The Experts below are selected from a list of 35760 Experts worldwide ranked by ideXlab platform
Andrea Münsterberg - One of the best experts on this subject based on the ideXlab platform.
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4d imaging reveals stage dependent random and directed cell motion during somite morphogenesis
Scientific Reports, 2018Co-Authors: James Mccoll, Gi Fay Mok, Anna Lippert, Aleks Ponjavic, Leila Muresan, Andrea MünsterbergAbstract:Somites are paired embryonic segments that form in a Regular Sequence from unsegmented mesoderm during vertebrate development. Although transient structures they are of fundamental importance as they generate cell lineages of the musculoskeletal system in the trunk such as cartilage, tendon, bone, endothelial cells and skeletal muscle. Surprisingly, very little is known about cellular dynamics underlying the morphological transitions during somite differentiation. Here, we address this by examining cellular rearrangements and morphogenesis in differentiating somites using live multi-photon imaging of transgenic chick embryos, where all cells express a membrane-bound GFP. We specifically focussed on the dynamic cellular changes in two principle regions within the somite, the medial and lateral domains, to investigate extensive morphological transformations. Furthermore, by using quantitative analysis and cell tracking, we capture for the first time a directed movement of dermomyotomal progenitor cells towards the rostro-medial domain of the dermomyotome, where skeletal muscle formation initiates.
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4d imaging reveals stage dependent random and directed cell motion during somite morphogenesis
bioRxiv, 2018Co-Authors: James Mccoll, Gi Fay Mok, Anna Lippert, Aleks Ponjavic, Leila Muresan, Andrea MünsterbergAbstract:Somites are paired embryonic segments that form in a Regular Sequence from unsegmented mesoderm during vertebrate development. Of fundamental importance, they are transient structures that generate cell lineages of the musculoskeletal system in the trunk such as cartilage, tendon, bone, endothelial cells and skeletal muscle. Surprisingly, very little is known about the morphological transition and cellular dynamics during somite differentiation. Here, we address this by examining cellular rearrangements and morphogenesis in differentiating somites using live multi photon imaging of GFP-transgenic chick embryos. We specifically focussed on the dynamic changes in two principle regions within the somite (the medial and lateral domains) to investigate extensive morphological changes. Furthermore, by using quantitative analysis and cell tracking, we were able to capture for the first time a progenitor cell bulk movement towards the rostral-medial domain of the myotome, where skeletal muscle formation first initiates.
Adem Kilicman - One of the best experts on this subject based on the ideXlab platform.
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on the composition and neutrix composition of the delta function with the hyperbolic tangent and its inverse functions
Journal of Applied Mathematics, 2011Co-Authors: Brian Fisher, Adem KilicmanAbstract:Let F be a distribution in D' and let f be a locally summable function. The composition F(f(x)) of F and f is said to exist and be equal to the distribution h(x) if the limit of the Sequence {Fn(f(x))} is equal to h(x), where Fn(x)=F(x)*δn(x) for n=1,2,… and {δn(x)} is a certain Regular Sequence converging to the Dirac delta function. It is proved that the neutrix composition δ(rs-1)((tanhx
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on the neutrix composition of the delta and inverse hyperbolic sine functions
Journal of Applied Mathematics, 2011Co-Authors: Brian Fisher, Adem KilicmanAbstract:Let be a distribution in and let be a locally summable function. The composition of and is said to exist and be equal to the distribution if the limit of the Sequence is equal to , where for and is a certain Regular Sequence converging to the Dirac delta function. In the ordinary sense, the composition does not exists. In this study, it is proved that the neutrix composition exists and is given by , for and , where . Further results are also proved.
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on the composition and neutrix composition of the delta function and powers of the inverse hyperbolic sine function
Integral Transforms and Special Functions, 2010Co-Authors: Brian Fisher, Adem KilicmanAbstract:Let F be a distribution in 𝒟′ and let f be a locally summable function. The composition F(f(x)) of F and f is said to exist and be equal to the distribution h(x) if the limit of the Sequence {F n (f(x))} is equal to h(x), where F n (x)=F(x)*δ n (x) for n=1, 2, … and {δ n (x)} is a certain Regular Sequence converging to the Dirac delta function. It is proved that the neutrix composition δ(s)[(sinh−1 x +)1/r ] exists and for s=0, 1, 2, … and r=1, 2, …, where M is the smallest integer greater than (s−r 2+1)/r and Further results are also proved.
James Mccoll - One of the best experts on this subject based on the ideXlab platform.
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4d imaging reveals stage dependent random and directed cell motion during somite morphogenesis
Scientific Reports, 2018Co-Authors: James Mccoll, Gi Fay Mok, Anna Lippert, Aleks Ponjavic, Leila Muresan, Andrea MünsterbergAbstract:Somites are paired embryonic segments that form in a Regular Sequence from unsegmented mesoderm during vertebrate development. Although transient structures they are of fundamental importance as they generate cell lineages of the musculoskeletal system in the trunk such as cartilage, tendon, bone, endothelial cells and skeletal muscle. Surprisingly, very little is known about cellular dynamics underlying the morphological transitions during somite differentiation. Here, we address this by examining cellular rearrangements and morphogenesis in differentiating somites using live multi-photon imaging of transgenic chick embryos, where all cells express a membrane-bound GFP. We specifically focussed on the dynamic cellular changes in two principle regions within the somite, the medial and lateral domains, to investigate extensive morphological transformations. Furthermore, by using quantitative analysis and cell tracking, we capture for the first time a directed movement of dermomyotomal progenitor cells towards the rostro-medial domain of the dermomyotome, where skeletal muscle formation initiates.
