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Muin J Khoury - One of the best experts on this subject based on the ideXlab platform.
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genomics and the prevention and control of common chronic diseases emerging priorities for Public Health action
Preventing Chronic Disease, 2005Co-Authors: Muin J Khoury, George A MensahAbstract:The completion of the Human Genome Project in 2003 continues to raise expectations on near-term applications of human genome discoveries in personalized disease prevention, especially in the area of common chronic diseases (1,2). In fact, almost daily we are confronted with stories of scientific discoveries of human genetic variants that are suggested to affect our risks for one or more of the major common chronic diseases. (See Table 1 for an illustrative sample of news stories published online during December 2004 [3].) Yet the immediate significance of most of these discoveries remains elusive. Despite the scientific excitement and the predictions for personalized prevention and drug treatment, the promise of human gene discovery for Health promotion and disease prevention is yet to be fulfilled (4). Table 1 Examples of News Stories on Human Genome Discoveries Relevant to Common Chronic Diseasesa Increasingly, Public Health practitioners from academic, government, and other organizations have taken a proactive leadership role in assessing the relevance of this technology to population Health and to community-based interventions (a new field often referred to as Public Health Genetics, or genomics) (5). This issue of Preventing Chronic Disease contains several articles illustrating various processes developed and applied by schools of Public Health and state Health departments to evaluate the role of genomics and its relevance to the prevention of chronic diseases in the population (6-11). Johnson et al (6) demonstrate the feasibility and success of using family history as a simple genomic tool to inform and motivate high-risk families to make long-term lifestyle behavior changes for preventing a variety of chronic diseases. Annis et al (7) show that existing population-based databases contain valuable genomic information and can serve as a reliable source for chronic disease program recommendations for early detection, prevention, and risk assessment. Irwin et al (8) examine the genomic content of state Comprehensive Cancer Control programs and show that many states have genomic components in their written plans. Importantly, about 67% of programs that included family history in their plans have already begun implementing their stated goals. Harrison et al (9) describe a process for synthesizing genomics information and for sharing knowledge and lessons learned. Novel educational approaches, such as the one presented by Theisen et al (10), and innovative training tools, such as those highlighted by Bodzin et al (11), will be crucial in efforts to provide continuing education for the Public and Health care professionals. A central theme in all of these papers is the importance of family history as a tool for chronic disease prevention and Health promotion.
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from genes to Public Health the applications of genetic technology in disease prevention Genetics working group
American Journal of Public Health, 1996Co-Authors: Muin J KhouryAbstract:OBJECTIVES: With advances in the Human Genome Project, the implications of genetic technology in disease prevention should be assessed. METHODS: The paradigm suggested in The Future of Public Health--assessment, policy development, and assurance--was used to examine the continuum from genetic technology to Public Health practice. RESULTS: First, important Public Health functions are to (1) assess the impact of genes and their interactions with modifiable disease risk factors on the Health status of the population and (2) assess the impact and safety of genetic testing on the population. Second, given the many implications of genetic testing, the Public Health community should participate in policy development related to the timing and use of genetic testing in disease prevention. Third, whenever appropriate, the Public Health community needs to ensure the development of Public Health Genetics programs (e.g. newborn screening) and evaluate the quality and effectiveness of the use of genetic testing in dise...
George A Mensah - One of the best experts on this subject based on the ideXlab platform.
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genomics and the prevention and control of common chronic diseases emerging priorities for Public Health action
Preventing Chronic Disease, 2005Co-Authors: Muin J Khoury, George A MensahAbstract:The completion of the Human Genome Project in 2003 continues to raise expectations on near-term applications of human genome discoveries in personalized disease prevention, especially in the area of common chronic diseases (1,2). In fact, almost daily we are confronted with stories of scientific discoveries of human genetic variants that are suggested to affect our risks for one or more of the major common chronic diseases. (See Table 1 for an illustrative sample of news stories published online during December 2004 [3].) Yet the immediate significance of most of these discoveries remains elusive. Despite the scientific excitement and the predictions for personalized prevention and drug treatment, the promise of human gene discovery for Health promotion and disease prevention is yet to be fulfilled (4). Table 1 Examples of News Stories on Human Genome Discoveries Relevant to Common Chronic Diseasesa Increasingly, Public Health practitioners from academic, government, and other organizations have taken a proactive leadership role in assessing the relevance of this technology to population Health and to community-based interventions (a new field often referred to as Public Health Genetics, or genomics) (5). This issue of Preventing Chronic Disease contains several articles illustrating various processes developed and applied by schools of Public Health and state Health departments to evaluate the role of genomics and its relevance to the prevention of chronic diseases in the population (6-11). Johnson et al (6) demonstrate the feasibility and success of using family history as a simple genomic tool to inform and motivate high-risk families to make long-term lifestyle behavior changes for preventing a variety of chronic diseases. Annis et al (7) show that existing population-based databases contain valuable genomic information and can serve as a reliable source for chronic disease program recommendations for early detection, prevention, and risk assessment. Irwin et al (8) examine the genomic content of state Comprehensive Cancer Control programs and show that many states have genomic components in their written plans. Importantly, about 67% of programs that included family history in their plans have already begun implementing their stated goals. Harrison et al (9) describe a process for synthesizing genomics information and for sharing knowledge and lessons learned. Novel educational approaches, such as the one presented by Theisen et al (10), and innovative training tools, such as those highlighted by Bodzin et al (11), will be crucial in efforts to provide continuing education for the Public and Health care professionals. A central theme in all of these papers is the importance of family history as a tool for chronic disease prevention and Health promotion.
