The Experts below are selected from a list of 48360 Experts worldwide ranked by ideXlab platform

Gleb B. Sukhorukov - One of the best experts on this subject based on the ideXlab platform.

  • In Situ Synthesis of Fluorescent Carbon Dots/Polyelectrolyte Nanocomposite Microcapsules with Reduced Permeability and Ultrasound Sensitivity.
    ACS nano, 2016
    Co-Authors: Hui Gao, Andrei Sapelkin, Magdalena M. Titirici, Gleb B. Sukhorukov
    Abstract:

    Designing and fabricating multifunctional nanocomposite microcapsules are considerable interests in both academic and industrial research aspects. This work first reports an innovative approach to in situ synthesize and assemble fluorescent carbon dots (CDs) into polyelectrolyte microcapsules, obtaining highly biocompatible nanocomposite microcapsules with excellent luminescence that facilitate imaging and identification in vitro, yet with the feasibility to load small molecules and ultrasound responsiveness to trigger their release. CDs are produced in situ in (PAH/PSS)4 microcapsule shells by carbonization of dextran molecules under relatively mild hydrothermal treatment. Compared with the collapsed and film-like (PAH/PSS)4 microcapsules, the novel composite microcapsules show a free-standing structure, smaller size, and thicker shell. CDs are proven to be fabricated and embedded in PAH/PSS multilayers, and the formed PAH/PSS/CD microcapsules are endowed with strong luminescence, as verified by the tran...

  • in situ synthesis of fluorescent carbon dots polyelectrolyte nanocomposite microcapsules with Reduced Permeability and ultrasound sensitivity
    ACS Nano, 2016
    Co-Authors: Hui Gao, Andrei Sapelkin, Magdalena M. Titirici, Gleb B. Sukhorukov
    Abstract:

    Designing and fabricating multifunctional nanocomposite microcapsules are considerable interests in both academic and industrial research aspects. This work first reports an innovative approach to in situ synthesize and assemble fluorescent carbon dots (CDs) into polyelectrolyte microcapsules, obtaining highly biocompatible nanocomposite microcapsules with excellent luminescence that facilitate imaging and identification in vitro, yet with the feasibility to load small molecules and ultrasound responsiveness to trigger their release. CDs are produced in situ in (PAH/PSS)4 microcapsule shells by carbonization of dextran molecules under relatively mild hydrothermal treatment. Compared with the collapsed and film-like (PAH/PSS)4 microcapsules, the novel composite microcapsules show a free-standing structure, smaller size, and thicker shell. CDs are proven to be fabricated and embedded in PAH/PSS multilayers, and the formed PAH/PSS/CD microcapsules are endowed with strong luminescence, as verified by the tran...

  • composite silica nanoparticle polyelectrolyte microcapsules with Reduced Permeability and enhanced ultrasound sensitivity
    Journal of Materials Chemistry B, 2015
    Co-Authors: Hui Gao, Dongsheng Wen, Gleb B. Sukhorukov
    Abstract:

    Many chemical and biomedical systems require delivery and controlled release of small molecules, which cannot be achieved by conventional polyelectrolyte-based layer-by-layer capsules. This work proposes an innovative hybrid microcapsule by incorporating in situ formed silica nanoparticles within or on the shell. The influence of various experimental conditions on the stability, mechanical strength and morphology of capsules was investigated and characterised by SEM, TEM, XRD, EDX and FTIR. The multifunctional capabilities of the formed capsules were examined by encapsulating a small molecule rhodamine B (Rh-B) which could be further released by an ultrasonic trigger. The results show that in situ formed SiO2 nanoparticles through hydrolysis greatly Reduced the Permeability of the shell yet showed increased mechanical strength and ultrasound response. SiO2 nanoparticles were shown to be distributed on the surface or inside the polyelectrolyte shell, acting as supports for free-standing capsules in both liquid and dry environments. Rapid Rh-B molecule release and the fragmentation of the capsule shells were observed under 50 W ultrasound irradiation for a few seconds. Such innovative capsules with the capability of small molecule encapsulation and high ultrasound sensitivity could be promising for many applications where pulse release of small molecules is required.

