The Experts below are selected from a list of 1293 Experts worldwide ranked by ideXlab platform
Kam-fai Wong - One of the best experts on this subject based on the ideXlab platform.
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC pulmonary medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS).
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC Pulmonary Medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS). Methods In a prospective, randomized, controlled study, all patients who underwent FB with propofol Sedation were monitored and their Sedation adjusted. During FB, one group was monitored by AEP and another group was monitored by RSS. The propofol dosage was adjusted by the nursing staff during examination to maintain the Alaris AEP index (AAI) value between 25 and 40 in the AEP group and the RSS at 5 or 6 in the RSS group. Before FB and during FB, the AAI, heart rate (HR), and mean arterial pressure (MAP) were recorded every 5 min. The percentages of time at the Sedation target and the propofol dosages were calculated. Results Nineteen patients received AEP monitoring and 18 patients received RSS monitoring. The percentage of time at the Sedation target during FB was significantly higher in the AEP monitoring group (51.3%; interquartile range [IQR], 47.0–63.5%) than in the RSS group (15.4%; IQR, 9.5–23.4%), ( P < 0.001). During FB, the RSS group had a significantly higher AAI ( P = 0.011), HR ( P < 0.001), and MAP ( P < 0.001) than the AEP group. Conclusions In mechanically ventilated patients undergoing FB, AEP monitoring resulted in less variation in AAI, HR, and MAP, and a higher percentage of time at the Sedation target than RSS monitoring. Trial registration ClinicalTrials.gov NCT01448811 .
Chien-wei Hsu - One of the best experts on this subject based on the ideXlab platform.
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC pulmonary medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS).
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC Pulmonary Medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS). Methods In a prospective, randomized, controlled study, all patients who underwent FB with propofol Sedation were monitored and their Sedation adjusted. During FB, one group was monitored by AEP and another group was monitored by RSS. The propofol dosage was adjusted by the nursing staff during examination to maintain the Alaris AEP index (AAI) value between 25 and 40 in the AEP group and the RSS at 5 or 6 in the RSS group. Before FB and during FB, the AAI, heart rate (HR), and mean arterial pressure (MAP) were recorded every 5 min. The percentages of time at the Sedation target and the propofol dosages were calculated. Results Nineteen patients received AEP monitoring and 18 patients received RSS monitoring. The percentage of time at the Sedation target during FB was significantly higher in the AEP monitoring group (51.3%; interquartile range [IQR], 47.0–63.5%) than in the RSS group (15.4%; IQR, 9.5–23.4%), ( P < 0.001). During FB, the RSS group had a significantly higher AAI ( P = 0.011), HR ( P < 0.001), and MAP ( P < 0.001) than the AEP group. Conclusions In mechanically ventilated patients undergoing FB, AEP monitoring resulted in less variation in AAI, HR, and MAP, and a higher percentage of time at the Sedation target than RSS monitoring. Trial registration ClinicalTrials.gov NCT01448811 .
Jin Woo Lee - One of the best experts on this subject based on the ideXlab platform.
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Dexmedetomidine versus midazolam for Sedation during endobronchial ultrasound-guided transbronchial needle aspiration: A randomised controlled trial.
European journal of anaesthesiology, 2020Co-Authors: Junghyun Kim, Sun Mi Choi, Young Sik Park, Changhoon Lee, Sangmin Lee, Chul-gyu Yoo, Young Whan Kim, Jin Woo LeeAbstract:BACKGROUND Desaturation is a common complication of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Dexmedetomidine (DEX), a commonly used sedative in intensive care, is associated with less respiratory depression compared with other sedatives. OBJECTIVE We compared DEX with midazolam (MDZ) when used as a sedative during EBUS-TBNA. DESIGN A randomised, parallel, double-blinded trial. SETTING A university-affiliated teaching hospital between June 2014 and July 2015 PATIENTS: A total of 102 patients who underwent EBUS-TBNA were randomly allocated to two groups (48 DEX group, 54 MDZ group). INTERVENTIONS DEX group received 0.25 to 0.75 μg kg h (start with 0.5 μg kg h, modulated in three steps from 0.25 to 0.75 μg kg h) of DEX after a loading dose of 0.25 μg kg h for 10 min to maintain a Ramsay Sedation Scale (RSS) of 3to 5. If the patient was agitated, 1 mg of MDZ bolus was used as a rescue drug. Patients in the MDZ group initially received 0.05 mg kg of MDZ as a bolus. For maintenance and rescue, 1 mg of MDZ bolus was used. MAIN OUTCOME MEASURES The primary outcome was the presence of oxygen desaturation. Secondary outcomes were level of Sedation (Ramsay Sedation Scale score), cough score, Sedation and procedure satisfaction score. RESULTS The baseline characteristics of the patients, duration of EBUS-TBNA procedures and the use of rescue MDZ were not different between the groups. There was no significant difference in desaturation events between the DEX and MDZ groups (56.3 and 68.5%, respectively; P = 0.20). The level of Sedation and the Sedation satisfaction scores were similar between the two groups. However, cough score was significantly lower in the DEX group (41.9 vs. 53.4; P = 0.02). CONCLUSION The use of DEX during EBUS-TBNA was not superior to MDZ in terms of oxygen desaturation. TRIAL REGISTRATION Clinicaltrials.gov identifier: NCT02157818.
