The Experts below are selected from a list of 36540 Experts worldwide ranked by ideXlab platform
Jan J Piek - One of the best experts on this subject based on the ideXlab platform.
-
influence of percutaneous coronary intervention on coronary microvascular Resistance Index
Circulation, 2005Co-Authors: Bartjan Verhoeff, Michiel Voskuil, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Martijn Meuwissen, Bektas Atasever, Karel T Koch, Jos A E Spaan, Jan J PiekAbstract:Background— Coronary microvascular Resistance during maximal hyperemia is generally assumed to be unaffected by percutaneous coronary interventions (PCIs). We assessed a velocity-based Index of hyperemic microvascular Resistance (h-MRv) by using prototypes of a novel, dual-sensor (Doppler velocity and pressure)–equipped guidewire before and after PCI to test this hypothesis. Methods and Results— Aortic pressure, flow velocity (h-v), and pressure (h-Pd) distal to 24 coronary lesions were measured simultaneously during maximal hyperemia induced by intracoronary adenosine. Measurements were obtained in the reference vessel before PCI and in the target vessel before and after PCI, stenting, and ultrasound-guided, upsized stenting. h-Pd increased from 57.9±17.0 to 85.5±15.6 mm Hg, and h-MRv (ie, h-Pd/h-v) decreased from 2.74±1.40 to 1.58±0.61 mm Hg · cm−1 · s after stenting (both P<0.001). The reduction in h-MRv accounted for 34% of the decrease in total coronary Resistance achieved by PCI. h-MRv of the target...
-
hyperemic stenosis Resistance Index for evaluation of functional coronary lesion severity
Circulation, 2002Co-Authors: Martijn Meuwissen, Steven A.j. Chamuleau, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Karel T Koch, Jos A E Spaan, Berthe L F Van Ecksmit, Jan J PiekAbstract:Background— Both coronary blood flow velocity reserve (CFVR) and myocardial fractional flow reserve (FFR) are used to evaluate the hemodynamic severity of coronary lesions. However, discordant resu...
Michiel Voskuil - One of the best experts on this subject based on the ideXlab platform.
-
head to head comparison of basal stenosis Resistance Index instantaneous wave free ratio and fractional flow reserve diagnostic accuracy for stenosis specific myocardial ischaemia
Eurointervention, 2015Co-Authors: Van De Hoef Tp, Froukje Nolte, Steven A.j. Chamuleau, M Meuwissen, Javier Escaned, Ricardo Petraco, Van Lavieren, Mauro Echavarriapinto, S S Nijjer, Michiel VoskuilAbstract:Abstract We sought to compare the diagnostic accuracy of basal stenosis Resistance Index (BSR), instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) for stenosis-specific myocardial ischaemia identified by means of a combined reference standard of myocardial perfusion scintigraphy and the hyperaemic stenosis Resistance Index. BSR and FFR were determined for 299 coronary stenoses, iFR was determined for 85 coronary stenoses (iFR cohort). The discriminative value for stenosis-specific myocardial ischaemia was compared by means of the area under the receiver operating characteristic (ROC) curves (AUC). Classification agreement with the reference standard was determined according to ROC curve-derived ischaemic cut-off values, as well as according to clinical cut-off values, equivalent to the 0.80 FFR cut-off. Across all stenoses, the discriminative value of BSR and FFR was equivalent (AUC: 0.90 and 0.91, respectively, p=0.46). In the iFR cohort, the discriminative value was equivalent for BSR, iFR, and FFR (AUC: 0.88, 0.84, and 0.88, respectively; p≥0.20 for all). At both ischaemic as well as clinical cut-off values, classification agreement with the reference standard was equivalent for BSR and FFR across all stenoses, as well as for BSR, iFR, and FFR in the iFR cohort. BSR, iFR, and FFR have equivalent diagnostic accuracy for the detection of ischaemia-generating coronary stenoses.
