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C. Chiquet - One of the best experts on this subject based on the ideXlab platform.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular inflammation secondary to syphilis infection
Acta Ophthalmologica Scandinavica, 2007Co-Authors: C. Puech, C. Chiquet, Patricia Pavese, Laurence Bouillet, Jp RomanetAbstract:Purpose: to report ocular inflammation secondary to syphilis infection in a tertiary center. Methods: Within a prospective study (2 years, 2005-2007), we collected data on 7 male patients with ocular syphilis. Diagnosis was based on serology tests on blood sample and/or cerebrospinal fluid. All patients underwent a check up for ocular inflammation to rule out another etiological diagnosis and to detect another sexually transmitted infection. Results: Coinfection with human immunodeficiency virus was reported in 4 patients, with a CD4 T lymphocyte count greater than 300/mm3 in all cases. The ocular lesions were variable ; chorioretinitis (1 eye), retinal necrosis (2), panuveitis with macular edema (1), episcleritis (1), anterior Optic Neuropathy (1), and Retrobulbar Optic Neuropathy (1). Infection of the cerebrospinal fluid was detected in 4/4 cases. The lumbar puncture was refused in 3 cases. In all cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent. Only one patient with the anterior Optic Neuropathy required systemic steroid therapy associated with antibiotics. Sequelae were a sectorial atrophy of the Optic nerve (1 eye), and abnormalities of the retinal pigment epithelium (3 eyes). 6/7 patients were treated with ceftriaxone 2g/day during 3 weeks, with a good tolerance. One patient was treated with penicillin G. Conclusions: All patients with ocular syphilis exhibited a functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. In our area, the incidence of syphilis increases in immunocompetent and immunocompromised patients. As a great imitator, syphilis should be considered in all patients with uveitis or Optic neuritis, especially in men with unprotected sexual behavior.
C. Puech - One of the best experts on this subject based on the ideXlab platform.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular inflammation secondary to syphilis infection
Acta Ophthalmologica Scandinavica, 2007Co-Authors: C. Puech, C. Chiquet, Patricia Pavese, Laurence Bouillet, Jp RomanetAbstract:Purpose: to report ocular inflammation secondary to syphilis infection in a tertiary center. Methods: Within a prospective study (2 years, 2005-2007), we collected data on 7 male patients with ocular syphilis. Diagnosis was based on serology tests on blood sample and/or cerebrospinal fluid. All patients underwent a check up for ocular inflammation to rule out another etiological diagnosis and to detect another sexually transmitted infection. Results: Coinfection with human immunodeficiency virus was reported in 4 patients, with a CD4 T lymphocyte count greater than 300/mm3 in all cases. The ocular lesions were variable ; chorioretinitis (1 eye), retinal necrosis (2), panuveitis with macular edema (1), episcleritis (1), anterior Optic Neuropathy (1), and Retrobulbar Optic Neuropathy (1). Infection of the cerebrospinal fluid was detected in 4/4 cases. The lumbar puncture was refused in 3 cases. In all cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent. Only one patient with the anterior Optic Neuropathy required systemic steroid therapy associated with antibiotics. Sequelae were a sectorial atrophy of the Optic nerve (1 eye), and abnormalities of the retinal pigment epithelium (3 eyes). 6/7 patients were treated with ceftriaxone 2g/day during 3 weeks, with a good tolerance. One patient was treated with penicillin G. Conclusions: All patients with ocular syphilis exhibited a functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. In our area, the incidence of syphilis increases in immunocompetent and immunocompromised patients. As a great imitator, syphilis should be considered in all patients with uveitis or Optic neuritis, especially in men with unprotected sexual behavior.
Jp Romanet - One of the best experts on this subject based on the ideXlab platform.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular inflammation secondary to syphilis infection
Acta Ophthalmologica Scandinavica, 2007Co-Authors: C. Puech, C. Chiquet, Patricia Pavese, Laurence Bouillet, Jp RomanetAbstract:Purpose: to report ocular inflammation secondary to syphilis infection in a tertiary center. Methods: Within a prospective study (2 years, 2005-2007), we collected data on 7 male patients with ocular syphilis. Diagnosis was based on serology tests on blood sample and/or cerebrospinal fluid. All patients underwent a check up for ocular inflammation to rule out another etiological diagnosis and to detect another sexually transmitted infection. Results: Coinfection with human immunodeficiency virus was reported in 4 patients, with a CD4 T lymphocyte count greater than 300/mm3 in all cases. The ocular lesions were variable ; chorioretinitis (1 eye), retinal necrosis (2), panuveitis with macular edema (1), episcleritis (1), anterior Optic Neuropathy (1), and Retrobulbar Optic Neuropathy (1). Infection of the cerebrospinal fluid was detected in 4/4 cases. The lumbar puncture was refused in 3 cases. In all cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent. Only one patient with the anterior Optic Neuropathy required systemic steroid therapy associated with antibiotics. Sequelae were a sectorial atrophy of the Optic nerve (1 eye), and abnormalities of the retinal pigment epithelium (3 eyes). 6/7 patients were treated with ceftriaxone 2g/day during 3 weeks, with a good tolerance. One patient was treated with penicillin G. Conclusions: All patients with ocular syphilis exhibited a functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. In our area, the incidence of syphilis increases in immunocompetent and immunocompromised patients. As a great imitator, syphilis should be considered in all patients with uveitis or Optic neuritis, especially in men with unprotected sexual behavior.
