The Experts below are selected from a list of 29154 Experts worldwide ranked by ideXlab platform
D A Bradley - One of the best experts on this subject based on the ideXlab platform.
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evaluation of ge doped silica fibre tlds for in vivo dosimetry during intraoperative radiotherapy
Physics in Medicine and Biology, 2019Co-Authors: F Moradi, Ghafour Amouzad Mahdiraji, Nur Aishah Taib, Mayeen Uddin Khandaker, D A BradleyAbstract:: Ge-doped silica fibre (GDSF) thermoluminescence dosimeters (TLD) are non-hygroscopic spatially high-resolution Radiation sensors with demonstrated potential for radiotherapy dosimetry applications. The INTRABEAM® system with spherical applicators, one of a number of recent electronic brachytherapy sources designed for intraoperative radiotherapy (IORT), presents a representative challenging dosimetry situation, with a low keV photon beam and a desired rapid dose-rate fall-off close-up to the applicator surface. In this study, using the INTRABEAM® system, investigations were made into the potential application of GDSF TLDs for in vivo IORT dosimetry. The GDSFs were calibrated over the respective dose- and depth-range 1 to 20 Gy and 3 to 45 mm from the x-ray probe. The effect of different sizes of spherical applicator on TL response of the fibres was also investigated. The results show the GDSF TLDs to be applicable for IORT dose assessment, with the important incorporated correction for beam quality effects using different spherical applicator sizes. The total uncertainty in use of this type of GDSF for dosimetry has been found to range between 9.5% to 12.4%. Subsequent in vivo measurement of skin dose for three breast patients undergoing IORT were performed, the measured doses being below the tolerance level for acute Radiation Toxicity.
P Windsor Md Frcr M Ffsem - One of the best experts on this subject based on the ideXlab platform.
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the effect of aerobic exercise on treatment related acute Toxicity in men receiving radical external beam radiotherapy for localised prostate cancer
European Journal of Cancer Care, 2010Co-Authors: Kapur G Frcr, P Windsor Md Frcr M FfsemAbstract:KAPUR G., WINDSOR P.M. & Mc COWAN C. (2010) European Journal of Cancer Care19, 643–647 The effect of aerobic exercise on treatment-related acute Toxicity in men receiving radical external beam radiotherapy for localised prostate cancer We retrospectively analysed acute Radiation Toxicity data for patients who had participated in a randomised controlled study in our centre in order to assess the impact of aerobic exercise on acute rectal and bladder morbidity during treatment. Data from 65 of 66 patients were analysed: 33 allocated into a control group (standard advice) and 33 into an exercise group (aerobic walking for 30 min at least three times per week) during 4 weeks of external beam radiotherapy; one patient in the exercise group withdrew after randomisation before starting radiotherapy. There was a trend towards less severe acute rectal Toxicity in the exercise group with a statistically significant difference in mean Toxicity scores over the 4 weeks of radiotherapy (P = 0.004), with no significant difference in bladder Toxicity scores between the two groups (P = 0.123). The lack of an association for severity of bladder Toxicity could be attributed to the confounding effect of lower urinary tract symptoms from their prostate cancer. Keeping active and being asked to adhere to a well-defined exercise schedule appears to reduce the severity of rectal Toxicity during radiotherapy to the prostate.
Ghafour Amouzad Mahdiraji - One of the best experts on this subject based on the ideXlab platform.
