The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform
Simone S Aguiar - One of the best experts on this subject based on the ideXlab platform.
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a unique case of synchronous functional adrenocortical adenoma and myelolipoma within the ectopic adRenal cortex in a child with beckwith wiedemann syndrome
Pathology Research and Practice, 2012Co-Authors: Izilda A Cardinalli, Antonio Goncalves De Oliveirafilho, Maria Jose Mastellaro, Raul C Ribeiro, Simone S AguiarAbstract:We report a unique case of synchronous functional adrenocortical adenoma and an incidental myelolipoma within ectopic cortical adRenal tissue located in the Renal Hilum in a child with Beckwith-Wiedemann syndrome and review the association between adRenal gland disorders and myelolipomas. To the best of our knowledge, this is the first documented case of a simultaneous occurrence of these three conditions. A 17-month-old child with Beckwith-Wiedemann syndrome was diagnosed with a left adRenal tumor during complementary radiologic studies. Biochemical investigation before surgery showed elevated blood levels of cortisol and dehydroepiandrosterone hormones. The patient underwent a left adRenalectomy with ipsilateral Renal hilar and intercaval-aortic lymph node dissection. Pathology findings revealed a left adrenocortical adenoma and an incidental myelolipoma growing within ectopic cortical adRenal tissue in the Renal Hilum. The patient is doing well and does not have any current health issues. Patients with adRenal cortex disorders, such as hyperplasias and neoplasms, particularly when associated with hormonal imbalances, may have an increased risk of developing myelolipomas. Whether Beckwith-Wiedemann syndrome may, by itself, contribute to simultaneous occurrence of adrenocortical adenomas and myelolipomas remains to be clarified.
Guanghua Liu - One of the best experts on this subject based on the ideXlab platform.
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Ectopic cortisol-producing adrenocortical adenoma in the Renal Hilum: histopathological features and steroidogenic enzyme profile.
International journal of clinical and experimental pathology, 2014Co-Authors: Anli Tong, Aihua Jia, Shujie Yan, Yan Zhang, Yi Xie, Guanghua LiuAbstract:Ectopic cortisol-producing adrenocortical adenomas (CPA) are extremely rare, and only four cases have previously been reported so far but the tumors were not ultrastructurally studied. Presented in this paper is the fifth case with ectopic CPA which was extensively examined to gain deeper insights in terms of the histopathological features and steroidogenic enzyme profile of the tumor. A 53-year-old woman complained of accidental discovery of left Renal mass. She had a 5-year history of hypertension, weight gain, moon face, thin skin and systemic edema. These symptoms completely relieved after the tumor removal. Two years later, the above symptoms recurred, and a recurrent tumor was revealed in left Renal Hilum. The tumor was removed completely with relief of her symptoms of Cushing’s syndrome. Histologically and ultrastructurally, the tumor was composed of compact cells and clear cells, and the former was prominent, suggesting an active secretory function of the tumor. The adenoma tissue showed a strong immunostaining for Melan-A, 3beta-hydroxysteroid dehydrogenase (HSD3B2) and 17alpha-hydroxylase1 (CYP17A1). Expression pattern for 11beta-hydroxylase 1 (CYP11B1), 11beta-hydroxylase 2 (CYP11B2), CYP17 and HSD3B2 mRNA in ectopic CPA was similar to that in the adRenal CPA. In conclusion, in terms of histopathological characteristic and steroidogenic enzyme profile, ectopic CPA is similar to adRenal CPA, suggesting that they are of identical cell origin.
Izilda A Cardinalli - One of the best experts on this subject based on the ideXlab platform.
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a unique case of synchronous functional adrenocortical adenoma and myelolipoma within the ectopic adRenal cortex in a child with beckwith wiedemann syndrome
Pathology Research and Practice, 2012Co-Authors: Izilda A Cardinalli, Antonio Goncalves De Oliveirafilho, Maria Jose Mastellaro, Raul C Ribeiro, Simone S AguiarAbstract:We report a unique case of synchronous functional adrenocortical adenoma and an incidental myelolipoma within ectopic cortical adRenal tissue located in the Renal Hilum in a child with Beckwith-Wiedemann syndrome and review the association between adRenal gland disorders and myelolipomas. To the best of our knowledge, this is the first documented case of a simultaneous occurrence of these three conditions. A 17-month-old child with Beckwith-Wiedemann syndrome was diagnosed with a left adRenal tumor during complementary radiologic studies. Biochemical investigation before surgery showed elevated blood levels of cortisol and dehydroepiandrosterone hormones. The patient underwent a left adRenalectomy with ipsilateral Renal hilar and intercaval-aortic lymph node dissection. Pathology findings revealed a left adrenocortical adenoma and an incidental myelolipoma growing within ectopic cortical adRenal tissue in the Renal Hilum. The patient is doing well and does not have any current health issues. Patients with adRenal cortex disorders, such as hyperplasias and neoplasms, particularly when associated with hormonal imbalances, may have an increased risk of developing myelolipomas. Whether Beckwith-Wiedemann syndrome may, by itself, contribute to simultaneous occurrence of adrenocortical adenomas and myelolipomas remains to be clarified.
Louis R. Kavoussi - One of the best experts on this subject based on the ideXlab platform.
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Rapid ligation of Renal Hilum during transperitoneal laparoscopic nephrectomy
Urology, 2001Co-Authors: David Y. Chan, Louis R. KavoussiAbstract:We describe our surgical technique for rapid ligation of the Renal Hilum during transperitoneal laparoscopic nephrectomy. This technique is reliable and provides an efficient method of hilar ligation.
Anli Tong - One of the best experts on this subject based on the ideXlab platform.
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Ectopic cortisol-producing adrenocortical adenoma in the Renal Hilum: histopathological features and steroidogenic enzyme profile.
International journal of clinical and experimental pathology, 2014Co-Authors: Anli Tong, Aihua Jia, Shujie Yan, Yan Zhang, Yi Xie, Guanghua LiuAbstract:Ectopic cortisol-producing adrenocortical adenomas (CPA) are extremely rare, and only four cases have previously been reported so far but the tumors were not ultrastructurally studied. Presented in this paper is the fifth case with ectopic CPA which was extensively examined to gain deeper insights in terms of the histopathological features and steroidogenic enzyme profile of the tumor. A 53-year-old woman complained of accidental discovery of left Renal mass. She had a 5-year history of hypertension, weight gain, moon face, thin skin and systemic edema. These symptoms completely relieved after the tumor removal. Two years later, the above symptoms recurred, and a recurrent tumor was revealed in left Renal Hilum. The tumor was removed completely with relief of her symptoms of Cushing’s syndrome. Histologically and ultrastructurally, the tumor was composed of compact cells and clear cells, and the former was prominent, suggesting an active secretory function of the tumor. The adenoma tissue showed a strong immunostaining for Melan-A, 3beta-hydroxysteroid dehydrogenase (HSD3B2) and 17alpha-hydroxylase1 (CYP17A1). Expression pattern for 11beta-hydroxylase 1 (CYP11B1), 11beta-hydroxylase 2 (CYP11B2), CYP17 and HSD3B2 mRNA in ectopic CPA was similar to that in the adRenal CPA. In conclusion, in terms of histopathological characteristic and steroidogenic enzyme profile, ectopic CPA is similar to adRenal CPA, suggesting that they are of identical cell origin.