Jacko Anastasia - One of the best experts on this subject based on the ideXlab platform.
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Public Health Genetics: How Are We Preparing the Next Generation of Public Health Professionals?
2021Co-Authors: Jacko AnastasiaAbstract:Background: Since the Human Genome Project's completion in 2003, the need for increased population genetic literacy has grown exponentially. To address this, Public Health professionals must be educated appropriately to serve the Public best. This study examines the current state of Public Health Genetics (PHG) education within existing Master of Public Health (MPH) programs. Methods: 171 MPH Council on Education for Public Health Accreditation (CEPH)-accredited programs across the nation were identified via a preliminary internet search. The APHA American Public Health Association (APHA) Genomics Forum Policy Committee created 14 survey questions to assess the current status of incorporating Genetics/genomics education within MPH programs. Using the Qualtrics survey system through the University of Pittsburgh, a link to the anonymous survey was sent to each director's email address obtained from each program's website. Results: There were 41 survey responses, with 37 finished to completion for a response rate of 21.6% (37/171). 75.7% (28/37) of respondents reported having courses containing Genetics/genomics information in their programs' coursework. Only 12.6% reported such coursework to be required for program completion. Commonly listed barriers to incorporating Genetics/genomics include: limited faculty knowledge and lack of space in existing courses and programs. Conclusions: Survey results revealed incongruous and limited incorporation of Genetics/genomics within the context of graduate-level Public Health education. While most recorded programs report offering PHG coursework, the extent and requirement of such instruction are not considered necessary for program completion, thereby potentially limiting the genetic literacy of the current pool of Public Health professionals
Patricia A Peyser - One of the best experts on this subject based on the ideXlab platform.
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the interface of Genetics and Public Health research and educational challenges
Annual Review of Public Health, 2000Co-Authors: Melissa A Austin, Patricia A PeyserAbstract:▪ Abstract As the target date for the sequencing of the human genome approaches, there is growing recognition that Public Health practice, research, and education will be impacted by new genetic technologies and information and that a multidisciplinary approach is required. Research in the emerging field of Public Health Genetics encompasses a broad range of disciplines and will increasingly involve the interactions among the investigators in these fields. An overview of these areas of research is provided, with illustrative examples. Education in Public Health Genetics needs to address a variety of audiences, including Public Health graduate students and practitioners, students from related disciplines, and Health care professionals. Two new graduate programs at the Universities of Michigan and Washington and training opportunities for Public Health professionals are described. These educational efforts must be ongoing so that the potential of genetic technology and information can be appropriately used ...
Gilbert S Omenn - One of the best experts on this subject based on the ideXlab platform.
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overview of the symposium on Public Health significance of genomics and eco Genetics
Annual Review of Public Health, 2010Co-Authors: Gilbert S OmennAbstract:Genomic and genetic information is rapidly becoming a major element in Public Health research and emerging Public Health practice. This symposium reviews the methods, findings, and significance of genome-wide association studies from epidemiological and statistical points of view. We examine infectious and inflammatory components of gene-environment interaction in the respiratory system. We note the need for nutrient and dietary data and many other kinds of environmental exposure data in population-based genomic studies. Then we explore the sufficiency of a well-informed family history for Public Health and family counseling purposes. Finally, in an era of direct-to-consumer genomic test promotion, we review the evidence on the critical question, will genetic risk profiles motivate individuals and families to choose more Healthful behaviors? This symposium builds on the foundation of the symposium on Public Health Genetics in Volume 21 (2000) of the Annual Review of Public Health.