Patricia Pavese - One of the best experts on this subject based on the ideXlab platform.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular manifestations of syphilis: recent cases over a 2.5-year period.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2010Co-Authors: C. Puech, Patricia Pavese, Jp Romanet, Stéphane Gennai, Isabelle Pelloux, Max Maurin, C. ChiquetAbstract:BACKGROUND: The ocular manifestations of syphilis are protean and can affect every structure of the eye. There has been a recent increase of syphilis infection in Europe. We report recent cases of ocular syphilis infection in a tertiary center. METHODS: During a 2.5-year period (2005-2007) we collected the medical records of eight male patients with ocular syphilis. The diagnosis was based on serological tests on blood samples and cerebrospinal fluid. All patients underwent a check-up to rule out another etiological diagnosis and to detect the presence of any other sexually transmitted infections. RESULTS: The ocular lesions included: chorioretinitis (one case), retinitis (two cases), panuveitis with macular edema (two cases), episcleritis (one case), anterior Optic neuritis (one case), and Retrobulbar Optic Neuropathy (one case). Infection of the cerebrospinal fluid was detected in three of the five patients tested. In six cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent at the 6-month follow-up visit. Co-infection with human immunodeficiency virus was reported in five patients, with a CD4 T lymphocyte count greater than 300/mm(3). Most of the patients were treated with parenteral ceftriaxone (1 g daily) for 3 weeks with good tolerance. One patient was treated with intravenous penicillin G (18 MUI daily). Only one patient with anterior Optic neuritis required systemic steroid therapy associated with antibiotics. Sequelae included sectorial atrophy of the Optic nerve with visual field loss (n = 1) and abnormalities of the retinal pigment epithelium (n = 3). CONCLUSIONS: All patients with ocular syphilis exhibited functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. As a great imitator, syphilis should be considered in all patients with uveitis, scleritis, episcleritis, or Optic neuritis, especially in men with high-risk sexual behavior.
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Ocular inflammation secondary to syphilis infection
Acta Ophthalmologica Scandinavica, 2007Co-Authors: C. Puech, C. Chiquet, Patricia Pavese, Laurence Bouillet, Jp RomanetAbstract:Purpose: to report ocular inflammation secondary to syphilis infection in a tertiary center. Methods: Within a prospective study (2 years, 2005-2007), we collected data on 7 male patients with ocular syphilis. Diagnosis was based on serology tests on blood sample and/or cerebrospinal fluid. All patients underwent a check up for ocular inflammation to rule out another etiological diagnosis and to detect another sexually transmitted infection. Results: Coinfection with human immunodeficiency virus was reported in 4 patients, with a CD4 T lymphocyte count greater than 300/mm3 in all cases. The ocular lesions were variable ; chorioretinitis (1 eye), retinal necrosis (2), panuveitis with macular edema (1), episcleritis (1), anterior Optic Neuropathy (1), and Retrobulbar Optic Neuropathy (1). Infection of the cerebrospinal fluid was detected in 4/4 cases. The lumbar puncture was refused in 3 cases. In all cases, the inflammation was unilateral, and the anatomical and functional prognosis was excellent. Only one patient with the anterior Optic Neuropathy required systemic steroid therapy associated with antibiotics. Sequelae were a sectorial atrophy of the Optic nerve (1 eye), and abnormalities of the retinal pigment epithelium (3 eyes). 6/7 patients were treated with ceftriaxone 2g/day during 3 weeks, with a good tolerance. One patient was treated with penicillin G. Conclusions: All patients with ocular syphilis exhibited a functional improvement and resolution of ocular inflammation after a specific antibiotic treatment. In our area, the incidence of syphilis increases in immunocompetent and immunocompromised patients. As a great imitator, syphilis should be considered in all patients with uveitis or Optic neuritis, especially in men with unprotected sexual behavior.
Pouya N. Dayani - One of the best experts on this subject based on the ideXlab platform.
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Punctate inner choroidopathy and Optic Neuropathy: simultaneous presentation in a patient - a case report.
Journal of ophthalmic inflammation and infection, 2013Co-Authors: Michelle V Carle, David S. Boyer, Pouya N. DayaniAbstract:Background We present a case of a patient initially presenting with multifocal choroiditis (MFC) in one eye. She subsequently developed lesions most consistent with punctate inner choroidopathy (PIC) in the contralateral eye, followed by acute vision loss from Retrobulbar Optic Neuropathy. Optic Neuropathy has been well described in the setting of MFC. There is, however, only one report of its association with PIC. Punctate inner choroidopathy and MFC have many similarities, with visual loss generally resulting from choroidal neovascularization. In this case, the patient had significant visual loss from presumed Retrobulbar Optic Neuropathy.
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Punctate inner choroidopathy and Optic Neuropathy: simultaneous presentation in a patient - a case report
Journal of Ophthalmic Inflammation and Infection, 2013Co-Authors: Michelle V Carle, David S. Boyer, Pouya N. DayaniAbstract:Background We present a case of a patient initially presenting with multifocal choroiditis (MFC) in one eye. She subsequently developed lesions most consistent with punctate inner choroidopathy (PIC) in the contralateral eye, followed by acute vision loss from Retrobulbar Optic Neuropathy. Optic Neuropathy has been well described in the setting of MFC. There is, however, only one report of its association with PIC. Punctate inner choroidopathy and MFC have many similarities, with visual loss generally resulting from choroidal neovascularization. In this case, the patient had significant visual loss from presumed Retrobulbar Optic Neuropathy. Findings The patient responded well to immunomodulation with subsequent return of vision to baseline. Conclusions Multifocal choroiditis and punctate inner choroidopathy may be a spectrum of the same disease with many overlapping presentations, including Optic Neuropathy. Good visual recovery and remission were attained with mycophenolate mofetil and systemic corticosteroid treatment.