The Experts below are selected from a list of 46671 Experts worldwide ranked by ideXlab platform
Bianca Calabria - One of the best experts on this subject based on the ideXlab platform.
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the relationship between illicit amphetamine use and Psychiatric Symptom profiles in schizophrenia and affective psychoses
Psychiatry Research-neuroimaging, 2018Co-Authors: Alexandra Voce, Rebecca Mcketin, Richard Burns, David Castle, Bianca CalabriaAbstract:Abstract This study examines whether illicit amphetamine use is associated with differences in the prevalence of specific Psychiatric Symptoms in a community sample of individuals diagnosed with schizophrenia or affective psychotic disorders. Data was drawn from the Australian Survey of High Impact Psychosis. The Diagnostic Interview for Psychosis was used to measure substance use and Psychiatric Symptoms. Participants had used amphetamine within their lifetime and had an ICD-10 diagnosis of schizophrenia (n = 347) or an affective psychotic disorder (n = 289). The past year prevalence of Psychiatric Symptoms was compared among those who had used amphetamine in the past year (past-year use, 32%) with those who had not (former use, 68%). Univariate logistic regression analysis indicated that past-year users with schizophrenia had a significantly higher past year prevalence of hallucinations, persecutory delusions, racing thoughts, dysphoria, and anhedonia relative to former amphetamine users with schizophrenia. There were no significant differences in Symptoms between past-year and former users with affective psychotic disorders. The relationship between amphetamine use and specific Psychiatric Symptoms varies across different psychotic disorders. Amphetamine use may hinder prognosis by exacerbating Symptoms of schizophrenia through dopaminergic dysfunctions or depressive vulnerabilities, however, this needs to be confirmed by prospective longitudinal research.
Assaf Oshri - One of the best experts on this subject based on the ideXlab platform.
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Psychiatric Symptom typology in a sample of youth receiving substance abuse treatment services associations with self reported child maltreatment and sexual risk behaviors
Aids and Behavior, 2011Co-Authors: Assaf Oshri, Jonathan G Tubman, James JaccardAbstract:Latent profile analysis (LPA) was used to classify 394 adolescents undergoing substance use treatment, based on past year Psychiatric Symptoms. Relations between profile membership and (a) self-reported childhood maltreatment experiences and (b) current sexual risk behavior were examined. LPA generated three Psychiatric Symptom profiles: Low-, High- Alcohol-, and High- Internalizing Symptoms profiles. Analyses identified significant associations between profile membership and childhood sexual abuse and emotional neglect ratings, as well as co-occurring sex with substance use and unprotected intercourse. Profiles with elevated Psychiatric Symptom scores (e.g., internalizing problems, alcohol abuse and dependence Symptoms) and more severe maltreatment histories reported higher scores for behavioral risk factors for HIV/STI exposure. Heterogeneity in Psychiatric Symptom patterns among youth receiving substance use treatment services, and prior histories of childhood maltreatment, have significant implications for the design and delivery of HIV/STI prevention programs to this population.
Benjamin I Goldstein - One of the best experts on this subject based on the ideXlab platform.
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severe anhedonia among adolescents with bipolar disorder is common and associated with increased Psychiatric Symptom burden
Journal of Psychiatric Research, 2020Co-Authors: Benjamin I Goldstein, Mikaela Dimick, Megan A Hird, Lisa Fiksenbaum, Rachel MitchellAbstract:Abstract Background Anhedonia, a deficit in the ability to experience pleasure, is a cardinal Symptom of major depressive episodes. In contrast to adolescent major depressive disorder, there is limited research examining anhedonia in the context of depression among adolescents with bipolar disorder (BD). We therefore examined clinical characteristics of anhedonia in a large sample of adolescents with BD. Methods Participants were 197 adolescents, aged 13-20 years old, with BD type I, II or not otherwise specified. Diagnoses were determined using a semi-structured interview. Anhedonia severity was rated from one to six on the Depression Rating Scale (DRS). Adolescents were divided into “severe” and “non-severe” anhedonia groups based on the DRS item scoring. The association of anhedonia with clinical and demographic variables was evaluated in univariate analyses followed by logistic regression analyses for variables with p≤0.1. Results Threshold anhedonia was evident among 90.9% during their most severe depressive episode. Significant factors associated with severe most severe lifetime anhedonia (“lifetime anhedonia”) included: female sex, lifetime history of self-injurious behavior, physical abuse, affective lability, higher lifetime depression severity, comorbid anxiety disorders, family history of ADHD, and second-generation antipsychotic use. In regression analyses, severe lifetime anhedonia was independently associated with female sex, comorbid anxiety disorders, most severe lifetime mania severity, and lifetime second generation antipsychotic use. Conclusion The vast majority of adolescents with BD experience anhedonia. More severe anhedonia is associated with indicators of greater illness severity. Future research is warranted to evaluate the neurobiological underpinnings of anhedonia among adolescents with BD.
