The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Meng Shao - One of the best experts on this subject based on the ideXlab platform.
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Guadial A and psiguadials C and D, three unusual meroterpenoids from Psidium guajava.
Organic letters, 2012Co-Authors: Meng Shao, Yu-qing Jian, Xiao-jun Huang, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Qingfa Tang, Xuegang Sun, Xiao-qi ZhangAbstract:The first monoterpene-based meroterpenoid (1) and two novel sesquiterpene-based ones (2 and 3) with unprecedented skeletons were isolated from the leaves of Psidium guajava. Their structures with absolute configuration were elucidated by extensive spectroscopic studies. A plausible biosynthetic pathway for all meroterpenoids from the title plant is also proposed. Compounds 2 and 3 showed significant cytotoxicity toward HepG2 and HepG2/ADM cells.
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psiguadials a and b two novel meroterpenoids with unusual skeletons from the leaves of Psidium guajava
Organic Letters, 2010Co-Authors: Meng Shao, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Xiao-qi Zhang, Zhong Liu, Huihui Cao, Chunlin Fan, Heru Chen, Xinsheng YaoAbstract:Psiguadials A (1) and B (2), two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A (3) and guajadial (4), were isolated from the leaves of Psidium guajava. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction, and quantum chemical CD calculation. Compounds 1, 2, and 4 exhibited potent inhibitory effects on the growth of human hepatoma cells.
Xiao-qi Zhang - One of the best experts on this subject based on the ideXlab platform.
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Guadial A and psiguadials C and D, three unusual meroterpenoids from Psidium guajava.
Organic letters, 2012Co-Authors: Meng Shao, Yu-qing Jian, Xiao-jun Huang, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Qingfa Tang, Xuegang Sun, Xiao-qi ZhangAbstract:The first monoterpene-based meroterpenoid (1) and two novel sesquiterpene-based ones (2 and 3) with unprecedented skeletons were isolated from the leaves of Psidium guajava. Their structures with absolute configuration were elucidated by extensive spectroscopic studies. A plausible biosynthetic pathway for all meroterpenoids from the title plant is also proposed. Compounds 2 and 3 showed significant cytotoxicity toward HepG2 and HepG2/ADM cells.
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psiguadials a and b two novel meroterpenoids with unusual skeletons from the leaves of Psidium guajava
Organic Letters, 2010Co-Authors: Meng Shao, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Xiao-qi Zhang, Zhong Liu, Huihui Cao, Chunlin Fan, Heru Chen, Xinsheng YaoAbstract:Psiguadials A (1) and B (2), two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A (3) and guajadial (4), were isolated from the leaves of Psidium guajava. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction, and quantum chemical CD calculation. Compounds 1, 2, and 4 exhibited potent inhibitory effects on the growth of human hepatoma cells.
Ji-kai Liu - One of the best experts on this subject based on the ideXlab platform.
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guajadials c f four unusual meroterpenoids from Psidium guajava
Natural Products and Bioprospecting, 2013Co-Authors: Yuan Gao, Fei Wang, Ping Hai, Ji-kai LiuAbstract:Abstract Guajadials C-F (1–4), four sesquiterpenoid-based meroterpenoids with unprecedented skeletons were isolated from the leaves of Psidium guajava. Their structures and relative configurations were established by extensive spectroscopic analysis. A possible biosynthetic pathway for 1–4 was also proposed.
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isolation and biomimetic synthesis of guajadial b a novel meroterpenoid from Psidium guajava
Organic Letters, 2012Co-Authors: Yuan Gao, Gang-qiang Wang, Kun Wei, Fei Wang, Ping Hai, Ji-kai LiuAbstract:(±)-Guajadial B (1), an unusual humulene-based meroterpenoid, was isolated as a racemate from the leaves of Psidium guajava, collected from Vietnam. The structure of this novel secondary metabolite was established on the basis of extensive analysis of NMR spectra and confirmed by biomimetic synthesis in a domino three-component coupling reaction.
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guajadial an unusual meroterpenoid from guava leaves Psidium guajava
Organic Letters, 2007Co-Authors: Xiaolong Yang, Kunlung Hsieh, Ji-kai LiuAbstract:Guajadial (1), a novel caryophyllene-based meroterpenoid, was isolated from the Leaves of Psidium guajava (guava). The structure and relative stereochemistry of guajadial (1) were elucidated by extensive spectroscopic analysis. A possible biosynthetic pathway for 1 was proposed.
Xinsheng Yao - One of the best experts on this subject based on the ideXlab platform.
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psiguadials a and b two novel meroterpenoids with unusual skeletons from the leaves of Psidium guajava
Organic Letters, 2010Co-Authors: Meng Shao, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Xiao-qi Zhang, Zhong Liu, Huihui Cao, Chunlin Fan, Heru Chen, Xinsheng YaoAbstract:Psiguadials A (1) and B (2), two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A (3) and guajadial (4), were isolated from the leaves of Psidium guajava. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction, and quantum chemical CD calculation. Compounds 1, 2, and 4 exhibited potent inhibitory effects on the growth of human hepatoma cells.
Ying Wang - One of the best experts on this subject based on the ideXlab platform.
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Guapsidial A and Guadials B and C: Three New Meroterpenoids with Unusual Skeletons from the Leaves of Psidium guajava.
Chemistry (Weinheim an der Bergstrasse Germany), 2015Co-Authors: Yu-qing Jian, Xiao-jun Huang, Dong-mei Zhang, Ren-wang Jiang, Minfeng Chen, Bing-xin Zhao, Ying WangAbstract:A novel sesquiterpene-based Psidium meroterpenoid, possessing an unusual coupling pattern, and two new monoterpene-based meroterpenoids with unprecedented skeletons were isolated from the leaves of Psidium guajava. Their structures and absolute configurations were elucidated by spectroscopic, X-ray diffraction, and computational methods. The plausible biosynthetic pathway of these meroterpenoids as well as their cytotoxicities toward HepG2 and HepG2/ADM cells were also discussed.
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Guadial A and psiguadials C and D, three unusual meroterpenoids from Psidium guajava.
Organic letters, 2012Co-Authors: Meng Shao, Yu-qing Jian, Xiao-jun Huang, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Qingfa Tang, Xuegang Sun, Xiao-qi ZhangAbstract:The first monoterpene-based meroterpenoid (1) and two novel sesquiterpene-based ones (2 and 3) with unprecedented skeletons were isolated from the leaves of Psidium guajava. Their structures with absolute configuration were elucidated by extensive spectroscopic studies. A plausible biosynthetic pathway for all meroterpenoids from the title plant is also proposed. Compounds 2 and 3 showed significant cytotoxicity toward HepG2 and HepG2/ADM cells.
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psiguadials a and b two novel meroterpenoids with unusual skeletons from the leaves of Psidium guajava
Organic Letters, 2010Co-Authors: Meng Shao, Dong-mei Zhang, Ren-wang Jiang, Ying Wang, Xiao-qi Zhang, Zhong Liu, Huihui Cao, Chunlin Fan, Heru Chen, Xinsheng YaoAbstract:Psiguadials A (1) and B (2), two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A (3) and guajadial (4), were isolated from the leaves of Psidium guajava. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction, and quantum chemical CD calculation. Compounds 1, 2, and 4 exhibited potent inhibitory effects on the growth of human hepatoma cells.
