The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Lidewij Henneman - One of the best experts on this subject based on the ideXlab platform.
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Reproductive Behavior of individuals with increased risk of having a child with retinoblastoma
Clinical Genetics, 2012Co-Authors: Charlotte J Dommering, M M Garvelink, Annette C Moll, J Van Dijk, Saskia M Imhof, Hanne Meijersheijboer, Lidewij HennemanAbstract:Dommering CJ, Garvelink MM, Moll AC, van Dijk J, Imhof SM, Meijers-Heijboer H, Henneman L. Reproductive Behavior of individuals with increased risk of having a child with retinoblastoma. To investigate Reproductive Behavior of individuals at increased risk of having a child with retinoblastoma (Rb), we conducted a cross-sectional questionnaire survey among 118 counselees visiting the Clinical Genetics Department of the National Rb Center in the Netherlands. The recurrence risk for counselees ranged from <1% to 50%. The response rate was 69%. Of 43 respondents considering having children after becoming aware of their increased risk, Rb influenced Reproductive Behavior for 25 (58%), of whom 14 had a recurrence risk <3%. Twenty of these 25 decided against having more children and 5 used prenatal diagnosis. Eighteen of the 43 respondents did not use any of the alternative Reproductive options and had children (or more children), although half indicated having had doubts about their decisions. Multiple logistic regression showed that only perceived risk (p = 0.003) was significantly associated with Rb influencing Reproductive Behavior. Of 17 respondents planning children (or more children), 11 (65%) considered using one of the alternative Reproductive options. We conclude that Reproductive Behavior is greatly influenced by Rb and that perceived risk, not objective risk, is the most important factor of influence. It is important to offer individuals at increased risk continued access to genetic counseling, even when this risk is small.
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Reproductive Behavior of individuals with increased risk of having a child with retinoblastoma.
Clinical genetics, 2011Co-Authors: Charlotte J Dommering, M M Garvelink, Annette C Moll, J Van Dijk, Saskia M Imhof, Hanne Meijers-heijboer, Lidewij HennemanAbstract:To investigate Reproductive Behavior of individuals at increased risk of having a child with retinoblastoma (Rb), we conducted a cross-sectional questionnaire survey among 118 counselees visiting the Clinical Genetics Department of the National Rb Center in the Netherlands. The recurrence risk for counselees ranged from
Cornelia I. Bargmann - One of the best experts on this subject based on the ideXlab platform.
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oxytocin vasopressin related peptides have an ancient role in Reproductive Behavior
Science, 2012Co-Authors: Jennifer L. Garrison, Evan Z. Macosko, Samantha Bernstein, Navin Pokala, Dirk R. Albrecht, Cornelia I. BargmannAbstract:Many biological functions are conserved, but the extent to which conservation applies to integrative Behaviors is unknown. Vasopressin and oxytocin neuropeptides are strongly implicated in mammalian Reproductive and social Behaviors, yet rodent loss-of-function mutants have relatively subtle Behavioral defects. Here we identify an oxytocin/vasopressin-like signaling system in Caenorhabditis elegans, consisting of a peptide and two receptors that are expressed in sexually dimorphic patterns. Males lacking the peptide or its receptors perform poorly in Reproductive Behaviors, including mate search, mate recognition, and mating, but other sensorimotor Behaviors are intact. Quantitative analysis indicates that mating motor patterns are fragmented and inefficient in mutants, suggesting that oxytocin/vasopressin peptides increase the coherence of mating Behaviors. These results indicate that conserved molecules coordinate diverse Behavioral motifs in Reproductive Behavior.
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Oxytocin/Vasopressin-Related Peptides Have an Ancient Role in Reproductive Behavior
Science (New York N.Y.), 2012Co-Authors: Jennifer L. Garrison, Evan Z. Macosko, Samantha Bernstein, Navin Pokala, Dirk R. Albrecht, Cornelia I. BargmannAbstract:Many biological functions are conserved, but the extent to which conservation applies to integrative Behaviors is unknown. Vasopressin and oxytocin neuropeptides are strongly implicated in mammalian Reproductive and social Behaviors, yet rodent loss-of-function mutants have relatively subtle Behavioral defects. Here we identify an oxytocin/vasopressin-like signaling system in Caenorhabditis elegans, consisting of a peptide and two receptors that are expressed in sexually dimorphic patterns. Males lacking the peptide or its receptors perform poorly in Reproductive Behaviors, including mate search, mate recognition, and mating, but other sensorimotor Behaviors are intact. Quantitative analysis indicates that mating motor patterns are fragmented and inefficient in mutants, suggesting that oxytocin/vasopressin peptides increase the coherence of mating Behaviors. These results indicate that conserved molecules coordinate diverse Behavioral motifs in Reproductive Behavior.
Henry P. David - One of the best experts on this subject based on the ideXlab platform.
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Psychology, population, and Reproductive Behavior.