-
DIAGNOSTIC ACCURACY OF BASAL STENOSIS Resistance Index FOR MYOCARDIAL ISCHEMIA IDENTIFIED BY FRACTIONAL FLOW RESERVE AND IMPLICATIONS OF STENOSIS Resistance Index DETERMINED AT SUB–MAXIMALLY ELEVATED CORONARY FLOW RATES
Journal of the American College of Cardiology, 2013Co-Authors: Tim P. Van De Hoef, Froukje Nolte, Peter Damman, Ronak Delewi, Mariëlla E.c.j. Hassell, Steven A.j. Chamuleau, Michiel Voskuil, José P.s. Henriques, Robbert J. De Winter, Jan G.p. TijssenAbstract:Basal stenosis Resistance Index (BSR) is a novel adenosine–free Index with a diagnostic accuracy for myocardial ischemia on perfusion scintigraphy mirroring fractional flow reserve (FFR). However, its diagnostic accuracy for myocardial ischemia identified by FFR is unknown, and the diagnostic
-
influence of percutaneous coronary intervention on coronary microvascular Resistance Index
Circulation, 2005Co-Authors: Bartjan Verhoeff, Michiel Voskuil, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Martijn Meuwissen, Bektas Atasever, Karel T Koch, Jos A E Spaan, Jan J PiekAbstract:Background— Coronary microvascular Resistance during maximal hyperemia is generally assumed to be unaffected by percutaneous coronary interventions (PCIs). We assessed a velocity-based Index of hyperemic microvascular Resistance (h-MRv) by using prototypes of a novel, dual-sensor (Doppler velocity and pressure)–equipped guidewire before and after PCI to test this hypothesis. Methods and Results— Aortic pressure, flow velocity (h-v), and pressure (h-Pd) distal to 24 coronary lesions were measured simultaneously during maximal hyperemia induced by intracoronary adenosine. Measurements were obtained in the reference vessel before PCI and in the target vessel before and after PCI, stenting, and ultrasound-guided, upsized stenting. h-Pd increased from 57.9±17.0 to 85.5±15.6 mm Hg, and h-MRv (ie, h-Pd/h-v) decreased from 2.74±1.40 to 1.58±0.61 mm Hg · cm−1 · s after stenting (both P<0.001). The reduction in h-MRv accounted for 34% of the decrease in total coronary Resistance achieved by PCI. h-MRv of the target...
Jan G.p. Tijssen - One of the best experts on this subject based on the ideXlab platform.
-
DIAGNOSTIC ACCURACY OF BASAL STENOSIS Resistance Index FOR MYOCARDIAL ISCHEMIA IDENTIFIED BY FRACTIONAL FLOW RESERVE AND IMPLICATIONS OF STENOSIS Resistance Index DETERMINED AT SUB–MAXIMALLY ELEVATED CORONARY FLOW RATES
Journal of the American College of Cardiology, 2013Co-Authors: Tim P. Van De Hoef, Froukje Nolte, Peter Damman, Ronak Delewi, Mariëlla E.c.j. Hassell, Steven A.j. Chamuleau, Michiel Voskuil, José P.s. Henriques, Robbert J. De Winter, Jan G.p. TijssenAbstract:Basal stenosis Resistance Index (BSR) is a novel adenosine–free Index with a diagnostic accuracy for myocardial ischemia on perfusion scintigraphy mirroring fractional flow reserve (FFR). However, its diagnostic accuracy for myocardial ischemia identified by FFR is unknown, and the diagnostic
-
influence of percutaneous coronary intervention on coronary microvascular Resistance Index
Circulation, 2005Co-Authors: Bartjan Verhoeff, Michiel Voskuil, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Martijn Meuwissen, Bektas Atasever, Karel T Koch, Jos A E Spaan, Jan J PiekAbstract:Background— Coronary microvascular Resistance during maximal hyperemia is generally assumed to be unaffected by percutaneous coronary interventions (PCIs). We assessed a velocity-based Index of hyperemic microvascular Resistance (h-MRv) by using prototypes of a novel, dual-sensor (Doppler velocity and pressure)–equipped guidewire before and after PCI to test this hypothesis. Methods and Results— Aortic pressure, flow velocity (h-v), and pressure (h-Pd) distal to 24 coronary lesions were measured simultaneously during maximal hyperemia induced by intracoronary adenosine. Measurements were obtained in the reference vessel before PCI and in the target vessel before and after PCI, stenting, and ultrasound-guided, upsized stenting. h-Pd increased from 57.9±17.0 to 85.5±15.6 mm Hg, and h-MRv (ie, h-Pd/h-v) decreased from 2.74±1.40 to 1.58±0.61 mm Hg · cm−1 · s after stenting (both P<0.001). The reduction in h-MRv accounted for 34% of the decrease in total coronary Resistance achieved by PCI. h-MRv of the target...
-
hyperemic stenosis Resistance Index for evaluation of functional coronary lesion severity
Circulation, 2002Co-Authors: Martijn Meuwissen, Steven A.j. Chamuleau, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Karel T Koch, Jos A E Spaan, Berthe L F Van Ecksmit, Jan J PiekAbstract:Background— Both coronary blood flow velocity reserve (CFVR) and myocardial fractional flow reserve (FFR) are used to evaluate the hemodynamic severity of coronary lesions. However, discordant resu...
Robbert J. De Winter - One of the best experts on this subject based on the ideXlab platform.