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longitudinal associations between sleep patterns and Psychiatric Symptom severity in high risk and community comparison youth
Journal of the American Academy of Child and Adolescent Psychiatry, 2019Co-Authors: Adriane M Soehner, Michele A Bertocci, Jessica C Levenson, Tina R Goldstein, Brian Rooks, John Merranko, Danella Hafeman, Rasim Somer Diler, David Axelson, Benjamin I GoldsteinAbstract:Objective Sleep disturbance may be involved in Symptom progression across multiple domains of psychopathology and could represent a target for treatment development in youth. Our objective was to identify sleep patterns that longitudinally change in conjunction with Psychiatric Symptom severity in at-risk youth. Method The study included 484 Pittsburgh Bipolar Offspring Study (BIOS) youth with at least 2 sleep assessments occurring between 10 and 18 years of age: 267 offspring of parents with bipolar I or II disorder and 217 community comparison offspring. Assessments occurred approximately every 2 years (mean number of assessments, 2.8 ± 0.8; mean follow-up duration, 3.8 ± 1.6 years). Offspring had a range of Psychiatric diagnoses at baseline. Multivariate lasso regression was implemented to select offspring-reported sleep patterns associated with changes in five Psychiatric Symptom measures from baseline through last follow-up (mania, depression, mood lability, anxiety, inattention/externalizing). Analyses accounted for parent Psychiatric diagnoses and offspring demographics, Psychiatric diagnoses, and medications. Results Follow-up duration, baseline socioeconomic status, parental history of bipolar disorder, offspring attention-deficit/hyperactivity disorder, and disruptive behavior disorder, and five sleep patterns were identified as predictors of change in all five Psychiatric Symptom measures. Decreasing sleep duration, later sleep timing preference, longer sleep latency, increasing nighttime awakenings, and greater sleepiness over follow-up were associated with increasing severity the five Psychiatric Symptom outcomes over follow-up. These 10 predictors explained 16% of the variance in longitudinal Psychiatric Symptom change, 33% of which was accounted for by sleep predictors. Conclusion A constellation of sleep features were associated with Psychiatric Symptom changes in youth, and may represent viable targets for future interventions.
Sherrilyn M. Sklar - One of the best experts on this subject based on the ideXlab platform.
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Retention in Substance Abuse Treatment: Role of Psychiatric Symptom Severity
The American journal on addictions, 1997Co-Authors: Helen E. Ross, Melissa Cutler, Sherrilyn M. SklarAbstract:The authors investigated the association between Psychiatric Symptom severity and subsequent treatment retention among substance abusers. The Symptom Check List-90–R was administered, after admission to an addiction treatment facility, to 308 male and 106 female clients with moderate-to-severe substance abuse problems. Mean scores on nine Symptom and three summary scales were computed. Controlling for other sociodemographic and treatment variables, somatization was significantly associated with dropout from specialized outpatient and inpatient treatment programs. This study, however: suggests that psychopathologic Symptom severity at admission has only limited utility in Predicting subsequent treatment retention among substance abusers with overall moderate levels of psychological distress.
James Jaccard - One of the best experts on this subject based on the ideXlab platform.
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Psychiatric Symptom typology in a sample of youth receiving substance abuse treatment services associations with self reported child maltreatment and sexual risk behaviors
Aids and Behavior, 2011Co-Authors: Assaf Oshri, Jonathan G Tubman, James JaccardAbstract:Latent profile analysis (LPA) was used to classify 394 adolescents undergoing substance use treatment, based on past year Psychiatric Symptoms. Relations between profile membership and (a) self-reported childhood maltreatment experiences and (b) current sexual risk behavior were examined. LPA generated three Psychiatric Symptom profiles: Low-, High- Alcohol-, and High- Internalizing Symptoms profiles. Analyses identified significant associations between profile membership and childhood sexual abuse and emotional neglect ratings, as well as co-occurring sex with substance use and unprotected intercourse. Profiles with elevated Psychiatric Symptom scores (e.g., internalizing problems, alcohol abuse and dependence Symptoms) and more severe maltreatment histories reported higher scores for behavioral risk factors for HIV/STI exposure. Heterogeneity in Psychiatric Symptom patterns among youth receiving substance use treatment services, and prior histories of childhood maltreatment, have significant implications for the design and delivery of HIV/STI prevention programs to this population.
