychosocial functioning in women who have undergone bilateral Prophylactic Mastectomy
Psycho-oncology, 2004Co-Authors: Kelly A. Metcalfe, Mary Jane Esplen, Vivek Goel, Steven A. NarodAbstract:The purpose of this study was to determine the current psychosocial functioning of women who had previously had a bilateral Prophylactic Mastectomy. Women in the province of Ontario who had undergone Prophylactic Mastectomy between 1991 and 2000 were asked to complete questionnaires that assessed psychological distress, sexual activity, overall satisfaction with decision to have a Prophylactic Mastectomy, and body image. Ninety-seven percent of the women were satisfied with their decision to have a Prophylactic Mastectomy, but young women (<50 years) were less likely to report satisfaction than older women (p=0.001). Women with a strong family history of breast cancer or a BRCA1 or BRCA2 mutation experienced more cancer-related distress than those with a limited family history. Women who had reconstruction following Mastectomy reported higher levels of satisfaction with general body shape and appearance than those without reconstruction. In conclusion, the majority of women were satisfied with their decision to undergo Prophylactic Mastectomy and were not experiencing abnormal levels of psychological distress, low levels of sexual activity, or difficulties with body image. Copyright © 2003 John Wiley & Sons, Ltd.
Kelly A. Metcalfe - One of the best experts on this subject based on the ideXlab platform.
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Predictors of quality of life in women with a bilateral Prophylactic Mastectomy.
Breast Journal, 2020Co-Authors: Kelly A. Metcalfe, Mary Jane Esplen, Vivek Goel, Steven A. NarodAbstract:: The purpose of this study was to assess the quality of life in women who had previously undergone a bilateral Prophylactic Mastectomy and to determine what factors predict quality of life in this population. Women in Ontario who had undergone Prophylactic Mastectomy between 1991 and 2000 were asked to complete several questionnaires that assessed current psychosocial functioning, including the Quality of Life Index (QLI). The mean score for the QLI was 23.34 (range 9.53–30.00). QLI scores were negatively correlated with cancer-related distress, body image difficulties, and psychological distress. Conversely, QLI scores were positively correlated with social support. Significant predictors of quality of life included psychological distress and one subscale of body image (vulnerability). Vulnerability and psychological distress are important predictors of quality of life in women who have previously undergone bilateral Prophylactic Mastectomy.
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international rates of breast reconstruction after Prophylactic Mastectomy in brca1 and brca2 mutation carriers
Annals of Surgical Oncology, 2013Co-Authors: John Semple, Kelly A. Metcalfe, Henry T Lynch, Charmaine Kimsing, Leigha Senter, Peter Ainsworth, Jan Lubinski, Nadine Tung, Donna GilchristAbstract:Background Breast reconstruction is an option for women with BRCA1 or BRCA2 mutations who elect to undergo Prophylactic Mastectomy to prevent breast cancer. We report on the uptake of breast reconstruction after Prophylactic Mastectomy in women with BRCA mutations from eight countries.
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Psychosocial functioning in women who have undergone bilateral Prophylactic Mastectomy.
Psycho-oncology, 2004Co-Authors: Kelly A. Metcalfe, Mary Jane Esplen, Vivek Goel, Steven A. NarodAbstract:The purpose of this study was to determine the current psychosocial functioning of women who had previously had a bilateral Prophylactic Mastectomy. Women in the province of Ontario who had undergone Prophylactic Mastectomy between 1991 and 2000 were asked to complete questionnaires that assessed psychological distress, sexual activity, overall satisfaction with decision to have a Prophylactic Mastectomy, and body image. Ninety-seven percent of the women were satisfied with their decision to have a Prophylactic Mastectomy, but young women (
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psychosocial functioning in women who have undergone bilateral Prophylactic Mastectomy
Psycho-oncology, 2004Co-Authors: Kelly A. Metcalfe, Mary Jane Esplen, Vivek Goel, Steven A. NarodAbstract:The purpose of this study was to determine the current psychosocial functioning of women who had previously had a bilateral Prophylactic Mastectomy. Women in the province of Ontario who had undergone Prophylactic Mastectomy between 1991 and 2000 were asked to complete questionnaires that assessed psychological distress, sexual activity, overall satisfaction with decision to have a Prophylactic Mastectomy, and body image. Ninety-seven percent of the women were satisfied with their decision to have a Prophylactic Mastectomy, but young women (<50 years) were less likely to report satisfaction than older women (p=0.001). Women with a strong family history of breast cancer or a BRCA1 or BRCA2 mutation experienced more cancer-related distress than those with a limited family history. Women who had reconstruction following Mastectomy reported higher levels of satisfaction with general body shape and appearance than those without reconstruction. In conclusion, the majority of women were satisfied with their decision to undergo Prophylactic Mastectomy and were not experiencing abnormal levels of psychological distress, low levels of sexual activity, or difficulties with body image. Copyright © 2003 John Wiley & Sons, Ltd.
