Renal Pelvis

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Sonny L Johansson - One of the best experts on this subject based on the ideXlab platform.

  • squamous cell carcinoma of the Renal Pelvis and ureter incidence symptoms treatment and outcome
    The Journal of Urology, 2007
    Co-Authors: Sten Holmang, Subodh M Lele, Sonny L Johansson
    Abstract:

    Purpose: Squamous cell carcinomas of the Renal Pelvis and ureter are rare. We report a large series of patients and compare it to patients with urothelial carcinoma.Materials and Methods: The initial material was comprised of 808 patients with Renal Pelvis or ureteral cancer. A review of the histopathological material and clinical records was performed.Results: Only 2 (4%) of 65 patients with squamous cell carcinoma had stage pTa/pT1/pT2 tumors compared to 460 (62%) of 743 patients with urothelial carcinoma. Median survival was much shorter for surgically treated patients with squamous cell carcinoma compared to those with urothelial carcinoma (7 vs 50 months). However, there was no significant difference in the disease specific 5-year survival rate between patients with squamous cell carcinoma and urothelial carcinoma in the same disease stage. Vascular invasion, microscopic solid tumor pattern and large tumor size had negative prognostic significance in multivariate analyses. Histopathological tumor typ...

  • micropapillary carcinoma of the Renal Pelvis and ureter
    The Journal of Urology, 2006
    Co-Authors: Sten Holmang, Jean Thomsen, Sonny L Johansson
    Abstract:

    Purpose: MPC located in the upper urinary tract is rare with only 2 cases reported to date. We report clinical and histopathological data on 26 patients to increase the knowledge of this rare entity.Materials and Methods: A clinical and histopathological review was performed in 943 patients with a neoplasm in the Renal Pelvis or ureter, diagnosed between 1971 and 1998. We identified 26 patients with MPC. No patients were alive at the end of the study.Results: Of the patients 11 had greater than 50% MPC and 15 had focal MPC (at least 10%). The incidence was 2.8%. Median patient age at diagnosis was 69 years (range 54 to 88) and the male-to-female ratio was 17:9. All except 4 patients had stage T3 disease or higher. Carcinoma in situ was identified in 64% of cases and vascular invasion was present in 81%. A total of 20 patients (77%) died of disease and only 7 survived longer than 5 years.Conclusions: The prognosis is poor since most patients with MPC of the Renal Pelvis and ureter initially present with ad...

Antony Devasia - One of the best experts on this subject based on the ideXlab platform.

Sten Holmang - One of the best experts on this subject based on the ideXlab platform.

  • squamous cell carcinoma of the Renal Pelvis and ureter incidence symptoms treatment and outcome
    The Journal of Urology, 2007
    Co-Authors: Sten Holmang, Subodh M Lele, Sonny L Johansson
    Abstract:

    Purpose: Squamous cell carcinomas of the Renal Pelvis and ureter are rare. We report a large series of patients and compare it to patients with urothelial carcinoma.Materials and Methods: The initial material was comprised of 808 patients with Renal Pelvis or ureteral cancer. A review of the histopathological material and clinical records was performed.Results: Only 2 (4%) of 65 patients with squamous cell carcinoma had stage pTa/pT1/pT2 tumors compared to 460 (62%) of 743 patients with urothelial carcinoma. Median survival was much shorter for surgically treated patients with squamous cell carcinoma compared to those with urothelial carcinoma (7 vs 50 months). However, there was no significant difference in the disease specific 5-year survival rate between patients with squamous cell carcinoma and urothelial carcinoma in the same disease stage. Vascular invasion, microscopic solid tumor pattern and large tumor size had negative prognostic significance in multivariate analyses. Histopathological tumor typ...

  • micropapillary carcinoma of the Renal Pelvis and ureter
    The Journal of Urology, 2006
    Co-Authors: Sten Holmang, Jean Thomsen, Sonny L Johansson
    Abstract:

    Purpose: MPC located in the upper urinary tract is rare with only 2 cases reported to date. We report clinical and histopathological data on 26 patients to increase the knowledge of this rare entity.Materials and Methods: A clinical and histopathological review was performed in 943 patients with a neoplasm in the Renal Pelvis or ureter, diagnosed between 1971 and 1998. We identified 26 patients with MPC. No patients were alive at the end of the study.Results: Of the patients 11 had greater than 50% MPC and 15 had focal MPC (at least 10%). The incidence was 2.8%. Median patient age at diagnosis was 69 years (range 54 to 88) and the male-to-female ratio was 17:9. All except 4 patients had stage T3 disease or higher. Carcinoma in situ was identified in 64% of cases and vascular invasion was present in 81%. A total of 20 patients (77%) died of disease and only 7 survived longer than 5 years.Conclusions: The prognosis is poor since most patients with MPC of the Renal Pelvis and ureter initially present with ad...

