The Experts below are selected from a list of 219 Experts worldwide ranked by ideXlab platform
Pasi Paavilainen - One of the best experts on this subject based on the ideXlab platform.
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Vascularized second metatarsophalangeal joint transfer for Radial deficiency - an update.
The Journal of hand surgery European volume, 2018Co-Authors: Simo K. Vilkki, Pasi PaavilainenAbstract:Vascularized second metatarsophalangeal joint transfer offers a possibility to reconstruct the Radial Support which is lacking in Radial dysplasia. Our experience from 1987 to 2017 with 34 congenital Radial club hand reconstructions have allowed a possibility for long-term evaluation of the method. Compared with conventional methods, second metatarsophalangeal joint transfer results in better wrist mobility and does not restrict typical ulnar growth. The balance of the wrist remains good until age 11. Thereafter, the growth of the vascularized bone graft transfer matches only partially the distal ulnar growth in adolescence, resulting in mild recurrence of Radial deviation. A new option to create a two-bone forearm in selected Bayne-Klug Type III Radial dysplasia cases will allow a relatively good pro-supination ability. Potentially, a proximal fibular epiphyseal transfer could be a future solution. Currently, a safe harvest of the proximal fibula at childhood remains controversial.
Christian W. Hamm - One of the best experts on this subject based on the ideXlab platform.
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A new novolimus-eluting bioresorbable coronary scaffold: Present status and future clinical perspectives
International journal of cardiology, 2016Co-Authors: Holger Nef, Jens Wiebe, Nicolas Foin, Florian Blachutzik, Oliver Dörr, Sara Toyloy, Christian W. HammAbstract:Abstract The DESolve® scaffold (Elixir Medical Corporation, Sunnyvale, California, USA) is manufactured from a poly-l-lactide based polymer and elutes an anti-proliferative, anti-inflammatory drug, Novolimus from a poly-l-lactide based topcoat mixture. The strut thickness is 150μm and the scaffold has platinum–iridium radiopaque markers at both ends. Radial Support is available during the early time period to prevent recoil. The scaffold biodegrades within 1year (>90% reduction in molecular weight) and then completely bioresorbs within 2years. The DESolve® scaffold permits a wide range of expansion with a consequently reduced risk for strut fracture. Lumen and scaffold enlargement is observed within 3–6months in both preclinical and clinical studies potentially allowing for the scaffolded region to respond to vasoactive stimuli. The device has a unique property of self-correction observed in bench top studies, which in clinical practice has the potential to eliminate minor malapposition following deployment.
Simo K. Vilkki - One of the best experts on this subject based on the ideXlab platform.
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Vascularized second metatarsophalangeal joint transfer for Radial deficiency - an update.
The Journal of hand surgery European volume, 2018Co-Authors: Simo K. Vilkki, Pasi PaavilainenAbstract:Vascularized second metatarsophalangeal joint transfer offers a possibility to reconstruct the Radial Support which is lacking in Radial dysplasia. Our experience from 1987 to 2017 with 34 congenital Radial club hand reconstructions have allowed a possibility for long-term evaluation of the method. Compared with conventional methods, second metatarsophalangeal joint transfer results in better wrist mobility and does not restrict typical ulnar growth. The balance of the wrist remains good until age 11. Thereafter, the growth of the vascularized bone graft transfer matches only partially the distal ulnar growth in adolescence, resulting in mild recurrence of Radial deviation. A new option to create a two-bone forearm in selected Bayne-Klug Type III Radial dysplasia cases will allow a relatively good pro-supination ability. Potentially, a proximal fibular epiphyseal transfer could be a future solution. Currently, a safe harvest of the proximal fibula at childhood remains controversial.
Ron Waksman - One of the best experts on this subject based on the ideXlab platform.
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The Effects of Novel, Bioresorbable Scaffolds on Coronary Vascular Pathophysiology
Journal of Cardiovascular Translational Research, 2014Co-Authors: Michael J. Lipinski, Ricardo O. Escarcega, Thibault Lhermusier, Ron WaksmanAbstract:Percutaneous coronary intervention (PCI) has rapidly evolved over the past 30 years as technology has sought to improve clinical outcomes by addressing pathophysiologic complications arising from the intervention. Stents were designed to resolve the drawbacks of balloon angioplasty by providing Radial Support to prevent vessel recoil, by sealing coronary dissections, and by preventing abrupt vessel closure. The conceptualization of an ideal drug-eluting fully bioresorbable scaffold (BRS), whether metallic or polymeric, would theoretically address the adverse aspects of permanent metallic stents. In this review of the literature, we will discuss the impact these novel fully BRS platforms have on vascular pathophysiology following PCI.
Antonio Colombo - One of the best experts on this subject based on the ideXlab platform.
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Implantation of the peripheral Wallstent for diffuse lesions in coronary arteries and vein grafts.
Catheterization and cardiovascular diagnosis, 1996Co-Authors: Akira Itoh, Patrick Hall, Luigi Maiello, Simonetta Blengino, Massimo Ferraro, Giovanni Martini, Leo Finci, Antonio ColomboAbstract:The Wallstent (Schneider, Bulach, Switzerland) is available in different lengths without much compromise in flexibility and Radial Support compared to some other stents. We treated 24 patients (26 vessels) with diffuse coronary lesions or vein graft lesions with intravascular ultrasound-guided peripheral Wallstent implantation. Average balloon pressure during stent optimization was 16.4 ± 2.7 atm. The stents could be successfully implanted in 24 vessels. Minimal lumen diameter and percent diameter stenosis after stenting were 3.60 ± 0.62 mm and −8 ± 13%, respectively. Average stent length was 63.7 ± 22.7 mm. There was one procedure-related complication. After stenting, all patients were treated only with antiplatelet agents. During 1-month follow-up, there was one subacute stent thrombosis due to incomplete coverage of a distal dissection. These preliminary results show the feasibility of this novel approach in selected lesions. © 1996 Wiley-Liss, Inc.
