Pyloric Stenosis

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H A Heij - One of the best experts on this subject based on the ideXlab platform.

William R Brugge - One of the best experts on this subject based on the ideXlab platform.

  • endoscopic therapy of benign Pyloric Stenosis and gastric outlet obstruction
    Current Opinion in Gastroenterology, 2006
    Co-Authors: Tony E Yusuf, William R Brugge
    Abstract:

    Purpose of review To examine the short and long-term success rates of balloon dilation of Pyloric Stenosis. Recent findings Several large studies have demonstrated high rates of success for the relief of symptoms from Pyloric Stenosis using through-the-scope balloons. These dilating balloons readily increase the diameter of the stenotic pylorus on average from 6 to 16 mm. Patients who require more than two dilations are at high risk of endoscopic failure and the need for surgical intervention. Rapid re-Stenosis rates are observed in patients with malignant Pyloric obstruction. Since many patients with benign Pyloric Stenosis have underlying ulcer disease, helicobacter infection is a relatively common finding. Eradication of this infection at the time of balloon dilation will ensure higher long-term success rates. Summary In summary, benign Pyloric Stenosis can be readily treated with endoscopic balloon dilation and should be the first-line therapy.

Matthijs W N Oomen - One of the best experts on this subject based on the ideXlab platform.

Akio Kubota - One of the best experts on this subject based on the ideXlab platform.

  • intravenous atropine treatment in infantile hypertrophic Pyloric Stenosis
    Archives of Disease in Childhood, 2002
    Co-Authors: Hisayoshi Kawahara, Kenji Imura, Masanori Nishikawa, Makoto Yagi, Akio Kubota
    Abstract:

    Aims: To assess the efficacy of a new regimen of intravenous atropine treatment for infantile hypertrophic Pyloric Stenosis (IHPS) with special reference to regression of Pyloric hypertrophy. Methods: Atropine was given intravenously at a dose of 0.01 mg/kg six times a day before feeding in 19 patients with IHPS diagnosed from radiographic and ultrasonographic findings. When vomiting ceased and the infants were able to ingest 150 ml/kg/day formula after stepwise increases in feeding volume, they were given 0.02 mg/kg atropine six times a day orally and the dose was decreased stepwise. Results: Of the 19 infants, 17 (89%) ceased projectile vomiting after treatment with intravenous (median seven days) and subsequent oral (median 44 days) atropine administration. The remaining two infants required surgery. No significant complications were encountered. Ultrasonography showed a significant (p < 0.05) decrease in Pyloric muscle thickness, but no significant shortening of the Pyloric canal after completion of the atropine treatment. The patients exhibited failure to thrive at presentation, but were thriving at 6 months of age (p < 0.01). Conclusions: This atropine therapy resulted in satisfactory clinical recovery. Pyloric muscle thickness was significantly reduced.

S Sydney C Chung - One of the best experts on this subject based on the ideXlab platform.

  • laparoscopic truncal vagotomy and gastroenterostomy for Pyloric Stenosis
    American Journal of Surgery, 1996
    Co-Authors: Andrew Wyman, Robert C Stuart, S Sydney C Chung
    Abstract:

    Background Gastric outlet obstruction secondary to chronic duodenal ulceration is an indication for surgery as conservative management with balloon dilatation frequently fails. The standard operation is truncal vagotomy and a drainage procedure. However, development of minimally invasive surgery has revolutionized the surgical approach to this clinical problem. Methods Twelve male patients with Pyloric Stenosis secondary to duodenal ulceration underwent laparoscopic truncal vagotomy and gastrojejunostomy. The perioperative and long term outcome of this group of patients were analyzed. Results The median operating time was 210 (range 180 to 240) minutes. Median postoperative stay was 6 (range 4 to 41) days. Conversion to laparotomy was necessary in one patient. Delayed gastric emptying occurred in two patients but resolved on conservative measures. At a median postoperative followup of 6 (range 1 to 12) months all patients had a good symptomatic outcome (Visick grades I or II). Conclusions Laparoscopic truncal vagotomy and gastrojejunostomy is a feasible technique. Intermediate followup shows good symptomatic results when used for Pyloric Stenosis.