The Experts below are selected from a list of 237 Experts worldwide ranked by ideXlab platform
Joungliang Lan - One of the best experts on this subject based on the ideXlab platform.
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primary sjogren s syndrome with Protein Losing Gastroenteropathy report of two cases
Journal of the Formosan Medical Association, 2002Co-Authors: Tsuyi Hsieh, Joungliang Lan, Deryen ChenAbstract:Protein-Losing Gastroenteropathy is a rare complication in autoimmune diseases, especially in Sjogren's syndrome. We report two cases of primary Sjogren's syndrome, one in a 37-year-old female and another in a 50-year-old female, both of whom presented with peripheral edema. Protein-Losing gastroenteropathies of the stomach and small intestine in the first patient and of the small intestine only in the second patient were demonstrated by abdominal Tc-99m labeled albumin abdominal scintigraphy and pathologic findings. Results of gastrointestinal tract biopsies from both patients showed chronic inflammatory cell infiltrations without lymphangiectasis or vasculitis. The patients were successfully treated with corticosteroids. Results of follow-up Tc-99m labeled albumin scintigraphy were well correlated with clinical improvement and the increase in serum albumin. Sjogren's syndrome should be considered as a cause of Protein-Losing enteropathy. Tc-99m labeled albumin abdominal scintigraphy is helpful in diagnosing the condition, locating the Protein-Losing sites, and monitoring the treatment outcome, especially in cases where Protein loss occurs in the stomach.
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tc 99m albumin scintigraphy to monitor the effect of treatment in Protein Losing Gastroenteropathy
Clinical Nuclear Medicine, 2000Co-Authors: Shyhjen Wang, Shihchuan Tsai, Joungliang LanAbstract:Purpose: Tc-99m albumin scintigraphy is a noninvasive method for detecting Protein-Losing Gastroenteropathy. Methods: Seven patients with Protein-Losing Gastroenteropathy were evaluated with Tc-99m albumin scintigraphy. In addition, Tc-99m albumin scintigraphy was used to monitor the effect of treatment in five of these seven patients. The scintigraphic results were compared with serum albumin levels. Results: All seven patients had positive results in the pretreatment images. Changes in scintigraphic findings in the five treated patients correlated well with changes in serum albumin level. Conclusion: Tc-99m albumin scintigraphy is useful not only for diagnosing Protein-Losing Gastroenteropathy but also for monitoring the effect of treatment.
Makoto Ishikawa - One of the best experts on this subject based on the ideXlab platform.
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Protein Losing Gastroenteropathy detected by technetium 99m labeled human serum albumin
The American Journal of Gastroenterology, 1991Co-Authors: Hiroaki Takeda, Tsuneo Takahashi, Shin Ajitsu, Katsuaki Ukai, Hideki Saitoh, Hitoshi Togashi, Makoto IshikawaAbstract:Gastric and fecal clearance of alpha 1-antitrypsin were measured in three cases of Protein-Losing Gastroenteropathy and in two control cases. Abdominal scintigraphy using 99mTc-labeled human serum albumin was performed in all five subjects. All three cases of Protein-Losing Gastroenteropathy showed 99mTc activity in the gastrointestinal tract. In the patient with hypertrophic gastropathy, the activity was seen initially in the stomach and duodenum. In the patients with intestinal lymphangiectasia, the activities were initially in the small bowel. We conclude that 99mTc scintigraphy was useful, not only in diagnosing Protein-Losing enteropathy, but, also, in detecting the responsible region of the gastrointestinal tract.
Deryen Chen - One of the best experts on this subject based on the ideXlab platform.
