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Peter Clive Hayes - One of the best experts on this subject based on the ideXlab platform.

  • Psychological Outcome and quality of life following liver transplantation a prospective national single center study
    Liver Transplantation, 2003
    Co-Authors: Ronan E Ocarroll, Margaret Couston, Jill Cossar, George Masterton, Peter Clive Hayes
    Abstract:

    Liver transplantation is a well-established treatment for liver failure. Prolongation in survival is accepted, but long-term effects of liver transplantation on cognitive and Psychological Outcome are unclear. In the present study, Psychological data were prospectively collected for 164 patients who were assessed for liver transplantation. Memory impairment, psychomotor slowing, anxiety, and depression were commonly observed. Severity of liver disease at assessment was significantly associated with slowing of reaction time. Memory impairment distinguished those who were not listed for transplantation because of illness severity. One year posttransplantation, follow-up data from transplant recipients showed significant improvement in most Psychological domains relative to both healthy comparison participants and patients with chronic liver disease who did not undergo transplantation. Immunosuppression (cyclosporine versus tacrolimus) did not have differential effects on quality of life, fatigue, or affective status, although those administered cyclosporine showed greater improvements at 1-year follow-up on simple and choice reaction times. Elevated levels of anxiety and neuroticism at pretransplantation assessment were associated with worse psychosocial Outcome at 1 year posttransplantation. Severity of liver disease was not related to Psychological Outcome at 1 year. Good Psychological Outcome at 1 year was maintained at the 3-year follow-up. (Liver Transpl 2003;9:712-720.)

Ronan E Ocarroll - One of the best experts on this subject based on the ideXlab platform.

  • Psychological Outcome and quality of life following liver transplantation a prospective national single center study
    Liver Transplantation, 2003
    Co-Authors: Ronan E Ocarroll, Margaret Couston, Jill Cossar, George Masterton, Peter Clive Hayes
    Abstract:

    Liver transplantation is a well-established treatment for liver failure. Prolongation in survival is accepted, but long-term effects of liver transplantation on cognitive and Psychological Outcome are unclear. In the present study, Psychological data were prospectively collected for 164 patients who were assessed for liver transplantation. Memory impairment, psychomotor slowing, anxiety, and depression were commonly observed. Severity of liver disease at assessment was significantly associated with slowing of reaction time. Memory impairment distinguished those who were not listed for transplantation because of illness severity. One year posttransplantation, follow-up data from transplant recipients showed significant improvement in most Psychological domains relative to both healthy comparison participants and patients with chronic liver disease who did not undergo transplantation. Immunosuppression (cyclosporine versus tacrolimus) did not have differential effects on quality of life, fatigue, or affective status, although those administered cyclosporine showed greater improvements at 1-year follow-up on simple and choice reaction times. Elevated levels of anxiety and neuroticism at pretransplantation assessment were associated with worse psychosocial Outcome at 1 year posttransplantation. Severity of liver disease was not related to Psychological Outcome at 1 year. Good Psychological Outcome at 1 year was maintained at the 3-year follow-up. (Liver Transpl 2003;9:712-720.)

Mark Ashworth - One of the best experts on this subject based on the ideXlab platform.

  • measuring Psychological change during cognitive behaviour therapy in primary care a polish study using psychlops Psychological Outcome profiles
    PLOS ONE, 2011
    Co-Authors: Slawomir Czachowski, Peter R. Schofield, Paul T Seed, Mark Ashworth
    Abstract:

    Background: Psychological Outcome measures are evolving into measures that depict progress over time. Interval measurement during therapy has not previously been reported for a patient-generated measure in primary care. We aimed to determine the sensitivity to change throughout therapy, using ‘PSYCHLOPS’ (Psychological Outcome Profiles), and to determine if new problems appearing during therapy diminish overall improvement. Methods: Responses to PSYCHLOPS, pre-, during- and post-therapy were compared. Setting: patients offered brief cognitive behaviour therapy in primary care in Poland. Results: 238 patients completed the pre-therapy questionnaire, 194 (81.5%) the during-therapy questionnaire and 142 the post-therapy questionnaire (59.7%). For those completing all three questionnaires (n=135), improvement in total scores produced an overall Effect Size of 3.1 (2.7 to 3.4). We estimated change using three methods for dealing with missing values. Single and multiple imputation did not significantly change the Effect Size; ‘Last Value Carried Forward’, the most conservative method, produced an overall Effect Size of 2.3 (1.9 to 2.6). New problems during therapy were reported by 81 patients (60.0%): new problem and original problem scores were of similar magnitude and change scores were not significantly different when compared to patients who did not report new problems. Conclusion: A large proportion of Outcome data is lost when Outcome measures depend upon completed end of therapy questionnaires. The use of a during-therapy measure increases data capture. Missing data still produce difficulties in interpreting overall effect sizes for change. We found no evidence that new problems appearing during therapy hampered overall recovery.

  • are problems prevalent and stable in non clinical populations problems and test retest stability of a patient generated measure psychlops Psychological Outcome profiles in a non clinical student sample
    British Journal of Guidance & Counselling, 2010
    Co-Authors: Christopher H Evans, Mark Ashworth, Marilyn Peters
    Abstract:

    ABSTRACT In straightened times counselling must evidence the changes it promotes on reputable measures. Patient-generated measures complement nomothetic measures and may be nearer the ethos of counselling in eliciting individuals' problems. Scores from such measures from non-clinical samples are rarely reported, making their test-retest stability uncertain. We report the prevalence and stability of self-reported problems using PSYCHLOPS (Psychological Outcome Profiles) in a non-clinical student population. PSYCHLOPS is a four-item, self-administered, patient-generated instrument. PSYCHLOPS was completed twice, 7–10 days apart. A wide range of problems was reported and showed satisfactory test-retest stability: Pearson, 0.66; Spearman, 0.68; intra-class correlation coefficient, 0.70. This is reassuring as instability would undermine PSYCHLOPS as a sensitive change measure.

  • measuring Psychological Outcomes after cognitive behaviour therapy in primary care a comparison between a new patient generated measure psychlops Psychological Outcome profiles and hads hospital anxiety and depression scale
    Journal of Mental Health, 2009
    Co-Authors: Mark Ashworth, Christopher H Evans, Sarah Clement
    Abstract:

    Background: Patient-centred Outcome measures are rarely used in primary care mental health settings.Aim: To determine reliability and change sensitivity for a new patient-generated measure, “PSYCHLOPS” (Psychological Outcome Profiles), comparing those parameters with a conventional Outcome measure.Setting: Patients attending clinical psychology services in primary care.Methods: Standardized responses to PSYCHLOPS, pre- and post-therapy, were compared with responses to HADS.Results: 336 patients were recruited; 140 (42%) completed therapy and submitted post-therapy questionnaires. Complete questionnaire data were available for 114 patients (34%). Cohen's Effect Size was 1.61 for PSYCHLOPS and 1.15 for HADS (t = 5.75, p < 0.001). Internal consistency of questionnaire components were 0.75 and 0.67 pre-therapy, respectively. Change scores of both instruments correlated moderately (Pearson's r 0.65; p < 0.001). Completion rates for PSYCHLOPS pre-therapy were: 98.8 %, (problem domain), 91.2%, (function domain),...

Wentao Wang - One of the best experts on this subject based on the ideXlab platform.

P Berman - One of the best experts on this subject based on the ideXlab platform.