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Spivak Nia - One of the best experts on this subject based on the ideXlab platform.

  • production of purified human Recombinant Alpha2b Interferon
    2012
    Co-Authors: A I Melnik, N M Zholobak, Spivak Nia
    Abstract:

    Technology for producing biologically active Recombinant Alpha2b-Interferon is based on creating a bacterial producer strain containing the cDNA of human Interferon alpha. The authors have obtained two producers of Recombinant Alpha2b-Interferon, the synthesis of the target protein in them occurs in the inclusion bodies. The schemes of isolation and purification of biologically active Recombinant Alpha2b-Interferon have been developed. The drug purity was approximately 97-98%. Biological activity in the culture of sensory cells in the cytopathic test was 4.2*10(8)ME/mg.

A I Melnik - One of the best experts on this subject based on the ideXlab platform.

  • production of purified human Recombinant Alpha2b Interferon
    2012
    Co-Authors: A I Melnik, N M Zholobak, Spivak Nia
    Abstract:

    Technology for producing biologically active Recombinant Alpha2b-Interferon is based on creating a bacterial producer strain containing the cDNA of human Interferon alpha. The authors have obtained two producers of Recombinant Alpha2b-Interferon, the synthesis of the target protein in them occurs in the inclusion bodies. The schemes of isolation and purification of biologically active Recombinant Alpha2b-Interferon have been developed. The drug purity was approximately 97-98%. Biological activity in the culture of sensory cells in the cytopathic test was 4.2*10(8)ME/mg.

N M Zholobak - One of the best experts on this subject based on the ideXlab platform.

  • production of purified human Recombinant Alpha2b Interferon
    2012
    Co-Authors: A I Melnik, N M Zholobak, Spivak Nia
    Abstract:

    Technology for producing biologically active Recombinant Alpha2b-Interferon is based on creating a bacterial producer strain containing the cDNA of human Interferon alpha. The authors have obtained two producers of Recombinant Alpha2b-Interferon, the synthesis of the target protein in them occurs in the inclusion bodies. The schemes of isolation and purification of biologically active Recombinant Alpha2b-Interferon have been developed. The drug purity was approximately 97-98%. Biological activity in the culture of sensory cells in the cytopathic test was 4.2*10(8)ME/mg.