Fred E Avni - One of the best experts on this subject based on the ideXlab platform.

  • insights into the pathogenesis and natural history of fetuses with Renal Pelvis dilatation
    European Urology, 2005
    Co-Authors: Khalid Ismaili, Michelle Hall, Amy Piepsz, M Alexander, Claude Schulman, Fred E Avni
    Abstract:

    Fetal Renal Pelvis dilatation is a frequent abnormality that has been observed in 4.5% of pregnancies. The majority of these cases have a tendency to resolve during infancy. Nevertheless, fetal Renal Pelvis dilatation may be due to significant structural abnormalities such as pelvi-ureteric junction stenosis or vesico-ureteral reflux that may adversely affect Renal function or cause urinary infection or sepsis. This review article aims to summarize the data regarding fetal Renal Pelvis dilatation and to analyze controversial attitudes in the light of the various lines of practice, and to present rational antenatal and postnatal investigation strategy.

  • current management of infants with fetal Renal Pelvis dilation a survey by french speaking pediatric nephrologists and urologists
    Pediatric Nephrology, 2004
    Co-Authors: Khalid Ismaili, Amy Piepsz, Fred E Avni, Karl Martin Wissing, Pierre Cochat, Didier Aubert, Michelle Hall
    Abstract:

    To analyze the current management recommendations among French-speaking physicians treating infants with antenatal Renal Pelvis dilatation, we surveyed 83 pediatric nephrologists and 68 pediatric urologists by questionnaire. A total of 45 (54%) pediatric nephrologists and 38 (56%) pediatric urologists responded. The threshold for the diagnosis of abnormal fetal Renal Pelvis dilatation was significantly higher among pediatric urologists than nephrologists. All responders perform Renal ultrasound examinations after birth. Postnatal Renal Pelvis dilatation was considered abnormal if the anteroposterior diameter was ≥11±1.9 mm by the pediatric urologists and ≥9±2.9 mm by the pediatric nephrologists (P=0.003). Pediatric urologists were more likely than nephrologists to recommend routine voiding cystourethrography [41% versus 20% (P=0.04)]. Mercaptoacetyl-triglycine renography was the most routinely used tool to achieve functional evaluation during follow-up among the responders. Pediatric urologists were more likely to recommend surgical treatment in dilated kidneys with initial function <40%. In conclusion, pediatric urologists had significantly higher thresholds for the detection of prenatal and neonatal Renal Pelvis dilatation. They also more frequently recommended routine voiding cystourethrography and surgical therapy of dilated kidneys with low function than pediatric nephrologists. The variability in attitudes is most probably due to the absence of clear guidelines based on prospective and controlled trials.

  • results of systematic screening for minor degrees of fetal Renal Pelvis dilatation in an unselected population
    American Journal of Obstetrics and Gynecology, 2003
    Co-Authors: Khalid Ismaili, Michelle Hall, Catherine Donner, Dominique Thomas, Daniele Vermeylen, Fred E Avni
    Abstract:

    Abstract Objective: The purpose of this study was to determine the incidence of minor degrees of Renal Pelvis dilatation that is detected by antenatal ultrasound scanning in an unselected population and its value in the prediction of significant uropathies. Study Design: This prospective study was conducted over a 24-month period. Infants with an anteroposterior pelvic diameter of ≥4 mm in the second trimester and/or ≥7 mm but Results: Pyelectasis was found in 4.5% of 5643 fetuses (1.5% with significant uropathy). Among the 213 infants whose cases were followed, 132 infants (62%) had Renal anomalies, but only 83 infants (39%) had significant uropathies. The ability of the third-trimester Renal Pelvis dilatation to predict Renal abnormalities showed a positive predictive value of 69%. Pyelectasis that was detected only in the second trimester revealed a significant uropathy in 12% of the infants. Conclusion: Pyelectasis was found in 4.5% of fetuses. The third-trimester anteroposterior Renal Pelvis diameter of ≥7 mm was the best ultrasound criterion to predict postnatal uropathies. (Am J Obstet Gynecol 2003;188:242-6.)

Katsusuke Naito - One of the best experts on this subject based on the ideXlab platform.