The Experts below are selected from a list of 318 Experts worldwide ranked by ideXlab platform
Kate Dixon - One of the best experts on this subject based on the ideXlab platform.
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Bronchoscopic NdYAG laser treatment in lung cancer, 30 years on: an institutional review
Lasers in Medical Science, 2006Co-Authors: K Moghissi, Kate DixonAbstract:We review our 21-year experience in bronchoscopic NdYAG laser for lung cancer and the relevant literature. Patients totaling 1,159 received 2,235 bronchoscopic treatments. The pre-requisite for laser therapy was the presence of >50% obstruction of the bronchial lumen. We use the Rigid Bronchoscope, with the patient under general anaesthetic and application of laser in its non-contact mode. Two patients (0.17%) died following the procedure, and 4.8% had non-fatal complications. Four to 6 weeks after treatment there was a 48% increase in bronchial calibre and an increase of 27% (mean) in forced vital capacity and 15% (mean) in forced expiratory volume in one second, respectively. These paralleled symptomatic relief and chest X-ray improvement. Literature review indicated results similar to ours in those centres with high volume activity. Thirty years on, bronchoscopic YAG laser therapy of lung cancer still has an important role in palliation of patients with inoperable lung cancer, particularly those requiring immediate relief of bronchial obstruction.
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photodynamic therapy pdt for bronchial carcinoma with the use of Rigid Bronchoscope
Lasers in Medical Science, 1992Co-Authors: K Moghissi, R J Parsons, Kate DixonAbstract:Endoscopic PDT was undertaken in nine patients with inoperable bronchial cancer. Eight patients had advanced metastatic disease and one was unsuitablefor surgery on account of age, respiratory function and location of tumour. Patients were injected with Photofrin II (no. 7) or Polyhaematoporphyrin derivative (no. 2) at 2 mg kg−1 of bodyweight before being irradiated 48 h later by 630 nm red light generated by a copper vapour laser (Oxford Lasers) for 200 J cm−1 tumour tissue. Treatment was undertaken under general anaesthetic using a Rigid Bronchoscope for ventilating and suction purposes with the fibre optic instrument introduced through the Rigid Bronchoscope for localization of tumour and placement of the diffusing fibre. One patient died 2 months after treatment from carcinomatosis. One patient had total response with negative histology for 10 months. All other patients with substantial endobronchial obstructive lesions had partial response with significant reduction in percentage obstruction and improved pulmonary function. There have been no post-operative complications.
K Moghissi - One of the best experts on this subject based on the ideXlab platform.
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Thorax 1986;41:485-486 A new bronchoscopy set for laser therapy
2016Co-Authors: K Moghissi, T Jessop, Mary DenchAbstract:Bronchoscopic laser therapy is now an established method of relieving neoplastic tracheobronchial obstructions. Much of the previous work, however, has been done with the flexible fibreoptic Bronchoscope in conscious patients, under sedation and local anaesthesia. Besides the obvious discom-fort to the patient the use of the flexible fibreoptic bron-choscope for laser therapy under local anaesthesia has short-comings related to the Bronchoscope itself. These include the inadequate provision for suction and the difficulty of removing debris, both ofwhich adversely affect the efficiency of the operation. Some operators place a Rigid Bronchoscope first, through which they then introduce the flexible fibreoptic Bronchoscope, to ventilate the patient, or to aspirate the tracheobronchial secretions through the Rigid Bronchoscope intermittently ' (or both); but this is a rather cumbersome manoeuvre. We have therefore designed a new bronchoscopic set for laser therapy that overcomes these difficulties. ii
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Bronchoscopic NdYAG laser treatment in lung cancer, 30 years on: an institutional review
Lasers in Medical Science, 2006Co-Authors: K Moghissi, Kate DixonAbstract:We review our 21-year experience in bronchoscopic NdYAG laser for lung cancer and the relevant literature. Patients totaling 1,159 received 2,235 bronchoscopic treatments. The pre-requisite for laser therapy was the presence of >50% obstruction of the bronchial lumen. We use the Rigid Bronchoscope, with the patient under general anaesthetic and application of laser in its non-contact mode. Two patients (0.17%) died following the procedure, and 4.8% had non-fatal complications. Four to 6 weeks after treatment there was a 48% increase in bronchial calibre and an increase of 27% (mean) in forced vital capacity and 15% (mean) in forced expiratory volume in one second, respectively. These paralleled symptomatic relief and chest X-ray improvement. Literature review indicated results similar to ours in those centres with high volume activity. Thirty years on, bronchoscopic YAG laser therapy of lung cancer still has an important role in palliation of patients with inoperable lung cancer, particularly those requiring immediate relief of bronchial obstruction.