  • Composite silica nanoparticle/polyelectrolyte microcapsules with Reduced Permeability and enhanced ultrasound sensitivity.
    Journal of materials chemistry. B, 2015
    Co-Authors: Hui Gao, Dongsheng Wen, Gleb B. Sukhorukov
    Abstract:

    Many chemical and biomedical systems require delivery and controlled release of small molecules, which cannot be achieved by conventional polyelectrolyte-based layer-by-layer capsules. This work proposes an innovative hybrid microcapsule by incorporating in situ formed silica nanoparticles within or on the shell. The influence of various experimental conditions on the stability, mechanical strength and morphology of capsules was investigated and characterised by SEM, TEM, XRD, EDX and FTIR. The multifunctional capabilities of the formed capsules were examined by encapsulating a small molecule rhodamine B (Rh-B) which could be further released by an ultrasonic trigger. The results show that in situ formed SiO2 nanoparticles through hydrolysis greatly Reduced the Permeability of the shell yet showed increased mechanical strength and ultrasound response. SiO2 nanoparticles were shown to be distributed on the surface or inside the polyelectrolyte shell, acting as supports for free-standing capsules in both liquid and dry environments. Rapid Rh-B molecule release and the fragmentation of the capsule shells were observed under 50 W ultrasound irradiation for a few seconds. Such innovative capsules with the capability of small molecule encapsulation and high ultrasound sensitivity could be promising for many applications where pulse release of small molecules is required.

Hui Gao - One of the best experts on this subject based on the ideXlab platform.

  • In Situ Synthesis of Fluorescent Carbon Dots/Polyelectrolyte Nanocomposite Microcapsules with Reduced Permeability and Ultrasound Sensitivity.
    ACS nano, 2016
    Co-Authors: Hui Gao, Andrei Sapelkin, Magdalena M. Titirici, Gleb B. Sukhorukov
    Abstract:

    Designing and fabricating multifunctional nanocomposite microcapsules are considerable interests in both academic and industrial research aspects. This work first reports an innovative approach to in situ synthesize and assemble fluorescent carbon dots (CDs) into polyelectrolyte microcapsules, obtaining highly biocompatible nanocomposite microcapsules with excellent luminescence that facilitate imaging and identification in vitro, yet with the feasibility to load small molecules and ultrasound responsiveness to trigger their release. CDs are produced in situ in (PAH/PSS)4 microcapsule shells by carbonization of dextran molecules under relatively mild hydrothermal treatment. Compared with the collapsed and film-like (PAH/PSS)4 microcapsules, the novel composite microcapsules show a free-standing structure, smaller size, and thicker shell. CDs are proven to be fabricated and embedded in PAH/PSS multilayers, and the formed PAH/PSS/CD microcapsules are endowed with strong luminescence, as verified by the tran...

  • in situ synthesis of fluorescent carbon dots polyelectrolyte nanocomposite microcapsules with Reduced Permeability and ultrasound sensitivity
    ACS Nano, 2016
    Co-Authors: Hui Gao, Andrei Sapelkin, Magdalena M. Titirici, Gleb B. Sukhorukov
    Abstract:

    Designing and fabricating multifunctional nanocomposite microcapsules are considerable interests in both academic and industrial research aspects. This work first reports an innovative approach to in situ synthesize and assemble fluorescent carbon dots (CDs) into polyelectrolyte microcapsules, obtaining highly biocompatible nanocomposite microcapsules with excellent luminescence that facilitate imaging and identification in vitro, yet with the feasibility to load small molecules and ultrasound responsiveness to trigger their release. CDs are produced in situ in (PAH/PSS)4 microcapsule shells by carbonization of dextran molecules under relatively mild hydrothermal treatment. Compared with the collapsed and film-like (PAH/PSS)4 microcapsules, the novel composite microcapsules show a free-standing structure, smaller size, and thicker shell. CDs are proven to be fabricated and embedded in PAH/PSS multilayers, and the formed PAH/PSS/CD microcapsules are endowed with strong luminescence, as verified by the tran...

  • composite silica nanoparticle polyelectrolyte microcapsules with Reduced Permeability and enhanced ultrasound sensitivity
    Journal of Materials Chemistry B, 2015
    Co-Authors: Hui Gao, Dongsheng Wen, Gleb B. Sukhorukov
    Abstract:

    Many chemical and biomedical systems require delivery and controlled release of small molecules, which cannot be achieved by conventional polyelectrolyte-based layer-by-layer capsules. This work proposes an innovative hybrid microcapsule by incorporating in situ formed silica nanoparticles within or on the shell. The influence of various experimental conditions on the stability, mechanical strength and morphology of capsules was investigated and characterised by SEM, TEM, XRD, EDX and FTIR. The multifunctional capabilities of the formed capsules were examined by encapsulating a small molecule rhodamine B (Rh-B) which could be further released by an ultrasonic trigger. The results show that in situ formed SiO2 nanoparticles through hydrolysis greatly Reduced the Permeability of the shell yet showed increased mechanical strength and ultrasound response. SiO2 nanoparticles were shown to be distributed on the surface or inside the polyelectrolyte shell, acting as supports for free-standing capsules in both liquid and dry environments. Rapid Rh-B molecule release and the fragmentation of the capsule shells were observed under 50 W ultrasound irradiation for a few seconds. Such innovative capsules with the capability of small molecule encapsulation and high ultrasound sensitivity could be promising for many applications where pulse release of small molecules is required.

  • Composite silica nanoparticle/polyelectrolyte microcapsules with Reduced Permeability and enhanced ultrasound sensitivity.
    Journal of materials chemistry. B, 2015
    Co-Authors: Hui Gao, Dongsheng Wen, Gleb B. Sukhorukov
    Abstract:

    Many chemical and biomedical systems require delivery and controlled release of small molecules, which cannot be achieved by conventional polyelectrolyte-based layer-by-layer capsules. This work proposes an innovative hybrid microcapsule by incorporating in situ formed silica nanoparticles within or on the shell. The influence of various experimental conditions on the stability, mechanical strength and morphology of capsules was investigated and characterised by SEM, TEM, XRD, EDX and FTIR. The multifunctional capabilities of the formed capsules were examined by encapsulating a small molecule rhodamine B (Rh-B) which could be further released by an ultrasonic trigger. The results show that in situ formed SiO2 nanoparticles through hydrolysis greatly Reduced the Permeability of the shell yet showed increased mechanical strength and ultrasound response. SiO2 nanoparticles were shown to be distributed on the surface or inside the polyelectrolyte shell, acting as supports for free-standing capsules in both liquid and dry environments. Rapid Rh-B molecule release and the fragmentation of the capsule shells were observed under 50 W ultrasound irradiation for a few seconds. Such innovative capsules with the capability of small molecule encapsulation and high ultrasound sensitivity could be promising for many applications where pulse release of small molecules is required.

Pietro Asinari - One of the best experts on this subject based on the ideXlab platform.

  • Interplay between hydrophilicity and surface barriers on water transport in zeolite membranes
    Nature communications, 2016
    Co-Authors: Matteo Fasano, Thomas Humplik, Alessio Bevilacqua, Michael Tsapatsis, Eliodoro Chiavazzo, Evelyn N. Wang, Pietro Asinari
    Abstract:

    A comprehensive understanding of molecular transport within nanoporous materials remains elusive in a broad variety of engineering and biomedical applications. Here, experiments and atomistic simulations are synergically used to elucidate the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water transport through zeolite crystals. At these nanometre-length scales, these results highlight the dominating effect of surface imperfections with Reduced Permeability on the overall water transport. A simple diffusion resistance model is shown to be sufficient to capture the effects of both intracrystalline and surface diffusion resistances, thus properly linking simulation to experimental evidence. This work suggests that future experimental work should focus on eliminating/overcoming these surface imperfections, which promise an order of magnitude improvement in Permeability.

  • Interplay between hydrophilicity and surface barriers on water transport in zeolite membranes
    Nature Communications, 2016
    Co-Authors: Matteo Fasano, Thomas Humplik, Alessio Bevilacqua, Michael Tsapatsis, Eliodoro Chiavazzo, Evelyn N. Wang, Pietro Asinari
    Abstract:

    Zeolite crystal with porous structure is predicted to be a good membrane material for water purification, but experiments show water uptake orders of magnitude smaller than the theory. Here, Fasano et al . attribute this disagreement to the additional diffusion resistance induced by surface defects. A comprehensive understanding of molecular transport within nanoporous materials remains elusive in a broad variety of engineering and biomedical applications. Here, experiments and atomistic simulations are synergically used to elucidate the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water transport through zeolite crystals. At these nanometre-length scales, these results highlight the dominating effect of surface imperfections with Reduced Permeability on the overall water transport. A simple diffusion resistance model is shown to be sufficient to capture the effects of both intracrystalline and surface diffusion resistances, thus properly linking simulation to experimental evidence. This work suggests that future experimental work should focus on eliminating/overcoming these surface imperfections, which promise an order of magnitude improvement in Permeability.

Matteo Fasano - One of the best experts on this subject based on the ideXlab platform.