Shu-fen Sun - One of the best experts on this subject based on the ideXlab platform.
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC pulmonary medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS).
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC Pulmonary Medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS). Methods In a prospective, randomized, controlled study, all patients who underwent FB with propofol Sedation were monitored and their Sedation adjusted. During FB, one group was monitored by AEP and another group was monitored by RSS. The propofol dosage was adjusted by the nursing staff during examination to maintain the Alaris AEP index (AAI) value between 25 and 40 in the AEP group and the RSS at 5 or 6 in the RSS group. Before FB and during FB, the AAI, heart rate (HR), and mean arterial pressure (MAP) were recorded every 5 min. The percentages of time at the Sedation target and the propofol dosages were calculated. Results Nineteen patients received AEP monitoring and 18 patients received RSS monitoring. The percentage of time at the Sedation target during FB was significantly higher in the AEP monitoring group (51.3%; interquartile range [IQR], 47.0–63.5%) than in the RSS group (15.4%; IQR, 9.5–23.4%), ( P < 0.001). During FB, the RSS group had a significantly higher AAI ( P = 0.011), HR ( P < 0.001), and MAP ( P < 0.001) than the AEP group. Conclusions In mechanically ventilated patients undergoing FB, AEP monitoring resulted in less variation in AAI, HR, and MAP, and a higher percentage of time at the Sedation target than RSS monitoring. Trial registration ClinicalTrials.gov NCT01448811 .
David Lin Lee - One of the best experts on this subject based on the ideXlab platform.
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC pulmonary medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS).
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Monitoring Sedation for bronchoscopy in mechanically ventilated patients by using the Ramsay Sedation Scale versus auditory-evoked potentials
BMC Pulmonary Medicine, 2014Co-Authors: Chien-wei Hsu, Shu-fen Sun, Kuo-an Chu, David Lin Lee, Kam-fai WongAbstract:Background Appropriate Sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the Sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitored by auditory-evoked potentials (AEPs) or the Ramsay Sedation Scale (RSS). Methods In a prospective, randomized, controlled study, all patients who underwent FB with propofol Sedation were monitored and their Sedation adjusted. During FB, one group was monitored by AEP and another group was monitored by RSS. The propofol dosage was adjusted by the nursing staff during examination to maintain the Alaris AEP index (AAI) value between 25 and 40 in the AEP group and the RSS at 5 or 6 in the RSS group. Before FB and during FB, the AAI, heart rate (HR), and mean arterial pressure (MAP) were recorded every 5 min. The percentages of time at the Sedation target and the propofol dosages were calculated. Results Nineteen patients received AEP monitoring and 18 patients received RSS monitoring. The percentage of time at the Sedation target during FB was significantly higher in the AEP monitoring group (51.3%; interquartile range [IQR], 47.0–63.5%) than in the RSS group (15.4%; IQR, 9.5–23.4%), ( P < 0.001). During FB, the RSS group had a significantly higher AAI ( P = 0.011), HR ( P < 0.001), and MAP ( P < 0.001) than the AEP group. Conclusions In mechanically ventilated patients undergoing FB, AEP monitoring resulted in less variation in AAI, HR, and MAP, and a higher percentage of time at the Sedation target than RSS monitoring. Trial registration ClinicalTrials.gov NCT01448811 .