-
DIAGNOSTIC ACCURACY OF BASAL STENOSIS Resistance Index FOR MYOCARDIAL ISCHEMIA IDENTIFIED BY FRACTIONAL FLOW RESERVE AND IMPLICATIONS OF STENOSIS Resistance Index DETERMINED AT SUB–MAXIMALLY ELEVATED CORONARY FLOW RATES
Journal of the American College of Cardiology, 2013Co-Authors: Tim P. Van De Hoef, Froukje Nolte, Peter Damman, Ronak Delewi, Mariëlla E.c.j. Hassell, Steven A.j. Chamuleau, Michiel Voskuil, José P.s. Henriques, Robbert J. De Winter, Jan G.p. TijssenAbstract:Basal stenosis Resistance Index (BSR) is a novel adenosine–free Index with a diagnostic accuracy for myocardial ischemia on perfusion scintigraphy mirroring fractional flow reserve (FFR). However, its diagnostic accuracy for myocardial ischemia identified by FFR is unknown, and the diagnostic
-
influence of percutaneous coronary intervention on coronary microvascular Resistance Index
Circulation, 2005Co-Authors: Bartjan Verhoeff, Michiel Voskuil, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Martijn Meuwissen, Bektas Atasever, Karel T Koch, Jos A E Spaan, Jan J PiekAbstract:Background— Coronary microvascular Resistance during maximal hyperemia is generally assumed to be unaffected by percutaneous coronary interventions (PCIs). We assessed a velocity-based Index of hyperemic microvascular Resistance (h-MRv) by using prototypes of a novel, dual-sensor (Doppler velocity and pressure)–equipped guidewire before and after PCI to test this hypothesis. Methods and Results— Aortic pressure, flow velocity (h-v), and pressure (h-Pd) distal to 24 coronary lesions were measured simultaneously during maximal hyperemia induced by intracoronary adenosine. Measurements were obtained in the reference vessel before PCI and in the target vessel before and after PCI, stenting, and ultrasound-guided, upsized stenting. h-Pd increased from 57.9±17.0 to 85.5±15.6 mm Hg, and h-MRv (ie, h-Pd/h-v) decreased from 2.74±1.40 to 1.58±0.61 mm Hg · cm−1 · s after stenting (both P<0.001). The reduction in h-MRv accounted for 34% of the decrease in total coronary Resistance achieved by PCI. h-MRv of the target...
-
hyperemic stenosis Resistance Index for evaluation of functional coronary lesion severity
Circulation, 2002Co-Authors: Martijn Meuwissen, Steven A.j. Chamuleau, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Karel T Koch, Jos A E Spaan, Berthe L F Van Ecksmit, Jan J PiekAbstract:Background— Both coronary blood flow velocity reserve (CFVR) and myocardial fractional flow reserve (FFR) are used to evaluate the hemodynamic severity of coronary lesions. However, discordant resu...
Martijn Meuwissen - One of the best experts on this subject based on the ideXlab platform.
-
influence of percutaneous coronary intervention on coronary microvascular Resistance Index
Circulation, 2005Co-Authors: Bartjan Verhoeff, Michiel Voskuil, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Martijn Meuwissen, Bektas Atasever, Karel T Koch, Jos A E Spaan, Jan J PiekAbstract:Background— Coronary microvascular Resistance during maximal hyperemia is generally assumed to be unaffected by percutaneous coronary interventions (PCIs). We assessed a velocity-based Index of hyperemic microvascular Resistance (h-MRv) by using prototypes of a novel, dual-sensor (Doppler velocity and pressure)–equipped guidewire before and after PCI to test this hypothesis. Methods and Results— Aortic pressure, flow velocity (h-v), and pressure (h-Pd) distal to 24 coronary lesions were measured simultaneously during maximal hyperemia induced by intracoronary adenosine. Measurements were obtained in the reference vessel before PCI and in the target vessel before and after PCI, stenting, and ultrasound-guided, upsized stenting. h-Pd increased from 57.9±17.0 to 85.5±15.6 mm Hg, and h-MRv (ie, h-Pd/h-v) decreased from 2.74±1.40 to 1.58±0.61 mm Hg · cm−1 · s after stenting (both P<0.001). The reduction in h-MRv accounted for 34% of the decrease in total coronary Resistance achieved by PCI. h-MRv of the target...
-
hyperemic stenosis Resistance Index for evaluation of functional coronary lesion severity
Circulation, 2002Co-Authors: Martijn Meuwissen, Steven A.j. Chamuleau, Robbert J. De Winter, Jan G.p. Tijssen, Maria Siebes, Karel T Koch, Jos A E Spaan, Berthe L F Van Ecksmit, Jan J PiekAbstract:Background— Both coronary blood flow velocity reserve (CFVR) and myocardial fractional flow reserve (FFR) are used to evaluate the hemodynamic severity of coronary lesions. However, discordant resu...