The Experts below are selected from a list of 15 Experts worldwide ranked by ideXlab platform
Mirjam Nielen - One of the best experts on this subject based on the ideXlab platform.
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Disease burden in four populations of dog and Cat breeds compared to mixed-breed dogs and European shorthair Cats.
Preventive veterinary medicine, 2017Co-Authors: S. F. A. Keijser, Peter A.j. Leegwater, Hille Fieten, Jan Rothuizen, L.e. Meijndert, B.j. Carrière, F.g. Van Steenbeek, Mirjam NielenAbstract:Current public and professional opinion is that many dog breeds suffer from health issues related to inherited diseases or extreme phenotypes. The aim of this historical comparative observational study was to evaluate the breed-related disease burden in three Purebred dog populations (Chihuahua, French bulldog, Labrador retriever) and one Purebred Cat breed (Persian Cats) in the Netherlands by comparison to a control population of mixed-breed dogs and European Shorthair Cats. A qualitative query was performed, consisting of a literature review and collecting the expert opinions of University veterinary specialists, to gather insight into potential diseases of the study population. Next, a referral clinic case control study of the patients referred to specific medical disciplines in the University Clinic was performed. The odds ratio (OR) was calculated to determine the likelihood of a patient referred to a particular medical discipline being a certain breed. Together, the qualitative query and the case control study resulted in a list of potentially relevant diseases limited to five organ systems per breed. These were analysed in data from primary practices. Patient files from ten primary practices over a period of two years were manually extracted and examined. Four-hundred individual patient records per breed as well as 1000 non-breed records were randomly selected from the 10 practices, weighted per practice size. Records were then examined and the presence or absence of certain diseases was identified. To evaluate the disease burden per breed, proportional difference (PD) was estimated, as well as the animal's age at presentation in months. The results of the referral clinic case control study showed an overrepresentation (Odds Ratio>1.5) of the selected breeds in several medical specialties, while median age at presentation was in some cases significantly lower than in the non-breed animals. Results of the practice-based extended cross-sectional study showed that only a few of the selected diseases contribute to the disease burden in these Purebred populations, which was different from the expectations derived from the literature or expert opinion. Additional results included age difference at presentation, which may be interpreted as age of onset, and could indiCate a higher disease burden for the individual animal. Also, only a small percentage of Purebred dogs was registered with the national kennel club. Our final recommendation is that population-based data mining is needed to evaluate country-specific companion animal health and welfare.
S. F. A. Keijser - One of the best experts on this subject based on the ideXlab platform.
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Disease burden in four populations of dog and Cat breeds compared to mixed-breed dogs and European shorthair Cats.
Preventive veterinary medicine, 2017Co-Authors: S. F. A. Keijser, Peter A.j. Leegwater, Hille Fieten, Jan Rothuizen, L.e. Meijndert, B.j. Carrière, F.g. Van Steenbeek, Mirjam NielenAbstract:Current public and professional opinion is that many dog breeds suffer from health issues related to inherited diseases or extreme phenotypes. The aim of this historical comparative observational study was to evaluate the breed-related disease burden in three Purebred dog populations (Chihuahua, French bulldog, Labrador retriever) and one Purebred Cat breed (Persian Cats) in the Netherlands by comparison to a control population of mixed-breed dogs and European Shorthair Cats. A qualitative query was performed, consisting of a literature review and collecting the expert opinions of University veterinary specialists, to gather insight into potential diseases of the study population. Next, a referral clinic case control study of the patients referred to specific medical disciplines in the University Clinic was performed. The odds ratio (OR) was calculated to determine the likelihood of a patient referred to a particular medical discipline being a certain breed. Together, the qualitative query and the case control study resulted in a list of potentially relevant diseases limited to five organ systems per breed. These were analysed in data from primary practices. Patient files from ten primary practices over a period of two years were manually extracted and examined. Four-hundred individual patient records per breed as well as 1000 non-breed records were randomly selected from the 10 practices, weighted per practice size. Records were then examined and the presence or absence of certain diseases was identified. To evaluate the disease burden per breed, proportional difference (PD) was estimated, as well as the animal's age at presentation in months. The results of the referral clinic case control study showed an overrepresentation (Odds Ratio>1.5) of the selected breeds in several medical specialties, while median age at presentation was in some cases significantly lower than in the non-breed animals. Results of the practice-based extended cross-sectional study showed that only a few of the selected diseases contribute to the disease burden in these Purebred populations, which was different from the expectations derived from the literature or expert opinion. Additional results included age difference at presentation, which may be interpreted as age of onset, and could indiCate a higher disease burden for the individual animal. Also, only a small percentage of Purebred dogs was registered with the national kennel club. Our final recommendation is that population-based data mining is needed to evaluate country-specific companion animal health and welfare.