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photodynamic therapy pdt for bronchial carcinoma with the use of Rigid Bronchoscope
Lasers in Medical Science, 1992Co-Authors: K Moghissi, R J Parsons, Kate DixonAbstract:Endoscopic PDT was undertaken in nine patients with inoperable bronchial cancer. Eight patients had advanced metastatic disease and one was unsuitablefor surgery on account of age, respiratory function and location of tumour. Patients were injected with Photofrin II (no. 7) or Polyhaematoporphyrin derivative (no. 2) at 2 mg kg−1 of bodyweight before being irradiated 48 h later by 630 nm red light generated by a copper vapour laser (Oxford Lasers) for 200 J cm−1 tumour tissue. Treatment was undertaken under general anaesthetic using a Rigid Bronchoscope for ventilating and suction purposes with the fibre optic instrument introduced through the Rigid Bronchoscope for localization of tumour and placement of the diffusing fibre. One patient died 2 months after treatment from carcinomatosis. One patient had total response with negative histology for 10 months. All other patients with substantial endobronchial obstructive lesions had partial response with significant reduction in percentage obstruction and improved pulmonary function. There have been no post-operative complications.
F.g. Cerrai - One of the best experts on this subject based on the ideXlab platform.
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Self-expanding tracheobronchial stents using flexible bronchoscopy. Preliminary clinical experience.
Surgical Endoscopy and Other Interventional Techniques, 1994Co-Authors: P. Spinelli, Emanuele Meroni, F.g. CerraiAbstract:Endoscopic insertion of tracheobronchial stents is indicated to achieve patency of the airway in case of malignant or benign obstructing lesions. Until now, the placement of prostheses has required a Rigid Bronchoscope with specially designed insertion instruments. Self-expanding stents are currently used to treat stenoses of different hollow organs (vessels, urinary tract, gastrointestinal tract, bile duct, respiratory tract). We report the first case of a self-expanding stent implanted in the trachea and right main stem bronchus using flexible videoBronchoscope under local anesthesia. The procedure was easy, safe, effective, and well tolerated. No complications occurred.
Bin Liu - One of the best experts on this subject based on the ideXlab platform.
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emla cream coated on the Rigid Bronchoscope for tracheobronchial foreign body removal in children
Laryngoscope, 2009Co-Authors: Xiaoyun Yang, Bin LiuAbstract:Objectives: Removal of a tracheal or bronchial foreign body is a common emergent surgical procedure in children. The anesthetic management can be challenging. EMLA® Cream (EC) has been widely used to provide topical anesthesia. In the present study, we evaluate the efficacy and safety of EC coated on the Rigid Bronchoscope for tracheobronchial foreign body removal in children undergoing intravenous anesthesia with spontaneous ventilation. Study Design: The authors conducted a randomized, double-blind, placebo-controlled clinical trial. Methods: Thirty patients were randomized to receive either EC or placebo (lubricant ointment) coated on the Rigid Bronchoscope. Intravenous anesthesia and spontaneous ventilation were performed in all patients. Heart rate, blood pressure, pulse oxygen saturation (SpO2) and frequency and degree of breath holding were recorded. After surgery, the bronchoscopist rated overall surgical manipulation as excellent, fair, and poor. The durations of postoperative care were also recorded. Results: Episodes of oxygen desaturation (SpO2 < 90%) occurred in 3/15 (20%) patients in the EC group and in 9/15 (60%) patients in the control group (P < .05). Occurrences and degrees of breath holding were less in the EC group than that in the control group (P < .05). Ranks of surgical manipulation were excellent in 80% of patients in the EC group versus 13% of patients in the control group (P < .05). The durations of postoperative care were shorter in the EC group than that in the control group (P < .05). Conclusions: EC coated on the Rigid Bronchoscope combined with intravenous anesthesia could provide more efficacious and safer anesthesia for tracheobronchial foreign body removal in children under spontaneous ventilation. Laryngoscope, 119:158–161, 2009
Jacopo Vannucci - One of the best experts on this subject based on the ideXlab platform.
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An Alternative Method for Airway Management With Combined Tracheal Intubation and Rigid Bronchoscope
The Annals of Thoracic Surgery, 2019Co-Authors: Francesco Puma, Mattia Meattelli, Miroslawa Kolodziejek, Marina Giuliana Properzi, Rosanna Capozzi, Alberto Matricardi, Lucio Cagini, Jacopo VannucciAbstract:An innovative technique for airway management, using a small-diameter, short-cuffed orotracheal tube for assisting Rigid bronchoscopy in critical airway obstruction is reported. The device, part of the translaryngeal tracheostomy kit, "Fantoni method" (DAR TLT, Covidien, Minneapolis, MN), was placed beyond the stenosis and used in combination with the Rigid Bronchoscope. This procedure improves safety during the management of critical tracheal stenoses because the airway is constantly under the anesthesiologist's control. Consequently, inhalation anesthesia is feasible, use of neuromuscular blockade is possible, end-tidal carbon dioxide monitoring is reliable, and the distal airway is protected from blood and debris soilage during tumor debulking. Surgery is faster because it is uninterrupted.
