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Charles-henry Cottart - One of the best experts on this subject based on the ideXlab platform.
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nse s100b Protein Blood Level assessment during a long distance trail race
Annales De Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
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NSE & S100B Protein Blood Level assessment during a long-distance trail race.
Annales de Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
Romain Jouffroy - One of the best experts on this subject based on the ideXlab platform.
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nse s100b Protein Blood Level assessment during a long distance trail race
Annales De Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
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NSE & S100B Protein Blood Level assessment during a long-distance trail race.
Annales de Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
Barbara Alves - One of the best experts on this subject based on the ideXlab platform.
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nse s100b Protein Blood Level assessment during a long distance trail race
Annales De Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
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NSE & S100B Protein Blood Level assessment during a long-distance trail race.
Annales de Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
Benoit Mauvieux - One of the best experts on this subject based on the ideXlab platform.
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nse s100b Protein Blood Level assessment during a long distance trail race
Annales De Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
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NSE & S100B Protein Blood Level assessment during a long-distance trail race.
Annales de Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
Luc Mallet - One of the best experts on this subject based on the ideXlab platform.
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nse s100b Protein Blood Level assessment during a long distance trail race
Annales De Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
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NSE & S100B Protein Blood Level assessment during a long-distance trail race.
Annales de Biologie Clinique, 2019Co-Authors: Romain Jouffroy, Barbara Alves, Benoit Mauvieux, Luc Mallet, Jean-louis Beaudeux, Charles-henry CottartAbstract:The acute and chronic consequences of long-distance running on brain function have received little attention. The impact of such a hard-physical burden associated with sleep privation during such events such has never been explored in terms of neuropsychological function and brain damage. METHODS Blood samples were collected from 4 athletes before, during and at the end of one of two races: Grand Raid de la Reunion 2017 (GRR: 165 km, elevation gain: 9529 m, 2 runners) and Trail de la Bourbon 2017 (TB: 111 km, elevation gain: 6433 m, 2 runners). Serum S100B and NSE Levels were measured for each runner before, during and after the race. RESULTS Serum S100B Levels (normal range: < 0.15 μg/L) increased early during the race and remained high up to the end of the race in all 4 runners (range: 0.17-0.59 μg/L). NSE Level (normal range: < 15 μg/L) increased in 3 of the 4 runners (range: 16.8-39.2 μg/L). CONCLUSIONS This preliminary study shows the potential interest of S100B and NSE serum assessment during long-distance races. Further studies are needed to confirm these results and to investigate the origins and significance of this increase in brain injury markers.
