The Experts below are selected from a list of 138 Experts worldwide ranked by ideXlab platform
Alakesh Bisai - One of the best experts on this subject based on the ideXlab platform.
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unified approach to the spiro pyrrolidinyl oxindole and hexahydropyrrolo 2 3 b indole alkaloids total syntheses of pseudophrynamines 270 and 272a
Organic Letters, 2015Co-Authors: Mrinal Kanti Das, Subhajit Bhunia, Alakesh BisaiAbstract:The first enantioselective total syntheses of architecturally interesting prenylated Pyrroloindole alkaloids, (−)-pseudophrynamines 272A (3d) and 270 (3b), have been achieved starting from enantioenriched 2-oxindoles having all-carbon quaternary stereocenters. A common strategy involving a thio-urea catalyzed aldol reaction is employed for the total synthesis of both spiro(pyrrolidinyl-oxindole) and hexahydropyrrolo[2,3-b]indole alkaloids.
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Unified Approach to the Spiro(pyrrolidinyl-oxindole) and Hexahydropyrrolo[2,3‑b]indole Alkaloids: Total Syntheses of Pseudophrynamines 270 and 272A
2015Co-Authors: Mrinal Kanti Das, Subhajit Bhunia, Alakesh BisaiAbstract:The first enantioselective total syntheses of architecturally interesting prenylated Pyrroloindole alkaloids, (−)-pseudophrynamines 272A (3d) and 270 (3b), have been achieved starting from enantioenriched 2-oxindoles having all-carbon quaternary stereocenters. A common strategy involving a thio-urea catalyzed aldol reaction is employed for the total synthesis of both spiro(pyrrolidinyl-oxindole) and hexahydropyrrolo[2,3-b]indole alkaloids
Raghavachary Raghunathan - One of the best experts on this subject based on the ideXlab platform.
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solid supported microwave accelerated intramolecular knoevenagel hetero diels alder reactions a protocol for the synthesis of indolo 2 1 a pyrrolo 4 3 4 5 pyran ring systems
Synlett, 2007Co-Authors: Rathna Durga R S Manian, Jayadevan Jayashankaran, Raghavachary RaghunathanAbstract:A novel and mild method was established to synthesize Pyrroloindole derivatives. This method entails an ethylenediammonium diacetate (EDDA)-promoted Knoevenagel condensation of various diones with appropriately substituted aldehydes to yield the arylidene intermediate, which was smoothly converted to the final products by intramolecular Diels-Alder reaction in a tandem manner. This process describes a practical synthetic method to prepare Pyrroloindole derivatives.
Mrinal Kanti Das - One of the best experts on this subject based on the ideXlab platform.
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unified approach to the spiro pyrrolidinyl oxindole and hexahydropyrrolo 2 3 b indole alkaloids total syntheses of pseudophrynamines 270 and 272a
Organic Letters, 2015Co-Authors: Mrinal Kanti Das, Subhajit Bhunia, Alakesh BisaiAbstract:The first enantioselective total syntheses of architecturally interesting prenylated Pyrroloindole alkaloids, (−)-pseudophrynamines 272A (3d) and 270 (3b), have been achieved starting from enantioenriched 2-oxindoles having all-carbon quaternary stereocenters. A common strategy involving a thio-urea catalyzed aldol reaction is employed for the total synthesis of both spiro(pyrrolidinyl-oxindole) and hexahydropyrrolo[2,3-b]indole alkaloids.
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Unified Approach to the Spiro(pyrrolidinyl-oxindole) and Hexahydropyrrolo[2,3‑b]indole Alkaloids: Total Syntheses of Pseudophrynamines 270 and 272A
2015Co-Authors: Mrinal Kanti Das, Subhajit Bhunia, Alakesh BisaiAbstract:The first enantioselective total syntheses of architecturally interesting prenylated Pyrroloindole alkaloids, (−)-pseudophrynamines 272A (3d) and 270 (3b), have been achieved starting from enantioenriched 2-oxindoles having all-carbon quaternary stereocenters. A common strategy involving a thio-urea catalyzed aldol reaction is employed for the total synthesis of both spiro(pyrrolidinyl-oxindole) and hexahydropyrrolo[2,3-b]indole alkaloids
Rajagopal Nagarajan - One of the best experts on this subject based on the ideXlab platform.
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An efficient, one-pot synthesis of isomeric ellipticine derivatives through intramolecular imino-diels-alder reaction
Organic Letters, 2008Co-Authors: Vikram Gaddam, Rajagopal NagarajanAbstract:New analogues of isomeric ellipticine derivatives fused with biologically important Pyrroloindole or chromene moiety have been synthesized by utilizing an intramolecular imino Diels-Alder reaction in a single step.
Rathna Durga R S Manian - One of the best experts on this subject based on the ideXlab platform.
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solid supported microwave accelerated intramolecular knoevenagel hetero diels alder reactions a protocol for the synthesis of indolo 2 1 a pyrrolo 4 3 4 5 pyran ring systems
Synlett, 2007Co-Authors: Rathna Durga R S Manian, Jayadevan Jayashankaran, Raghavachary RaghunathanAbstract:A novel and mild method was established to synthesize Pyrroloindole derivatives. This method entails an ethylenediammonium diacetate (EDDA)-promoted Knoevenagel condensation of various diones with appropriately substituted aldehydes to yield the arylidene intermediate, which was smoothly converted to the final products by intramolecular Diels-Alder reaction in a tandem manner. This process describes a practical synthetic method to prepare Pyrroloindole derivatives.