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primary sjogren s syndrome with Protein Losing Gastroenteropathy report of two cases
Journal of the Formosan Medical Association, 2002Co-Authors: Tsuyi Hsieh, Joungliang Lan, Deryen ChenAbstract:Protein-Losing Gastroenteropathy is a rare complication in autoimmune diseases, especially in Sjogren's syndrome. We report two cases of primary Sjogren's syndrome, one in a 37-year-old female and another in a 50-year-old female, both of whom presented with peripheral edema. Protein-Losing gastroenteropathies of the stomach and small intestine in the first patient and of the small intestine only in the second patient were demonstrated by abdominal Tc-99m labeled albumin abdominal scintigraphy and pathologic findings. Results of gastrointestinal tract biopsies from both patients showed chronic inflammatory cell infiltrations without lymphangiectasis or vasculitis. The patients were successfully treated with corticosteroids. Results of follow-up Tc-99m labeled albumin scintigraphy were well correlated with clinical improvement and the increase in serum albumin. Sjogren's syndrome should be considered as a cause of Protein-Losing enteropathy. Tc-99m labeled albumin abdominal scintigraphy is helpful in diagnosing the condition, locating the Protein-Losing sites, and monitoring the treatment outcome, especially in cases where Protein loss occurs in the stomach.
Yasuhito Sasaki - One of the best experts on this subject based on the ideXlab platform.
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tc 99m albumin scintigraphy in Protein Losing Gastroenteropathy caused by gastric polyposis
Clinical Nuclear Medicine, 1998Co-Authors: Yusuke Inoue, T Ohtake, Hisao Koga, J Nishikawa, Kohki Yoshikawa, Yasuhito SasakiAbstract:A 58-year-old man with gastric polyposis and hypoalbuminemia underwent abdominal imaging with Tc-99m human serum albumin (HSA). This study indicated Protein-Losing Gastroenteropathy, and Protein loss from gastric polyps was suspected. After total gastrectomy, hypoalbuminemia was improved, and follow-up Tc-99m HSA imaging confirmed remission of the disease.
Hiroaki Takeda - One of the best experts on this subject based on the ideXlab platform.
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significance of rapid turnover Proteins in Protein Losing Gastroenteropathy
Hepato-gastroenterology, 2003Co-Authors: Hiroaki Takeda, Katsuyoshi Ishihama, Tadahisa Fukui, Shoichiro Fujishima, Tomohiko Orii, Yuichi Nakazawa, Hongjin Shu, Sumio KawataAbstract:Background/aims We investigated the significance of rapid turnover Proteins (retinal-binding Protein, pre-albumin and transferrin) in Protein-Losing Gastroenteropathy. Methodology We evaluated the levels of these Proteins in 12 patients with Protein-Losing Gastroenteropathy. Results The Protein-Losing Gastroenteropathy patients showed very low level of total serum Protein of 4.3 +/- 0.7 g/dL, albumin 2.1 +/- 0.4 g/dL, and IgG 682 +/- 232 mg/dL. However, retinal-binding Protein was 4.4 +/- 1.9 mg/dL (normal range; 2.5-8.0 mg/dL), pre-albumin 29.3 +/- 7.9 mg/dL (21-43 mg/dL) and transferrin 226 +/- 62 mg/dL (205-370 mg/dL). The levels of rapid turnover Proteins, particularly retinal-binding Protein and pre-albumin were almost preserved within the normal range, despite hypoProteinemia. Conclusions If there is a patient with severe hypoProteinemia and preserved levels of rapid turnover Proteins, Protein-Losing Gastroenteropathy should be suspected and we get a strong proof to do the following examinations such as a fecal clearance of alpha-1 antitrypsin.
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Protein Losing Gastroenteropathy detected by technetium 99m labeled human serum albumin
The American Journal of Gastroenterology, 1991Co-Authors: Hiroaki Takeda, Tsuneo Takahashi, Shin Ajitsu, Katsuaki Ukai, Hideki Saitoh, Hitoshi Togashi, Makoto IshikawaAbstract:Gastric and fecal clearance of alpha 1-antitrypsin were measured in three cases of Protein-Losing Gastroenteropathy and in two control cases. Abdominal scintigraphy using 99mTc-labeled human serum albumin was performed in all five subjects. All three cases of Protein-Losing Gastroenteropathy showed 99mTc activity in the gastrointestinal tract. In the patient with hypertrophic gastropathy, the activity was seen initially in the stomach and duodenum. In the patients with intestinal lymphangiectasia, the activities were initially in the small bowel. We conclude that 99mTc scintigraphy was useful, not only in diagnosing Protein-Losing enteropathy, but, also, in detecting the responsible region of the gastrointestinal tract.