Arikan Sevket - One of the best experts on this subject based on the ideXlab platform.
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Cats blood types: Distribution of blood types in respect of Cats breed and geographical loCation
Ankara Univ Press, 2007Co-Authors: Arikan SevketAbstract:WOS: 000254709600014Cats have three blood types called as A, B and AB. Blood typing has been performed in both non-pedigree and Purebred Cat populations in various parts of the world. There are noticeable geographical variation in distribution of blood types, which is important in clinical practice in preventing neonatal isoerythrolysis (NI) and acute hemolytic transfusion reactions. This reaction associates with severe hemolytic anemia, anaphylactic shock and even death. Severity of reactions associate with titres of naturally occurring alloantibodies, found in Cat plasma, against the heterelogous blood types. Type A is the most common blood group observed in Cats. In contrast, type AB Cats are rare, with a frequency of less than one per cent in most of the non-pedigree and Purebred Cat populations studied worldwide. Present paper reviews current understanding of blood types, role of geographic localization in the distribution of blood types and their importance in feline transfusion medicine
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Cats Blood types: distribution of blood types ın respect of Cats breed and geographical loCation
2007Co-Authors: Arikan SevketAbstract:Kedilerde A, B ve AB olmak üzere üç farklı kan gurubu bulunur. Dünyanın çeşitli coğrafyalarında yaşayan, hem saf hem de saf olmayan birçok kedi popülasyonuna, kan grubu testi uygulanmıştır. Ancak grupların yüzde dağılımında, önemli coğrafik lokalizasyon farklılıklarının olduğu gözlenmiştir. Kan grupları, neonatal izoeritrolizis (Nİ) ve akut hemolitik transfüzyon reaksiyonlarından kaçınmada, klinikte önemli bir yere sahiptir. Uyumsuz kan transfüzyonu akut hemolotik anemi, anafilaktik şok ve hatta ölümle bile sonuçlanabilmektedir. Oluşan reaksiyonun şiddeti, diğer kan grubu antijenine karşı doğal olarak oluşan ve kan plazmasında hazır bulunan alloantikorların titresi ile doğru orantılı olarak artmaktadır. A gurubu kan, kedilerde en sık rastlanan gruptur. Bunun aksine AB grubu kediye ise oldukça nadir rastlanmakta olup, dünya çapında incelenen saf ve saf olmayan kedi popülasyonlarının çoğunda görülme sıklığı yüzde birden bile azdır. Bu derleme makalede kan grubu, kan grubunun yüzde dağılımında coğrafik lokalizasyonun rolü ve grupların transfüzyon uygulamasındaki önemi konusunda gelinen son nokta değerlendirilmektedir.Cats have three blood types called as A, B and AB. Blood typing has been performed in both non-pedigree and Purebred Cat populations in various parts of the world. There are noticeable geographical variation in distribution of blood types, which is important in clinical practice in preventing neonatal isoerythrolysis (NI) and acute hemolytic transfusion reactions. This reaction associates with severe hemolytic anemia, anaphylactic shock and even death. Severity of reactions associate with titres of naturally occurring alloantibodies, found in Cat plasma, against the heterelogous blood types. Type A is the most common blood group observed in Cats. In contrast, type AB Cats are rare, with a frequency of less than one per cent in most of the non-pedigree and Purebred Cat populations studied worldwide. Present paper reviews current understanding of blood types, role of geographic localization in the distribution of blood types and their importance in feline transfusion medicine
Peter A.j. Leegwater - One of the best experts on this subject based on the ideXlab platform.
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Disease burden in four populations of dog and Cat breeds compared to mixed-breed dogs and European shorthair Cats.