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4d imaging reveals stage dependent random and directed cell motion during somite morphogenesis
bioRxiv, 2018Co-Authors: James Mccoll, Gi Fay Mok, Anna Lippert, Aleks Ponjavic, Leila Muresan, Andrea MünsterbergAbstract:Somites are paired embryonic segments that form in a Regular Sequence from unsegmented mesoderm during vertebrate development. Of fundamental importance, they are transient structures that generate cell lineages of the musculoskeletal system in the trunk such as cartilage, tendon, bone, endothelial cells and skeletal muscle. Surprisingly, very little is known about the morphological transition and cellular dynamics during somite differentiation. Here, we address this by examining cellular rearrangements and morphogenesis in differentiating somites using live multi photon imaging of GFP-transgenic chick embryos. We specifically focussed on the dynamic changes in two principle regions within the somite (the medial and lateral domains) to investigate extensive morphological changes. Furthermore, by using quantitative analysis and cell tracking, we were able to capture for the first time a progenitor cell bulk movement towards the rostral-medial domain of the myotome, where skeletal muscle formation first initiates.
Brian Fisher - One of the best experts on this subject based on the ideXlab platform.
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on the composition and neutrix composition of the delta function with the hyperbolic tangent and its inverse functions
Journal of Applied Mathematics, 2011Co-Authors: Brian Fisher, Adem KilicmanAbstract:Let F be a distribution in D' and let f be a locally summable function. The composition F(f(x)) of F and f is said to exist and be equal to the distribution h(x) if the limit of the Sequence {Fn(f(x))} is equal to h(x), where Fn(x)=F(x)*δn(x) for n=1,2,… and {δn(x)} is a certain Regular Sequence converging to the Dirac delta function. It is proved that the neutrix composition δ(rs-1)((tanhx
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on the neutrix composition of the delta and inverse hyperbolic sine functions
Journal of Applied Mathematics, 2011Co-Authors: Brian Fisher, Adem KilicmanAbstract:Let be a distribution in and let be a locally summable function. The composition of and is said to exist and be equal to the distribution if the limit of the Sequence is equal to , where for and is a certain Regular Sequence converging to the Dirac delta function. In the ordinary sense, the composition does not exists. In this study, it is proved that the neutrix composition exists and is given by , for and , where . Further results are also proved.
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on the composition and neutrix composition of the delta function and powers of the inverse hyperbolic sine function
Integral Transforms and Special Functions, 2010Co-Authors: Brian Fisher, Adem KilicmanAbstract:Let F be a distribution in 𝒟′ and let f be a locally summable function. The composition F(f(x)) of F and f is said to exist and be equal to the distribution h(x) if the limit of the Sequence {F n (f(x))} is equal to h(x), where F n (x)=F(x)*δ n (x) for n=1, 2, … and {δ n (x)} is a certain Regular Sequence converging to the Dirac delta function. It is proved that the neutrix composition δ(s)[(sinh−1 x +)1/r ] exists and for s=0, 1, 2, … and r=1, 2, …, where M is the smallest integer greater than (s−r 2+1)/r and Further results are also proved.
Anna Lippert - One of the best experts on this subject based on the ideXlab platform.
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4d imaging reveals stage dependent random and directed cell motion during somite morphogenesis
Scientific Reports, 2018Co-Authors: James Mccoll, Gi Fay Mok, Anna Lippert, Aleks Ponjavic, Leila Muresan, Andrea MünsterbergAbstract:Somites are paired embryonic segments that form in a Regular Sequence from unsegmented mesoderm during vertebrate development. Although transient structures they are of fundamental importance as they generate cell lineages of the musculoskeletal system in the trunk such as cartilage, tendon, bone, endothelial cells and skeletal muscle. Surprisingly, very little is known about cellular dynamics underlying the morphological transitions during somite differentiation. Here, we address this by examining cellular rearrangements and morphogenesis in differentiating somites using live multi-photon imaging of transgenic chick embryos, where all cells express a membrane-bound GFP. We specifically focussed on the dynamic cellular changes in two principle regions within the somite, the medial and lateral domains, to investigate extensive morphological transformations. Furthermore, by using quantitative analysis and cell tracking, we capture for the first time a directed movement of dermomyotomal progenitor cells towards the rostro-medial domain of the dermomyotome, where skeletal muscle formation initiates.
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4d imaging reveals stage dependent random and directed cell motion during somite morphogenesis
bioRxiv, 2018Co-Authors: James Mccoll, Gi Fay Mok, Anna Lippert, Aleks Ponjavic, Leila Muresan, Andrea MünsterbergAbstract:Somites are paired embryonic segments that form in a Regular Sequence from unsegmented mesoderm during vertebrate development. Of fundamental importance, they are transient structures that generate cell lineages of the musculoskeletal system in the trunk such as cartilage, tendon, bone, endothelial cells and skeletal muscle. Surprisingly, very little is known about the morphological transition and cellular dynamics during somite differentiation. Here, we address this by examining cellular rearrangements and morphogenesis in differentiating somites using live multi photon imaging of GFP-transgenic chick embryos. We specifically focussed on the dynamic changes in two principle regions within the somite (the medial and lateral domains) to investigate extensive morphological changes. Furthermore, by using quantitative analysis and cell tracking, we were able to capture for the first time a progenitor cell bulk movement towards the rostral-medial domain of the myotome, where skeletal muscle formation first initiates.