The American psychologist, 2003Co-Authors: Henry P. David, Nancy Felipe RussoAbstract:This special section on international perspectives in psychology focuses on population issues and Reproductive Behavior across national and cultural boundaries, emphasizing the responsibility of psychologists and colleagues in related disciplines to generate and communicate culturally mindful findings likely to shape public health policy and improve human well-being. After considering the historical and policy context, it highlights internationally collaborative research projects in the Czech Republic, Egypt, Mexico, and the United States that address Reproductive Behavior, women's roles and status, responsible parenthood, and abortion legislation in terms of cultural context, gender equity, the needs of adolescents, and public health policy. The articles illustrate the importance of the cultural context within which psychological research is conducted and how psychology can be informed by international perspectives.
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Reproductive rights and Reproductive Behavior. Clash or convergence of private values and public policies
The American psychologist, 1994Co-Authors: Henry P. DavidAbstract:Using a rational scientific approach upholding public health values, this article notes experience gained from 25 years of cooperative transnational research on Reproductive Behavior. An overview of world population trends is followed by discussions of Reproductive rights as a human right, the utility of acceptability studies of modern methods of fertility regulation, and findings from research on psychological responses to abortion, long-term developmental effects of compulsory pregnancy, and the use of incentives and disincentives to influence family size. There is also consideration of the clash between private values and public policy on Reproductive Behavior in the United States and the convergence achieved in Denmark and the Netherlands, where rates of unintended pregnancy are among the world's lowest.
Wendy Portillo - One of the best experts on this subject based on the ideXlab platform.
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Activation of progestin receptors in female Reproductive Behavior: Interactions with neurotransmitters.
Frontiers in neuroendocrinology, 2010Co-Authors: Shaila K. Mani, Wendy PortilloAbstract:The steroid hormone, progesterone (P), modulates neuroendocrine functions in the central nervous system resulting in alterations in physiology and Reproductive Behavior in female mammals. A wide body of evidence indicates that these neural effects of P are predominantly mediated via their intracellular progestin receptors (PRs) functioning as "ligand-dependent" transcription factors in the steroid-sensitive neurons regulating genes and genomic networks. In addition to P, intracellular PRs can be activated by neurotransmitters, growth factors and cyclic nucleotides in a ligand-independent manner via crosstalk and convergence of pathways. Furthermore, recent studies indicate that rapid signaling events associated with membrane PRs and/or extra-nuclear, cytoplasmic PRs converge with classical PR activated pathways in neuroendocrine regulation of female Reproductive Behavior. The molecular mechanisms, by which multiple signaling pathways converge on PRs to modulate PR-dependent female Reproductive Behavior, are discussed in this review.
Charlotte J Dommering - One of the best experts on this subject based on the ideXlab platform.
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Reproductive Behavior of individuals with increased risk of having a child with retinoblastoma
Clinical Genetics, 2012Co-Authors: Charlotte J Dommering, M M Garvelink, Annette C Moll, J Van Dijk, Saskia M Imhof, Hanne Meijersheijboer, Lidewij HennemanAbstract:Dommering CJ, Garvelink MM, Moll AC, van Dijk J, Imhof SM, Meijers-Heijboer H, Henneman L. Reproductive Behavior of individuals with increased risk of having a child with retinoblastoma. To investigate Reproductive Behavior of individuals at increased risk of having a child with retinoblastoma (Rb), we conducted a cross-sectional questionnaire survey among 118 counselees visiting the Clinical Genetics Department of the National Rb Center in the Netherlands. The recurrence risk for counselees ranged from <1% to 50%. The response rate was 69%. Of 43 respondents considering having children after becoming aware of their increased risk, Rb influenced Reproductive Behavior for 25 (58%), of whom 14 had a recurrence risk <3%. Twenty of these 25 decided against having more children and 5 used prenatal diagnosis. Eighteen of the 43 respondents did not use any of the alternative Reproductive options and had children (or more children), although half indicated having had doubts about their decisions. Multiple logistic regression showed that only perceived risk (p = 0.003) was significantly associated with Rb influencing Reproductive Behavior. Of 17 respondents planning children (or more children), 11 (65%) considered using one of the alternative Reproductive options. We conclude that Reproductive Behavior is greatly influenced by Rb and that perceived risk, not objective risk, is the most important factor of influence. It is important to offer individuals at increased risk continued access to genetic counseling, even when this risk is small.
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Reproductive Behavior of individuals with increased risk of having a child with retinoblastoma.
Clinical genetics, 2011Co-Authors: Charlotte J Dommering, M M Garvelink, Annette C Moll, J Van Dijk, Saskia M Imhof, Hanne Meijers-heijboer, Lidewij HennemanAbstract:To investigate Reproductive Behavior of individuals at increased risk of having a child with retinoblastoma (Rb), we conducted a cross-sectional questionnaire survey among 118 counselees visiting the Clinical Genetics Department of the National Rb Center in the Netherlands. The recurrence risk for counselees ranged from