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evaluation of ge doped silica fibre tlds for in vivo dosimetry during intraoperative radiotherapy
Physics in Medicine and Biology, 2019Co-Authors: F Moradi, Ghafour Amouzad Mahdiraji, Nur Aishah Taib, Mayeen Uddin Khandaker, D A BradleyAbstract:: Ge-doped silica fibre (GDSF) thermoluminescence dosimeters (TLD) are non-hygroscopic spatially high-resolution Radiation sensors with demonstrated potential for radiotherapy dosimetry applications. The INTRABEAM® system with spherical applicators, one of a number of recent electronic brachytherapy sources designed for intraoperative radiotherapy (IORT), presents a representative challenging dosimetry situation, with a low keV photon beam and a desired rapid dose-rate fall-off close-up to the applicator surface. In this study, using the INTRABEAM® system, investigations were made into the potential application of GDSF TLDs for in vivo IORT dosimetry. The GDSFs were calibrated over the respective dose- and depth-range 1 to 20 Gy and 3 to 45 mm from the x-ray probe. The effect of different sizes of spherical applicator on TL response of the fibres was also investigated. The results show the GDSF TLDs to be applicable for IORT dose assessment, with the important incorporated correction for beam quality effects using different spherical applicator sizes. The total uncertainty in use of this type of GDSF for dosimetry has been found to range between 9.5% to 12.4%. Subsequent in vivo measurement of skin dose for three breast patients undergoing IORT were performed, the measured doses being below the tolerance level for acute Radiation Toxicity.
Mayeen Uddin Khandaker - One of the best experts on this subject based on the ideXlab platform.
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evaluation of ge doped silica fibre tlds for in vivo dosimetry during intraoperative radiotherapy
Physics in Medicine and Biology, 2019Co-Authors: F Moradi, Ghafour Amouzad Mahdiraji, Nur Aishah Taib, Mayeen Uddin Khandaker, D A BradleyAbstract:: Ge-doped silica fibre (GDSF) thermoluminescence dosimeters (TLD) are non-hygroscopic spatially high-resolution Radiation sensors with demonstrated potential for radiotherapy dosimetry applications. The INTRABEAM® system with spherical applicators, one of a number of recent electronic brachytherapy sources designed for intraoperative radiotherapy (IORT), presents a representative challenging dosimetry situation, with a low keV photon beam and a desired rapid dose-rate fall-off close-up to the applicator surface. In this study, using the INTRABEAM® system, investigations were made into the potential application of GDSF TLDs for in vivo IORT dosimetry. The GDSFs were calibrated over the respective dose- and depth-range 1 to 20 Gy and 3 to 45 mm from the x-ray probe. The effect of different sizes of spherical applicator on TL response of the fibres was also investigated. The results show the GDSF TLDs to be applicable for IORT dose assessment, with the important incorporated correction for beam quality effects using different spherical applicator sizes. The total uncertainty in use of this type of GDSF for dosimetry has been found to range between 9.5% to 12.4%. Subsequent in vivo measurement of skin dose for three breast patients undergoing IORT were performed, the measured doses being below the tolerance level for acute Radiation Toxicity.
Colin Mccowan - One of the best experts on this subject based on the ideXlab platform.
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the effect of aerobic exercise on treatment related acute Toxicity in men receiving radical external beam radiotherapy for localised prostate cancer
European Journal of Cancer Care, 2010Co-Authors: G Kapur, P M Windsor, Colin MccowanAbstract:We retrospectively analysed acute Radiation Toxicity data for patients who had participated in a randomised controlled study in our centre in order to assess the impact of aerobic exercise on acute rectal and bladder morbidity during treatment. Data from 65 of 66 patients were analysed: 33 allocated into a control group (standard advice) and 33 into an exercise group (aerobic walking for 30 min at least three times per week) during 4 weeks of external beam radiotherapy; one patient in the exercise group withdrew after randomisation before starting radiotherapy. There was a trend towards less severe acute rectal Toxicity in the exercise group with a statistically significant difference in mean Toxicity scores over the 4 weeks of radiotherapy (P=0.004), with no significant difference in bladder Toxicity scores between the two groups (P=0.123). The lack of an association for severity of bladder Toxicity could be attributed to the confounding effect of lower urinary tract symptoms from their prostate cancer. Keeping active and being asked to adhere to a well-defined exercise schedule appears to reduce the severity of rectal Toxicity during radiotherapy to the prostate.