  • Interplay between hydrophilicity and surface barriers on water transport in zeolite membranes
    Nature communications, 2016
    Co-Authors: Matteo Fasano, Thomas Humplik, Alessio Bevilacqua, Michael Tsapatsis, Eliodoro Chiavazzo, Evelyn N. Wang, Pietro Asinari
    Abstract:

    A comprehensive understanding of molecular transport within nanoporous materials remains elusive in a broad variety of engineering and biomedical applications. Here, experiments and atomistic simulations are synergically used to elucidate the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water transport through zeolite crystals. At these nanometre-length scales, these results highlight the dominating effect of surface imperfections with Reduced Permeability on the overall water transport. A simple diffusion resistance model is shown to be sufficient to capture the effects of both intracrystalline and surface diffusion resistances, thus properly linking simulation to experimental evidence. This work suggests that future experimental work should focus on eliminating/overcoming these surface imperfections, which promise an order of magnitude improvement in Permeability.

  • Interplay between hydrophilicity and surface barriers on water transport in zeolite membranes
    Nature Communications, 2016
    Co-Authors: Matteo Fasano, Thomas Humplik, Alessio Bevilacqua, Michael Tsapatsis, Eliodoro Chiavazzo, Evelyn N. Wang, Pietro Asinari
    Abstract:

    Zeolite crystal with porous structure is predicted to be a good membrane material for water purification, but experiments show water uptake orders of magnitude smaller than the theory. Here, Fasano et al . attribute this disagreement to the additional diffusion resistance induced by surface defects. A comprehensive understanding of molecular transport within nanoporous materials remains elusive in a broad variety of engineering and biomedical applications. Here, experiments and atomistic simulations are synergically used to elucidate the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water transport through zeolite crystals. At these nanometre-length scales, these results highlight the dominating effect of surface imperfections with Reduced Permeability on the overall water transport. A simple diffusion resistance model is shown to be sufficient to capture the effects of both intracrystalline and surface diffusion resistances, thus properly linking simulation to experimental evidence. This work suggests that future experimental work should focus on eliminating/overcoming these surface imperfections, which promise an order of magnitude improvement in Permeability.

Evelyn N. Wang - One of the best experts on this subject based on the ideXlab platform.

  • Interplay between hydrophilicity and surface barriers on water transport in zeolite membranes
    Nature communications, 2016
    Co-Authors: Matteo Fasano, Thomas Humplik, Alessio Bevilacqua, Michael Tsapatsis, Eliodoro Chiavazzo, Evelyn N. Wang, Pietro Asinari
    Abstract:

    A comprehensive understanding of molecular transport within nanoporous materials remains elusive in a broad variety of engineering and biomedical applications. Here, experiments and atomistic simulations are synergically used to elucidate the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water transport through zeolite crystals. At these nanometre-length scales, these results highlight the dominating effect of surface imperfections with Reduced Permeability on the overall water transport. A simple diffusion resistance model is shown to be sufficient to capture the effects of both intracrystalline and surface diffusion resistances, thus properly linking simulation to experimental evidence. This work suggests that future experimental work should focus on eliminating/overcoming these surface imperfections, which promise an order of magnitude improvement in Permeability.

  • Interplay between hydrophilicity and surface barriers on water transport in zeolite membranes
    Nature Communications, 2016
    Co-Authors: Matteo Fasano, Thomas Humplik, Alessio Bevilacqua, Michael Tsapatsis, Eliodoro Chiavazzo, Evelyn N. Wang, Pietro Asinari
    Abstract:

    Zeolite crystal with porous structure is predicted to be a good membrane material for water purification, but experiments show water uptake orders of magnitude smaller than the theory. Here, Fasano et al . attribute this disagreement to the additional diffusion resistance induced by surface defects. A comprehensive understanding of molecular transport within nanoporous materials remains elusive in a broad variety of engineering and biomedical applications. Here, experiments and atomistic simulations are synergically used to elucidate the non-trivial interplay between nanopore hydrophilicity and surface barriers on the overall water transport through zeolite crystals. At these nanometre-length scales, these results highlight the dominating effect of surface imperfections with Reduced Permeability on the overall water transport. A simple diffusion resistance model is shown to be sufficient to capture the effects of both intracrystalline and surface diffusion resistances, thus properly linking simulation to experimental evidence. This work suggests that future experimental work should focus on eliminating/overcoming these surface imperfections, which promise an order of magnitude improvement in Permeability.