Preventive veterinary medicine, 2017Co-Authors: S. F. A. Keijser, Peter A.j. Leegwater, Hille Fieten, Jan Rothuizen, L.e. Meijndert, B.j. Carrière, F.g. Van Steenbeek, Mirjam NielenAbstract:Current public and professional opinion is that many dog breeds suffer from health issues related to inherited diseases or extreme phenotypes. The aim of this historical comparative observational study was to evaluate the breed-related disease burden in three Purebred dog populations (Chihuahua, French bulldog, Labrador retriever) and one Purebred Cat breed (Persian Cats) in the Netherlands by comparison to a control population of mixed-breed dogs and European Shorthair Cats. A qualitative query was performed, consisting of a literature review and collecting the expert opinions of University veterinary specialists, to gather insight into potential diseases of the study population. Next, a referral clinic case control study of the patients referred to specific medical disciplines in the University Clinic was performed. The odds ratio (OR) was calculated to determine the likelihood of a patient referred to a particular medical discipline being a certain breed. Together, the qualitative query and the case control study resulted in a list of potentially relevant diseases limited to five organ systems per breed. These were analysed in data from primary practices. Patient files from ten primary practices over a period of two years were manually extracted and examined. Four-hundred individual patient records per breed as well as 1000 non-breed records were randomly selected from the 10 practices, weighted per practice size. Records were then examined and the presence or absence of certain diseases was identified. To evaluate the disease burden per breed, proportional difference (PD) was estimated, as well as the animal's age at presentation in months. The results of the referral clinic case control study showed an overrepresentation (Odds Ratio>1.5) of the selected breeds in several medical specialties, while median age at presentation was in some cases significantly lower than in the non-breed animals. Results of the practice-based extended cross-sectional study showed that only a few of the selected diseases contribute to the disease burden in these Purebred populations, which was different from the expectations derived from the literature or expert opinion. Additional results included age difference at presentation, which may be interpreted as age of onset, and could indiCate a higher disease burden for the individual animal. Also, only a small percentage of Purebred dogs was registered with the national kennel club. Our final recommendation is that population-based data mining is needed to evaluate country-specific companion animal health and welfare.
Hille Fieten - One of the best experts on this subject based on the ideXlab platform.
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Disease burden in four populations of dog and Cat breeds compared to mixed-breed dogs and European shorthair Cats.
Preventive veterinary medicine, 2017Co-Authors: S. F. A. Keijser, Peter A.j. Leegwater, Hille Fieten, Jan Rothuizen, L.e. Meijndert, B.j. Carrière, F.g. Van Steenbeek, Mirjam NielenAbstract:Current public and professional opinion is that many dog breeds suffer from health issues related to inherited diseases or extreme phenotypes. The aim of this historical comparative observational study was to evaluate the breed-related disease burden in three Purebred dog populations (Chihuahua, French bulldog, Labrador retriever) and one Purebred Cat breed (Persian Cats) in the Netherlands by comparison to a control population of mixed-breed dogs and European Shorthair Cats. A qualitative query was performed, consisting of a literature review and collecting the expert opinions of University veterinary specialists, to gather insight into potential diseases of the study population. Next, a referral clinic case control study of the patients referred to specific medical disciplines in the University Clinic was performed. The odds ratio (OR) was calculated to determine the likelihood of a patient referred to a particular medical discipline being a certain breed. Together, the qualitative query and the case control study resulted in a list of potentially relevant diseases limited to five organ systems per breed. These were analysed in data from primary practices. Patient files from ten primary practices over a period of two years were manually extracted and examined. Four-hundred individual patient records per breed as well as 1000 non-breed records were randomly selected from the 10 practices, weighted per practice size. Records were then examined and the presence or absence of certain diseases was identified. To evaluate the disease burden per breed, proportional difference (PD) was estimated, as well as the animal's age at presentation in months. The results of the referral clinic case control study showed an overrepresentation (Odds Ratio>1.5) of the selected breeds in several medical specialties, while median age at presentation was in some cases significantly lower than in the non-breed animals. Results of the practice-based extended cross-sectional study showed that only a few of the selected diseases contribute to the disease burden in these Purebred populations, which was different from the expectations derived from the literature or expert opinion. Additional results included age difference at presentation, which may be interpreted as age of onset, and could indiCate a higher disease burden for the individual animal. Also, only a small percentage of Purebred dogs was registered with the national kennel club. Our final recommendation is that population-based data mining is needed to evaluate country-specific companion animal health and welfare.
